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Showing 1 to 12 of 439 entries
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Development of nuclear and chloroplast microsatellite markers for the endangered conifer Callitris sulcata (Cupressaceae).

Applications in plant sciences

Sakaguchi S, Lannuzel G, Fogliani B, Wulff AS, L'Huillier L, Kurata S, Ueno S, Isagi Y, Tsumura Y, Ito M.
PMID: 26312198
Appl Plant Sci. 2015 Aug 10;3(8). doi: 10.3732/apps.1500045. eCollection 2015 Aug.

PREMISE OF THE STUDY: Microsatellite markers were developed for Callitris sulcata (Cupressaceae), an endangered conifer species in New Caledonia.METHODS AND RESULTS: Using sequencing by synthesis (SBS) of an RNA-Seq library, 15 polymorphic nuclear and chloroplast microsatellite markers were developed....

Daclatasvir and asunaprevir for genotype 1b chronic hepatitis C patients with chronic kidney disease.

Hepatology research : the official journal of the Japan Society of Hepatology

Kondo C, Atsukawa M, Tsubota A, Shimada N, Abe H, Asano T, Yoshizawa K, Okubo T, Chuganji Y, Aizawa Y, Iio E, Tanaka Y, Iwakiri K.
PMID: 28225572
Hepatol Res. 2017 Oct;47(11):1165-1173. doi: 10.1111/hepr.12879. Epub 2017 Apr 12.

AIM: To evaluate the efficacy and safety of daclatasvir and asunaprevir combined therapy in genotype 1b chronic hepatitis C patients with non-dialysis chronic kidney disease (CKD).METHODS: In a multicenter collaborative study, 249 patients received 60 mg daclatasvir (NS5A inhibitor)...

Assessment of the features of serum apolipoprotein profiles in chronic HCV infection: difference between HCV genotypes 1b and 2.

Hepatology international

Seki N, Sugita T, Aida Y, Itagaki M, Ishiguro H, Sutoh S, Abe H, Tsubota A, Matsushima M, Aizawa Y.
PMID: 26202760
Hepatol Int. 2014 Oct;8(4):550-9. doi: 10.1007/s12072-014-9572-2. Epub 2014 Sep 26.

BACKGROUND: The life cycle of hepatitis C virus (HCV) is tightly associated with host lipoprotein metabolic pathways. Apolipoprotein is present on the outer surface of lipoprotein particles and plays an important role in lipoprotein metabolism. We aimed to elucidate...

Stress-induced cortisol is associated with generation of non-negative interpretations during cognitive reappraisal.

BioPsychoSocial medicine

Tsumura H, Sensaki J, Shimada H.
PMID: 26550028
Biopsychosoc Med. 2015 Nov 07;9:23. doi: 10.1186/s13030-015-0049-x. eCollection 2015.

BACKGROUND: Enhanced processing of emotional stimuli after stress exposure is reported to be associated with stress-induced cortisol. Because enhanced emotional information processing could make cognitive emotion regulation more difficult, it was hypothesized that stress-induced cortisol would be associated with...

Efficacy of Alfacalcidol on PEG-IFN/ Ribavirin Combination Therapy for Elderly Patients With Chronic Hepatitis C: A Pilot Study.

Hepatitis monthly

Atsukawa M, Tsubota A, Shimada N, Kondo C, Itokawa N, Nakagawa A, Hashimoto S, Fukuda T, Matsushita Y, Kidokoro H, Narahara Y, Nakatsuka K, Iwakiri K, Kawamoto C, Sakamoto C.
PMID: 24403915
Hepat Mon. 2013 Dec 23;13(12):e14872. doi: 10.5812/hepatmon.14872. eCollection 2013.

BACKGROUND: Serum vitamin D concentration is reported to show a decrease in older age. Patients with chronic hepatitis C (CHC) in Japan are older on average than those in Western countries. Moreover, the outcome of pegylated-interferon (PEG-IFN)/ ribavirin therapy...

Genomics and Proteomics Provide New Insight into the Commensal and Pathogenic Lifestyles of Bovine- and Human-Associated Staphylococcus epidermidis Strains.

Journal of proteome research

Savijoki K, Iivanainen A, Siljamäki P, Laine PK, Paulin L, Karonen T, Pyörälä S, Kankainen M, Nyman TA, Salomäki T, Koskinen P, Holm L, Simojoki H, Taponen S, Sukura A, Kalkkinen N, Auvinen P, Varmanen P.
PMID: 25014494
J Proteome Res. 2014 Aug 01;13(8):3748-3762. doi: 10.1021/pr500322d. Epub 2014 Jul 18.

