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Showing 1 to 12 of 32 entries
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Determining the transmembrane topology of the presenilins.

Methods in molecular medicine

Thinakaran G, Doan A.
PMID: 21318526
Methods Mol Med. 2000;32:283-96. doi: 10.1385/1-59259-195-7:283.

Mutations in two related genes, PS1 (1) and PS2 (2,3) located on chromosomes 14 and 1, respectively, account for the majority of early onset cases of familial Alzheimer's disease (FAD). PS1 and PS2 are predominantly localized in the endoplasmic...

Laparoscopic management of appendicular mass.

Journal of minimal access surgery

Shindholimath VV, Thinakaran K, Rao TN, Veerappa YV.
PMID: 21523236
J Minim Access Surg. 2011 Apr;7(2):136-40. doi: 10.4103/0972-9941.78345.

BACKGROUND: Laparoscopic appendectomy is becoming the preferred technique for treating acute appendicitis. However, its role in the treatment of complicated appendicitis is controversial. This study was undertaken to assess the feasibility of laparoscopic appendectomy for appendicular mass.MATERIALS AND METHODS:...

Self-assembly of a Si-based cage by the formation of 24 equivalent covalent bonds.

Chemical communications (Cambridge, England)

Holmes JL, Abrahams BF, Ahveninen A, Boughton BA, Hudson TA, Robson R, Thinagaran D.
PMID: 30283934
Chem Commun (Camb). 2018 Oct 28;54(84):11877-11880. doi: 10.1039/c8cc06405a. Epub 2018 Oct 04.

A robust, nano-sized covalent cage, of composition, [(PhSi)

Silverleaf Nightshade (Solanum elaeagnifolium), a Reservoir Host for 'Candidatus Liberibacter solanacearum', the Putative Causal Agent of Zebra Chip Disease of Potato.

Plant disease

Thinakaran J, Pierson E, Kunta M, Munyaneza JE, Rush CM, Henne DC.
PMID: 30690968
Plant Dis. 2015 Jul;99(7):910-915. doi: 10.1094/PDIS-12-14-1254-RE. Epub 2015 May 15.

Zebra chip disease of potato is caused by the bacterial pathogen 'Candidatus Liberibacter solanacearum' and is a growing concern for commercial potato production in several countries in North and Central America and New Zealand. 'Ca. L. solanacearum' is vectored...

Mass Spectrometry Based Imaging of Labile Glucosides in Plants.

Frontiers in plant science

Bøgeskov Schmidt F, Heskes AM, Thinagaran D, Lindberg Møller B, Jørgensen K, Boughton BA.
PMID: 30002667
Front Plant Sci. 2018 Jun 28;9:892. doi: 10.3389/fpls.2018.00892. eCollection 2018.

Mass spectrometry based imaging is a powerful tool to investigate the spatial distribution of a broad range of metabolites across a variety of sample types. The recent developments in instrumentation and computing capabilities have increased the mass range, sensitivity...

Ultra sensitive detection of Cd (II) using reduced graphene oxide/carboxymethyl cellulose/glutathione modified electrode.

Carbohydrate polymers

Priya T, Dhanalakshmi N, Thennarasu S, Thinakaran N.
PMID: 30007624
Carbohydr Polym. 2018 Oct 01;197:366-374. doi: 10.1016/j.carbpol.2018.06.024. Epub 2018 Jun 06.

The present work describes the electrochemical detection of Cd

Spontaneous Formation of Cationic Vesicles in Aqueous DDAB-Lecithin Mixtures for Efficient Plasmid DNA Complexation and Gene Transfection.

ACS applied bio materials

Shelar SB, Dey A, Gawali SL, Dhinakaran S, Barick KC, Basu M, Uppal S, Hassan PA.
PMID: 35006928
ACS Appl Bio Mater. 2021 Aug 16;4(8):6005-6015. doi: 10.1021/acsabm.1c00165. Epub 2021 Jun 09.

Cationic liposomes have become an attractive tool to deliver genes and interfering RNA into cells. Herein, we report the application of spontaneously formed cationic vesicles in mixtures of lecithin and cationic amphiphiles for efficient transfection of plasmid DNA and...

All arthroscopic medial meniscus inside out repair- Technical note.

Journal of clinical orthopaedics and trauma

Coimbatore Balasubramaniam VS, Dhinakaran GK, Sahanand S, Rajan DV.
PMID: 32523303
J Clin Orthop Trauma. 2020 May;11:S414-S417. doi: 10.1016/j.jcot.2020.03.027. Epub 2020 Apr 09.

Concomitant meniscal injuries are common in patients with anterior cruciate ligament (ACL) insufficiency. Along with ACL reconstruction, meniscal repair offers better outcomes. This requires multiple incisions for both procedures. We present a novel technique of medial meniscus inside out...

Treatment-related fluctuation in Guillain-Barre syndrome.

Journal of neurosciences in rural practice

Thivakaran T, Gamage R, Gooneratne IK.
PMID: 21897682
J Neurosci Rural Pract. 2011 Jul;2(2):168-70. doi: 10.4103/0976-3147.83585.

Guillain-Barre syndrome (GBS) is usually a monophasic illness but relapses occur. A 55-year-old female with hypertension and vitiligo presented with acute inflammatory demyelinating polyradiculoneuropathy. She improved with immunoglobulin treatment started on day 6 of illness, but relapsed on day...

Synthesis and electrochemical properties of environmental free l-glutathione grafted graphene oxide/ZnO nanocomposite for highly selective piroxicam sensing.

Journal of pharmaceutical analysis

Dhanalakshmi N, Priya T, Thennarasu S, Sivanesan S, Thinakaran N.
PMID: 33717611
J Pharm Anal. 2021 Feb;11(1):48-56. doi: 10.1016/j.jpha.2020.02.001. Epub 2020 Feb 06.

A simple and reliable strategy was proposed to engineer the glutathione grafted graphene oxide/ZnO nanocomposite (glutathione-GO/ZnO) as electrode material for the high-performance piroxicam sensor. The prepared glutathione-GO/ZnO nanocomposite was well characterized by X-ray diffraction (XRD), Fourier transform infrared spectrum...

Pathological and physiological functions of presenilins.

Molecular neurodegeneration

Vetrivel KS, Zhang YW, Xu H, Thinakaran G.
PMID: 16930451
Mol Neurodegener. 2006 Jun 12;1:4. doi: 10.1186/1750-1326-1-4.

Mutations in PSEN1 and PSEN2 genes account for the majority of cases of early-onset familial Alzheimer disease. Since the first prediction of a genetic link between PSEN1 and PSEN2 with Alzheimer's disease, many research groups from both academia and...

Oral myiasis.

Indian journal of palliative care

Saravanan T, Mohan MA, Thinakaran M, Ahammed S.
PMID: 25709196
Indian J Palliat Care. 2015 Jan-Apr;21(1):92-4. doi: 10.4103/0973-1075.150200.

Myiasis is a pathologic condition in humans occurring because of parasitic infestation. Parasites causing myiasis belong to the order Diptera. Oral myiasis is seen secondary to oral wounds, suppurative lesions, and extraction wounds, especially in individuals with neurological deficit....

Showing 1 to 12 of 32 entries