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Showing 1 to 12 of 157 entries
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The interactive web-based program MSmonitor for self-management and multidisciplinary care in multiple sclerosis: concept, content, and pilot results.

Patient preference and adherence

Jongen PJ, Sinnige LG, van Geel BM, Verheul F, Verhagen WI, van der Kruijk RA, Haverkamp R, Schrijver HM, Baart JC, Visser LH, Arnoldus EP, Gilhuis HJ, Pop P, Booy M, Lemmens W, Donders R, Kool A, van Noort E.
PMID: 26715841
Patient Prefer Adherence. 2015 Dec 11;9:1741-50. doi: 10.2147/PPA.S93783. eCollection 2015.

BACKGROUND: There is a growing need to offer persons with multiple sclerosis (PwMS) possibilities for self-management and to integrate multidisciplinary health data. In 2009-2014 we developed a patient-reported outcome based, interactive, web-based program (MSmonitor) for (self-)monitoring, self-management and integrated,...

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Jongen PJ, Sinnige LG, van Geel BM, et al. The interactive web-based program MSmonitor for self-management and multidisciplinary care in multiple sclerosis: concept, content, and pilot results. Patient Prefer Adherence. 2015;9:1741-50doi: 10.2147/PPA.S93783.
Jongen, P. J., Sinnige, L. G., van Geel, B. M., Verheul, F., Verhagen, W. I., van der Kruijk, R. A., Haverkamp, R., Schrijver, H. M., Baart, J. C., Visser, L. H., Arnoldus, E. P., Gilhuis, H. J., Pop, P., Booy, M., Lemmens, W., Donders, R., Kool, A., & van Noort, E. (2015). The interactive web-based program MSmonitor for self-management and multidisciplinary care in multiple sclerosis: concept, content, and pilot results. Patient preference and adherence, 91741-50. https://doi.org/10.2147/PPA.S93783
Jongen, Peter Joseph, et al. "The interactive web-based program MSmonitor for self-management and multidisciplinary care in multiple sclerosis: concept, content, and pilot results." Patient preference and adherence vol. 9 (2015): 1741-50. doi: https://doi.org/10.2147/PPA.S93783
Jongen PJ, Sinnige LG, van Geel BM, Verheul F, Verhagen WI, van der Kruijk RA, Haverkamp R, Schrijver HM, Baart JC, Visser LH, Arnoldus EP, Gilhuis HJ, Pop P, Booy M, Lemmens W, Donders R, Kool A, van Noort E. The interactive web-based program MSmonitor for self-management and multidisciplinary care in multiple sclerosis: concept, content, and pilot results. Patient Prefer Adherence. 2015 Dec 11;9:1741-50. doi: 10.2147/PPA.S93783. eCollection 2015. PMID: 26715841; PMCID: PMC4685885.
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Novel drugs that target the metabolic reprogramming in renal cell cancer.

Cancer & metabolism

van der Mijn JC, Panka DJ, Geissler AK, Verheul HM, Mier JW.
PMID: 27418963
Cancer Metab. 2016 Jul 13;4:14. doi: 10.1186/s40170-016-0154-8. eCollection 2016.

Molecular profiling studies of tumor tissue from patients with clear cell renal cell cancer (ccRCC) have revealed extensive metabolic reprogramming in this disease. Associations were found between metabolic reprogramming, histopathologic Fuhrman grade, and overall survival of patients. Large-scale genomics,...

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van der Mijn JC, Panka DJ, Geissler AK, et al. Novel drugs that target the metabolic reprogramming in renal cell cancer. Cancer Metab. 2016;4:14doi: 10.1186/s40170-016-0154-8.
van der Mijn, J. C., Panka, D. J., Geissler, A. K., Verheul, H. M., & Mier, J. W. (2016). Novel drugs that target the metabolic reprogramming in renal cell cancer. Cancer & metabolism, 414. https://doi.org/10.1186/s40170-016-0154-8
van der Mijn, Johannes C, et al. "Novel drugs that target the metabolic reprogramming in renal cell cancer." Cancer & metabolism vol. 4 (2016): 14. doi: https://doi.org/10.1186/s40170-016-0154-8
van der Mijn JC, Panka DJ, Geissler AK, Verheul HM, Mier JW. Novel drugs that target the metabolic reprogramming in renal cell cancer. Cancer Metab. 2016 Jul 13;4:14. doi: 10.1186/s40170-016-0154-8. eCollection 2016. PMID: 27418963; PMCID: PMC4944519.
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[No title available]

Frontiers in immunology

Veluchamy JP, Lopez-Lastra S, Spanholtz J, Bohme F, Kok N, Heideman DA, Verheul HM, Di Santo JP, de Gruijl TD, van der Vliet HJ.
PMID: 28220124
Front Immunol. 2017 Feb 06;8:87. doi: 10.3389/fimmu.2017.00087. eCollection 2017.

