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Showing 1 to 7 of 7 entries
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Atovaquone/proguanil-induced autoimmune-like hepatitis.

Hepatology communications

Terziroli Beretta-Piccoli B, Mieli-Vergani G, Bertoli R, Mazzucchelli L, Nofziger C, Paulmichl M, Vergani D.
PMID: 29404460
Hepatol Commun. 2017 May 08;1(4):293-298. doi: 10.1002/hep4.1039. eCollection 2017 Jun.

We report a novel association between the commonly used antimalarial medication atovaquone/proguanil and drug-induced autoimmune-like hepatitis. The patient developed severe liver disease fulfilling biochemical, immunologic, and histologic criteria for the diagnosis of autoimmune hepatitis after the inadvertent rechallenge with...

A reasoned approach to the treatment of autoimmune hepatitis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Vergani D, Terziroli Beretta-Piccoli B, Mieli-Vergani G.
PMID: 34162505
Dig Liver Dis. 2021 Nov;53(11):1381-1393. doi: 10.1016/j.dld.2021.05.033. Epub 2021 Jun 23.

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease affecting all ages, characterised by elevated transaminase and immunoglobulin G levels, positive autoantibodies, interface hepatitis on histology and good response to immunosuppressive treatment. If untreated, it has a poor prognosis....

A patient with primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis variant syndrome.

Journal of translational autoimmunity

Terziroli Beretta-Piccoli B, Mazzucchelli L, Taiana C, Mossi G, Usai C, Vergani D, Mieli-Vergani G.
PMID: 32743518
J Transl Autoimmun. 2019 Dec 17;3:100033. doi: 10.1016/j.jtauto.2019.100033. eCollection 2020.

Overlap between autoimmune hepatitis (AIH) and either primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC) is not rare and has extensively been reported. We herein report the first well documented case of triple overlap. A 68-year-old male patient...

Autoimmune Hepatitis: Serum Autoantibodies in Clinical Practice.

Clinical reviews in allergy & immunology

Terziroli Beretta-Piccoli B, Mieli-Vergani G, Vergani D.
PMID: 34491531
Clin Rev Allergy Immunol. 2021 Sep 07; doi: 10.1007/s12016-021-08888-9. Epub 2021 Sep 07.

Circulating autoantibodies are a key diagnostic tool in autoimmune hepatitis (AIH), being positive in 95% of the cases if tested according to dedicated guidelines issued by the International Autoimmune Hepatitis Group. They also allow the distinction between type 1...

Autoimmmune hepatitis.

Cellular & molecular immunology

Terziroli Beretta-Piccoli B, Mieli-Vergani G, Vergani D.
PMID: 34580437
Cell Mol Immunol. 2021 Sep 27; doi: 10.1038/s41423-021-00768-8. Epub 2021 Sep 27.

Autoimmune hepatitis (AIH) is a T-cell mediated, inflammatory liver disease affecting all ages and characterized by female preponderance, elevated serum transaminase and immunoglobulin G levels, positive circulating autoantibodies, and presence of interface hepatitis at liver histology. AIH type 1,...

ABCB4 variants in adult patients with cholestatic disease are frequent and underdiagnosed.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Avena A, Puggelli S, Morris M, Cerny A, Andrade AR, Pareti E, Bihl F, Cassatella D, Moix I, Merlo E, Rougemont AL, Majno-Hurst P, Vergani D, Mieli-Vergani G, Terziroli Beretta-Piccoli B.
PMID: 33390354
Dig Liver Dis. 2021 Mar;53(3):329-344. doi: 10.1016/j.dld.2020.12.003. Epub 2020 Dec 31.

BACKGROUND: Heterozygous ABCB4 variants are not routinely tested in adults with cholestasis because of their supposed rarity and high costs.METHODS: Nineteen adult patients presenting with unexplained cholestasis, and/or recurrent gallstones were included; genotyping was not done in five due...

A reasoned approach to the treatment of autoimmune hepatitis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Vergani D, Terziroli Beretta-Piccoli B, Mieli-Vergani G.
PMID: 34162505
Dig Liver Dis. 2021 Nov;53(11):1381-1393. doi: 10.1016/j.dld.2021.05.033. Epub 2021 Jun 23.

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease affecting all ages, characterised by elevated transaminase and immunoglobulin G levels, positive autoantibodies, interface hepatitis on histology and good response to immunosuppressive treatment. If untreated, it has a poor prognosis....

Showing 1 to 7 of 7 entries