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Reversal of intramyocellular lipid accumulation by lipophagy and a p62-mediated pathway.

Cell death discovery

Lam T, Harmancey R, Vasquez H, Gilbert B, Patel N, Hariharan V, Lee A, Covey M, Taegtmeyer H.
PMID: 27625792
Cell Death Discov. 2016 Aug 22;2:16061. doi: 10.1038/cddiscovery.2016.61. eCollection 2016.

We have previously observed the reversal of lipid droplet deposition in skeletal muscle of morbidly obese patients following bariatric surgery. We now investigated whether activation of autophagy is the mechanism underlying this observation. For this purpose, we incubated rat...

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Lam T, Harmancey R, Vasquez H, et al. Reversal of intramyocellular lipid accumulation by lipophagy and a p62-mediated pathway. Cell Death Discov. 2016;2:16061doi: 10.1038/cddiscovery.2016.61.
Lam, T., Harmancey, R., Vasquez, H., Gilbert, B., Patel, N., Hariharan, V., Lee, A., Covey, M., & Taegtmeyer, H. (2016). Reversal of intramyocellular lipid accumulation by lipophagy and a p62-mediated pathway. Cell death discovery, 216061. https://doi.org/10.1038/cddiscovery.2016.61
Lam, T, et al. "Reversal of intramyocellular lipid accumulation by lipophagy and a p62-mediated pathway." Cell death discovery vol. 2 (2016): 16061. doi: https://doi.org/10.1038/cddiscovery.2016.61
Lam T, Harmancey R, Vasquez H, Gilbert B, Patel N, Hariharan V, Lee A, Covey M, Taegtmeyer H. Reversal of intramyocellular lipid accumulation by lipophagy and a p62-mediated pathway. Cell Death Discov. 2016 Aug 22;2:16061. doi: 10.1038/cddiscovery.2016.61. eCollection 2016. PMID: 27625792; PMCID: PMC4993124.
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Decentralising and integrating HIV services in community-based health systems: a qualitative study of perceptions at macro, meso and micro levels of the health system.

BMJ global health

Otiso L, McCollum R, Mireku M, Karuga R, de Koning K, Taegtmeyer M.
PMID: 28588995
BMJ Glob Health. 2017 Jan 20;2(1):e000107. doi: 10.1136/bmjgh-2016-000107. eCollection 2017.

INTRODUCTION: HIV services at the community level in Kenya are currently delivered largely through vertical programmes. The funding for these programmes is declining at the same time as the tasks of delivering HIV services are being shifted to the...

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Otiso L, McCollum R, Mireku M, et al. Decentralising and integrating HIV services in community-based health systems: a qualitative study of perceptions at macro, meso and micro levels of the health system. BMJ Glob Health. 2017;2(1):e000107doi: 10.1136/bmjgh-2016-000107.
Otiso, L., McCollum, R., Mireku, M., Karuga, R., de Koning, K., & Taegtmeyer, M. (2017). Decentralising and integrating HIV services in community-based health systems: a qualitative study of perceptions at macro, meso and micro levels of the health system. BMJ global health, 2(1), e000107. https://doi.org/10.1136/bmjgh-2016-000107
Otiso, Lilian, et al. "Decentralising and integrating HIV services in community-based health systems: a qualitative study of perceptions at macro, meso and micro levels of the health system." BMJ global health vol. 2,1 (2017): e000107. doi: https://doi.org/10.1136/bmjgh-2016-000107
Otiso L, McCollum R, Mireku M, Karuga R, de Koning K, Taegtmeyer M. Decentralising and integrating HIV services in community-based health systems: a qualitative study of perceptions at macro, meso and micro levels of the health system. BMJ Glob Health. 2017 Jan 20;2(1):e000107. doi: 10.1136/bmjgh-2016-000107. eCollection 2017. PMID: 28588995; PMCID: PMC5321381.
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Computer-assisted learning in critical care: from ENIAC to HAL.

Critical care medicine

Tegtmeyer K, Ibsen L, Goldstein B.
PMID: 11496040
Crit Care Med. 2001 Aug;29(8):N177-82. doi: 10.1097/00003246-200108001-00006.