Therapeutic monoclonal antibodies against the epidermal growth factor receptor (EGFR) act by inhibiting EGFR downstream signaling and by eliciting a natural killer (NK) cell-mediated antitumor response. The IgG

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Veluchamy JP, Lopez-Lastra S, Spanholtz J, et al. . Front Immunol. 2017;8:87doi: 10.3389/fimmu.2017.00087.
Veluchamy, J. P., Lopez-Lastra, S., Spanholtz, J., Bohme, F., Kok, N., Heideman, D. A., Verheul, H. M., Di Santo, J. P., de Gruijl, T. D., & van der Vliet, H. J. (2017). . Frontiers in immunology, 887. https://doi.org/10.3389/fimmu.2017.00087
Veluchamy, John P, et al. "." Frontiers in immunology vol. 8 (2017): 87. doi: https://doi.org/10.3389/fimmu.2017.00087
Veluchamy JP, Lopez-Lastra S, Spanholtz J, Bohme F, Kok N, Heideman DA, Verheul HM, Di Santo JP, de Gruijl TD, van der Vliet HJ. . Front Immunol. 2017 Feb 06;8:87. doi: 10.3389/fimmu.2017.00087. eCollection 2017. PMID: 28220124; PMCID: PMC5292674.
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Connexin diversity in the heart: insights from transgenic mouse models.

Frontiers in pharmacology

Verheule S, Kaese S.
PMID: 23818881
Front Pharmacol. 2013 Jun 27;4:81. doi: 10.3389/fphar.2013.00081. Print 2013.

Cardiac conduction is mediated by gap junction channels that are formed by connexin (Cx) protein subunits. The connexin family of proteins consists of more than 20 members varying in their biophysical properties and ability to combine with other connexins...

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Verheule S, Kaese S. Connexin diversity in the heart: insights from transgenic mouse models. Front Pharmacol. 2013;4:81doi: 10.3389/fphar.2013.00081.
Verheule, S., & Kaese, S. (2013). Connexin diversity in the heart: insights from transgenic mouse models. Frontiers in pharmacology, 481. https://doi.org/10.3389/fphar.2013.00081
Verheule, Sander, and Kaese, Sven. "Connexin diversity in the heart: insights from transgenic mouse models." Frontiers in pharmacology vol. 4 (2013): 81. doi: https://doi.org/10.3389/fphar.2013.00081
Verheule S, Kaese S. Connexin diversity in the heart: insights from transgenic mouse models. Front Pharmacol. 2013 Jun 27;4:81. doi: 10.3389/fphar.2013.00081. Print 2013. PMID: 23818881; PMCID: PMC3694209.
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The V-line: a sonographic aid for the confirmation of pleural fluid.

Critical ultrasound journal

Atkinson P, Milne J, Loubani O, Verheul G.
PMID: 22920298
Crit Ultrasound J. 2012 Aug 24;4(1):19. doi: 10.1186/2036-7902-4-19.

BACKGROUND: Ultrasound is being used increasingly to diagnose pathological free fluid accumulation at the bedside. In addition to the detection of peritoneal and pericardial fluid, point-of-care ultrasound allows rapid bedside diagnosis of pleural fluid.FINDINGS: In this short report, we...

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Atkinson P, Milne J, Loubani O, et al. The V-line: a sonographic aid for the confirmation of pleural fluid. Crit Ultrasound J. 2012;4(1):19doi: 10.1186/2036-7902-4-19.
Atkinson, P., Milne, J., Loubani, O., & Verheul, G. (2012). The V-line: a sonographic aid for the confirmation of pleural fluid. Critical ultrasound journal, 4(1), 19. https://doi.org/10.1186/2036-7902-4-19
Atkinson, Paul, et al. "The V-line: a sonographic aid for the confirmation of pleural fluid." Critical ultrasound journal vol. 4,1 (2012): 19. doi: https://doi.org/10.1186/2036-7902-4-19
Atkinson P, Milne J, Loubani O, Verheul G. The V-line: a sonographic aid for the confirmation of pleural fluid. Crit Ultrasound J. 2012 Aug 24;4(1):19. doi: 10.1186/2036-7902-4-19. PMID: 22920298; PMCID: PMC3480906.
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Loss of Side-to-Side Connections Affects the Relative Contributions of the Sodium and Calcium Current to Transverse Propagation Between Strands of Atrial Myocytes.

