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The General Medical Council: yesterday, today, tomorrow.

Transactions of the Medical Society of London

Walton J.
PMID: 3870669
Trans Med Soc Lond. 1985-1986;102:91-100.

No abstract available.

Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy.

Current treatment options in allergy

Kouser L, Kappen J, Walton RP, Shamji MH.
PMID: 28413769
Curr Treat Options Allergy. 2017;4(1):43-53. doi: 10.1007/s40521-017-0117-5. Epub 2017 Mar 10.

Allergen immunotherapy (AIT) is an immune modulating treatment for allergic diseases. Although highly effective, some patients do not respond to the treatment. To date there are no surrogate biomarkers that are predictive of the clinical response to AIT. More...

No difference in pain reduction after epidural steroid injections in diabetic versus nondiabetic patients: A retrospective cohort study.

Journal of anaesthesiology, clinical pharmacology

Wong F, Namdari B, Dupler S, Kovac MF, Makarova N, Dalton JE, Turan A.
PMID: 27006548
J Anaesthesiol Clin Pharmacol. 2016 Jan-Mar;32(1):84-8. doi: 10.4103/0970-9185.173334.

BACKGROUND AND AIMS: Diabetes affects peripheral and central neurons causing paresthesia, allodynia, hyperalgesia, and spontaneous pain. However, the effect of diabetes on response to epidural steroid injection (ESI) remains unknown. We hypothesized that diabetic patients receiving ESI will have...

A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock.

Journal of the American Chemical Society

Walton DP, Dougherty DA.
PMID: 28324654
J Am Chem Soc. 2017 Apr 05;139(13):4655-4658. doi: 10.1021/jacs.7b01548. Epub 2017 Mar 24.

Visible-light triggered quinone trimethyl locks are reported as a general design for long-wavelength photoremovable protecting groups for alcohols and amines. Intramolecular photoreduction unmasks a reactive phenol that undergoes fast lactonization to release alcohols and amines. Model substrates are released...

Is there any fundamental difference between ionic, covalent, and others types of bond? A canonical perspective on the question.

Physical chemistry chemical physics : PCCP

Walton JR, Rivera-Rivera LA, Lucchese RR, Bevan JW.
PMID: 28589191
Phys Chem Chem Phys. 2017 Jun 21;19(24):15864-15869. doi: 10.1039/c7cp02407j.

The concept of chemical bonding is normally presented and simplified through two models: the covalent bond and the ionic bond. Expansion of the ideal covalent and ionic models leads chemists to the concepts of electronegativity and polarizability, and thus...

A reconnaissance analysis of groundwater quality in the Eagle Ford shale region reveals two distinct bromide/chloride populations.

The Science of the total environment

Hildenbrand ZL, Carlton DD, Meik JM, Taylor JT, Fontenot BE, Walton JL, Henderson D, Thacker JB, Korlie S, Whyte CJ, Hudak PF, Schug KA.
PMID: 27644857
Sci Total Environ. 2017 Jan 01;575:672-680. doi: 10.1016/j.scitotenv.2016.09.070. Epub 2016 Sep 16.

The extraction of oil and natural gas from unconventional shale formations has prompted a series of investigations to examine the quality of the groundwater in the overlying aquifers. Here we present a reconnaissance analysis of groundwater quality in the...

Canonical Approaches to Applications of the Virial Theorem.

The journal of physical chemistry. A

Walton JR, Rivera-Rivera LA, Lucchese RR, Bevan JW.
PMID: 26788937
J Phys Chem A. 2016 Feb 11;120(5):817-23. doi: 10.1021/acs.jpca.5b11526. Epub 2016 Feb 02.

Canonical approaches are applied for investigation of the extraordinarily accurate electronic ground state potentials of H2(+), H2, HeH(+), and LiH using the virial theorem. These approaches will be dependent on previous investigations involving the canonical nature of E(R), the...

A Modified Reverse One-Hybrid Screen Identifies Transcriptional Activation Domains in PHYTOCHROME-INTERACTING FACTOR 3.

Frontiers in plant science

Dalton JC, Bätz U, Liu J, Curie GL, Quail PH.
PMID: 27379152
Front Plant Sci. 2016 Jun 17;7:881. doi: 10.3389/fpls.2016.00881. eCollection 2016.

Transcriptional activation domains (TADs) are difficult to predict and identify, since they are not conserved and have little consensus. Here, we describe a yeast-based screening method that is able to identify individual amino acid residues involved in transcriptional activation...

Preparative semiconductor photoredox catalysis: An emerging theme in organic synthesis.

Beilstein journal of organic chemistry

Manley DW, Walton JC.
PMID: 26664577
Beilstein J Org Chem. 2015 Sep 09;11:1570-82. doi: 10.3762/bjoc.11.173. eCollection 2015.

Heterogeneous semiconductor photoredox catalysis (SCPC), particularly with TiO2, is evolving to provide radically new synthetic applications. In this review we describe how photoactivated SCPCs can either (i) interact with a precursor that donates an electron to the semiconductor thus...

Absolute Rate Constants for the Reactions of Primary Alkyl Radicals with Aromatic Amines(1).

The Journal of organic chemistry

Burton A, Ingold KU, Walton JC.
PMID: 11667229
J Org Chem. 1996 May 31;61(11):3778-3782. doi: 10.1021/jo952162x.

Hydrogen abstraction from diarylamines (4-X-C(6)H(4))(2)NH [X = H, CH(3), C(8)H(17), CH(3)O, and Br] by the 2-methyl-2-phenylpropyl radical in n-dodecane solution was investigated by thermolysis of 3-methyl-3-phenylbutanoyl peroxide in the presence of various concentrations of the amines. The reaction is...

The 2nd:4th digit ratio, sexual dimorphism, population differences, and reproductive success. evidence for sexually antagonistic genes?.

Evolution and human behavior : official journal of the Human Behavior and Evolution Society

Manning JT, Barley L, Walton J, Lewis-Jones DI, Trivers RL, Singh D, Thornhill R, Rohde P, Bereczkei T, Henzi P, Soler M, Szwed A.
PMID: 10828555
Evol Hum Behav. 2000 May 01;21(3):163-183. doi: 10.1016/s1090-5138(00)00029-5.

The ratio between the length of the 2nd and 4th digit (2D:4D) is sexually dimorphic, with mean male 2D:4D lower than mean female 2D:4D. It recently was suggested that 2D:4D is negatively correlated with prenatal testosterone and positively correlated...

Silylated cyclohexadienes as new radical chain reducing reagents: preparative and mechanistic aspects.

Journal of the American Chemical Society

Studer A, Amrein S, Schleth F, Schulte T, Walton JC.
PMID: 12733911
J Am Chem Soc. 2003 May 14;125(19):5726-33. doi: 10.1021/ja0341743.

Various silylated 1,4-cyclohexadienes are presented as superior tin hydride substitutes for the conduction of various radical chain reductions. Debrominations, deiodinations, and deselenations can be performed using these environmentally benign reagents. Furthermore, Barton-McCombie-type deoxygenations using silylated cyclohexadienes are described. Radical...

Showing 1 to 12 of 405 entries