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Showing 1 to 12 of 114 entries
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Study of Selected Outcomes of Medical Students Who Fail USMLE Step 1.

Medical education online

Biskobing DM, Lawson SR, Messmer JM, Hoban JD.
PMID: 28253772
Med Educ Online. 2006 Dec;11(1):4589. doi: 10.3402/meo.v11i.4589.

PURPOSE: Passage of the United States Medical Licensing Exam (USMLE) is required to obtain a medical license in the United States. Currently the majority of US medical schools require passage of USMLE Step 1 for either promotion to the...

Biosimilars and the extrapolation of indications for inflammatory conditions.

Biologics : targets & therapy

Tesser JR, Furst DE, Jacobs I.
PMID: 28255229
Biologics. 2017 Feb 17;11:5-11. doi: 10.2147/BTT.S124476. eCollection 2017.

Extrapolation is the approval of a biosimilar for use in an indication held by the originator biologic not directly studied in a comparative clinical trial with the biosimilar. Extrapolation is a scientific rationale that bridges all the data collected...

Introducing a New Series: Immunotherapy Facts and Hopes.

Clinical cancer research : an official journal of the American Association for Cancer Research

Melero I, Sznol M, Tessmer MS, Whiteside TL, Wolchok JD.
PMID: 29476022
Clin Cancer Res. 2018 Apr 15;24(8):1773-1774. doi: 10.1158/1078-0432.CCR-18-0408. Epub 2018 Feb 23.

No abstract available.

RBM10 Modulates Apoptosis and Influences TNF-α Gene Expression.

Journal of cell death

Wang K, Bacon ML, Tessier JJ, Rintala-Maki ND, Tang V, Sutherland LC.
PMID: 26446321
J Cell Death. 2012 Jan 27;5:1-19. doi: 10.4137/JCD.S9073. eCollection 2012.

Recent evidence suggests that protein encoded by the RNA Binding Motif 10 (RBM10) gene has the ability to modulate apoptosis. The objective of this study was to test this hypothesis by manipulating RBM10 expression levels and examining the downstream...

Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [(18)F] FDG-PET imaging combined with proteomic approaches.

EJNMMI research

Tegnebratt T, Ruge E, Bader S, Ishii N, Aida S, Yoshimura Y, Ooi CH, Lu L, Mitsios N, Meresse V, Mulder J, Pawlak M, Venturi M, Tessier J, Stone-Elander S.
PMID: 26116108
EJNMMI Res. 2014 Dec;4(1):34. doi: 10.1186/s13550-014-0034-6. Epub 2014 Sep 09.

BACKGROUND: Inhibition of mitogen-activated protein kinase (MEK, also known as MAPK2, MAPKK), a key molecule of the Ras/MAPK (mitogen-activated protein kinase) pathway, has shown promising effects on B-raf-mutated and some RAS (rat sarcoma)-activated tumors in clinical trials. The objective...

Old fronds serve as a vernal carbon source in the wintergreen fern Dryopteris intermedia (Aspleniaceae).

American journal of botany

Tessier JT, Bornn MP.
PMID: 21642204
Am J Bot. 2007 Jan;94(1):25-8. doi: 10.3732/ajb.94.1.25.

Maintaining green leaves beyond the growing season has been hypothesized to benefit plants by supplying either a nutrient or a carbon source. Understanding such ecophysiological aspects of plants will help us to appreciate how a species functions in its...

Efficient monochromator to isolate VUV light generated by four-wave mixing techniques.

Applied optics

Vondrasek WA, Okajima S, Hessler JP.
PMID: 20539514
Appl Opt. 1988 Oct 01;27(19):4057-61. doi: 10.1364/AO.27.004057.

The lateral chromatic aberration from a LiF lens, which is positioned off-axis with respect to the incident light beams, is used to isolate the VUV light generated by the four-wave mixing technique from the intense pump light. The transmittance...

[Not Available].

Canadian family physician Medecin de famille canadien

Schick E, Tessier J.
PMID: 21229029
Can Fam Physician. 1991 May;37:1220-9.

Urodynamics has profoundly changed our understanding of the physiopathology of urinary incontinence which is, first and foremost, a functional problem. The urodynamic study is the only diagnostic tool which makes it possible to explore the functioning of the urethra...

Phonon-induced relaxation in excited optical states of trivalent neptunium in LaCl3.

Optics letters

Hessler JP, Brundage RT, Hegarty J, Yen WM.
PMID: 19693224
Opt Lett. 1980 Aug 01;5(8):348. doi: 10.1364/ol.5.000348.

No abstract available.

[18 F]FDG-PET imaging is an early non-invasive pharmacodynamic biomarker for a first-in-class dual MEK/Raf inhibitor, RO5126766 (CH5126766), in preclinical xenograft models.

EJNMMI research

Tegnebratt T, Lu L, Lee L, Meresse V, Tessier J, Ishii N, Harada N, Pisa P, Stone-Elander S.
PMID: 24041012
EJNMMI Res. 2013 Sep 16;3(1):67. doi: 10.1186/2191-219X-3-67.

BACKGROUND: Positron emission tomography (PET) with [2-18 F]-2-fluoro-2-deoxy-D-glucose ([18 F]FDG-PET) was acquired at multiple time-points a) to monitor the early response to RO5126766 (CH5126766) in xenograft models b) to evaluate non-invasive small animal [18 F]FDG-PET imaging as a biomarker...

Dissociation of high np singlet Rydberg levels of H2 by a pulsed electric field.

Physical review letters

Glab WL, Hessler JP.
PMID: 10039683
Phys Rev Lett. 1989 Mar 27;62(13):1472-1475. doi: 10.1103/PhysRevLett.62.1472.

No abstract available.

Yoga-Based Classes for Veterans With Severe Mental Illness: Development, Dissemination, and Assessment.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS

Baker MR, Tessier JM, Meyer HB, Sones AC, Sachinvala N, Ames D.
PMID: 30766024
Fed Pract. 2015 Oct;32(10):19-25.

Throughout 8 weeks of yoga-based wellness classes, veterans were assessed for perceived benefits, pain, stress, and biological, psychological, social, and spiritual wellness.

Showing 1 to 12 of 114 entries