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Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy.

Current treatment options in allergy

Kouser L, Kappen J, Walton RP, Shamji MH.
PMID: 28413769
Curr Treat Options Allergy. 2017;4(1):43-53. doi: 10.1007/s40521-017-0117-5. Epub 2017 Mar 10.

Allergen immunotherapy (AIT) is an immune modulating treatment for allergic diseases. Although highly effective, some patients do not respond to the treatment. To date there are no surrogate biomarkers that are predictive of the clinical response to AIT. More...

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Kouser L, Kappen J, Walton RP, et al. Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy. Curr Treat Options Allergy. 2017;4(1):43-53doi: 10.1007/s40521-017-0117-5.
Kouser, L., Kappen, J., Walton, R. P., & Shamji, M. H. (2017). Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy. Current treatment options in allergy, 4(1), 43-53. https://doi.org/10.1007/s40521-017-0117-5
Kouser, Lubna, et al. "Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy." Current treatment options in allergy vol. 4,1 (2017): 43-53. doi: https://doi.org/10.1007/s40521-017-0117-5
Kouser L, Kappen J, Walton RP, Shamji MH. Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy. Curr Treat Options Allergy. 2017;4(1):43-53. doi: 10.1007/s40521-017-0117-5. Epub 2017 Mar 10. PMID: 28413769; PMCID: PMC5375961.
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A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock.

Journal of the American Chemical Society

Walton DP, Dougherty DA.
PMID: 28324654
J Am Chem Soc. 2017 Apr 05;139(13):4655-4658. doi: 10.1021/jacs.7b01548. Epub 2017 Mar 24.

Visible-light triggered quinone trimethyl locks are reported as a general design for long-wavelength photoremovable protecting groups for alcohols and amines. Intramolecular photoreduction unmasks a reactive phenol that undergoes fast lactonization to release alcohols and amines. Model substrates are released...

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Walton DP, Dougherty DA. A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock. J Am Chem Soc. 2017;139(13):4655-4658doi: 10.1021/jacs.7b01548.
Walton, D. P., & Dougherty, D. A. (2017). A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock. Journal of the American Chemical Society, 139(13), 4655-4658. https://doi.org/10.1021/jacs.7b01548
Walton, David P, and Dougherty, Dennis A. "A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock." Journal of the American Chemical Society vol. 139,13 (2017): 4655-4658. doi: https://doi.org/10.1021/jacs.7b01548
Walton DP, Dougherty DA. A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock. J Am Chem Soc. 2017 Apr 05;139(13):4655-4658. doi: 10.1021/jacs.7b01548. Epub 2017 Mar 24. PMID: 28324654.
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Ag.

Dalton transactions (Cambridge, England : 2003)

Casañ-Pastor N, Rius J, Vallcorba O, Peral I, Oró-Solé J, Cook DS, Walton RI, García A, Muñoz-Rojas D.
PMID: 28045173
Dalton Trans. 2017 Jan 24;46(4):1093-1104. doi: 10.1039/c6dt03986c.

Ag

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Casañ-Pastor N, Rius J, Vallcorba O, et al. Ag. Dalton Trans. 2017;46(4):1093-1104doi: 10.1039/c6dt03986c.
Casañ-Pastor, N., Rius, J., Vallcorba, O., Peral, I., Oró-Solé, J., Cook, D. S., Walton, R. I., García, A., & Muñoz-Rojas, D. (2017). Ag. Dalton transactions (Cambridge, England : 2003), 46(4), 1093-1104. https://doi.org/10.1039/c6dt03986c
Casañ-Pastor, Nieves, et al. "Ag." Dalton transactions (Cambridge, England : 2003) vol. 46,4 (2017): 1093-1104. doi: https://doi.org/10.1039/c6dt03986c
Casañ-Pastor N, Rius J, Vallcorba O, Peral I, Oró-Solé J, Cook DS, Walton RI, García A, Muñoz-Rojas D. Ag. Dalton Trans. 2017 Jan 24;46(4):1093-1104. doi: 10.1039/c6dt03986c. PMID: 28045173.
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Author's response.