Frontiers in physiology

Zhao J, Schotten U, Smaill B, Verheule S.
PMID: 30233394
Front Physiol. 2018 Sep 04;9:1212. doi: 10.3389/fphys.2018.01212. eCollection 2018.

No abstract available.

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Zhao J, Schotten U, Smaill B, et al. Loss of Side-to-Side Connections Affects the Relative Contributions of the Sodium and Calcium Current to Transverse Propagation Between Strands of Atrial Myocytes. Front Physiol. 2018;9:1212doi: 10.3389/fphys.2018.01212.
Zhao, J., Schotten, U., Smaill, B., & Verheule, S. (2018). Loss of Side-to-Side Connections Affects the Relative Contributions of the Sodium and Calcium Current to Transverse Propagation Between Strands of Atrial Myocytes. Frontiers in physiology, 91212. https://doi.org/10.3389/fphys.2018.01212
Zhao, Jichao, et al. "Loss of Side-to-Side Connections Affects the Relative Contributions of the Sodium and Calcium Current to Transverse Propagation Between Strands of Atrial Myocytes." Frontiers in physiology vol. 9 (2018): 1212. doi: https://doi.org/10.3389/fphys.2018.01212
Zhao J, Schotten U, Smaill B, Verheule S. Loss of Side-to-Side Connections Affects the Relative Contributions of the Sodium and Calcium Current to Transverse Propagation Between Strands of Atrial Myocytes. Front Physiol. 2018 Sep 04;9:1212. doi: 10.3389/fphys.2018.01212. eCollection 2018. PMID: 30233394; PMCID: PMC6131618.
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Phase I Study of Dalteparin in Combination With Sunitinib in Patients With Metastatic Clear Cell Renal Carcinoma.

Clinical genitourinary cancer

Wentink MQ, Verheul HMW, Pal SK, George S, Voortman J, Danchaivijitr P, Adelaiye R, Poslinski D, Groman A, Hutson A, Pili R.
PMID: 28781191
Clin Genitourin Cancer. 2017 Jul 14; doi: 10.1016/j.clgc.2017.07.004. Epub 2017 Jul 14.

BACKGROUND: Based on the tumor-driven concomitant activation of angiogenesis and coagulation we conducted a phase I combination study of sunitinib with the low molecular weight heparin dalteparin in patients with metastatic clear cell renal cell carcinoma (ccRCC).MATERIALS AND METHODS:...

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Wentink MQ, Verheul HMW, Pal SK, et al. Phase I Study of Dalteparin in Combination With Sunitinib in Patients With Metastatic Clear Cell Renal Carcinoma. Clin Genitourin Cancer. 2017;doi: 10.1016/j.clgc.2017.07.004.
Wentink, M. Q., Verheul, H. M. W., Pal, S. K., George, S., Voortman, J., Danchaivijitr, P., Adelaiye, R., Poslinski, D., Groman, A., Hutson, A., & Pili, R. (2017). Phase I Study of Dalteparin in Combination With Sunitinib in Patients With Metastatic Clear Cell Renal Carcinoma. Clinical genitourinary cancer, . https://doi.org/10.1016/j.clgc.2017.07.004
Wentink, Madelon Q, et al. "Phase I Study of Dalteparin in Combination With Sunitinib in Patients With Metastatic Clear Cell Renal Carcinoma." Clinical genitourinary cancer vol. (2017). doi: https://doi.org/10.1016/j.clgc.2017.07.004
Wentink MQ, Verheul HMW, Pal SK, George S, Voortman J, Danchaivijitr P, Adelaiye R, Poslinski D, Groman A, Hutson A, Pili R. Phase I Study of Dalteparin in Combination With Sunitinib in Patients With Metastatic Clear Cell Renal Carcinoma. Clin Genitourin Cancer. 2017 Jul 14; doi: 10.1016/j.clgc.2017.07.004. Epub 2017 Jul 14. PMID: 28781191.
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Iatrogenic cortical pseudoaneurysm following ventriculoperitoneal shunt insertion presenting with intraventricular hemorrhage.

Surgical neurology international

Verhey LH, Elder TA, Adel JG.
PMID: 31583176
Surg Neurol Int. 2019 Sep 13;10:179. doi: 10.25259/SNI_36_2019. eCollection 2019.

BACKGROUND: Cerebral pseudoaneurysm formation associated with ventricular catheterization is an exceedingly rare complication that results from direct catheter-induced injury to a vessel. We report a case of intracerebral pseudoaneurysm formation associated with ventricular catheterization in a patient with hydrocephalus...

