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Apical localization of sodium-dependent glucose transporter SGLT1 is maintained by cholesterol and microtubules.

Acta histochemica et cytochemica

Suzuki T, Matsuzaki T, Hagiwara H, Aoki T, Tajika-Takahashi Y, Takata K.
PMID: 17327902
Acta Histochem Cytochem. 2006 Dec 28;39(6):155-61. doi: 10.1267/ahc.06024. Epub 2006 Dec 06.

A GFP-labeled sodium-dependent glucose transporter SGLT1 (SGLT-GFP) was transfected into MDCK cells. SGLT-GFP was localized at the apical membrane in confluent cells. When cellular cholesterol was depleted by methyl-beta-cyclodextrin (MbetaCD) treatment, the localization of SGLT-GFP gradually switched from apical...

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