Journal of the American Dental Association (1939)

Walton RE.
PMID: 28550843
J Am Dent Assoc. 2017 Jun;148(6):357-358. doi: 10.1016/j.adaj.2017.04.016.

No abstract available.

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Walton RE. Author's response. J Am Dent Assoc. 2017;148(6):357-358doi: 10.1016/j.adaj.2017.04.016.
Walton, R. E. (2017). Author's response. Journal of the American Dental Association (1939), 148(6), 357-358. https://doi.org/10.1016/j.adaj.2017.04.016
Walton, Richard E. "Author's response." Journal of the American Dental Association (1939) vol. 148,6 (2017): 357-358. doi: https://doi.org/10.1016/j.adaj.2017.04.016
Walton RE. Author's response. J Am Dent Assoc. 2017 Jun;148(6):357-358. doi: 10.1016/j.adaj.2017.04.016. PMID: 28550843.
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Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue.

Physiological reports

Walton RG, Finlin BS, Mula J, Long DE, Zhu B, Fry CS, Westgate PM, Lee JD, Bennett T, Kern PA, Peterson CA.
PMID: 26038468
Physiol Rep. 2015 Jun;3(6). doi: 10.14814/phy2.12415.

Reduced vessel density in adipose tissue and skeletal muscle is associated with obesity and may result in decreased perfusion, decreased oxygen consumption, and insulin resistance. In the presence of VEGFA, Angiopoietin-2 (Angpt2) and Angiopoietin-1 (Angpt1) are central determinants of...

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Walton RG, Finlin BS, Mula J, et al. Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue. Physiol Rep. 2015;3(6)doi: 10.14814/phy2.12415.
Walton, R. G., Finlin, B. S., Mula, J., Long, D. E., Zhu, B., Fry, C. S., Westgate, P. M., Lee, J. D., Bennett, T., Kern, P. A., & Peterson, C. A. (2015). Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue. Physiological reports, 3(6), . https://doi.org/10.14814/phy2.12415
Walton, R Grace, et al. "Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue." Physiological reports vol. 3,6 (2015). doi: https://doi.org/10.14814/phy2.12415
Walton RG, Finlin BS, Mula J, Long DE, Zhu B, Fry CS, Westgate PM, Lee JD, Bennett T, Kern PA, Peterson CA. Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue. Physiol Rep. 2015 Jun;3(6). doi: 10.14814/phy2.12415. PMID: 26038468; PMCID: PMC4510621.
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Exchange of Coordinated Solvent During Crystallization of a Metal-Organic Framework Observed by In Situ High-Energy X-ray Diffraction.

Angewandte Chemie (International ed. in English)

Wu Y, Breeze MI, Clarkson GJ, Millange F, O'Hare D, Walton RI.
PMID: 26959076
Angew Chem Int Ed Engl. 2016 Apr 11;55(16):4992-6. doi: 10.1002/anie.201600896. Epub 2016 Mar 09.

Using time-resolved monochromatic high energy X-ray diffraction, we present an in situ study of the solvothermal crystallisation of a new MOF [Yb2(BDC)3(DMF)2]⋅H2O (BDC=benzene-1,4-dicarboxylate and DMF=N,N-dimethylformamide) under solvothermal conditions, from mixed water/DMF solvent. Analysis of high resolution powder patterns obtained...

