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Showing 1 to 12 of 168 entries
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Artificial miRNAs Targeting Mutant Huntingtin Show Preferential Silencing In Vitro and In Vivo.

Molecular therapy. Nucleic acids

Monteys AM, Wilson MJ, Boudreau RL, Spengler RM, Davidson BL.
PMID: 25849618
Mol Ther Nucleic Acids. 2015 Apr 07;4:e234. doi: 10.1038/mtna.2015.7.

Huntington's disease (HD) is a dominantly inherited neurodegenerative disease caused by CAG repeat expansion in exon 1 of huntingtin (HTT). Studies in mouse models of HD with a regulated mutant transgene show that continuous mutant allele expression is required...

Petroleum crude oil analysis using low-temperature plasma mass spectrometry.

Rapid communications in mass spectrometry : RCM

Benassi M, Berisha A, Romão W, Babayev E, Römpp A, Spengler B.
PMID: 23495029
Rapid Commun Mass Spectrom. 2013 Apr 15;27(7):825-34. doi: 10.1002/rcm.6518.

RATIONALE: The analysis of crude oil is a challenging task due to sample complexity. In mass spectrometry, several ionization techniques can be used to perform this task. Herein, we report the use of an atmospheric pressure low-temperature plasma (LTP)...

How psychotherapy integration can complement the scientist-practitioner model.

Journal of clinical psychology

Lampropoulos GK, Spengler PM, Dixon DN, Nicholas DR.
PMID: 12357439
J Clin Psychol. 2002 Oct;58(10):1227-40. doi: 10.1002/jclp.10108.

This article aims to integrate the two separate bodies of literature in Psychotherapy Integration (PI) and the Scientist-Practitioner (S-P) model. Based on an examination and synthesis of the main ideas from the two fields, it illustrates that, although developed...

Evaluation of the photodegradation of crystal violet upon light exposure by mass spectrometric and spectroscopic methods.

Journal of forensic sciences

Weyermann C, Kirsch D, Vera CC, Spengler B.
PMID: 19220655
J Forensic Sci. 2009 Mar;54(2):339-45. doi: 10.1111/j.1556-4029.2008.00975.x. Epub 2009 Feb 06.

Crystal violet is a very common dye in ballpoint ink. Recent research suggests that the degradation of triarylmethane dyes gives an indication of the age of a ballpoint pen entry on a document. The main problem for the quantitative...

Ref. Unnecessary ingredients by Edgar S. Lower.

International journal of cosmetic science

Spengler DJ.
PMID: 19250494
Int J Cosmet Sci. 1994 Jun;16(3):137. doi: 10.1111/j.1467-2494.1994.tb00091.x.

No abstract available.

Collaborating to end health disparities in our lifetime.

American journal of public health

Graham GN, Spengler RF.
PMID: 19762653
Am J Public Health. 2009 Nov;99(11):1930-2. doi: 10.2105/AJPH.2009.167908. Epub 2009 Sep 17.

No abstract available.

Evaluation of an annular denuder/filter pack system to collect acidic aerosols and gases.

Environmental science & technology

Koutrakis P, Wolfson JM, Slater JL, Brauer M, Spengler JD, Stevens RK, Stone CL.
PMID: 22200475
Environ Sci Technol. 1988 Dec 01;22(12):1463-8. doi: 10.1021/es00177a013.

No abstract available.

Increased wild-type N-ras activation by neurofibromin down-regulation increases human neuroblastoma stem cell malignancy.

Genes & cancer

Han D, Spengler BA, Ross RA.
PMID: 22737269
Genes Cancer. 2011 Nov;2(11):1034-43. doi: 10.1177/1947601912443127.

Cellular heterogeneity is a well-known feature of human neuroblastoma tumors and cell lines. Of the 3 phenotypes (N-, I-, and S-type) isolated and characterized, the I-type cancer stem cell of neuroblastoma is the most malignant. Here, we report that,...

Mirion--a software package for automatic processing of mass spectrometric images.

