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Showing 1 to 12 of 276 entries
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Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.

World journal of hepatology

Reiter FP, Wimmer R, Wottke L, Artmann R, Nagel JM, Carranza MO, Mayr D, Rust C, Fickert P, Trauner M, Gerbes AL, Hohenester S, Denk GU.
PMID: 27004088
World J Hepatol. 2016 Mar 18;8(8):401-10. doi: 10.4254/wjh.v8.i8.401.

AIM: To study the interleukin-1 (IL-1) pathway as a therapeutic target for liver fibrosis in vitro and in vivo using the ATP-binding cassette transporter b4(-/-) (Abcb4(-/-)) mouse model.METHODS: Female and male Abcb4(-/-) mice from 6 to 13 mo of...

Recent advances in understanding and managing cholestasis.

F1000Research

Wagner M, Trauner M.
PMID: 27134744
F1000Res. 2016 Apr 19;5. doi: 10.12688/f1000research.8012.1. eCollection 2016.

Cholestatic liver diseases are hereditary or acquired disorders with impaired hepatic excretion and enterohepatic circulation of bile acids and other cholephiles. The distinct pathological mechanisms, particularly for the acquired forms of cholestasis, are not fully revealed, but advances in...

High-resolution forest mapping for behavioural studies in the Nature Reserve 'Les Nouragues', French Guiana.

Journal of maps

Ringler M, Mangione R, Pašukonis A, Rainer G, Gyimesi K, Felling J, Kronaus H, Réjou-Méchain M, Chave J, Reiter K, Ringler E.
PMID: 27053943
J Maps. 2014 Oct 28;12(1):26-32. doi: 10.1080/17445647.2014.972995.

For animals with spatially complex behaviours at relatively small scales, the resolution of a global positioning system (GPS) receiver location is often below the resolution needed to correctly map animals' spatial behaviour. Natural conditions such as canopy cover, canyons...

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Nature

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie Helmut Fuchs SM, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Nutter SNLMJ, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, Wurst W, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SDM, Adams DJ, Lloyd KCK, McKerlie C, Beaudet AL, Murray MBSA.
PMID: 29144450
Nature. 2017 Nov 16;551(7680):398. doi: 10.1038/nature24643. Epub 2017 Nov 08.

This corrects the article DOI: 10.1038/nature19356.

Growth Hormone Research Society perspective on biomarkers of GH action in children and adults.

Endocrine connections

Johannsson G, Bidlingmaier M, Biller BMK, Boguszewski M, Casanueva FF, Chanson P, Clayton PE, Choong CS, Clemmons D, Dattani M, Frystyk J, Ho K, Hoffman AR, Horikawa R, Juul A, Kopchick JJ, Luo X, Neggers S, Netchine I, Olsson DS, Radovick S, Rosenfeld R, Ross RJ, Schilbach K, Solberg P, Strasburger C, Trainer P, Yuen KCJ, Wickstrom K, Jorgensen JOL.
PMID: 29483159
Endocr Connect. 2018 Mar;7(3):R126-R134. doi: 10.1530/EC-18-0047. Epub 2018 Feb 26.

OBJECTIVE: The Growth Hormone Research Society (GRS) convened a Workshop in 2017 to evaluate clinical endpoints, surrogate endpoints and biomarkers during GH treatment of children and adults and in patients with acromegaly.PARTICIPANTS: GRS invited 34 international experts including clinicians,...

Isotopes of nitrogen on Mars: Atmospheric measurements by Curiosity's mass spectrometer.

Geophysical research letters

Wong MH, Atreya SK, Mahaffy PN, Franz HB, Malespin C, Trainer MG, Stern JC, Conrad PG, Manning HL, Pepin RO, Becker RH, McKay CP, Owen TC, Navarro-González R, Jones JH, Jakosky BM, Steele A.
PMID: 26074632
Geophys Res Lett. 2013 Dec 16;40(23):6033-6037. doi: 10.1002/2013GL057840. Epub 2013 Dec 09.

[1] The Sample Analysis at Mars (SAM) instrument suite on the Mars Science Laboratory (MSL) measured a Mars atmospheric

Clinical Presentation and Genetic Paradigm of Diffuse Infiltrating Retinoblastoma: A Review.

