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A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles.

Case reports in neurological medicine

Nakamura K, Ago T, Tsuchimoto A, Noda N, Nakamura A, Ninomiya T, Uchiumi T, Tsuruya K, Kamouchi M, Ooboshi H, Kitazono T.
PMID: 25834748
Case Rep Neurol Med. 2015;2015:431461. doi: 10.1155/2015/431461. Epub 2015 Mar 09.

We herein report the finding of a 62-year-old male, who developed dysarthria and dysphagia, with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy- (CADASIL-) like cerebral lesions. He also suffered from slowly progressive renal failure with the findings...

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Nakamura K, Ago T, Tsuchimoto A, et al. A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles. Case Rep Neurol Med. 2015;2015:431461doi: 10.1155/2015/431461.
Nakamura, K., Ago, T., Tsuchimoto, A., Noda, N., Nakamura, A., Ninomiya, T., Uchiumi, T., Tsuruya, K., Kamouchi, M., Ooboshi, H., & Kitazono, T. (2015). A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles. Case reports in neurological medicine, 2015431461. https://doi.org/10.1155/2015/431461
Nakamura, Kuniyuki, et al. "A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles." Case reports in neurological medicine vol. 2015 (2015): 431461. doi: https://doi.org/10.1155/2015/431461
Nakamura K, Ago T, Tsuchimoto A, Noda N, Nakamura A, Ninomiya T, Uchiumi T, Tsuruya K, Kamouchi M, Ooboshi H, Kitazono T. A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles. Case Rep Neurol Med. 2015;2015:431461. doi: 10.1155/2015/431461. Epub 2015 Mar 09. PMID: 25834748; PMCID: PMC4365362.
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Integration of the temperate phage phiU into the putative tRNA gene on the chromosome of its host Rhizobium leguminosarum biovar trifolii.

The Journal of general and applied microbiology

Uchiumi T, Abe M, Higashi S.
PMID: 12501298
J Gen Appl Microbiol. 1998 Feb;44(1):93-99. doi: 10.2323/jgam.44.93.

The plasmid pCI6, carrying the attP site of the temperate phage phiU, integrates into the attB site on the chromosome of Rhizobium leguminosarum biovar trifolii strain 4S. The 4 kb EcoRI-HindIII region of pCI6 involved in site-specific integration was...

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Uchiumi T, Abe M, Higashi S. Integration of the temperate phage phiU into the putative tRNA gene on the chromosome of its host Rhizobium leguminosarum biovar trifolii. J Gen Appl Microbiol. 1998;44(1):93-99doi: 10.2323/jgam.44.93.
Uchiumi, T., Abe, M., & Higashi, S. (1998). Integration of the temperate phage phiU into the putative tRNA gene on the chromosome of its host Rhizobium leguminosarum biovar trifolii. The Journal of general and applied microbiology, 44(1), 93-99. https://doi.org/10.2323/jgam.44.93
Uchiumi, Toshiki, et al. "Integration of the temperate phage phiU into the putative tRNA gene on the chromosome of its host Rhizobium leguminosarum biovar trifolii." The Journal of general and applied microbiology vol. 44,1 (1998): 93-99. doi: https://doi.org/10.2323/jgam.44.93
Uchiumi T, Abe M, Higashi S. Integration of the temperate phage phiU into the putative tRNA gene on the chromosome of its host Rhizobium leguminosarum biovar trifolii. J Gen Appl Microbiol. 1998 Feb;44(1):93-99. doi: 10.2323/jgam.44.93. PMID: 12501298.
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Pumping configuration without focusing lenses for a small-sized diode-pumped Nd:YAG slab laser.

Optics letters

Ishimori A, Yamamoto T, Uchiumi T, Yagi S, Shigihara K.
PMID: 19784223
Opt Lett. 1992 Jan 01;17(1):40-2. doi: 10.1364/ol.17.000040.