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Verhey LH, Elder TA, Adel JG. Iatrogenic cortical pseudoaneurysm following ventriculoperitoneal shunt insertion presenting with intraventricular hemorrhage. Surg Neurol Int. 2019;10:179doi: 10.25259/SNI_36_2019.
Verhey, L. H., Elder, T. A., & Adel, J. G. (2019). Iatrogenic cortical pseudoaneurysm following ventriculoperitoneal shunt insertion presenting with intraventricular hemorrhage. Surgical neurology international, 10179. https://doi.org/10.25259/SNI_36_2019
Verhey, Leonard H, et al. "Iatrogenic cortical pseudoaneurysm following ventriculoperitoneal shunt insertion presenting with intraventricular hemorrhage." Surgical neurology international vol. 10 (2019): 179. doi: https://doi.org/10.25259/SNI_36_2019
Verhey LH, Elder TA, Adel JG. Iatrogenic cortical pseudoaneurysm following ventriculoperitoneal shunt insertion presenting with intraventricular hemorrhage. Surg Neurol Int. 2019 Sep 13;10:179. doi: 10.25259/SNI_36_2019. eCollection 2019. PMID: 31583176; PMCID: PMC6763671.
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A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells.

Oncoimmunology

de Bruin RCG, Veluchamy JP, Lougheed SM, Schneiders FL, Lopez-Lastra S, Lameris R, Stam AG, Sebestyen Z, Kuball J, Molthoff CFM, Hooijberg E, Roovers RC, Santo JPD, van Bergen En Henegouwen PMP, Verheul HMW, de Gruijl TD, van der Vliet HJ.
PMID: 29296532
Oncoimmunology. 2017 Oct 20;7(1):e1375641. doi: 10.1080/2162402X.2017.1375641. eCollection 2017.

Though Vγ9Vδ2-T cells constitute only a small fraction of the total T cell population in human peripheral blood, they play a vital role in tumor defense and are therefore of major interest to explore for cancer immunotherapy. Vγ9Vδ2-T cell-based...

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de Bruin RCG, Veluchamy JP, Lougheed SM, et al. A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells. Oncoimmunology. 2017;7(1):e1375641doi: 10.1080/2162402X.2017.1375641.
de Bruin, R. C. G., Veluchamy, J. P., Lougheed, S. M., Schneiders, F. L., Lopez-Lastra, S., Lameris, R., Stam, A. G., Sebestyen, Z., Kuball, J., Molthoff, C. F. M., Hooijberg, E., Roovers, R. C., Santo, J. P. D., van Bergen En Henegouwen, P. M. P., Verheul, H. M. W., de Gruijl, T. D., & van der Vliet, H. J. (2017). A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells. Oncoimmunology, 7(1), e1375641. https://doi.org/10.1080/2162402X.2017.1375641
de Bruin, Renée C G, et al. "A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells." Oncoimmunology vol. 7,1 (2017): e1375641. doi: https://doi.org/10.1080/2162402X.2017.1375641
de Bruin RCG, Veluchamy JP, Lougheed SM, Schneiders FL, Lopez-Lastra S, Lameris R, Stam AG, Sebestyen Z, Kuball J, Molthoff CFM, Hooijberg E, Roovers RC, Santo JPD, van Bergen En Henegouwen PMP, Verheul HMW, de Gruijl TD, van der Vliet HJ. A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells. Oncoimmunology. 2017 Oct 20;7(1):e1375641. doi: 10.1080/2162402X.2017.1375641. eCollection 2017. PMID: 29296532; PMCID: PMC5739573.
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Cognitive functioning in patients with low-grade glioma: effects of hemispheric tumor location and surgical procedure.

Journal of neurosurgery

Rijnen SJM, Kaya G, Gehring K, Verheul JB, Wallis OC, Sitskoorn MM, Rutten GM.
PMID: 31731264
J Neurosurg. 2019 Nov 15;1-12. doi: 10.3171/2019.8.JNS191667. Epub 2019 Nov 15.

OBJECTIVE: The authors evaluated the cognitive performance of patients with low-grade glioma (LGG) before and after surgery, and specifically investigated 1) the effects of hemispheric tumor location and 2) the type of surgery (either with or without intraoperative stimulation...