The present study reports comparative genomics and proteomics of Staphylococcus epidermidis (SE) strains isolated from bovine intramammary infection (PM221) and human hosts (ATCC12228 and RP62A). Genome-level profiling and protein expression analyses revealed that the bovine strain and the mildly...

DIFFERENTIATION OF MITOCHONDRIAL DNA POLYMORPHISMS IN POPULATIONS OF FIVE JAPANESE ABIES SPECIES.

Evolution; international journal of organic evolution

Tsumura Y, Suyama Y.
PMID: 28565202
Evolution. 1998 Aug;52(4):1031-1042. doi: 10.1111/j.1558-5646.1998.tb01831.x.

Mitochondrial DNA polymorphism of 40 populations of five Abies species was investigated using PCR-amplified coxI and coxIII gene probes. Using four combinations of probe and restriction enzyme, we detected three major haplotypes and 15 total haplotypes. We also found...

Autopsy results of a case of ingestion of sodium hydroxide solution.

Journal of toxicologic pathology

Emoto Y, Yoshizawa K, Shikata N, Tsubura A, Nagasaki Y.
PMID: 26989301
J Toxicol Pathol. 2016 Jan;29(1):45-7. doi: 10.1293/tox.2015-0049. Epub 2015 Sep 25.

Sodium hydroxide is a strongly corrosive alkali. We describe herein a case of suicide by ingestion of sodium hydroxide. A man in his 80s was found dead with a mug and a bottle of caustic soda. Macroscopically, liquefaction and/or...

A spontaneously occurring malignant ovarian Sertoli cell tumor in a young Sprague Dawley rat.

Journal of toxicologic pathology

Kinoshita Y, Yoshizawa K, Emoto Y, Yuki M, Yuri T, Shikata N, Elmore SA, Tsubura A.
PMID: 26989303
J Toxicol Pathol. 2016 Jan;29(1):53-9. doi: 10.1293/tox.2015-0057. Epub 2015 Nov 09.

Primary ovarian tumors are generally uncommon in rats used in toxicologic studies. A malignant Sertoli cell tumor was present in the ovary of a 19-week-old female Sprague Dawley rat. Macroscopically, the mass was white and firm, 10 × 13...

Green tea extract attenuates MNU-induced photoreceptor cell apoptosis via suppression of heme oxygenase-1.

Journal of toxicologic pathology

Emoto Y, Yoshizawa K, Kinoshita Y, Yuki M, Yuri T, Tsubura A.
PMID: 26989304
J Toxicol Pathol. 2016 Jan;29(1):61-5. doi: 10.1293/tox.2015-0052. Epub 2015 Oct 17.

The effects of green tea extract (GTE) on N-methyl-N-nitrosourea (MNU)-induced photoreceptor cell apoptosis were examined, and the possible mechanisms of action of GTE were assessed. Alterations in the retinal morphological architecture were determined by hematoxylin-eosin staining, vimentin immunoreactivity, and...

Dosimetry of permanent interstitial prostate brachytherapy for an interoperative procedure, using O-arm based CT and TRUS.

Journal of contemporary brachytherapy

Ishiyama H, Sekiguchi A, Satoh T, Tsumura H, Takenaka K, Kawakami S, Tabata K, Kobayashi K, Iwamura M, Hayakawa K.
PMID: 26985192
J Contemp Brachytherapy. 2016 Feb;8(1):7-16. doi: 10.5114/jcb.2016.57817. Epub 2016 Feb 09.

PURPOSE: The aim of this report is dosimetric evaluation for an intraoperative fusion computed tomography (CT) as a superior predictor of 1-month CT based dosimetry in comparison to transrectal ultrasound (TRUS) in permanent interstitial prostate brachytherapy.MATERIAL AND METHODS: Data...

Effect of native vitamin D3 supplementation on refractory chronic hepatitis C patients in simeprevir with pegylated interferon/ribavirin.

Hepatology research : the official journal of the Japan Society of Hepatology

Atsukawa M, Tsubota A, Shimada N, Yoshizawa K, Abe H, Asano T, Ohkubo Y, Araki M, Ikegami T, Okubo T, Kondo C, Osada Y, Nakatsuka K, Chuganji Y, Matsuzaki Y, Iwakiri K, Aizawa Y.
PMID: 26289410
Hepatol Res. 2016 Mar;46(5):450-8. doi: 10.1111/hepr.12575. Epub 2015 Sep 17.

AIM: Protease inhibitors with pegylated interferon (PEG IFN)/ribavirin improve a sustained virological response (SVR) rate to approximately 90% in chronic hepatitis C genotype 1b patients with IL28B rs8099917 genotype TT, but yield only approximately 50% in those with the...

Showing 1 to 12 of 439 entries