We propose an end-pumping method for a small-sized diode-pumped Nd:YAG laser. The miniature Nd:YAG slab is directly coupled to the pump diode without focusing lenses. With the use of total reflection on the slab surfaces, the pump light is...

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Ishimori A, Yamamoto T, Uchiumi T, et al. Pumping configuration without focusing lenses for a small-sized diode-pumped Nd:YAG slab laser. Opt Lett. 1992;17(1):40-2doi: 10.1364/ol.17.000040.
Ishimori, A., Yamamoto, T., Uchiumi, T., Yagi, S., & Shigihara, K. (1992). Pumping configuration without focusing lenses for a small-sized diode-pumped Nd:YAG slab laser. Optics letters, 17(1), 40-2. https://doi.org/10.1364/ol.17.000040
Ishimori, A, et al. "Pumping configuration without focusing lenses for a small-sized diode-pumped Nd:YAG slab laser." Optics letters vol. 17,1 (1992): 40-2. doi: https://doi.org/10.1364/ol.17.000040
Ishimori A, Yamamoto T, Uchiumi T, Yagi S, Shigihara K. Pumping configuration without focusing lenses for a small-sized diode-pumped Nd:YAG slab laser. Opt Lett. 1992 Jan 01;17(1):40-2. doi: 10.1364/ol.17.000040. PMID: 19784223.
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A rapid enzyme immunoassay for cholectystokinin octapeptide sulfate.

Neurochemistry international

Takeda K, Uchiumi F, Takita M, Kato T.
PMID: 20504465
Neurochem Int. 1989;15(1):55-60. doi: 10.1016/0197-0186(89)90076-4.

A rapid and sensitive enzyme immunoassay (EIA) for cholecystokinin octapeptide sulfate (CCK-8S) has been developed. The assay is based on a double antibody method using N-terminal specific antibody to CCK-8S, and CCK-8S conjugated with horseradish peroxidase as the enzyme...

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Takeda K, Uchiumi F, Takita M, et al. A rapid enzyme immunoassay for cholectystokinin octapeptide sulfate. Neurochem Int. 1989;15(1):55-60doi: 10.1016/0197-0186(89)90076-4.
Takeda, K., Uchiumi, F., Takita, M., & Kato, T. (1989). A rapid enzyme immunoassay for cholectystokinin octapeptide sulfate. Neurochemistry international, 15(1), 55-60. https://doi.org/10.1016/0197-0186(89)90076-4
Takeda, K, et al. "A rapid enzyme immunoassay for cholectystokinin octapeptide sulfate." Neurochemistry international vol. 15,1 (1989): 55-60. doi: https://doi.org/10.1016/0197-0186(89)90076-4
Takeda K, Uchiumi F, Takita M, Kato T. A rapid enzyme immunoassay for cholectystokinin octapeptide sulfate. Neurochem Int. 1989;15(1):55-60. doi: 10.1016/0197-0186(89)90076-4. PMID: 20504465.
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Downregulation of keratins 8, 18 and 19 influences invasiveness of human cultured squamous cell carcinoma and adenocarcinoma cells.

Experimental and therapeutic medicine

Uchiumi A, Yamashita M, Katagata Y.
PMID: 22969909
Exp Ther Med. 2012 Mar;3(3):443-448. doi: 10.3892/etm.2011.413. Epub 2011 Dec 09.

Keratin (K) expression index has been reported to be related to cell invasion activity in adenocarcinoma. In a previous study, we observed a negative correlation between K expression and cell invasion activity; i.e., when many Ks are expressed in...

