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Germline whole exome sequencing and large-scale replication identifies .

Oncotarget

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.
PMID: 28881617
Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01.

We analyzed whole exome sequencing data in germline DNA from 412 high grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas Project and identified 5,517 genes harboring a predicted deleterious germline coding mutation in at least one...

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Dicks E, Song H, Ramus SJ, et al. Germline whole exome sequencing and large-scale replication identifies . Oncotarget. 2017;8(31):50930-50940doi: 10.18632/oncotarget.15871.
Dicks, E., Song, H., Ramus, S. J., Oudenhove, E. V., Tyrer, J. P., Intermaggio, M. P., Kar, S., Harrington, P., Bowtell, D. D., Group, A. S., Cicek, M. S., Cunningham, J. M., Fridley, B. L., Alsop, J., Jimenez-Linan, M., Piskorz, A., Goranova, T., Kent, E., Siddiqui, N., Paul, J., Crawford, R., Poblete, S., Lele, S., Sucheston-Campbell, L., Moysich, K. B., Sieh, W., McGuire, V., Lester, J., Odunsi, K., Whittemore, A. S., Bogdanova, N., Dürst, M., Hillemanns, P., Karlan, B. Y., Gentry-Maharaj, A., Menon, U., Tischkowitz, M., Levine, D., Brenton, J. D., Dörk, T., Goode, E. L., Gayther, S. A., & Pharoah, D. P. P. (2017). Germline whole exome sequencing and large-scale replication identifies . Oncotarget, 8(31), 50930-50940. https://doi.org/10.18632/oncotarget.15871
Dicks, Ed, et al. "Germline whole exome sequencing and large-scale replication identifies ." Oncotarget vol. 8,31 (2017): 50930-50940. doi: https://doi.org/10.18632/oncotarget.15871
Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP. Germline whole exome sequencing and large-scale replication identifies . Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01. PMID: 28881617; PMCID: PMC5584218.
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Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

Journal of genetics and genome research

Jim HS, Lin HY, Tyrer JP, Lawrenson K, Dennis J, Chornokur G, Chen Z, Chen AY, Permuth-Wey J, Aben KK, Anton-Culver H, Antonenkova N, Bruinsma F, Bandera EV, Bean YT, Beckmann MW, Bisogna M, Bjorge L, Bogdanova N, Brinton LA, Brooks-Wilson A, Bunker CH, Butzow R, Campbell IG, Carty K, Chang-Claude J, Cook LS, Cramer DW, Cunningham JM, Cybulski C, Dansonka-Mieszkowska A, du Bois A, Despierre E, Sieh W, Doherty JA, Dörk T, Dürst M, Easton DF, Eccles DM, Edwards RP, Ekici AB, Fasching PA, Fridley BL, Gao YT, Gentry-Maharaj A, Giles GG, Glasspool R, Goodman MT, Gronwald J, Harter P, Hasmad HN, Hein A, Heitz F, Hildebrandt MA, Hillemanns P, Hogdall CK, Hogdall E, Hosono S, Iversen ES, Jakubowska A, Jensen A, Ji BT, Karlan BY, Kellar M, Kiemeney LA, Krakstad C, Kjaer SK, Kupryjanczyk J, Vierkant RA, Lambrechts D, Lambrechts S, Le ND, Lee AW, Lele S, Leminen A, Lester J, Levine DA, Liang D, Lim BK, Lissowska J, Lu K, Lubinski J, Lundvall L, Massuger LF, Matsuo K, McGuire V, McLaughlin JR, McNeish I, Menon U, Milne RL, Modugno F, Thomsen L, Moysich KB, Ness RB, Nevanlinna H, Eilber U, Odunsi K, Olson SH, Orlow I, Orsulic S, Palmieri Weber R, Paul J, Pearce CL, Pejovic T, Pelttari LM, Pike MC, Poole EM, Schernhammer E, Risch HA, Rosen B, Rossing MA, Rothstein JH, Rudolph A, Runnebaum IB, Rzepecka IK, Salvesen HB, Schwaab I, Shu XO, Shvetsov YB, Siddiqui N, Song H, Southey MC, Spiewankiewicz B, Sucheston-Campbell L, Teo SH, Terry KL, Thompson PJ, Tangen IL, Tworoger SS, van Altena AM, Vergote I, Walsh CS, Wang-Gohrke S, Wentzensen N, Whittemore AS, Wicklund KG, Wilkens LR, Wu AH, Wu X, Woo YL, Yang H, Zheng W, Ziogas A, Amankwah E, Berchuck A, Schildkraut JM, Kelemen LE, Ramus SJ, Monteiro AN, Goode EL, Narod SA, Gayther SA, Pharoah PD, Sellers TA, Phelan CM.
PMID: 26807442
J Genet Genome Res. 2015;2(2). doi: 10.23937/2378-3648/1410017. Epub 2015 Sep 15.

