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Showing 1 to 12 of 195 entries
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Educating reason: Critical thinking, informal logic, and the philosophy of education

informal education

Siegel H.
GSID: UuxIZGKRZCUJ
H Siegel - Informal Logic, 1985 - ojs.uwindsor.ca

… In general, when we say that education prepares children for adulthood, we do not mean for some specific adult role. Rather, we mean that education prepares … We guide a child's education primarily because a child cannot responsibly...

Knowing, believing, and understanding: What goals for science education?

Science education

Smith MU, Siegel H.
GSID: ukSHfhZVu5QJ
MU Smith, H Siegel - Science & Education, 2004 - Springer

… Second, we propose that the primary goal of science education should be student knowledge and understanding, which we will argue typically (but not always) involves belief and typically (but not always) guides action. In those instances where a...

Progesterone receptor membrane component 1 is phosphorylated upon progestin treatment in breast cancer cells.

Oncotarget

Willibald M, Bayer G, Stahlhut V, Poschmann G, Stühler K, Gierke B, Pawlak M, Seeger H, Mueck AO, Niederacher D, Fehm T, Neubauer H.
PMID: 29069804
Oncotarget. 2017 Aug 02;8(42):72480-72493. doi: 10.18632/oncotarget.19819. eCollection 2017 Sep 22.

Menopausal hormone therapy, using estrogen and synthetic progestins, is associated with an increased risk of developing breast cancer. The effect of progestins on breast cells is complex and not yet fully understood. In previous

In vivo inflammation imaging using a CB2R-targeted near infrared fluorescent probe.

American journal of nuclear medicine and molecular imaging

Zhang S, Shao P, Ling X, Yang L, Hou W, Thorne SH, Beaino W, Anderson CJ, Ding Y, Bai M.
PMID: 26069858
Am J Nucl Med Mol Imaging. 2015 Feb 15;5(3):246-58. eCollection 2015.

Chronic inflammation is considered as a critical cause of a host of disorders, such as cancer, rheumatoid arthritis, atherosclerosis, and neurodegenerative diseases, although the exact mechanism is yet to be explored. Imaging tools that can specifically target inflammation are...

Anomalous Metapopulation Dynamics on Scale-Free Networks.

Physical review letters

Fedotov S, Stage H.
PMID: 28306314
Phys Rev Lett. 2017 Mar 03;118(9):098301. doi: 10.1103/PhysRevLett.118.098301. Epub 2017 Mar 03.

We model transport of individuals across a heterogeneous scale-free network where a few weakly connected nodes exhibit heavy-tailed residence times. Using the empirical law of the axiom of cumulative inertia and fractional analysis, we show that "anomalous cumulative inertia"...

Alternative models of addiction.

Frontiers in psychiatry

Pickard H, Ahmed SH, Foddy B.
PMID: 25741288
Front Psychiatry. 2015 Feb 13;6:20. doi: 10.3389/fpsyt.2015.00020. eCollection 2015.

No abstract available.

New insight on a possible mechanism of progestogens in terms of breast cancer risk.

Hormone molecular biology and clinical investigation

Neubauer H, Chen R, Schneck H, Knorrp T, Templin MF, Fehm T, Cahill MA, Seeger H, Yu Q, Mueck AO.
PMID: 25961254
Horm Mol Biol Clin Investig. 2011 Apr 01;6(1):185-92. doi: 10.1515/HMBCI.2010.082.

OBJECTIVES: Progestogens influence mammary gland development and probably breast cancer tumorigenesis by regulating a broad spectrum of physiological processes. We investigated receptor membrane-initiated actions of progestogens in MCF-7 breast cancer cells overexpressing progesterone receptor membrane component 1 (PGRMC1).DESIGN: MCF-7...

Effect of drospirenone on proliferation of human benign and cancerous epithelial breast cells.

Hormone molecular biology and clinical investigation

Seeger H, Ruan X, Neubauer H, Mueck AO.
PMID: 25961257
Horm Mol Biol Clin Investig. 2011 May 01;6(2):211-4. doi: 10.1515/HMBCI.2011.008.

BACKGROUND: Proliferation of human breast epithelial cells is regulated by sex hormones. Epidemiological studies indicate that progestogen addition to estrogen therapy can increase breast cancer risk. However, it remains unclear if all progestogens react in a similar manner. Here,...

Forestry's fertile crescent: the application of biotechnology to forest trees.

Plant biotechnology journal

Campbell MM, Brunner AM, Jones HM, Strauss SH.
PMID: 17156028
Plant Biotechnol J. 2003 May;1(3):141-54. doi: 10.1046/j.1467-7652.2003.00020.x.

Relative to crop plants, the domestication of forest trees is still in its infancy. For example, the domestication of many crop plants was initiated some 10,000 years ago in the so-called 'Fertile Crescent' of the Middle East. By contrast,...

A level III sentinel lymph node in breast cancer.

World journal of surgical oncology

Bowers K, Liu Y, Ghesani N, Kim SH.
PMID: 16759381
World J Surg Oncol. 2006 Jun 07;4:31. doi: 10.1186/1477-7819-4-31.

BACKGROUND: For accurate nodal staging, all blue and radioactive lymph nodes should be sampled during the sentinel lymph node biopsy for breast cancer. We report a case of anomalous drainage in which one of the sentinel lymph nodes was...

Theranostic potential of oncolytic vaccinia virus.

Theranostics

Rojas JJ, Thorne SH.
PMID: 22509200
Theranostics. 2012;2(4):363-73. doi: 10.7150/thno.3724. Epub 2012 Apr 05.

Biological cancer therapies, such as oncolytic, or replication-selective viruses have advantages over traditional therapeutics as they can employ multiple different mechanisms to target and destroy cancers (including direct cell lysis, immune activation and vascular collapse). This has led to...

Nucleocytoplasmic shuttling of cytoskeletal proteins: molecular mechanism and biological significance.

International journal of cell biology

Kumeta M, Yoshimura SH, Hejna J, Takeyasu K.
PMID: 22229032
Int J Cell Biol. 2012;2012:494902. doi: 10.1155/2012/494902. Epub 2011 Dec 20.

Various nuclear functional complexes contain cytoskeletal proteins as regulatory subunits; for example, nuclear actin participates in transcriptional complexes, and actin-related proteins are integral to chromatin remodeling complexes. Nuclear complexes such as these are involved in both basal and adaptive...

Showing 1 to 12 of 195 entries