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Uchiumi A, Yamashita M, Katagata Y. Downregulation of keratins 8, 18 and 19 influences invasiveness of human cultured squamous cell carcinoma and adenocarcinoma cells. Exp Ther Med. 2011;3(3):443-448doi: 10.3892/etm.2011.413.
Uchiumi, A., Yamashita, M., & Katagata, Y. (2012). Downregulation of keratins 8, 18 and 19 influences invasiveness of human cultured squamous cell carcinoma and adenocarcinoma cells. Experimental and therapeutic medicine, 3(3), 443-448. https://doi.org/10.3892/etm.2011.413
Uchiumi, A, et al. "Downregulation of keratins 8, 18 and 19 influences invasiveness of human cultured squamous cell carcinoma and adenocarcinoma cells." Experimental and therapeutic medicine vol. 3,3 (2012): 443-448. doi: https://doi.org/10.3892/etm.2011.413
Uchiumi A, Yamashita M, Katagata Y. Downregulation of keratins 8, 18 and 19 influences invasiveness of human cultured squamous cell carcinoma and adenocarcinoma cells. Exp Ther Med. 2012 Mar;3(3):443-448. doi: 10.3892/etm.2011.413. Epub 2011 Dec 09. PMID: 22969909; PMCID: PMC3438849.
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Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer.

Frontiers in pharmacology

Kosgodage US, Mould R, Henley AB, Nunn AV, Guy GW, Thomas EL, Inal JM, Bell JD, Lange S.
PMID: 30150937
Front Pharmacol. 2018 Aug 13;9:889. doi: 10.3389/fphar.2018.00889. eCollection 2018.

Exosomes and microvesicles (EMV) are lipid bilayer-enclosed structures, released by cells and involved in intercellular communication through transfer of proteins and genetic material. EMV release is also associated with various pathologies, including cancer, where increased EMV release is amongst...

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Kosgodage US, Mould R, Henley AB, et al. Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Front Pharmacol. 2018;9:889doi: 10.3389/fphar.2018.00889.
Kosgodage, U. S., Mould, R., Henley, A. B., Nunn, A. V., Guy, G. W., Thomas, E. L., Inal, J. M., Bell, J. D., & Lange, S. (2018). Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Frontiers in pharmacology, 9889. https://doi.org/10.3389/fphar.2018.00889
Kosgodage, Uchini S, et al. "Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer." Frontiers in pharmacology vol. 9 (2018): 889. doi: https://doi.org/10.3389/fphar.2018.00889
Kosgodage US, Mould R, Henley AB, Nunn AV, Guy GW, Thomas EL, Inal JM, Bell JD, Lange S. Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Front Pharmacol. 2018 Aug 13;9:889. doi: 10.3389/fphar.2018.00889. eCollection 2018. PMID: 30150937; PMCID: PMC6099119.
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The close association of pi-class glutathione S-transferase with drug sensitivity to alkylating agents and cisplatin in human cancer cells.

International journal of oncology

Tanaka T, Yokomizo A, Uchiumi T, Furukawa M, Wada M, Kuwano M.
PMID: 21533477
Int J Oncol. 1997 May;10(5):1009-14. doi: 10.3892/ijo.10.5.1009.

Buthionine sulfoximine (BSO) is a synthetic amino acid that irreversibly inhibits glutathione biosynthesis. A BSO-resistant line, KB/BSO3, was established from human epidermoid cancer KB cells; and other BSO-resistant lines, HLE/BSO1 and HLE/BSO2, were from human hepatic cancer HLE cells....

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Tanaka T, Yokomizo A, Uchiumi T, et al. The close association of pi-class glutathione S-transferase with drug sensitivity to alkylating agents and cisplatin in human cancer cells. Int J Oncol. 1997;10(5):1009-14doi: 10.3892/ijo.10.5.1009.
Tanaka, T., Yokomizo, A., Uchiumi, T., Furukawa, M., Wada, M., & Kuwano, M. (1997). The close association of pi-class glutathione S-transferase with drug sensitivity to alkylating agents and cisplatin in human cancer cells. International journal of oncology, 10(5), 1009-14. https://doi.org/10.3892/ijo.10.5.1009
Tanaka, T, et al. "The close association of pi-class glutathione S-transferase with drug sensitivity to alkylating agents and cisplatin in human cancer cells." International journal of oncology vol. 10,5 (1997): 1009-14. doi: https://doi.org/10.3892/ijo.10.5.1009
Tanaka T, Yokomizo A, Uchiumi T, Furukawa M, Wada M, Kuwano M. The close association of pi-class glutathione S-transferase with drug sensitivity to alkylating agents and cisplatin in human cancer cells. Int J Oncol. 1997 May;10(5):1009-14. doi: 10.3892/ijo.10.5.1009. PMID: 21533477.
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Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey.