Disruption in circadian gene expression, whether due to genetic variation or environmental factors (e.g., light at night, shiftwork), is associated with increased incidence of breast, prostate, gastrointestinal and hematologic cancers and gliomas. Circadian genes are highly expressed in the...

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Jim HS, Lin HY, Tyrer JP, et al. Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC). J Genet Genome Res. 2015;2(2)doi: 10.23937/2378-3648/1410017.
Jim, H. S., Lin, H. Y., Tyrer, J. P., Lawrenson, K., Dennis, J., Chornokur, G., Chen, Z., Chen, A. Y., Permuth-Wey, J., Aben, K. K., Anton-Culver, H., Antonenkova, N., Bruinsma, F., Bandera, E. V., Bean, Y. T., Beckmann, M. W., Bisogna, M., Bjorge, L., Bogdanova, N., Brinton, L. A., Brooks-Wilson, A., Bunker, C. H., Butzow, R., Campbell, I. G., Carty, K., Chang-Claude, J., Cook, L. S., Cramer, D. W., Cunningham, J. M., Cybulski, C., Dansonka-Mieszkowska, A., du Bois, A., Despierre, E., Sieh, W., Doherty, J. A., Dörk, T., Dürst, M., Easton, D. F., Eccles, D. M., Edwards, R. P., Ekici, A. B., Fasching, P. A., Fridley, B. L., Gao, Y. T., Gentry-Maharaj, A., Giles, G. G., Glasspool, R., Goodman, M. T., Gronwald, J., Harter, P., Hasmad, H. N., Hein, A., Heitz, F., Hildebrandt, M. A., Hillemanns, P., Hogdall, C. K., Hogdall, E., Hosono, S., Iversen, E. S., Jakubowska, A., Jensen, A., Ji, B. T., Karlan, B. Y., Kellar, M., Kiemeney, L. A., Krakstad, C., Kjaer, S. K., Kupryjanczyk, J., Vierkant, R. A., Lambrechts, D., Lambrechts, S., Le, N. D., Lee, A. W., Lele, S., Leminen, A., Lester, J., Levine, D. A., Liang, D., Lim, B. K., Lissowska, J., Lu, K., Lubinski, J., Lundvall, L., Massuger, L. F., Matsuo, K., McGuire, V., McLaughlin, J. R., McNeish, I., Menon, U., Milne, R. L., Modugno, F., Thomsen, L., Moysich, K. B., Ness, R. B., Nevanlinna, H., Eilber, U., Odunsi, K., Olson, S. H., Orlow, I., Orsulic, S., Palmieri Weber, R., Paul, J., Pearce, C. L., Pejovic, T., Pelttari, L. M., Pike, M. C., Poole, E. M., Schernhammer, E., Risch, H. A., Rosen, B., Rossing, M. A., Rothstein, J. H., Rudolph, A., Runnebaum, I. B., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Shu, X. O., Shvetsov, Y. B., Siddiqui, N., Song, H., Southey, M. C., Spiewankiewicz, B., Sucheston-Campbell, L., Teo, S. H., Terry, K. L., Thompson, P. J., Tangen, I. L., Tworoger, S. S., van Altena, A. M., Vergote, I., Walsh, C. S., Wang-Gohrke, S., Wentzensen, N., Whittemore, A. S., Wicklund, K. G., Wilkens, L. R., Wu, A. H., Wu, X., Woo, Y. L., Yang, H., Zheng, W., Ziogas, A., Amankwah, E., Berchuck, A., Schildkraut, J. M., Kelemen, L. E., Ramus, S. J., Monteiro, A. N., Goode, E. L., Narod, S. A., Gayther, S. A., Pharoah, P. D., Sellers, T. A., & Phelan, C. M. (2015). Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC). Journal of genetics and genome research, 2(2), . https://doi.org/10.23937/2378-3648/1410017