Computers are commonly used to serve many functions in today's modern intensive care unit. One of the most intriguing and perhaps most challenging applications of computers has been to attempt to improve medical education. With the introduction of the...

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Tegtmeyer K, Ibsen L, Goldstein B. Computer-assisted learning in critical care: from ENIAC to HAL. Crit Care Med. 2001;29(8):N177-82doi: 10.1097/00003246-200108001-00006.
Tegtmeyer, K., Ibsen, L., & Goldstein, B. (2001). Computer-assisted learning in critical care: from ENIAC to HAL. Critical care medicine, 29(8), N177-82. https://doi.org/10.1097/00003246-200108001-00006
Tegtmeyer, K, et al. "Computer-assisted learning in critical care: from ENIAC to HAL." Critical care medicine vol. 29,8 (2001): N177-82. doi: https://doi.org/10.1097/00003246-200108001-00006
Tegtmeyer K, Ibsen L, Goldstein B. Computer-assisted learning in critical care: from ENIAC to HAL. Crit Care Med. 2001 Aug;29(8):N177-82. doi: 10.1097/00003246-200108001-00006. PMID: 11496040.
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Rimonabant--a new weapon in the war on obesity.

Current hypertension reports

Taegtmeyer H, Lux TR.
PMID: 17087852
Curr Hypertens Rep. 2006 Dec;8(6):441-2. doi: 10.1007/s11906-006-0019-6.

No abstract available.

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Taegtmeyer H, Lux TR. Rimonabant--a new weapon in the war on obesity. Curr Hypertens Rep. 2006;8(6):441-2doi: 10.1007/s11906-006-0019-6.
Taegtmeyer, H., & Lux, T. R. (2006). Rimonabant--a new weapon in the war on obesity. Current hypertension reports, 8(6), 441-2. https://doi.org/10.1007/s11906-006-0019-6
Taegtmeyer, Heinrich, and Lux, Thomas R. "Rimonabant--a new weapon in the war on obesity." Current hypertension reports vol. 8,6 (2006): 441-2. doi: https://doi.org/10.1007/s11906-006-0019-6
Taegtmeyer H, Lux TR. Rimonabant--a new weapon in the war on obesity. Curr Hypertens Rep. 2006 Dec;8(6):441-2. doi: 10.1007/s11906-006-0019-6. PMID: 17087852.
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Myocardial energetics: still only the tip of an iceberg.

Heart, lung & circulation

Taegtmeyer H.
PMID: 16352098
Heart Lung Circ. 2003;12(1):3-6. doi: 10.1046/j.1444-2892.2003.00193.x.

No abstract available.

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Taegtmeyer H. Myocardial energetics: still only the tip of an iceberg. Heart Lung Circ. 2003;12(1):3-6doi: 10.1046/j.1444-2892.2003.00193.x.
Taegtmeyer, H. (2003). Myocardial energetics: still only the tip of an iceberg. Heart, lung & circulation, 12(1), 3-6. https://doi.org/10.1046/j.1444-2892.2003.00193.x
Taegtmeyer, Heinrich. "Myocardial energetics: still only the tip of an iceberg." Heart, lung & circulation vol. 12,1 (2003): 3-6. doi: https://doi.org/10.1046/j.1444-2892.2003.00193.x
Taegtmeyer H. Myocardial energetics: still only the tip of an iceberg. Heart Lung Circ. 2003;12(1):3-6. doi: 10.1046/j.1444-2892.2003.00193.x. PMID: 16352098.
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The politics of TB: TB control services need tailoring for new arrivals, not vice versa.

Chronic respiratory disease

Wang Y, Taegtmeyer M, Squire SB, Theobald SJ.
PMID: 18303102
Chron Respir Dis. 2008;5(1):49-51. doi: 10.1177/1479972307086173.

High rates of TB amongst new arrivals to the UK require flexible, innovative responses that go beyond traditional biomedical models and take into account the needs of these heterogeneous groups. This article explores the merging of public health and...