International journal of environmental research and public health

Sugaya N, Yamamoto T, Suzuki N, Uchiumi C.
PMID: 34948939
Int J Environ Res Public Health. 2021 Dec 17;18(24). doi: 10.3390/ijerph182413318.

We conducted a large-scale survey in the Japanese population, about one year after the initial declaration of the state of emergency, to investigate alcohol use under the prolonged coronavirus disease 2019 (COVID-19) pandemic and its related psychosocial and demographic...

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Sugaya N, Yamamoto T, Suzuki N, et al. Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey. Int J Environ Res Public Health. 2021;18(24)doi: 10.3390/ijerph182413318.
Sugaya, N., Yamamoto, T., Suzuki, N., & Uchiumi, C. (2021). Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey. International journal of environmental research and public health, 18(24), . https://doi.org/10.3390/ijerph182413318
Sugaya, Nagisa, et al. "Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey." International journal of environmental research and public health vol. 18,24 (2021). doi: https://doi.org/10.3390/ijerph182413318
Sugaya N, Yamamoto T, Suzuki N, Uchiumi C. Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey. Int J Environ Res Public Health. 2021 Dec 17;18(24). doi: 10.3390/ijerph182413318. PMID: 34948939.
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Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix.

Communications biology

Matsushima Y, Takahashi K, Yue S, Fujiyoshi Y, Yoshioka H, Aihara M, Setoyama D, Uchiumi T, Fukuchi S, Kang D.
PMID: 34400774
Commun Biol. 2021 Aug 16;4(1):974. doi: 10.1038/s42003-021-02498-z.

Human ATP-dependent Lon protease (LONP1) forms homohexameric, ring-shaped complexes. Depletion of LONP1 causes aggregation of a broad range of proteins in the mitochondrial matrix and decreases the levels of their soluble forms. The ATP hydrolysis activity, but not protease...

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Matsushima Y, Takahashi K, Yue S, et al. Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix. Commun Biol. 2021;4(1):974doi: 10.1038/s42003-021-02498-z.
Matsushima, Y., Takahashi, K., Yue, S., Fujiyoshi, Y., Yoshioka, H., Aihara, M., Setoyama, D., Uchiumi, T., Fukuchi, S., & Kang, D. (2021). Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix. Communications biology, 4(1), 974. https://doi.org/10.1038/s42003-021-02498-z
Matsushima, Yuichi, et al. "Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix." Communications biology vol. 4,1 (2021): 974. doi: https://doi.org/10.1038/s42003-021-02498-z
Matsushima Y, Takahashi K, Yue S, Fujiyoshi Y, Yoshioka H, Aihara M, Setoyama D, Uchiumi T, Fukuchi S, Kang D. Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix. Commun Biol. 2021 Aug 16;4(1):974. doi: 10.1038/s42003-021-02498-z. PMID: 34400774; PMCID: PMC8368198.
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Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance.

mSphere

Yoshino M, Aihara M, Gotoh Y, Akimoto M, Tatsuhara W, Kiyosuke M, Matsushima Y, Uchiumi T, Hayashi T, Kang D.
PMID: 34817239
mSphere. 2021 Nov 24;e0073421. doi: 10.1128/mSphere.00734-21. Epub 2021 Nov 24.