Jim, Heather S L, et al. "Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC)." Journal of genetics and genome research vol. 2,2 (2015). doi: https://doi.org/10.23937/2378-3648/1410017
Jim HS, Lin HY, Tyrer JP, Lawrenson K, Dennis J, Chornokur G, Chen Z, Chen AY, Permuth-Wey J, Aben KK, Anton-Culver H, Antonenkova N, Bruinsma F, Bandera EV, Bean YT, Beckmann MW, Bisogna M, Bjorge L, Bogdanova N, Brinton LA, Brooks-Wilson A, Bunker CH, Butzow R, Campbell IG, Carty K, Chang-Claude J, Cook LS, Cramer DW, Cunningham JM, Cybulski C, Dansonka-Mieszkowska A, du Bois A, Despierre E, Sieh W, Doherty JA, Dörk T, Dürst M, Easton DF, Eccles DM, Edwards RP, Ekici AB, Fasching PA, Fridley BL, Gao YT, Gentry-Maharaj A, Giles GG, Glasspool R, Goodman MT, Gronwald J, Harter P, Hasmad HN, Hein A, Heitz F, Hildebrandt MA, Hillemanns P, Hogdall CK, Hogdall E, Hosono S, Iversen ES, Jakubowska A, Jensen A, Ji BT, Karlan BY, Kellar M, Kiemeney LA, Krakstad C, Kjaer SK, Kupryjanczyk J, Vierkant RA, Lambrechts D, Lambrechts S, Le ND, Lee AW, Lele S, Leminen A, Lester J, Levine DA, Liang D, Lim BK, Lissowska J, Lu K, Lubinski J, Lundvall L, Massuger LF, Matsuo K, McGuire V, McLaughlin JR, McNeish I, Menon U, Milne RL, Modugno F, Thomsen L, Moysich KB, Ness RB, Nevanlinna H, Eilber U, Odunsi K, Olson SH, Orlow I, Orsulic S, Palmieri Weber R, Paul J, Pearce CL, Pejovic T, Pelttari LM, Pike MC, Poole EM, Schernhammer E, Risch HA, Rosen B, Rossing MA, Rothstein JH, Rudolph A, Runnebaum IB, Rzepecka IK, Salvesen HB, Schwaab I, Shu XO, Shvetsov YB, Siddiqui N, Song H, Southey MC, Spiewankiewicz B, Sucheston-Campbell L, Teo SH, Terry KL, Thompson PJ, Tangen IL, Tworoger SS, van Altena AM, Vergote I, Walsh CS, Wang-Gohrke S, Wentzensen N, Whittemore AS, Wicklund KG, Wilkens LR, Wu AH, Wu X, Woo YL, Yang H, Zheng W, Ziogas A, Amankwah E, Berchuck A, Schildkraut JM, Kelemen LE, Ramus SJ, Monteiro AN, Goode EL, Narod SA, Gayther SA, Pharoah PD, Sellers TA, Phelan CM. Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC). J Genet Genome Res. 2015;2(2). doi: 10.23937/2378-3648/1410017. Epub 2015 Sep 15. PMID: 26807442; PMCID: PMC4722961.
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Genome-Wide Association Analyses Identify Variants in .

