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Showing 1 to 12 of 35 entries
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Spinal Hyper-Excitability and Altered Muscle Structure Contribute to Muscle Hypertonia in Newborns After Antenatal Hypoxia-Ischemia in a Rabbit Cerebral Palsy Model.

Frontiers in neurology

Synowiec S, Lu J, Yu L, Goussakov I, Lieber R, Drobyshevsky A.
PMID: 30705663
Front Neurol. 2019 Jan 17;9:1183. doi: 10.3389/fneur.2018.01183. eCollection 2018.

Rabbit kits after global antenatal hypoxic-ischemic injury exhibit motor deficits similar to humans with cerebral palsy. We tested several mechanisms previously implicated in spinal hyper-excitability after perinatal brain injury that may explain muscle hypertonia in newborns. Stiffness of hind...

Criteria to assess potential reverse innovations: opportunities for shared learning between high- and low-income countries.

Globalization and health

Bhattacharyya O, Wu D, Mossman K, Hayden L, Gill P, Cheng YL, Daar A, Soman D, Synowiec C, Taylor A, Wong J, von Zedtwitz M, Zlotkin S, Mitchell W, McGahan A.
PMID: 28122623
Global Health. 2017 Jan 25;13(1):4. doi: 10.1186/s12992-016-0225-1.

BACKGROUND: Low- and middle-income countries (LMICs) are developing novel approaches to healthcare that may be relevant to high-income countries (HICs). These include products, services, organizational processes, or policies that improve access, cost, or efficiency of healthcare. However, given the...

Identification of Cellular Factors Required for SARS-CoV-2 Replication.

Cells

Synowiec A, Jedrysik M, Branicki W, Klajmon A, Lei J, Owczarek K, Suo C, Szczepanski A, Wang J, Zhang P, Labaj PP, Pyrc K.
PMID: 34831382
Cells. 2021 Nov 13;10(11). doi: 10.3390/cells10113159.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the recently emerged virus responsible for the COVID-19 pandemic. Clinical presentation can range from asymptomatic disease and mild respiratory tract infection to severe disease with lung injury, multiorgan failure, and death....

N-Nitrosamines in Nitrite-Cured Chicken-Seal Salami.

Journal of food protection

Shahidi F, Synowiecki J, Sen NP.
PMID: 31137343
J Food Prot. 1995 Apr;58(4):446-447. doi: 10.4315/0362-028X-58.4.446.

The effect of inclusion of mechanically separated seal meat (MSSM) and seal protein hydrolyzate (SPH) on the formation of N-nitrosamines in chicken salami was investigated. Inclusion of MSSM (10 or 20%) or SPH (1 or 2%) in salami had...

Effect of Rehabilitation with Extremely Low Frequency Electromagnetic Field on Molecular Mechanism of Apoptosis in Post-Stroke Patients.

Brain sciences

Cichon N, Synowiec E, Miller E, Sliwinski T, Ceremuga M, Saluk-Bijak J, Bijak M.
PMID: 32366004
Brain Sci. 2020 Apr 30;10(5). doi: 10.3390/brainsci10050266.

Apoptosis in acute stroke is associated with a negative prognosis and is correlated with the severity of the neurological deficit. However, there is no evidence that indicates that, in the subacute phase of the stroke, the apoptosis process might...

Clinical importance of serum HE4 and MMP2 levels in endometrial cancer patients.

OncoTargets and therapy

Cymbaluk-Płoska A, Chudecka-Głaz A, Pius-Sadowska E, Sompolska-Rzechuła A, Machaliński B, Surowiec A, Menkiszak J.
PMID: 28721066
Onco Targets Ther. 2017 Jun 27;10:3169-3175. doi: 10.2147/OTT.S136750. eCollection 2017.

INTRODUCTION: Endometrial cancer is the one of the most common cancers of the genital organ. HE4 and MMP2 are both proteins whose serum levels increase in endometrial cancer.AIM: To explore the diagnostic potential of the serum levels of HE4...

Characteristics of chicken-seal salami.

Meat science

Shahidi F, Synowiecki J, Venugopal V, Pegg RB, Botta JR.
PMID: 22061677
Meat Sci. 1997 Apr;45(4):551-9. doi: 10.1016/s0309-1740(96)00038-1.

Mechanically separated seal meat (MSSM) at 10% (SM-10) and 20% (SM-20) or seal protein hydrolysate (SPH) at 1% (SPH-1) and 2% (SPH-2) prepared from MSSM were used to replace mechanically separated chicken meat (MSCM) in salami formulations. Cured products...

Adsorption of enzymes on krill chitin modified with carbon disulfide.

Biotechnology and bioengineering

Synowiecki J, Sikorska-Siondalska A, El-Bedawey Ael-F.
PMID: 18576424
Biotechnol Bioeng. 1987 Feb;29(3):352-4. doi: 10.1002/bit.260290309.

Krill chitin modified with carbon disulfide was used as a support of enzymes. The dithiocarbamino groups created after reaction of CS(2) with chitinous NH(2) can participate in binding the enzymes without denaturation and loss in activity. The stability of...

Immobilization of enzymes on krill chitin activated by formaldehyde.

Biotechnology and bioengineering

Synowiecki J, Sikorski ZE, Naczk M, Piotrzkowska H.
PMID: 18548442
Biotechnol Bioeng. 1982 Aug;24(8):1871-6. doi: 10.1002/bit.260240812.

No abstract available.

Clinical features and outcomes of germline mutation BRCA1-linked versus sporadic ovarian cancer patients.

Hereditary cancer in clinical practice

Synowiec A, Wcisło G, Bodnar L, Górski B, Szenajch J, Szarlej-Wcisło K, Szczylik C.
PMID: 26753012
Hered Cancer Clin Pract. 2016 Jan 08;14:1. doi: 10.1186/s13053-015-0044-z. eCollection 2016.

BACKGROUND: The role of germline mutations in BRCA1 and BRCA2 genes in the risk of the development of ovarian cancer is clinically well established. BRCA1/2 testing seems to have increasing role in clinical management in patients with advanced ovarian...

Lack of association between polymorphisms of the DNA base excision repair genes MUTYH and hOGG1 and keratoconus in a Polish subpopulation.

Archives of medical science : AMS

Synowiec E, Wójcik KA, Czubatka A, Polakowski P, Izdebska J, Szaflik J, Błasiak J, Szaflik JP.
PMID: 26528356
Arch Med Sci. 2015 Oct 12;11(5):1101-10. doi: 10.5114/aoms.2015.54867.

INTRODUCTION: Keratoconus (KC) is a non-inflammatory thinning of the cornea and a leading indication for corneal transplantation. Oxidative stress plays a role in the pathogenesis of this disease. The products of the hOGG1 and MUTYH genes play an important...

Responsive feedback: Towards a new paradigm to enhance intervention effectiveness.

Gates open research

Viswanath K, Synowiec C, Agha S.
PMID: 31131370
Gates Open Res. 2019 Mar 08;3:781. doi: 10.12688/gatesopenres.12937.1. eCollection 2019.

The current dominant models of intervention design in the development sector do not account for the complexity and unpredictability of implementation challenges. Decision makers and implementers need timely feedback during implementation to respond to field realities and to course-correct....

Showing 1 to 12 of 35 entries