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Showing 1 to 12 of 61 entries
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Differential myofiber-type transduction preference of adeno-associated virus serotypes 6 and 9.

Skeletal muscle

Riaz M, Raz Y, Moloney EB, van Putten M, Krom YD, van der Maarel SM, Verhaagen J, Raz V.
PMID: 26561520
Skelet Muscle. 2015 Nov 10;5:37. doi: 10.1186/s13395-015-0064-4. eCollection 2015.

BACKGROUND: Gene therapy strategies are promising therapeutic options for monogenic muscular dystrophies, with several currently underways. The adeno-associated viral (AAV) vector is among the most effective gene delivery systems. However, transduction efficiency in skeletal muscles varies between AAV serotypes,...

Concerning Acquisitions in Lane Medical Library.

California and western medicine

van Patten N.
PMID: 18745774
Cal West Med. 1940 Nov;53(5):250.

No abstract available.

Insights into the pore of the hair cell transducer channel from experiments with permeant blockers.

Current topics in membranes

van Netten SM, Kros CJ.
PMID: 25168143
Curr Top Membr. 2007;59:375-98. doi: 10.1016/S1063-5823(06)59013-1. Epub 2007 Apr 17.

This chapter presents recent experiments designed to infer the properties of the ion-conducting pore of the mechanoelectrical transducer channel of sensory hair cells using permeant blockers. By combining results from experiments with three classes of large cationic permeant blockers,...

Suppression of the fibrotic encapsulation of silicone implants by inhibiting the mechanical activation of pro-fibrotic TGF-β.

Nature biomedical engineering

Noskovicova N, Schuster R, van Putten S, Ezzo M, Koehler A, Boo S, Coelho NM, Griggs D, Ruminski P, McCulloch CA, Hinz B.
PMID: 34031559
Nat Biomed Eng. 2021 Dec;5(12):1437-1456. doi: 10.1038/s41551-021-00722-z. Epub 2021 May 24.

The fibrotic encapsulation of implants involves the mechanical activation of myofibroblasts and of pro-fibrotic transforming growth factor beta 1 (TGF-β1). Here, we show that both softening of the implant surfaces and inhibition of the activation of TGF-β1 reduce the...

Rapid and Sensitive Identification and Discrimination of Bound/Unbound Ligands on Colloidal Nanocrystals via Direct Analysis in Real-Time Mass Spectrometry.

Langmuir : the ACS journal of surfaces and colloids

Frazier J, Cavey K, Coil S, Hamo H, Zhang M, Van Patten PG.
PMID: 34879204
Langmuir. 2021 Dec 08; doi: 10.1021/acs.langmuir.1c02548. Epub 2021 Dec 08.

Direct analysis in real-time mass spectrometry (DART-MS) has been applied to the characterization of colloidal nanocrystal surface ligands. The nanocrystals (NCs) in colloidal suspension were purified and deposited onto a solid substrate, and the solvent was allowed to evaporate....

A de novo .

International medical case reports journal

Verhoeven WMA, Egger JIM, Jongbloed RE, van Putten MM, de Bruin-van Zandwijk M, Zwemer AS, Pfundt R, Willemsen MH.
PMID: 33116939
Int Med Case Rep J. 2020 Oct 07;13:487-492. doi: 10.2147/IMCRJ.S270487. eCollection 2020.

The catenin beta-1 (

REM Sleep Behavior Disorder in Parkinson's Disease: Change in Cognitive, Psychiatric, and Functional Outcomes from Baseline to 16-47-Month Follow-Up.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Van Patten R, Mahmood Z, Pickell D, Maye JE, Roesch S, Twamley EW, Filoteo JV, Schiehser DM.
PMID: 34037689
Arch Clin Neuropsychol. 2022 Jan 17;37(1):1-11. doi: 10.1093/arclin/acab037.

OBJECTIVE: Rapid Eye Movement Sleep Behavior Disorder (RBD) is common in Parkinson's Disease (PD) and is associated with cognitive impairment; however, the majority of the evidence on the impact of RBD on multidomain cognitive batteries in PD is cross-sectional....

Preclinical studies on intestinal administration of antisense oligonucleotides as a model for oral delivery for treatment of duchenne muscular dystrophy.

Molecular therapy. Nucleic acids

van Putten M, Young C, van den Berg S, Pronk A, Hulsker M, Karnaoukh TG, Vermue R, van Dijk KW, de Kimpe S, Aartsma-Rus A.
PMID: 25405468
Mol Ther Nucleic Acids. 2014 Nov 18;3:e211. doi: 10.1038/mtna.2014.62.

Antisense oligonucleotides (AONs) used to reframe dystrophin mRNA transcripts for Duchenne muscular dystrophy (DMD) patients are tested in clinical trials. Here, AONs are administered subcutaneously and intravenously, while the less invasive oral route would be preferred. Oral delivery of...

A review of gambling disorder and substance use disorders.

Substance abuse and rehabilitation

Rash CJ, Weinstock J, Van Patten R.
PMID: 27051333
Subst Abuse Rehabil. 2016 Mar 17;7:3-13. doi: 10.2147/SAR.S83460. eCollection 2016.

In the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), gambling disorder was recategorized from the "Impulse Control Disorder" section to the newly expanded "Substance-related and Addictive Disorders" section. With this move, gambling disorder has...

d-Tubocurarine and Berbamine: Alkaloids That Are Permeant Blockers of the Hair Cell's Mechano-Electrical Transducer Channel and Protect from Aminoglycoside Toxicity.

Frontiers in cellular neuroscience

Kirkwood NK, O'Reilly M, Derudas M, Kenyon EJ, Huckvale R, van Netten SM, Ward SE, Richardson GP, Kros CJ.
PMID: 28928635
Front Cell Neurosci. 2017 Sep 05;11:262. doi: 10.3389/fncel.2017.00262. eCollection 2017.

Aminoglycoside antibiotics are widely used for the treatment of life-threatening bacterial infections, but cause permanent hearing loss in a substantial proportion of treated patients. The sensory hair cells of the inner ear are damaged following entry of these antibiotics...

Training Can Increase Students' Choices for Written Solution Strategies and Performance in Solving Multi-Digit Division Problems.

Frontiers in psychology

Fagginger Auer MF, Hickendorff M, van Putten CM.
PMID: 30258375
Front Psychol. 2018 Sep 11;9:1644. doi: 10.3389/fpsyg.2018.01644. eCollection 2018.

Making adaptive choices between solution strategies is a central element of contemporary mathematics education. However, previous studies signal that students make suboptimal choices between mental and written strategies to solve division problems. In particular, some students of a lower...

EDITORIAL NOTE.

Bulletin of the Medical Library Association

Van Patten N.
PMID: 16015991
Bull Med Libr Assoc. 1926 Jul;16(1):45-6.

No abstract available.

Showing 1 to 12 of 61 entries