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Wang Y, Taegtmeyer M, Squire SB, et al. The politics of TB: TB control services need tailoring for new arrivals, not vice versa. Chron Respir Dis. 2008;5(1):49-51doi: 10.1177/1479972307086173.
Wang, Y., Taegtmeyer, M., Squire, S. B., & Theobald, S. J. (2008). The politics of TB: TB control services need tailoring for new arrivals, not vice versa. Chronic respiratory disease, 5(1), 49-51. https://doi.org/10.1177/1479972307086173
Wang, Y, et al. "The politics of TB: TB control services need tailoring for new arrivals, not vice versa." Chronic respiratory disease vol. 5,1 (2008): 49-51. doi: https://doi.org/10.1177/1479972307086173
Wang Y, Taegtmeyer M, Squire SB, Theobald SJ. The politics of TB: TB control services need tailoring for new arrivals, not vice versa. Chron Respir Dis. 2008;5(1):49-51. doi: 10.1177/1479972307086173. PMID: 18303102.
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PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463: A novel pathway in regulating Rac1 GTPase function.

Gut microbes

Backert S, Kenny B, Gerhard R, Tegtmeyer N, Brandt S.
PMID: 21326916
Gut Microbes. 2010 Mar;1(2):94-99. doi: 10.4161/gmic.1.2.11437. Epub 2010 Feb 08.

Type-III or type-IV secretion systems of many Gram-negative bacterial pathogens inject effector proteins into host cells that modulate cellular functions in their favour. A preferred target of these effectors is the actin-cytoskeleton as shown by studies using the gastric...

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Backert S, Kenny B, Gerhard R, et al. PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463: A novel pathway in regulating Rac1 GTPase function. Gut Microbes. 2010;1(2):94-99doi: 10.4161/gmic.1.2.11437.
Backert, S., Kenny, B., Gerhard, R., Tegtmeyer, N., & Brandt, S. (2010). PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463: A novel pathway in regulating Rac1 GTPase function. Gut microbes, 1(2), 94-99. https://doi.org/10.4161/gmic.1.2.11437
Backert, Steffen, et al. "PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463: A novel pathway in regulating Rac1 GTPase function." Gut microbes vol. 1,2 (2010): 94-99. doi: https://doi.org/10.4161/gmic.1.2.11437
Backert S, Kenny B, Gerhard R, Tegtmeyer N, Brandt S. PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463: A novel pathway in regulating Rac1 GTPase function. Gut Microbes. 2010 Mar;1(2):94-99. doi: 10.4161/gmic.1.2.11437. Epub 2010 Feb 08. PMID: 21326916; PMCID: PMC3023586.
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Is quality affordable for community health systems? Costs of integrating quality improvement into close-to-community health programmes in five low-income and middle-income countries.

BMJ global health

Kumar MB, Madan JJ, Achieng MM, Limato R, Ndima S, Kea AZ, Chikaphupha KR, Barasa E, Taegtmeyer M.
PMID: 31354971
BMJ Glob Health. 2019 Jul 08;4(4):e001390. doi: 10.1136/bmjgh-2019-001390. eCollection 2019.

INTRODUCTION: Countries aspiring to universal health coverage view close-to-community (CTC) providers as a low-cost means of increasing coverage. However, due to lack of coordination and unreliable funding, the quality of large-scale CTC healthcare provision is highly variable and routine...

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Kumar MB, Madan JJ, Achieng MM, et al. Is quality affordable for community health systems? Costs of integrating quality improvement into close-to-community health programmes in five low-income and middle-income countries. BMJ Glob Health. 2019;4(4):e001390doi: 10.1136/bmjgh-2019-001390.
Kumar, M. B., Madan, J. J., Achieng, M. M., Limato, R., Ndima, S., Kea, A. Z., Chikaphupha, K. R., Barasa, E., & Taegtmeyer, M. (2019). Is quality affordable for community health systems? Costs of integrating quality improvement into close-to-community health programmes in five low-income and middle-income countries. BMJ global health, 4(4), e001390. https://doi.org/10.1136/bmjgh-2019-001390
Kumar, Meghan Bruce, et al. "Is quality affordable for community health systems? Costs of integrating quality improvement into close-to-community health programmes in five low-income and middle-income countries." BMJ global health vol. 4,4 (2019): e001390. doi: https://doi.org/10.1136/bmjgh-2019-001390
Kumar MB, Madan JJ, Achieng MM, Limato R, Ndima S, Kea AZ, Chikaphupha KR, Barasa E, Taegtmeyer M. Is quality affordable for community health systems? Costs of integrating quality improvement into close-to-community health programmes in five low-income and middle-income countries. BMJ Glob Health. 2019 Jul 08;4(4):e001390. doi: 10.1136/bmjgh-2019-001390. eCollection 2019. PMID: 31354971; PMCID: PMC6626522.
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Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths.