Journal of the American Society for Mass Spectrometry

Paschke C, Leisner A, Hester A, Maass K, Guenther S, Bouschen W, Spengler B.
PMID: 23761044
J Am Soc Mass Spectrom. 2013 Aug;24(8):1296-306. doi: 10.1007/s13361-013-0667-0. Epub 2013 Jun 13.

Mass spectrometric imaging (MSI) techniques are of growing interest for the Life Sciences. In recent years, the development of new instruments employing ion sources that are tailored for spatial scanning allowed the acquisition of large data sets. A subsequent...

Nitrogen dioxide inside and outside 137 homes and implications for ambient air quality standards and health effects research.

Environmental science & technology

Spengler JD, Duffy CP, Letz R, Tibbitts TW, Ferris BG.
PMID: 22263681
Environ Sci Technol. 1983 Mar 01;17(3):164-8. doi: 10.1021/es00109a008.

No abstract available.

Ambient-air ozonolysis of triglycerides in aged fingerprint residues.

The Analyst

Pleik S, Spengler B, Ram Bhandari D, Luhn S, Schäfer T, Urbach D, Kirsch D.
PMID: 29431747
Analyst. 2018 Feb 26;143(5):1197-1209. doi: 10.1039/c7an01506b.

In forensic science, reconstructing the timing of events occurring during a criminal offense is of great importance. In some cases, the time when particular evidence was left on a crime scene is a critical matter. The ability to estimate...

Archaeological assessment reveals Earth's early transformation through land use.

Science (New York, N.Y.)

Stephens L, Fuller D, Boivin N, Rick T, Gauthier N, Kay A, Marwick B, Armstrong CG, Barton CM, Denham T, Douglass K, Driver J, Janz L, Roberts P, Rogers JD, Thakar H, Altaweel M, Johnson AL, Sampietro Vattuone MM, Aldenderfer M, Archila S, Artioli G, Bale MT, Beach T, Borrell F, Braje T, Buckland PI, Jiménez Cano NG, Capriles JM, Diez Castillo A, Çilingiroğlu Ç, Negus Cleary M, Conolly J, Coutros PR, Covey RA, Cremaschi M, Crowther A, Der L, di Lernia S, Doershuk JF, Doolittle WE, Edwards KJ, Erlandson JM, Evans D, Fairbairn A, Faulkner P, Feinman G, Fernandes R, Fitzpatrick SM, Fyfe R, Garcea E, Goldstein S, Goodman RC, Dalpoim Guedes J, Herrmann J, Hiscock P, Hommel P, Horsburgh KA, Hritz C, Ives JW, Junno A, Kahn JG, Kaufman B, Kearns C, Kidder TR, Lanoë F, Lawrence D, Lee GA, Levin MJ, Lindskoug HB, López-Sáez JA, Macrae S, Marchant R, Marston JM, McClure S, McCoy MD, Miller AV, Morrison M, Motuzaite Matuzeviciute G, Müller J, Nayak A, Noerwidi S, Peres TM, Peterson CE, Proctor L, Randall AR, Renette S, Robbins Schug G, Ryzewski K, Saini R, Scheinsohn V, Schmidt P, Sebillaud P, Seitsonen O, Simpson IA, Sołtysiak A, Speakman RJ, Spengler RN, Steffen ML, Storozum MJ, Strickland KM, Thompson J, Thurston TL, Ulm S, Ustunkaya MC, Welker MH, West C, Williams PR, Wright DK, Wright N, Zahir M, Zerboni A, Beaudoin E, Munevar Garcia S, Powell J, Thornton A, Kaplan JO, Gaillard MJ, Klein Goldewijk K, Ellis E.
PMID: 31467217
Science. 2019 Aug 30;365(6456):897-902. doi: 10.1126/science.aax1192.

Environmentally transformative human use of land accelerated with the emergence of agriculture, but the extent, trajectory, and implications of these early changes are not well understood. An empirical global assessment of land use from 10,000 years before the present...

Showing 1 to 12 of 168 entries