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Showing 1 to 12 of 39 entries
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Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.

Oncoimmunology

Klein C, Waldhauer I, Nicolini VG, Freimoser-Grundschober A, Nayak T, Vugts DJ, Dunn C, Bolijn M, Benz J, Stihle M, Lang S, Roemmele M, Hofer T, van Puijenbroek E, Wittig D, Moser S, Ast O, Brünker P, Gorr IH, Neumann S, de Vera Mudry MC, Hinton H, Crameri F, Saro J, Evers S, Gerdes C, Bacac M, van Dongen G, Moessner E, Umaña P.
PMID: 28405498
Oncoimmunology. 2017 Jan 11;6(3):e1277306. doi: 10.1080/2162402X.2016.1277306. eCollection 2017.

We developed cergutuzumab amunaleukin (CEA-IL2v, RG7813), a novel monomeric CEA-targeted immunocytokine, that comprises a single IL-2 variant (IL2v) moiety with abolished CD25 binding, fused to the C-terminus of a high affinity, bivalent carcinoembryonic antigen (CEA)-specific antibody devoid of Fc-mediated...

A sea-floor spreading event captured by seismometers.

Science (New York, N.Y.)

Tolstoy M, Cowen JP, Baker ET, Fornari DJ, Rubin KH, Shank TM, Waldhauser F, Bohnenstiehl DR, Forsyth DW, Holmes RC, Love B, Perfit MR, Weekly RT, Soule SA, Glazer B.
PMID: 17124289
Science. 2006 Dec 22;314(5807):1920-2. doi: 10.1126/science.1133950. Epub 2006 Nov 23.

Two-thirds of Earth's surface is formed at mid-ocean ridges, yet sea-floor spreading events are poorly understood because they occur far beneath the ocean surface. At 9 degrees 50'N on the East Pacific Rise, ocean-bottom seismometers recently recorded the microearthquake...

Analysis of corrosion processes at the surface of diamond-like carbon protected zinc selenide waveguides.

Langmuir : the ACS journal of surfaces and colloids

Janotta M, Rudolph D, Kueng A, Kranz C, Voraberger HS, Waldhauser W, Mizaikoff B.
PMID: 15379485
Langmuir. 2004 Sep 28;20(20):8634-40. doi: 10.1021/la049042h.

A detailed surface analytical study on the corrosion behavior of unprotected and diamond-like carbon (DLC)-coated mid-infrared (MIR) waveguides used in remote sensing applications at strongly oxidizing conditions is presented. High-quality DLC films, with a thickness of 100 nm serving...

Viscosity and the equation of state in high energy heavy-ion reactions.

Physical review. C, Nuclear physics

Greiner W, Katscher U, Maruhn JA, Schmidt W, Stöcker H, Waldhauser B.
PMID: 9968753
Phys Rev C Nucl Phys. 1993 Jun;47(6):2782-2793. doi: 10.1103/physrevc.47.2782.

No abstract available.

Alterations of circulating lymphocyte subsets in patients with colorectal carcinoma.

Cancer immunology, immunotherapy : CII

Waidhauser J, Nerlinger P, Arndt TT, Schiele S, Sommer F, Wolf S, Löhr P, Eser S, Müller G, Claus R, Märkl B, Rank A.
PMID: 34928423
Cancer Immunol Immunother. 2021 Dec 20; doi: 10.1007/s00262-021-03127-8. Epub 2021 Dec 20.

INTRODUCTION: Cellular immune response to cancer is known to be of great importance for tumor control. Moreover, solid tumors influence circulating lymphocytes, which has been shown for several types of cancer. In our prospective study we elucidate changes in...

Dynamics of a seafloor-spreading episode at the East Pacific Rise.

Nature

Tan YJ, Tolstoy M, Waldhauser F, Wilcock WS.
PMID: 27842380
Nature. 2016 Dec 08;540(7632):261-265. doi: 10.1038/nature20116. Epub 2016 Nov 14.

Seafloor spreading is largely unobserved because 98 per cent of the global mid-ocean-ridge system is below the ocean surface. Our understanding of the dynamic processes that control seafloor spreading is thus inferred largely from geophysical observations of spreading events...

Modular biosynthesis of plant hemicellulose and its impact on yeast cells.

Biotechnology for biofuels

Robert M, Waldhauer J, Stritt F, Yang B, Pauly M, Voiniciuc C.
PMID: 34147122
Biotechnol Biofuels. 2021 Jun 19;14(1):140. doi: 10.1186/s13068-021-01985-z.

BACKGROUND: The carbohydrate polymers that encapsulate plants cells have benefited humans for centuries and have valuable biotechnological uses. In the past 5 years, exciting possibilities have emerged in the engineering of polysaccharide-based biomaterials. Despite impressive advances on bacterial cellulose-based...

Team building: conceptual, methodological, and applied considerations.

Current opinion in psychology

Beauchamp MR, McEwan D, Waldhauser KJ.
PMID: 28813332
Curr Opin Psychol. 2017 Aug;16:114-117. doi: 10.1016/j.copsyc.2017.02.031. Epub 2017 May 17.

Team building has been identified as an important method of improving the psychological climate in which teams operate, as well as overall team functioning. Within the context of sports, team building interventions have consistently been found to result in...

Intentional suppression can lead to a reduction of memory strength: behavioral and electrophysiological findings.

Frontiers in psychology

Waldhauser GT, Lindgren M, Johansson M.
PMID: 23162489
Front Psychol. 2012 Oct 16;3:401. doi: 10.3389/fpsyg.2012.00401. eCollection 2012.

Previous research has shown that the intentional suppression of unwanted memories can lead to forgetting in later memory tests. However, the mechanisms underlying this effect remain unclear. This study employed recognition memory testing and event-related potentials (ERPs) to investigate...

Direct analysis of oxidizing agents in aqueous solution with attenuated total reflectance mid-infrared spectroscopy and diamond-like carbon protected waveguides.

Analytical chemistry

Janotta M, Vogt F, Voraberger HS, Waldhauser W, Lackner JM, Stotter C, Beutl M, Mizaikoff B.
PMID: 14719887
Anal Chem. 2004 Jan 15;76(2):384-91. doi: 10.1021/ac034699d.

A novel approach for the direct detection of oxidizing agents in aqueous solution is presented using diamond-like carbon (DLC) protected waveguides in combination with attenuated total reflectance (ATR) mid-infrared spectroscopy. Pulsed laser deposition was applied to produce high-quality DLC...

Seismic identification of along-axis hydrothermal flow on the East Pacific Rise.

Nature

Tolstoy M, Waldhauser F, Bohnenstiehl DR, Weekly RT, Kim WY.
PMID: 18185585
Nature. 2008 Jan 10;451(7175):181-4. doi: 10.1038/nature06424.

Hydrothermal circulation at the axis of mid-ocean ridges affects the chemistry of the lithosphere and overlying ocean, supports chemosynthetic biological communities and is responsible for significant heat transfer from the lithosphere to the ocean. It is commonly thought that...

Epitaxy of beta -FeSi2 on Si(111).

Physical review. B, Condensed matter

Jedrecy N, Pinchaux R, Sauvage-Simkin M, Waldhauer A, Zheng Y.
PMID: 10007096
Phys Rev B Condens Matter. 1993 Sep 15;48(12):8801-8808. doi: 10.1103/physrevb.48.8801.

No abstract available.

Showing 1 to 12 of 39 entries