Frontiers in genetics

Wang J, Clay-Gilmour AI, Karaesmen E, Rizvi A, Zhu Q, Yan L, Preus L, Liu S, Wang Y, Griffiths E, Stram DO, Pooler L, Sheng X, Haiman C, Van Den Berg D, Webb A, Brock G, Spellman S, Pasquini M, McCarthy P, Allan J, Stölzel F, Onel K, Hahn T, Sucheston-Campbell LE.
PMID: 34220922
Front Genet. 2021 Jun 17;12:554948. doi: 10.3389/fgene.2021.554948. eCollection 2021.

The role of common genetic variation in susceptibility to acute myeloid leukemia (AML), and myelodysplastic syndrome (MDS), a group of rare clonal hematologic disorders characterized by dysplastic hematopoiesis and high mortality, remains unclear. We performed AML and MDS genome-wide...

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Wang J, Clay-Gilmour AI, Karaesmen E, et al. Genome-Wide Association Analyses Identify Variants in . Front Genet. 2021;12:554948doi: 10.3389/fgene.2021.554948.
Wang, J., Clay-Gilmour, A. I., Karaesmen, E., Rizvi, A., Zhu, Q., Yan, L., Preus, L., Liu, S., Wang, Y., Griffiths, E., Stram, D. O., Pooler, L., Sheng, X., Haiman, C., Van Den Berg, D., Webb, A., Brock, G., Spellman, S., Pasquini, M., McCarthy, P., Allan, J., Stölzel, F., Onel, K., Hahn, T., & Sucheston-Campbell, L. E. (2021). Genome-Wide Association Analyses Identify Variants in . Frontiers in genetics, 12554948. https://doi.org/10.3389/fgene.2021.554948
Wang, Junke, et al. "Genome-Wide Association Analyses Identify Variants in ." Frontiers in genetics vol. 12 (2021): 554948. doi: https://doi.org/10.3389/fgene.2021.554948
Wang J, Clay-Gilmour AI, Karaesmen E, Rizvi A, Zhu Q, Yan L, Preus L, Liu S, Wang Y, Griffiths E, Stram DO, Pooler L, Sheng X, Haiman C, Van Den Berg D, Webb A, Brock G, Spellman S, Pasquini M, McCarthy P, Allan J, Stölzel F, Onel K, Hahn T, Sucheston-Campbell LE. Genome-Wide Association Analyses Identify Variants in . Front Genet. 2021 Jun 17;12:554948. doi: 10.3389/fgene.2021.554948. eCollection 2021. PMID: 34220922; PMCID: PMC8248805.
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Higher than expected frequencies of non-ovarian cancers within a large familial ovarian cancer registry.

American journal of clinical and experimental obstetrics and gynecology

Brightwell RM, Grzankowski KS, Kaur J, Poblete S, Miller A, Lele SB, Sucheston-Campbell L, Moysich K, Odunsi KO.
PMID: 26605374
Am J Clin Exp Obstet Gynecol. 2015;2(1):39-44. Epub 2015 Feb 15.

Our objective was to determine whether the frequencies of non-ovarian cancers (NOC) within families in a large Familial Ovarian Cancer Registry (FOCR) are significantly different from the frequencies listed in the SEER database. The FOCR was established in 1981....

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Brightwell RM, Grzankowski KS, Kaur J, et al. Higher than expected frequencies of non-ovarian cancers within a large familial ovarian cancer registry. Am J Clin Exp Obstet Gynecol. 2015;2(1):39-44
Brightwell, R. M., Grzankowski, K. S., Kaur, J., Poblete, S., Miller, A., Lele, S. B., Sucheston-Campbell, L., Moysich, K., & Odunsi, K. O. (2015). Higher than expected frequencies of non-ovarian cancers within a large familial ovarian cancer registry. American journal of clinical and experimental obstetrics and gynecology, 2(1), 39-44.
Brightwell, Rachel M, et al. "Higher than expected frequencies of non-ovarian cancers within a large familial ovarian cancer registry." American journal of clinical and experimental obstetrics and gynecology vol. 2,1 (2015): 39-44.
Brightwell RM, Grzankowski KS, Kaur J, Poblete S, Miller A, Lele SB, Sucheston-Campbell L, Moysich K, Odunsi KO. Higher than expected frequencies of non-ovarian cancers within a large familial ovarian cancer registry. Am J Clin Exp Obstet Gynecol. 2015;2(1):39-44. Epub 2015 Feb 15. PMID: 26605374; PMCID: PMC4655182.
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Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes.

Frontiers in genetics

Ruiz-Narváez EA, Sucheston-Campbell L, Bensen JT, Yao S, Haddad S, Haiman CA, Bandera EV, John EM, Bernstein L, Hu JJ, Ziegler RG, Deming SL, Olshan AF, Ambrosone CB, Palmer JR, Lunetta KL.
PMID: 27708667
Front Genet. 2016 Sep 21;7:170. doi: 10.3389/fgene.2016.00170. eCollection 2016.

Recent genetic admixture coupled with striking differences in incidence of estrogen receptor (ER) breast cancer subtypes, as well as severity, between women of African and European ancestry, provides an excellent rationale for performing admixture mapping in African American women...

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Ruiz-Narváez EA, Sucheston-Campbell L, Bensen JT, et al. Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes. Front Genet. 2016;7:170doi: 10.3389/fgene.2016.00170.
Ruiz-Narváez, E. A., Sucheston-Campbell, L., Bensen, J. T., Yao, S., Haddad, S., Haiman, C. A., Bandera, E. V., John, E. M., Bernstein, L., Hu, J. J., Ziegler, R. G., Deming, S. L., Olshan, A. F., Ambrosone, C. B., Palmer, J. R., & Lunetta, K. L. (2016). Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes. Frontiers in genetics, 7170. https://doi.org/10.3389/fgene.2016.00170
Ruiz-Narváez, Edward A, et al. "Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes." Frontiers in genetics vol. 7 (2016): 170. doi: https://doi.org/10.3389/fgene.2016.00170
Ruiz-Narváez EA, Sucheston-Campbell L, Bensen JT, Yao S, Haddad S, Haiman CA, Bandera EV, John EM, Bernstein L, Hu JJ, Ziegler RG, Deming SL, Olshan AF, Ambrosone CB, Palmer JR, Lunetta KL. Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes. Front Genet. 2016 Sep 21;7:170. doi: 10.3389/fgene.2016.00170. eCollection 2016. PMID: 27708667; PMCID: PMC5030764.
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Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.