Virus evolution

Moreira-Soto A, Arroyo-Murillo F, Sander AL, Rasche A, Corman V, Tegtmeyer B, Steinmann E, Corrales-Aguilar E, Wieseke N, Avey-Arroyo J, Drexler JF.
PMID: 32704383
Virus Evol. 2020 Apr 25;6(2):veaa033. doi: 10.1093/ve/veaa033. eCollection 2020 Jul.

The genealogy of the hepatitis C virus (HCV) and the genus

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Moreira-Soto A, Arroyo-Murillo F, Sander AL, et al. Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths. Virus Evol. 2020;6(2):veaa033doi: 10.1093/ve/veaa033.
Moreira-Soto, A., Arroyo-Murillo, F., Sander, A. L., Rasche, A., Corman, V., Tegtmeyer, B., Steinmann, E., Corrales-Aguilar, E., Wieseke, N., Avey-Arroyo, J., & Drexler, J. F. (2020). Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths. Virus evolution, 6(2), veaa033. https://doi.org/10.1093/ve/veaa033
Moreira-Soto, Andres, et al. "Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths." Virus evolution vol. 6,2 (2020): veaa033. doi: https://doi.org/10.1093/ve/veaa033
Moreira-Soto A, Arroyo-Murillo F, Sander AL, Rasche A, Corman V, Tegtmeyer B, Steinmann E, Corrales-Aguilar E, Wieseke N, Avey-Arroyo J, Drexler JF. Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths. Virus Evol. 2020 Apr 25;6(2):veaa033. doi: 10.1093/ve/veaa033. eCollection 2020 Jul. PMID: 32704383; PMCID: PMC7368370.
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Actionable Metabolic Pathways in Heart Failure and Cancer-Lessons From Cancer Cell Metabolism.

Frontiers in cardiovascular medicine

Karlstaedt A, Schiffer W, Taegtmeyer H.
PMID: 29971237
Front Cardiovasc Med. 2018 Jun 19;5:71. doi: 10.3389/fcvm.2018.00071. eCollection 2018.

Recent advances in cancer cell metabolism provide unprecedented opportunities for a new understanding of heart metabolism and may offer new approaches for the treatment of heart failure. Key questions driving the cancer field to understand how tumor cells reprogram...

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Karlstaedt A, Schiffer W, Taegtmeyer H. Actionable Metabolic Pathways in Heart Failure and Cancer-Lessons From Cancer Cell Metabolism. Front Cardiovasc Med. 2018;5:71doi: 10.3389/fcvm.2018.00071.
Karlstaedt, A., Schiffer, W., & Taegtmeyer, H. (2018). Actionable Metabolic Pathways in Heart Failure and Cancer-Lessons From Cancer Cell Metabolism. Frontiers in cardiovascular medicine, 571. https://doi.org/10.3389/fcvm.2018.00071
Karlstaedt, Anja, et al. "Actionable Metabolic Pathways in Heart Failure and Cancer-Lessons From Cancer Cell Metabolism." Frontiers in cardiovascular medicine vol. 5 (2018): 71. doi: https://doi.org/10.3389/fcvm.2018.00071
Karlstaedt A, Schiffer W, Taegtmeyer H. Actionable Metabolic Pathways in Heart Failure and Cancer-Lessons From Cancer Cell Metabolism. Front Cardiovasc Med. 2018 Jun 19;5:71. doi: 10.3389/fcvm.2018.00071. eCollection 2018. PMID: 29971237; PMCID: PMC6018530.
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Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy.