Ocular oncology and pathology

Traine PG, Schedler KJ, Rodrigues EB.
PMID: 27239450
Ocul Oncol Pathol. 2016 Apr;2(3):128-32. doi: 10.1159/000441528. Epub 2015 Nov 14.

Retinoblastoma is the most common childhood cancer. Thanks to modern technology and good medical access, mortality in Europe has decreased to about 5%. Diffuse infiltrating retinoblastoma is a very rare subtype of this neoplasm and is characterized by its...

CRYPTIC AND PSEUDO-CRYPTIC DIVERSITY IN DIATOMS-WITH DESCRIPTIONS OF PSEUDO-NITZSCHIA HASLEANA SP. NOV. AND P. FRYXELLIANA SP. NOV.(1).

Journal of phycology

Lundholm N, Bates SS, Baugh KA, Bill BD, Connell LB, Léger C, Trainer VL.
PMID: 27009733
J Phycol. 2012 Apr;48(2):436-54. doi: 10.1111/j.1529-8817.2012.01132.x. Epub 2012 Mar 19.

A high degree of pseudo-cryptic diversity was reported in the well-studied diatom genus Pseudo-nitzschia. Studies off the coast of Washington State revealed the presence of hitherto undescribed diversity of Pseudo-nitzschia. Forty-one clonal strains, representing six different taxa of the...

Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer.

ACS medicinal chemistry letters

Balog A, Rampulla R, Martin GS, Krystek SR, Attar R, Dell-John J, DiMarco JD, Fairfax D, Gougoutas J, Holst CL, Nation A, Rizzo C, Rossiter LM, Schweizer L, Shan W, Spergel S, Spires T, Cornelius G, Gottardis M, Trainor G, Vite GD, Salvati ME.
PMID: 26288692
ACS Med Chem Lett. 2015 Jun 19;6(8):908-12. doi: 10.1021/acsmedchemlett.5b00173. eCollection 2015 Aug 13.

BMS-641988 (23) is a novel, nonsteroidal androgen receptor antagonist designed for the treatment of prostate cancer. The compound has high binding affinity for the AR and acts as a functional antagonist in vitro. BMS-641988 is efficacious in multiple human...

Primordial argon isotope fractionation in the atmosphere of Mars measured by the SAM instrument on .

Geophysical research letters

Atreya SK, Trainer MG, Franz HB, Wong MH, Manning HL, Malespin CA, Mahaffy PR, Conrad PG, Brunner AE, Leshin LA, Jones JH, Webster CR, Owen TC, Pepin RO, Navarro-González R.
PMID: 25821261
Geophys Res Lett. 2013 Nov 16;40(21):5605-5609. doi: 10.1002/2013GL057763. Epub 2013 Nov 06.

[1] The quadrupole mass spectrometer of the Sample Analysis at Mars (SAM) instrument on

Serologic examination of wild birds for hemorrhagic enteritis of Turkey and marble spleen disease of pheasants.

Journal of wildlife diseases

Domermuth CH, Forrester DJ, Trainer DO, Bigler WJ.
PMID: 24228961
J Wildl Dis. 1977 Oct;13(4):405-8. doi: 10.7589/0090-3558-13.4.405.

Precipitin antibody which reacted with the hemorrhagic enteritis (HE) of turkeys/marble spleen disease (MSD) of pheasants group of avian adenoviruses, was not detected in serum samples of 618 wild birds (42 species) from Florida, Texas and Virginia. HE/MSD precipitin...

Tree shrews (Tupaia belangeri) exhibit novelty preference in the novel location memory task with 24-h retention periods.

Frontiers in psychology

Nair J, Topka M, Khani A, Isenschmid M, Rainer G.
PMID: 24782805
Front Psychol. 2014 Apr 14;5:303. doi: 10.3389/fpsyg.2014.00303. eCollection 2014.

Novelty preference is pervasive in mammalian species, and describes an inherent tendency to preferentially explore novelty. The novel location memory task studied here assesses the ability of animals to form accurate memories of a spatial configuration, consisting of several...

Showing 1 to 12 of 276 entries