Nature communications

Lin WY, Fordham SE, Hungate E, Sunter NJ, Elstob C, Xu Y, Park C, Quante A, Strauch K, Gieger C, Skol A, Rahman T, Sucheston-Campbell L, Wang J, Hahn T, Clay-Gilmour AI, Jones GL, Marr HJ, Jackson GH, Menne T, Collin M, Ivey A, Hills RK, Burnett AK, Russell NH, Fitzgibbon J, Larson RA, Le Beau MM, Stock W, Heidenreich O, Alharbi A, Allsup DJ, Houlston RS, Norden J, Dickinson AM, Douglas E, Lendrem C, Daly AK, Palm L, Piechocki K, Jeffries S, Bornhäuser M, Röllig C, Altmann H, Ruhnke L, Kunadt D, Wagenführ L, Cordell HJ, Darlay R, Andersen MK, Fontana MC, Martinelli G, Marconi G, Sanz MA, Cervera J, Gómez-Seguí I, Cluzeau T, Moreilhon C, Raynaud S, Sill H, Voso MT, Lo-Coco F, Dombret H, Cheok M, Preudhomme C, Gale RE, Linch D, Gaal-Wesinger J, Masszi A, Nowak D, Hofmann WK, Gilkes A, Porkka K, Milosevic Feenstra JD, Kralovics R, Grimwade D, Meggendorfer M, Haferlach T, Krizsán S, Bödör C, Stölzel F, Onel K, Allan JM.
PMID: 34983928
Nat Commun. 2022 Jan 04;13(1):2. doi: 10.1038/s41467-021-27679-6.

No abstract available.

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Lin WY, Fordham SE, Hungate E, et al. Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. Nat Commun. 2022;13(1):2doi: 10.1038/s41467-021-27679-6.
Lin, W. Y., Fordham, S. E., Hungate, E., Sunter, N. J., Elstob, C., Xu, Y., Park, C., Quante, A., Strauch, K., Gieger, C., Skol, A., Rahman, T., Sucheston-Campbell, L., Wang, J., Hahn, T., Clay-Gilmour, A. I., Jones, G. L., Marr, H. J., Jackson, G. H., Menne, T., Collin, M., Ivey, A., Hills, R. K., Burnett, A. K., Russell, N. H., Fitzgibbon, J., Larson, R. A., Le Beau, M. M., Stock, W., Heidenreich, O., Alharbi, A., Allsup, D. J., Houlston, R. S., Norden, J., Dickinson, A. M., Douglas, E., Lendrem, C., Daly, A. K., Palm, L., Piechocki, K., Jeffries, S., Bornhäuser, M., Röllig, C., Altmann, H., Ruhnke, L., Kunadt, D., Wagenführ, L., Cordell, H. J., Darlay, R., Andersen, M. K., Fontana, M. C., Martinelli, G., Marconi, G., Sanz, M. A., Cervera, J., Gómez-Seguí, I., Cluzeau, T., Moreilhon, C., Raynaud, S., Sill, H., Voso, M. T., Lo-Coco, F., Dombret, H., Cheok, M., Preudhomme, C., Gale, R. E., Linch, D., Gaal-Wesinger, J., Masszi, A., Nowak, D., Hofmann, W. K., Gilkes, A., Porkka, K., Milosevic Feenstra, J. D., Kralovics, R., Grimwade, D., Meggendorfer, M., Haferlach, T., Krizsán, S., Bödör, C., Stölzel, F., Onel, K., & Allan, J. M. (2022). Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. Nature communications, 13(1), 2. https://doi.org/10.1038/s41467-021-27679-6
Lin, Wei-Yu, et al. "Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia." Nature communications vol. 13,1 (2022): 2. doi: https://doi.org/10.1038/s41467-021-27679-6
Lin WY, Fordham SE, Hungate E, Sunter NJ, Elstob C, Xu Y, Park C, Quante A, Strauch K, Gieger C, Skol A, Rahman T, Sucheston-Campbell L, Wang J, Hahn T, Clay-Gilmour AI, Jones GL, Marr HJ, Jackson GH, Menne T, Collin M, Ivey A, Hills RK, Burnett AK, Russell NH, Fitzgibbon J, Larson RA, Le Beau MM, Stock W, Heidenreich O, Alharbi A, Allsup DJ, Houlston RS, Norden J, Dickinson AM, Douglas E, Lendrem C, Daly AK, Palm L, Piechocki K, Jeffries S, Bornhäuser M, Röllig C, Altmann H, Ruhnke L, Kunadt D, Wagenführ L, Cordell HJ, Darlay R, Andersen MK, Fontana MC, Martinelli G, Marconi G, Sanz MA, Cervera J, Gómez-Seguí I, Cluzeau T, Moreilhon C, Raynaud S, Sill H, Voso MT, Lo-Coco F, Dombret H, Cheok M, Preudhomme C, Gale RE, Linch D, Gaal-Wesinger J, Masszi A, Nowak D, Hofmann WK, Gilkes A, Porkka K, Milosevic Feenstra JD, Kralovics R, Grimwade D, Meggendorfer M, Haferlach T, Krizsán S, Bödör C, Stölzel F, Onel K, Allan JM. Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. Nat Commun. 2022 Jan 04;13(1):2. doi: 10.1038/s41467-021-27679-6. PMID: 34983928.
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Aging Phenotypes and Restoring Functional Deficits in Older Adults With Hematologic Malignancy.

