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Nucleotides Cytidine and Uridine Associated with Vitamin B12 vs B-Complex Vitamins in the Treatment of Low Back Pain: The NUBES Study.

Journal of pain research

Mibielli MAN, Nunes CP, Goldberg H, Buchman L, Oliveira L, Mezitis SGE, Wajnzstajn F, Kaufman R, Nigri R, Cytrynbaum N, Cunha KS, Santos A, Goldberg SW, Platenik NC, Rzetelna H, Futuro DB, Da Fonseca AS, Geller M.
PMID: 33116795
J Pain Res. 2020 Oct 13;13:2531-2541. doi: 10.2147/JPR.S277024. eCollection 2020.

PURPOSE: We report the results of low back pain treatment using a combination of nucleotides, uridine (UTP), cytidine (CMP) and vitamin BPATIENTS AND METHODS: Randomized, double-blind, controlled trial, of a 60-day oral treatment: Group A (n=317) receiving nucleotides+BRESULTS: Seventy-five...

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Mibielli MAN, Nunes CP, Goldberg H, et al. Nucleotides Cytidine and Uridine Associated with Vitamin B12 vs B-Complex Vitamins in the Treatment of Low Back Pain: The NUBES Study. J Pain Res. 2020;13:2531-2541doi: 10.2147/JPR.S277024.
Mibielli, M. A. N., Nunes, C. P., Goldberg, H., Buchman, L., Oliveira, L., Mezitis, S. G. E., Wajnzstajn, F., Kaufman, R., Nigri, R., Cytrynbaum, N., Cunha, K. S., Santos, A., Goldberg, S. W., Platenik, N. C., Rzetelna, H., Futuro, D. B., Da Fonseca, A. S., & Geller, M. (2020). Nucleotides Cytidine and Uridine Associated with Vitamin B12 vs B-Complex Vitamins in the Treatment of Low Back Pain: The NUBES Study. Journal of pain research, 132531-2541. https://doi.org/10.2147/JPR.S277024
Mibielli, Marco Antonio Naslausky, et al. "Nucleotides Cytidine and Uridine Associated with Vitamin B12 vs B-Complex Vitamins in the Treatment of Low Back Pain: The NUBES Study." Journal of pain research vol. 13 (2020): 2531-2541. doi: https://doi.org/10.2147/JPR.S277024
Mibielli MAN, Nunes CP, Goldberg H, Buchman L, Oliveira L, Mezitis SGE, Wajnzstajn F, Kaufman R, Nigri R, Cytrynbaum N, Cunha KS, Santos A, Goldberg SW, Platenik NC, Rzetelna H, Futuro DB, Da Fonseca AS, Geller M. Nucleotides Cytidine and Uridine Associated with Vitamin B12 vs B-Complex Vitamins in the Treatment of Low Back Pain: The NUBES Study. J Pain Res. 2020 Oct 13;13:2531-2541. doi: 10.2147/JPR.S277024. eCollection 2020. PMID: 33116795; PMCID: PMC7568635.
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A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias.

Journal of pain research

Goldberg H, Mibielli MA, Nunes CP, Goldberg SW, Buchman L, Mezitis SG, Rzetelna H, Oliveira L, Geller M, Wajnsztajn F.
PMID: 28243144
J Pain Res. 2017 Feb 15;10:397-404. doi: 10.2147/JPR.S123045. eCollection 2017.

CONTEXT: This paper reports on the results of treatment of compressive neuralgia using a combination of nucleotides (uridine triphosphate trisodium [UTP] and cytidine monophosphate disodium [CMP]) and vitamin BOBJECTIVES: To assess the safety and efficacy of the combination of...

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Goldberg H, Mibielli MA, Nunes CP, et al. A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias. J Pain Res. 2017;10:397-404doi: 10.2147/JPR.S123045.
Goldberg, H., Mibielli, M. A., Nunes, C. P., Goldberg, S. W., Buchman, L., Mezitis, S. G., Rzetelna, H., Oliveira, L., Geller, M., & Wajnsztajn, F. (2017). A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias. Journal of pain research, 10397-404. https://doi.org/10.2147/JPR.S123045
Goldberg, Henrique, et al. "A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias." Journal of pain research vol. 10 (2017): 397-404. doi: https://doi.org/10.2147/JPR.S123045
Goldberg H, Mibielli MA, Nunes CP, Goldberg SW, Buchman L, Mezitis SG, Rzetelna H, Oliveira L, Geller M, Wajnsztajn F. A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias. J Pain Res. 2017 Feb 15;10:397-404. doi: 10.2147/JPR.S123045. eCollection 2017. PMID: 28243144; PMCID: PMC5317309.
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Vernal keratoconjunctivitis and keratoconus.

Current opinion in allergy and clinical immunology

Wajnsztajn D, Solomon A.
PMID: 34269743
Curr Opin Allergy Clin Immunol. 2021 Oct 01;21(5):507-514. doi: 10.1097/ACI.0000000000000765.

PURPOSE OF REVIEW: Vernal keratoconjunctivitis (VKC) is a severe allergic inflammatory disease affecting the conjunctiva in children and young adults. Keratoconus (KC) is a progressive corneal disease characterized by thinning of the corneal stroma, increased and asymmetric corneal curvature,...

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Wajnsztajn D, Solomon A. Vernal keratoconjunctivitis and keratoconus. Curr Opin Allergy Clin Immunol. 2021;21(5):507-514doi: 10.1097/ACI.0000000000000765.
Wajnsztajn, D., & Solomon, A. (2021). Vernal keratoconjunctivitis and keratoconus. Current opinion in allergy and clinical immunology, 21(5), 507-514. https://doi.org/10.1097/ACI.0000000000000765
Wajnsztajn, Denise, and Solomon, Abraham. "Vernal keratoconjunctivitis and keratoconus." Current opinion in allergy and clinical immunology vol. 21,5 (2021): 507-514. doi: https://doi.org/10.1097/ACI.0000000000000765
Wajnsztajn D, Solomon A. Vernal keratoconjunctivitis and keratoconus. Curr Opin Allergy Clin Immunol. 2021 Oct 01;21(5):507-514. doi: 10.1097/ACI.0000000000000765. PMID: 34269743.
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