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Showing 1 to 12 of 313 entries
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Teaching concepts in contexts: designing a chemistry teacher course in a curriculum innovation

teaching innovation

Stolk M, Bulte A, Pilot A.
GSID: IsPON-kMe6cJ
M Stolk, A Bulte, O Jong, A Pilot - Research and the quality of Science …, 2005 - Springer

… innovation of the secondary school chemistry curriculum in the Netherlands, for which a governmental committee has proposed the implementation of teaching … (a) The use of innovative teaching materials is essential to make the general curriculum innovation goals...

Empowering teachers for designing context-based chemistry education

teaching innovation

Bulte A, Pilot A, Stolk M.
GSID: Iu_xVh7NSZEJ
M Stolk, A Bulte, O De Jong, A Pilot - Towards Research-based …, 2006 - researchgate.net

Teacher participation in designing new teaching materials is considered as an important factor for a successful curriculum innovation. However, many teachers do not feel very …

FDA Facilitated Regulatory Pathways: Visualizing Their Characteristics, Development, and Authorization Timelines.

Frontiers in pharmacology

Liberti L, Bujar M, Breckenridge A, Hoekman J, McAuslane N, Stolk P, Leufkens H.
PMID: 28420989
Front Pharmacol. 2017 Apr 03;8:161. doi: 10.3389/fphar.2017.00161. eCollection 2017.

The US Food and Drug Administration (FDA) has four facilitated regulatory pathways (FRPs): Fast Track (FT), Breakthrough Therapy (BTD), Priority Review (PR), and Accelerated Approval (AA). Only PR specifies an expedited review timeline (6 months). We sought to determine...

Functional characterisation of bone marrow-derived mesenchymal stromal cells from COPD patients.

ERJ open research

Broekman W, Roelofs H, Zarcone MC, Taube C, Stolk J, Hiemstra PS.
PMID: 27730190
ERJ Open Res. 2016 Jun 28;2(2). doi: 10.1183/23120541.00045-2015. eCollection 2016 Apr.

Autologous bone marrow-derived mesenchymal stromal cells (BM-MSCs) are evaluated for clinical use in chronic obstructive pulmonary disease (COPD) patients, but it is unclear whether COPD affects BM-MSCs. To investigate this, BM-MSCs from nine COPD patients and nine non-COPD age-matched...

Molecular diagnostics of lung cancer in the clinic.

Translational lung cancer research

Sholl L.
PMID: 29114472
Transl Lung Cancer Res. 2017 Oct;6(5):560-569. doi: 10.21037/tlcr.2017.08.03.

According to current practice guidelines, all patients with advanced non-small cell lung cancer (NSCLC) should undergo predictive biomarker testing. For squamous cell carcinoma patients, PD-L1 immunohistochemistry is indicated to select patients for immunotherapy in the first line. For lung...

School Performance and Disease Interference in Adolescents with Sickle Cell Disease.

Physical disabilities : education and related services

Crosby LE, Joffe NE, Irwin MK, Strong H, Peugh J, Shook L, Kalinyak KA, Mitchell MJ.
PMID: 27547816
Phys Disabil. 2015;34(1):14-30. doi: 10.14434/pders.v34i1.13918.

Sickle cell disease (SCD) results in neuropsychological complications that place adolescents at higher risk for limited educational achievement. A first step to developing effective educational interventions is to understand the impact of SCD on school performance. The current study...

Parameter estimation in tree graph metabolic networks.

PeerJ

Astola L, Stigter H, Gomez Roldan MV, van Eeuwijk F, Hall RD, Groenenboom M, Molenaar JJ.
PMID: 27688960
PeerJ. 2016 Sep 20;4:e2417. doi: 10.7717/peerj.2417. eCollection 2016.

We study the glycosylation processes that convert initially toxic substrates to nutritionally valuable metabolites in the flavonoid biosynthesis pathway of tomato (Solanum lycopersicum) seedlings. To estimate the reaction rates we use ordinary differential equations (ODEs) to model the enzyme...

Body image in children and adolescents: where do we go from here?.

Body image

Smolak L.
PMID: 18089138
Body Image. 2004 Jan;1(1):15-28. doi: 10.1016/S1740-1445(03)00008-1.

During the past two decades, there has been an explosion of research concerning body image in children and adolescence. This research has been fueled both by concern about the effects of poor body image in children and adolescents themselves...

Perspectives on quality of life of people with intellectual disabilities: the interpretation of discrepancies between clients and caregivers.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Janssen CG, Schuengel C, Stolk J.
PMID: 15789941
Qual Life Res. 2005 Feb;14(1):57-69. doi: 10.1007/s11136-004-1692-z.

Large discrepancies have sometimes been found between the quality of life (QOL) experienced by clients with intellectual disabilities and their QOL as described by their caregivers. Olsen and Schober (Soc Indi Res 1993; 28: 173-193) may have provided a...

Chlorido(1-cyclo-pentyl-idene-4-ethyl-thio-semicarbazidato-κN,S)diphenyl-tin(IV).

Acta crystallographica. Section E, Structure reports online

Venkatraman R, Sitole L, Fronczek FR.
PMID: 21578665
Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 21;65:m1653-4. doi: 10.1107/S1600536809047400.

The Sn atom in the title compound, [Sn(C(6)H(5))(2)(C(8)H(14)N(3)S)Cl], is penta-coordinated with a trigonal-bipyramidal coordination geometry. The 1-cyclo-pentyl-idene-4-ethyl-thio-semicarbazidate (cpetsc) ligand coordinates through the S atom and the N atom bonds to the cyclo-pentyl group, forming a five-membered ring with the...

The effect of additional dead space on respiratory exchange ratio and carbon dioxide production due to training.

Journal of sports science & medicine

Smolka L, Borkowski J, Zaton M.
PMID: 24570603
J Sports Sci Med. 2014 Jan 20;13(1):36-43. eCollection 2014 Jan.

The purpose of the study was to investigate the effects of implementing additional respiratory dead space during cycloergometry-based aerobic training. The primary outcome measures were respiratory exchange ratio (RER) and carbon dioxide production (VCO2). Two groups of young healthy...

Measuring the incidence and reporting of violence against women and girls in liberia using the 'neighborhood method'.

Conflict and health

Stark L, Warner A, Lehmann H, Boothby N, Ager A.
PMID: 24059598
Confl Health. 2013 Sep 23;7(1):20. doi: 10.1186/1752-1505-7-20.

BACKGROUND: This paper reports on the use of a "neighborhood method" to measure the nature and incidence of violence against women and girls in post-conflict Liberia.METHODS: The study population comprised females in Montserrado and Nimba counties. Study participants were...

Showing 1 to 12 of 313 entries