Journal of the National Comprehensive Cancer Network : JNCCN

Rosko AE, Wall S, Baiocchi R, Benson DM, Brammer JE, Byrd JC, Efebera YA, Maddocks K, Rogers KA, Jones D, Sucheston-Campbell L, Tang H, Ozer HG, Huang Y, Burd CE, Naughton MJ.
PMID: 33770752
J Natl Compr Canc Netw. 2021 Mar 26;19(9):1027-1036. doi: 10.6004/jnccn.2020.7686.

BACKGROUND: Gauging fitness remains a challenge among older adults with hematologic malignancies, and interventions to restore function are lacking. We pilot a structured exercise intervention and novel biologic correlates of aging using epigenetic clocks and markers of immunosenescence to...

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Rosko AE, Wall S, Baiocchi R, et al. Aging Phenotypes and Restoring Functional Deficits in Older Adults With Hematologic Malignancy. J Natl Compr Canc Netw. 2021;19(9):1027-1036doi: 10.6004/jnccn.2020.7686.
Rosko, A. E., Wall, S., Baiocchi, R., Benson, D. M., Brammer, J. E., Byrd, J. C., Efebera, Y. A., Maddocks, K., Rogers, K. A., Jones, D., Sucheston-Campbell, L., Tang, H., Ozer, H. G., Huang, Y., Burd, C. E., & Naughton, M. J. (2021). Aging Phenotypes and Restoring Functional Deficits in Older Adults With Hematologic Malignancy. Journal of the National Comprehensive Cancer Network : JNCCN, 19(9), 1027-1036. https://doi.org/10.6004/jnccn.2020.7686
Rosko, Ashley E, et al. "Aging Phenotypes and Restoring Functional Deficits in Older Adults With Hematologic Malignancy." Journal of the National Comprehensive Cancer Network : JNCCN vol. 19,9 (2021): 1027-1036. doi: https://doi.org/10.6004/jnccn.2020.7686
Rosko AE, Wall S, Baiocchi R, Benson DM, Brammer JE, Byrd JC, Efebera YA, Maddocks K, Rogers KA, Jones D, Sucheston-Campbell L, Tang H, Ozer HG, Huang Y, Burd CE, Naughton MJ. Aging Phenotypes and Restoring Functional Deficits in Older Adults With Hematologic Malignancy. J Natl Compr Canc Netw. 2021 Mar 26;19(9):1027-1036. doi: 10.6004/jnccn.2020.7686. PMID: 33770752; PMCID: PMC8600896.
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Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry.

Journal of the National Cancer Institute

Du Z, Gao G, Adedokun B, Ahearn T, Lunetta KL, Zirpoli G, Troester MA, Ruiz-Narváez EA, Haddad SA, PalChoudhury P, Figueroa J, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Mancuso N, Press MF, Deming SL, Rodriguez-Gil JL, Yao S, Ogundiran TO, Ojengbe O, Bolla MK, Dennis J, Dunning AM, Easton DF, Michailidou K, Pharoah PDP, Sandler DP, Taylor JA, Wang Q, Weinberg CR, Kitahara CM, Blot W, Nathanson KL, Hennis A, Nemesure B, Ambs S, Sucheston-Campbell LE, Bensen JT, Chanock SJ, Olshan AF, Ambrosone CB, Olopade OI, Yarney J, Awuah B, Wiafe-Addai B, Conti DV, Palmer JR, Garcia-Closas M, Huo D, Haiman CA.
PMID: 33769540
J Natl Cancer Inst. 2021 Sep 04;113(9):1168-1176. doi: 10.1093/jnci/djab050.