Five

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Yoshino M, Aihara M, Gotoh Y, et al. Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance. mSphere. 2021;e0073421doi: 10.1128/mSphere.00734-21.
Yoshino, M., Aihara, M., Gotoh, Y., Akimoto, M., Tatsuhara, W., Kiyosuke, M., Matsushima, Y., Uchiumi, T., Hayashi, T., & Kang, D. (2021). Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance. mSphere, e0073421. https://doi.org/10.1128/mSphere.00734-21
Yoshino, Mai, et al. "Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance." mSphere vol. (2021): e0073421. doi: https://doi.org/10.1128/mSphere.00734-21
Yoshino M, Aihara M, Gotoh Y, Akimoto M, Tatsuhara W, Kiyosuke M, Matsushima Y, Uchiumi T, Hayashi T, Kang D. Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance. mSphere. 2021 Nov 24;e0073421. doi: 10.1128/mSphere.00734-21. Epub 2021 Nov 24. PMID: 34817239; PMCID: PMC8612250.
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Expression of soybean plant hemoglobin gene family under abiotic stresses.

Plant biotechnology (Tokyo, Japan)

Araragi M, Ikeura A, Uchiumi T.
PMID: 34177321
Plant Biotechnol (Tokyo). 2021 Mar 25;38(1):23-30. doi: 10.5511/plantbiotechnology.20.0907a.

Many abiotic stresses induce the generation of nitric oxide (NO) in plant tissues, where it functions as a signal molecule in stress responses. Plants modulate NO by oxidizing it to NO

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Araragi M, Ikeura A, Uchiumi T. Expression of soybean plant hemoglobin gene family under abiotic stresses. Plant Biotechnol (Tokyo). 2021;38(1):23-30doi: 10.5511/plantbiotechnology.20.0907a.
Araragi, M., Ikeura, A., & Uchiumi, T. (2021). Expression of soybean plant hemoglobin gene family under abiotic stresses. Plant biotechnology (Tokyo, Japan), 38(1), 23-30. https://doi.org/10.5511/plantbiotechnology.20.0907a
Araragi, Masato, et al. "Expression of soybean plant hemoglobin gene family under abiotic stresses." Plant biotechnology (Tokyo, Japan) vol. 38,1 (2021): 23-30. doi: https://doi.org/10.5511/plantbiotechnology.20.0907a
Araragi M, Ikeura A, Uchiumi T. Expression of soybean plant hemoglobin gene family under abiotic stresses. Plant Biotechnol (Tokyo). 2021 Mar 25;38(1):23-30. doi: 10.5511/plantbiotechnology.20.0907a. PMID: 34177321; PMCID: PMC8215466.
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Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey.

International journal of environmental research and public health

Sugaya N, Yamamoto T, Suzuki N, Uchiumi C.
PMID: 34948939
Int J Environ Res Public Health. 2021 Dec 17;18(24). doi: 10.3390/ijerph182413318.

We conducted a large-scale survey in the Japanese population, about one year after the initial declaration of the state of emergency, to investigate alcohol use under the prolonged coronavirus disease 2019 (COVID-19) pandemic and its related psychosocial and demographic...

Cite
Sugaya N, Yamamoto T, Suzuki N, et al. Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey. Int J Environ Res Public Health. 2021;18(24)doi: 10.3390/ijerph182413318.
Sugaya, N., Yamamoto, T., Suzuki, N., & Uchiumi, C. (2021). Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey. International journal of environmental research and public health, 18(24), . https://doi.org/10.3390/ijerph182413318
Sugaya, Nagisa, et al. "Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey." International journal of environmental research and public health vol. 18,24 (2021). doi: https://doi.org/10.3390/ijerph182413318
Sugaya N, Yamamoto T, Suzuki N, Uchiumi C. Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey. Int J Environ Res Public Health. 2021 Dec 17;18(24). doi: 10.3390/ijerph182413318. PMID: 34948939; PMCID: PMC8707504.
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Showing 1 to 12 of 67 entries