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Showing 1 to 12 of 35 entries
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Automated enzyme-inhibition assay for clavulanic acid in biological samples.

Journal of pharmaceutical and biomedical analysis

Legg B, Clarke JG, Davies BE, Wadds GA.
PMID: 16867676
J Pharm Biomed Anal. 1985;3(4):381-4. doi: 10.1016/0731-7085(85)80048-0.

No abstract available.

Two Cases of Splenomegaly.

Canadian Medical Association journal

Addy GA.
PMID: 20316703
Can Med Assoc J. 1928 Feb;18(2):165-7.

No abstract available.

THE PRESIDENTIAL ADDRESS.

Canadian Medical Association journal

Addy GA.
PMID: 20319285
Can Med Assoc J. 1933 Nov;29(5):461-4.

No abstract available.

One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs.

Biochimica et biophysica acta

Lock A, Forfar R, Weston C, Bowsher L, Upton GJ, Reynolds CA, Ladds G, Dixon AM.
PMID: 25157670
Biochim Biophys Acta. 2014 Dec;1838(12):3036-51. doi: 10.1016/j.bbamem.2014.08.019. Epub 2014 Aug 23.

G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors in mammals and facilitate a range of physiological responses triggered by a variety of ligands. GPCRs were thought to function as monomers, however it is now accepted that...

Computer-aided design of multi-target ligands at A.

Journal of cheminformatics

Kalash L, Val C, Azuaje J, Loza MI, Svensson F, Zoufir A, Mervin L, Ladds G, Brea J, Glen R, Sotelo E, Bender A.
PMID: 29290010
J Cheminform. 2017 Dec 30;9(1):67. doi: 10.1186/s13321-017-0249-4.

Compounds designed to display polypharmacology may have utility in treating complex diseases, where activity at multiple targets is required to produce a clinical effect. In particular, suitable compounds may be useful in treating neurodegenerative diseases by promoting neuronal survival...

A survey of moral distress in certified registered nurse anesthetists: A theoretical perspective for change in ethics education for advance practice nurses.

International journal of nursing sciences

Wands BA.
PMID: 31406813
Int J Nurs Sci. 2018 Mar 29;5(2):121-125. doi: 10.1016/j.ijnss.2018.03.006. eCollection 2018 Apr 10.

OBJECTIVE: The aim of this study was to examine the relationship between moral distress that may affect patient safety, and the clinical practice model, assessing ethical decision-making skills of certified registered nurse anesthetists (CRNAs).METHODS: A survey using the Ethical...

Creating functional groups of marine fish from categorical traits.

PeerJ

Ladds MA, Sibanda N, Arnold R, Dunn MR.
PMID: 30370185
PeerJ. 2018 Oct 23;6:e5795. doi: 10.7717/peerj.5795. eCollection 2018.

BACKGROUND: Functional groups serve two important functions in ecology: they allow for simplification of ecosystem models and can aid in understanding diversity. Despite their important applications, there has not been a universally accepted method of how to define them....

Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor.

ACS pharmacology & translational science

Deganutti G, Barkan K, Preti B, Leuenberger M, Wall M, Frenguelli BG, Lochner M, Ladds G, Reynolds CA.
PMID: 33615181
ACS Pharmacol Transl Sci. 2021 Jan 21;4(1):314-326. doi: 10.1021/acsptsci.0c00195. eCollection 2021 Feb 12.

Despite being among the most characterized G protein-coupled receptors (GPCRs), adenosine receptors (ARs) have always been a difficult target in drug design. To date, no agonist other than the natural effector and the diagnostic regadenoson has been approved for...

Investigation of hypomagnesaemia prevalence and underlying aetiology in a hospitalised cohort of dogs with ionised hypocalcaemia.

The Veterinary record

Woods GA, Oikonomidis IL, Gow AG, Tørnqvist-Johnsen C, Boyé P, Chng Y, Mellanby RJ.
PMID: 33870511
Vet Rec. 2021 Nov;189(9):e301. doi: 10.1002/vetr.301. Epub 2021 Apr 19.

OBJECTIVES: Calcium is the most abundant mineral in the body and plays a critical role in a wide range of physiological processes. Low concentrations of ionised calcium, the most metabolically available form of calcium, have been linked to an...

Occupational therapy programming for adolescents with psychosocial dysfunctions.

Occupational therapy in health care

Wade GA.
PMID: 23952278
Occup Ther Health Care. 1985;2(3):127-38. doi: 10.1080/J003v02n03_12.

The philosophical and structural components of one inpatient adolescent psychiatry program in a university center are presented. Set up to address the needs of adolescents with severe psychosocial problems, the general design of the program is described with particular...

Ultrasonic evidence of strong vibrational anharmonicity in high-Tc superconductors and its effect on determination of their elastic properties.

Physical review. B, Condensed matter

Al-Kheffaji A, Almond DP, Cankurtaran M, Fanggao C, Ford PJ, Ladds DA, Saunders GA.
PMID: 9997951
Phys Rev B Condens Matter. 1991 Mar 01;43(7):5526-5537. doi: 10.1103/physrevb.43.5526.

No abstract available.

Correction to Insights to the Binding of a Selective Adenosine A.

Journal of chemical information and modeling

Lagarias P, Barkan K, Tzortzini E, Stampelou M, Vrontaki E, Ladds G, Kolocouris A.
PMID: 32208618
J Chem Inf Model. 2020 Apr 27;60(4):2405-2406. doi: 10.1021/acs.jcim.0c00240. Epub 2020 Mar 25.

No abstract available.

Showing 1 to 12 of 35 entries