BACKGROUND: Polygenic risk scores (PRSs) have been demonstrated to identify women of European, Asian, and Latino ancestry at elevated risk of developing breast cancer (BC). We evaluated the performance of existing PRSs trained in European ancestry populations among women...

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Du Z, Gao G, Adedokun B, et al. Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. J Natl Cancer Inst. 2021;113(9):1168-1176doi: 10.1093/jnci/djab050.
Du, Z., Gao, G., Adedokun, B., Ahearn, T., Lunetta, K. L., Zirpoli, G., Troester, M. A., Ruiz-Narváez, E. A., Haddad, S. A., PalChoudhury, P., Figueroa, J., John, E. M., Bernstein, L., Zheng, W., Hu, J. J., Ziegler, R. G., Nyante, S., Bandera, E. V., Ingles, S. A., Mancuso, N., Press, M. F., Deming, S. L., Rodriguez-Gil, J. L., Yao, S., Ogundiran, T. O., Ojengbe, O., Bolla, M. K., Dennis, J., Dunning, A. M., Easton, D. F., Michailidou, K., Pharoah, P. D. P., Sandler, D. P., Taylor, J. A., Wang, Q., Weinberg, C. R., Kitahara, C. M., Blot, W., Nathanson, K. L., Hennis, A., Nemesure, B., Ambs, S., Sucheston-Campbell, L. E., Bensen, J. T., Chanock, S. J., Olshan, A. F., Ambrosone, C. B., Olopade, O. I., Yarney, J., Awuah, B., Wiafe-Addai, B., Conti, D. V., Palmer, J. R., Garcia-Closas, M., Huo, D., & Haiman, C. A. (2021). Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. Journal of the National Cancer Institute, 113(9), 1168-1176. https://doi.org/10.1093/jnci/djab050
Du, Zhaohui, et al. "Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry." Journal of the National Cancer Institute vol. 113,9 (2021): 1168-1176. doi: https://doi.org/10.1093/jnci/djab050
Du Z, Gao G, Adedokun B, Ahearn T, Lunetta KL, Zirpoli G, Troester MA, Ruiz-Narváez EA, Haddad SA, PalChoudhury P, Figueroa J, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Mancuso N, Press MF, Deming SL, Rodriguez-Gil JL, Yao S, Ogundiran TO, Ojengbe O, Bolla MK, Dennis J, Dunning AM, Easton DF, Michailidou K, Pharoah PDP, Sandler DP, Taylor JA, Wang Q, Weinberg CR, Kitahara CM, Blot W, Nathanson KL, Hennis A, Nemesure B, Ambs S, Sucheston-Campbell LE, Bensen JT, Chanock SJ, Olshan AF, Ambrosone CB, Olopade OI, Yarney J, Awuah B, Wiafe-Addai B, Conti DV, Palmer JR, Garcia-Closas M, Huo D, Haiman CA. Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. J Natl Cancer Inst. 2021 Sep 04;113(9):1168-1176. doi: 10.1093/jnci/djab050. PMID: 33769540; PMCID: PMC8418423.
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Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation.

EClinicalMedicine

Hahn T, Wang J, Preus LM, Karaesmen E, Rizvi A, Clay-Gilmour AI, Zhu Q, Wang Y, Yan L, Liu S, Stram DO, Pooler L, Sheng X, Haiman CA, Berg DVD, Webb A, Brock G, Spellman SR, Onel K, McCarthy PL, Pasquini MC, Sucheston-Campbell LE.
PMID: 34746714
EClinicalMedicine. 2021 Aug 25;40:101093. doi: 10.1016/j.eclinm.2021.101093. eCollection 2021 Oct.

BACKGROUND: Identification of non-human leukocyte antigen (HLA) genetic risk factors could improve survival after allogeneic blood or marrow transplant (BMT) through matching at additional loci or individualizing risk prediction. We hypothesized that non-HLA loci contributed significantly to 1-year overall...

