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Showing 1 to 12 of 77 entries
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NTRK2 expression levels are reduced in laser captured pyramidal neurons from the anterior cingulate cortex in males with autism spectrum disorder.

Molecular autism

Chandley MJ, Crawford JD, Szebeni A, Szebeni K, Ordway GA.
PMID: 26000162
Mol Autism. 2015 May 16;6:28. doi: 10.1186/s13229-015-0023-2. eCollection 2015.

BACKGROUND: The anterior cingulate cortex (ACC) is a brain area involved in modulating behavior associated with social interaction, disruption of which is a core feature of autism spectrum disorder (ASD). Functional brain imaging studies demonstrate abnormalities of the ACC...

[The potential of three-dimensional tumor models and cell culturing in cancer research and diagnostics].

Magyar onkologia

Alföldi R, Szebeni JG, Puskás LG.
PMID: 26665190
Magy Onkol. 2015 Dec;59(4):303-9. Epub 2015 Jul 15.

In vitro testing of antitumor agents on human cancer cell lines has become essential in pharmaceutical research and in clinical practice. Although the most widely used technique is the two-dimensional cell growing protocol (in tissue culture plates), the new...

X-ray Laue Diffraction from Protein Crystals.

Science (New York, N.Y.)

Moffat K, Szebenyi D, Bilderback D.
PMID: 17746054
Science. 1984 Mar 30;223(4643):1423-5. doi: 10.1126/science.223.4643.1423.

In conventional x-ray diffraction experiments on single crystals, essentially monochromatic x-rays are used. If polychromatic x-rays derived from a synchrotron radiation spectrum are used, they generate a Laue diffraction pattern. Laue patterns from single crystals of macromolecules can be...

Practice effects with the NIMH AIDS abbreviated neuropsychological battery.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

McCaffrey RJ, Cousins JP, Westervelt HJ, Martynowicz M, Remick SC, Szebenyi S, Wagle WA, Bottomley PA, Hardy CJ, Haase RF.
PMID: 14588690
Arch Clin Neuropsychol. 1995 May;10(3):241-50.

The degree of practice effects with the Brief NIMH Neuropsychological Battery for HIV Infection and AIDS is reported using a 7-10 day test-retest interval. The patient groups were asymptomatic and symptomatic of HIV while the control group was made...

Room-temperature serial crystallography using a kinetically optimized microfluidic device for protein crystallization and on-chip X-ray diffraction.

IUCrJ

Heymann M, Opthalage A, Wierman JL, Akella S, Szebenyi DM, Gruner SM, Fraden S.
PMID: 25295176
IUCrJ. 2014 Aug 25;1:349-60. doi: 10.1107/S2052252514016960. eCollection 2014 Sep 01.

An emulsion-based serial crystallographic technology has been developed, in which nanolitre-sized droplets of protein solution are encapsulated in oil and stabilized by surfactant. Once the first crystal in a drop is nucleated, the small volume generates a negative feedback...

Crystal structure of diaphorin methanol monosolvate isolated from .

Acta crystallographica. Section E, Crystallographic communications

Szebenyi DM, Kriksunov I, Howe KJ, Ramsey JS, Hall DG, Heck ML, Krasnoff SB.
PMID: 29765742
Acta Crystallogr E Crystallogr Commun. 2018 Mar 02;74:445-449. doi: 10.1107/S2056989018002992. eCollection 2018 Apr 01.

The title compound C

Letter: Guidelines for the use of Electrophysiological Monitoring for Surgery of the Human Spinal Column and Spinal Cord.

Neurosurgery

Sala F, Skinner SA, Arle JE, Constantini S, Deletis V, Kothbauer KF, MacDonald DB, Shils J, Soto F, Szelenyi A.
PMID: 29893917
Neurosurgery. 2018 Aug 01;83(2):E82-E84. doi: 10.1093/neuros/nyy231.

No abstract available.

Immunoprofiling of Drosophila Hemocytes by Single-cell Mass Cytometry.

Genomics, proteomics & bioinformatics

Balog JÁ, Honti V, Kurucz É, Kari B, Puskás LG, Andó I, Szebeni GJ.
PMID: 33713850
Genomics Proteomics Bioinformatics. 2021 Apr;19(2):243-252. doi: 10.1016/j.gpb.2020.06.022. Epub 2021 Mar 10.

Single-cell mass cytometry (SCMC) combines features of traditional flow cytometry (i.e., fluorescence-activated cell sorting) with mass spectrometry, making it possible to measure several parameters at the single-cell level for a complex analysis of biological regulatory mechanisms. In this study,...

To PEGylate or not to PEGylate: immunological properties of nanomedicine's most popular component, poly(ethylene) glycol and its alternatives.

Advanced drug delivery reviews

Shi D, Beasock D, Fessler A, Szebeni J, Ljubimova JY, Afonin KA, Dobrovolskaia MA.
PMID: 34902516
Adv Drug Deliv Rev. 2021 Dec 10;114079. doi: 10.1016/j.addr.2021.114079. Epub 2021 Dec 10.

Poly(ethylene glycol) or PEG has a long history of use in medicine. Many conventional formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in biotechnology therapeutics as a tool to slow down drug...

Anti-PEG antibodies compromise the integrity of PEGylated lipid-based nanoparticles via complement.

Journal of controlled release : official journal of the Controlled Release Society

Estapé Senti M, de Jongh CA, Dijkxhoorn K, Verhoef JJF, Szebeni J, Storm G, Hack CE, Schiffelers RM, Fens MH, Boross P.
PMID: 34890719
J Control Release. 2021 Dec 07;341:475-486. doi: 10.1016/j.jconrel.2021.11.042. Epub 2021 Dec 07.

PEGylation of lipid-based nanoparticles and other nanocarriers is widely used to increase their stability and plasma half-life. However, either pre-existing or de novo formed anti-PEG antibodies can induce hypersensitivity reactions and accelerated blood clearance through binding to the nanoparticle...

Clinical validity of new ultrasound methods in the differential diagnosis of breast diseases.

Breast (Edinburgh, Scotland)

Szebeni A, Rahóty P, Besznyák I.
PMID: 14965715
Breast. 2002 Dec;11(6):489-95. doi: 10.1054/brst.2002.0468.

The clinical application of the extended-field-of-view (EFOV) technique, 3D ultrasonography (3D US) and a newly developed US method using a homogeneous tissue equivalent phantom, the so-called attenuation in phantom (AIPH) method, was evaluated in 200 patients with breast disease....

Thermal, Viscoelastic, Mechanical and Wear Behaviour of Nanoparticle Filled Polytetrafluoroethylene: A Comparison.

Polymers

Tóth LF, De Baets P, Szebényi G.
PMID: 32867317
Polymers (Basel). 2020 Aug 27;12(9). doi: 10.3390/polym12091940.

In this research work, unfilled and mono-filled polytetrafluoroethylene (PTFE) materials were developed and characterised by physical, thermal, viscoelastic, mechanical, and wear analysis. The applied fillers were graphene, alumina (Al

Showing 1 to 12 of 77 entries