Journal of molecular and cellular cardiology

Davogustto GE, Salazar RL, Vasquez HG, Karlstaedt A, Dillon WP, Guthrie PH, Martin JR, Vitrac H, De La Guardia G, Vela D, Ribas-Latre A, Baumgartner C, Eckel-Mahan K, Taegtmeyer H.
PMID: 34081952
J Mol Cell Cardiol. 2021 Sep;158:115-127. doi: 10.1016/j.yjmcc.2021.05.016. Epub 2021 Jun 01.

RATIONALE: The nutrient sensing mechanistic target of rapamycin complex 1 (mTORC1) and its primary inhibitor, tuberin (TSC2), are cues for the development of cardiac hypertrophy. The phenotype of mTORC1 induced hypertrophy is unknown.OBJECTIVE: To examine the impact of sustained...

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Davogustto GE, Salazar RL, Vasquez HG, et al. Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy. J Mol Cell Cardiol. 2021;158:115-127doi: 10.1016/j.yjmcc.2021.05.016.
Davogustto, G. E., Salazar, R. L., Vasquez, H. G., Karlstaedt, A., Dillon, W. P., Guthrie, P. H., Martin, J. R., Vitrac, H., De La Guardia, G., Vela, D., Ribas-Latre, A., Baumgartner, C., Eckel-Mahan, K., & Taegtmeyer, H. (2021). Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy. Journal of molecular and cellular cardiology, 158115-127. https://doi.org/10.1016/j.yjmcc.2021.05.016
Davogustto, Giovanni E, et al. "Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy." Journal of molecular and cellular cardiology vol. 158 (2021): 115-127. doi: https://doi.org/10.1016/j.yjmcc.2021.05.016
Davogustto GE, Salazar RL, Vasquez HG, Karlstaedt A, Dillon WP, Guthrie PH, Martin JR, Vitrac H, De La Guardia G, Vela D, Ribas-Latre A, Baumgartner C, Eckel-Mahan K, Taegtmeyer H. Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy. J Mol Cell Cardiol. 2021 Sep;158:115-127. doi: 10.1016/j.yjmcc.2021.05.016. Epub 2021 Jun 01. PMID: 34081952; PMCID: PMC8630806.
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Code Team Training: Demonstrating Adherence to AHA Guidelines During Pediatric Code Blue Activations.

Pediatric emergency care

Stewart C, Shoemaker J, Keller-Smith R, Edmunds K, Davis A, Tegtmeyer K.
PMID: 29040245
Pediatr Emerg Care. 2021 Dec 01;37(12):e1658-e1662. doi: 10.1097/PEC.0000000000001307.

OBJECTIVE: Pediatric code blue activations are infrequent events with a high mortality rate despite the best effort of code teams. The best method for training these code teams is debatable; however, it is clear that training is needed to...

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Stewart C, Shoemaker J, Keller-Smith R, et al. Code Team Training: Demonstrating Adherence to AHA Guidelines During Pediatric Code Blue Activations. Pediatr Emerg Care. 2021;37(12):e1658-e1662doi: 10.1097/PEC.0000000000001307.
Stewart, C., Shoemaker, J., Keller-Smith, R., Edmunds, K., Davis, A., & Tegtmeyer, K. (2021). Code Team Training: Demonstrating Adherence to AHA Guidelines During Pediatric Code Blue Activations. Pediatric emergency care, 37(12), e1658-e1662. https://doi.org/10.1097/PEC.0000000000001307
Stewart, Claire, et al. "Code Team Training: Demonstrating Adherence to AHA Guidelines During Pediatric Code Blue Activations." Pediatric emergency care vol. 37,12 (2021): e1658-e1662. doi: https://doi.org/10.1097/PEC.0000000000001307
Stewart C, Shoemaker J, Keller-Smith R, Edmunds K, Davis A, Tegtmeyer K. Code Team Training: Demonstrating Adherence to AHA Guidelines During Pediatric Code Blue Activations. Pediatr Emerg Care. 2021 Dec 01;37(12):e1658-e1662. doi: 10.1097/PEC.0000000000001307. PMID: 29040245.
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Showing 1 to 12 of 101 entries