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Hahn T, Wang J, Preus LM, et al. Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation. EClinicalMedicine. 2021;40:101093doi: 10.1016/j.eclinm.2021.101093.
Hahn, T., Wang, J., Preus, L. M., Karaesmen, E., Rizvi, A., Clay-Gilmour, A. I., Zhu, Q., Wang, Y., Yan, L., Liu, S., Stram, D. O., Pooler, L., Sheng, X., Haiman, C. A., Berg, D. V. D., Webb, A., Brock, G., Spellman, S. R., Onel, K., McCarthy, P. L., Pasquini, M. C., & Sucheston-Campbell, L. E. (2021). Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation. EClinicalMedicine, 40101093. https://doi.org/10.1016/j.eclinm.2021.101093
Hahn, Theresa, et al. "Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation." EClinicalMedicine vol. 40 (2021): 101093. doi: https://doi.org/10.1016/j.eclinm.2021.101093
Hahn T, Wang J, Preus LM, Karaesmen E, Rizvi A, Clay-Gilmour AI, Zhu Q, Wang Y, Yan L, Liu S, Stram DO, Pooler L, Sheng X, Haiman CA, Berg DVD, Webb A, Brock G, Spellman SR, Onel K, McCarthy PL, Pasquini MC, Sucheston-Campbell LE. Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation. EClinicalMedicine. 2021 Aug 25;40:101093. doi: 10.1016/j.eclinm.2021.101093. eCollection 2021 Oct. PMID: 34746714; PMCID: PMC8548922.
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Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex.

Blood advances

Clay-Gilmour AI, Hahn T, Preus LM, Onel K, Skol A, Hungate E, Zhu Q, Haiman CA, Stram DO, Pooler L, Sheng X, Yan L, Liu Q, Hu Q, Liu S, Battaglia S, Zhu X, Block AW, Sait SNJ, Karaesmen E, Rizvi A, Weisdorf DJ, Ambrosone CB, Tritchler D, Ellinghaus E, Ellinghaus D, Stanulla M, Clavel J, Orsi L, Spellman S, Pasquini MC, McCarthy PL, Sucheston-Campbell LE.
PMID: 29296818
Blood Adv. 2017 Sep 08;1(20):1717-1728. doi: 10.1182/bloodadvances.2017006023. eCollection 2017 Sep 12.

The incidence and mortality rates of B-cell acute lymphoblastic leukemia (B-ALL) differ by age and sex. To determine if inherited genetic susceptibility contributes to these differences we performed 2 genome-wide association studies (GWAS) by age, sex, and subtype and...

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Clay-Gilmour AI, Hahn T, Preus LM, et al. Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. Blood Adv. 2017;1(20):1717-1728doi: 10.1182/bloodadvances.2017006023.
Clay-Gilmour, A. I., Hahn, T., Preus, L. M., Onel, K., Skol, A., Hungate, E., Zhu, Q., Haiman, C. A., Stram, D. O., Pooler, L., Sheng, X., Yan, L., Liu, Q., Hu, Q., Liu, S., Battaglia, S., Zhu, X., Block, A. W., Sait, S. N. J., Karaesmen, E., Rizvi, A., Weisdorf, D. J., Ambrosone, C. B., Tritchler, D., Ellinghaus, E., Ellinghaus, D., Stanulla, M., Clavel, J., Orsi, L., Spellman, S., Pasquini, M. C., McCarthy, P. L., & Sucheston-Campbell, L. E. (2017). Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. Blood advances, 1(20), 1717-1728. https://doi.org/10.1182/bloodadvances.2017006023
Clay-Gilmour, Alyssa I, et al. "Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex." Blood advances vol. 1,20 (2017): 1717-1728. doi: https://doi.org/10.1182/bloodadvances.2017006023
Clay-Gilmour AI, Hahn T, Preus LM, Onel K, Skol A, Hungate E, Zhu Q, Haiman CA, Stram DO, Pooler L, Sheng X, Yan L, Liu Q, Hu Q, Liu S, Battaglia S, Zhu X, Block AW, Sait SNJ, Karaesmen E, Rizvi A, Weisdorf DJ, Ambrosone CB, Tritchler D, Ellinghaus E, Ellinghaus D, Stanulla M, Clavel J, Orsi L, Spellman S, Pasquini MC, McCarthy PL, Sucheston-Campbell LE. Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. Blood Adv. 2017 Sep 08;1(20):1717-1728. doi: 10.1182/bloodadvances.2017006023. eCollection 2017 Sep 12. PMID: 29296818; PMCID: PMC5728332.
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