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Wu Y, Breeze MI, Clarkson GJ, et al. Exchange of Coordinated Solvent During Crystallization of a Metal-Organic Framework Observed by In Situ High-Energy X-ray Diffraction. Angew Chem Int Ed Engl. 2016;55(16):4992-6doi: 10.1002/anie.201600896.
Wu, Y., Breeze, M. I., Clarkson, G. J., Millange, F., O'Hare, D., & Walton, R. I. (2016). Exchange of Coordinated Solvent During Crystallization of a Metal-Organic Framework Observed by In Situ High-Energy X-ray Diffraction. Angewandte Chemie (International ed. in English), 55(16), 4992-6. https://doi.org/10.1002/anie.201600896
Wu, Yue, et al. "Exchange of Coordinated Solvent During Crystallization of a Metal-Organic Framework Observed by In Situ High-Energy X-ray Diffraction." Angewandte Chemie (International ed. in English) vol. 55,16 (2016): 4992-6. doi: https://doi.org/10.1002/anie.201600896
Wu Y, Breeze MI, Clarkson GJ, Millange F, O'Hare D, Walton RI. Exchange of Coordinated Solvent During Crystallization of a Metal-Organic Framework Observed by In Situ High-Energy X-ray Diffraction. Angew Chem Int Ed Engl. 2016 Apr 11;55(16):4992-6. doi: 10.1002/anie.201600896. Epub 2016 Mar 09. PMID: 26959076; PMCID: PMC6680260.
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In Situ Observation of Successive Crystallizations and Metastable Intermediates in the Formation of Metal-Organic Frameworks.

Angewandte Chemie (International ed. in English)

Yeung HH, Wu Y, Henke S, Cheetham AK, O'Hare D, Walton RI.
PMID: 26836335
Angew Chem Int Ed Engl. 2016 Feb 05;55(6):2012-6. doi: 10.1002/anie.201508763. Epub 2016 Jan 06.

Understanding the driving forces controlling crystallization is essential for the efficient synthesis and design of new materials, particularly metal-organic frameworks (MOFs), where mild solvothermal synthesis often allows access to various phases from the same reagents. Using high-energy in situ...

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Yeung HH, Wu Y, Henke S, et al. In Situ Observation of Successive Crystallizations and Metastable Intermediates in the Formation of Metal-Organic Frameworks. Angew Chem Int Ed Engl. 2016;55(6):2012-6doi: 10.1002/anie.201508763.
Yeung, H. H., Wu, Y., Henke, S., Cheetham, A. K., O'Hare, D., & Walton, R. I. (2016). In Situ Observation of Successive Crystallizations and Metastable Intermediates in the Formation of Metal-Organic Frameworks. Angewandte Chemie (International ed. in English), 55(6), 2012-6. https://doi.org/10.1002/anie.201508763
Yeung, Hamish H-M, et al. "In Situ Observation of Successive Crystallizations and Metastable Intermediates in the Formation of Metal-Organic Frameworks." Angewandte Chemie (International ed. in English) vol. 55,6 (2016): 2012-6. doi: https://doi.org/10.1002/anie.201508763
Yeung HH, Wu Y, Henke S, Cheetham AK, O'Hare D, Walton RI. In Situ Observation of Successive Crystallizations and Metastable Intermediates in the Formation of Metal-Organic Frameworks. Angew Chem Int Ed Engl. 2016 Feb 05;55(6):2012-6. doi: 10.1002/anie.201508763. Epub 2016 Jan 06. PMID: 26836335.
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Reactions of the Dirhenium(II) Complexes Re(2)X(4)(dppm)(2) (X = Cl, Br; dppm = Ph(2)PCH(2)PPh(2)) with Isocyanides. 10.(1) Synthesis and Characterization of the Complex [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(2)(CNXyl)]O(3)SCF(3) and Several Isomeric Forms of [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(CNXyl)(2)]Y (Y = PF(6), O(3)SCF(3)).

Inorganic chemistry

Wu W, Fanwick PE, Walton RA.
PMID: 11666734
Inorg Chem. 1996 Sep 11;35(19):5484-5491. doi: 10.1021/ic960270b.

The reactions of the unsymmetrical, coordinatively unsaturated dirhenium(II) complexes [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(CNXyl)]Y (XylNC = 2,6-dimethylphenyl isocyanide; Y = O(3)SCF(3) (3a), PF(6) (3b)) with XylNC afford at least three isomeric forms of the complex cation [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(CNXyl)(2)](+). Two forms have very similar bis(&mgr;-halo)-bridged...