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Rijnen SJM, Kaya G, Gehring K, et al. Cognitive functioning in patients with low-grade glioma: effects of hemispheric tumor location and surgical procedure. J Neurosurg. 2019;1-12doi: 10.3171/2019.8.JNS191667.
Rijnen, S. J. M., Kaya, G., Gehring, K., Verheul, J. B., Wallis, O. C., Sitskoorn, M. M., & Rutten, G. M. (2019). Cognitive functioning in patients with low-grade glioma: effects of hemispheric tumor location and surgical procedure. Journal of neurosurgery, 1-12. https://doi.org/10.3171/2019.8.JNS191667
Rijnen, Sophie J M, et al. "Cognitive functioning in patients with low-grade glioma: effects of hemispheric tumor location and surgical procedure." Journal of neurosurgery vol. (2019): 1-12. doi: https://doi.org/10.3171/2019.8.JNS191667
Rijnen SJM, Kaya G, Gehring K, Verheul JB, Wallis OC, Sitskoorn MM, Rutten GM. Cognitive functioning in patients with low-grade glioma: effects of hemispheric tumor location and surgical procedure. J Neurosurg. 2019 Nov 15;1-12. doi: 10.3171/2019.8.JNS191667. Epub 2019 Nov 15. PMID: 31731264.
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The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review.

Cancers

Brahm CG, van Linde ME, Enting RH, Schuur M, Otten RHJ, Heymans MW, Verheul HMW, Walenkamp AME.
PMID: 32143288
Cancers (Basel). 2020 Mar 04;12(3). doi: 10.3390/cancers12030586.

The introduction of immune checkpoint inhibitors (ICI), as a novel treatment modality, has transformed the field of oncology with unprecedented successes. However, the efficacy of ICI for patients with glioblastoma or brain metastases (BMs) from any tumor type is...

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Brahm CG, van Linde ME, Enting RH, et al. The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review. Cancers (Basel). 2020;12(3)doi: 10.3390/cancers12030586.
Brahm, C. G., van Linde, M. E., Enting, R. H., Schuur, M., Otten, R. H. J., Heymans, M. W., Verheul, H. M. W., & Walenkamp, A. M. E. (2020). The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review. Cancers, 12(3), . https://doi.org/10.3390/cancers12030586
Brahm, Cyrillo G, et al. "The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review." Cancers vol. 12,3 (2020). doi: https://doi.org/10.3390/cancers12030586
Brahm CG, van Linde ME, Enting RH, Schuur M, Otten RHJ, Heymans MW, Verheul HMW, Walenkamp AME. The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review. Cancers (Basel). 2020 Mar 04;12(3). doi: 10.3390/cancers12030586. PMID: 32143288; PMCID: PMC7139638.
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Epicardial Fibrosis Explains Increased Endo-Epicardial Dissociation and Epicardial Breakthroughs in Human Atrial Fibrillation.

Frontiers in physiology

Gharaviri A, Bidar E, Potse M, Zeemering S, Verheule S, Pezzuto S, Krause R, Maessen JG, Auricchio A, Schotten U.
PMID: 32153419
Front Physiol. 2020 Feb 21;11:68. doi: 10.3389/fphys.2020.00068. eCollection 2020.

BACKGROUND: Atrial fibrillation (AF) is accompanied by progressive epicardial fibrosis, dissociation of electrical activity between the epicardial layer and the endocardial bundle network, and transmural conduction (breakthroughs). However, causal relationships between these phenomena have not been demonstrated yet. Our...

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Gharaviri A, Bidar E, Potse M, et al. Epicardial Fibrosis Explains Increased Endo-Epicardial Dissociation and Epicardial Breakthroughs in Human Atrial Fibrillation. Front Physiol. 2020;11:68doi: 10.3389/fphys.2020.00068.
Gharaviri, A., Bidar, E., Potse, M., Zeemering, S., Verheule, S., Pezzuto, S., Krause, R., Maessen, J. G., Auricchio, A., & Schotten, U. (2020). Epicardial Fibrosis Explains Increased Endo-Epicardial Dissociation and Epicardial Breakthroughs in Human Atrial Fibrillation. Frontiers in physiology, 1168. https://doi.org/10.3389/fphys.2020.00068
Gharaviri, Ali, et al. "Epicardial Fibrosis Explains Increased Endo-Epicardial Dissociation and Epicardial Breakthroughs in Human Atrial Fibrillation." Frontiers in physiology vol. 11 (2020): 68. doi: https://doi.org/10.3389/fphys.2020.00068
Gharaviri A, Bidar E, Potse M, Zeemering S, Verheule S, Pezzuto S, Krause R, Maessen JG, Auricchio A, Schotten U. Epicardial Fibrosis Explains Increased Endo-Epicardial Dissociation and Epicardial Breakthroughs in Human Atrial Fibrillation. Front Physiol. 2020 Feb 21;11:68. doi: 10.3389/fphys.2020.00068. eCollection 2020. PMID: 32153419; PMCID: PMC7047215.
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