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Wu W, Fanwick PE, Walton RA. Reactions of the Dirhenium(II) Complexes Re(2)X(4)(dppm)(2) (X = Cl, Br; dppm = Ph(2)PCH(2)PPh(2)) with Isocyanides. 10.(1) Synthesis and Characterization of the Complex [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(2)(CNXyl)]O(3)SCF(3) and Several Isomeric Forms of [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(CNXyl)(2)]Y (Y = PF(6), O(3)SCF(3)). Inorg Chem. 1996;35(19):5484-5491doi: 10.1021/ic960270b.
Wu, W., Fanwick, P. E., & Walton, R. A. (1996). Reactions of the Dirhenium(II) Complexes Re(2)X(4)(dppm)(2) (X = Cl, Br; dppm = Ph(2)PCH(2)PPh(2)) with Isocyanides. 10.(1) Synthesis and Characterization of the Complex [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(2)(CNXyl)]O(3)SCF(3) and Several Isomeric Forms of [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(CNXyl)(2)]Y (Y = PF(6), O(3)SCF(3)). Inorganic chemistry, 35(19), 5484-5491. https://doi.org/10.1021/ic960270b
Wu, Wengan, et al. "Reactions of the Dirhenium(II) Complexes Re(2)X(4)(dppm)(2) (X = Cl, Br; dppm = Ph(2)PCH(2)PPh(2)) with Isocyanides. 10.(1) Synthesis and Characterization of the Complex [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(2)(CNXyl)]O(3)SCF(3) and Several Isomeric Forms of [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(CNXyl)(2)]Y (Y = PF(6), O(3)SCF(3))." Inorganic chemistry vol. 35,19 (1996): 5484-5491. doi: https://doi.org/10.1021/ic960270b
Wu W, Fanwick PE, Walton RA. Reactions of the Dirhenium(II) Complexes Re(2)X(4)(dppm)(2) (X = Cl, Br; dppm = Ph(2)PCH(2)PPh(2)) with Isocyanides. 10.(1) Synthesis and Characterization of the Complex [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(2)(CNXyl)]O(3)SCF(3) and Several Isomeric Forms of [Re(2)Br(3)(&mgr;-dppm)(2)(CO)(CNXyl)(2)]Y (Y = PF(6), O(3)SCF(3)). Inorg Chem. 1996 Sep 11;35(19):5484-5491. doi: 10.1021/ic960270b. PMID: 11666734.
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An intramolecular disproportionation reaction leading to the formation of the quadruply bonded complex Cl(4)ReReCl(2)(dppf) (dppf = 1,1'-bis(diphenylphosphino)ferrocene). An example of the missing 1,3-Re(2)Cl(6)(PR(3))(2) isomer.

Inorganic chemistry

Reddy ND, Fanwick PE, Walton RA.
PMID: 11312726
Inorg Chem. 2001 Apr 09;40(8):1732-3. doi: 10.1021/ic0011819.

No abstract available.

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Reddy ND, Fanwick PE, Walton RA. An intramolecular disproportionation reaction leading to the formation of the quadruply bonded complex Cl(4)ReReCl(2)(dppf) (dppf = 1,1'-bis(diphenylphosphino)ferrocene). An example of the missing 1,3-Re(2)Cl(6)(PR(3))(2) isomer. Inorg Chem. 2001;40(8):1732-3doi: 10.1021/ic0011819.
Reddy, N. D., Fanwick, P. E., & Walton, R. A. (2001). An intramolecular disproportionation reaction leading to the formation of the quadruply bonded complex Cl(4)ReReCl(2)(dppf) (dppf = 1,1'-bis(diphenylphosphino)ferrocene). An example of the missing 1,3-Re(2)Cl(6)(PR(3))(2) isomer. Inorganic chemistry, 40(8), 1732-3. https://doi.org/10.1021/ic0011819
Reddy, N D, et al. "An intramolecular disproportionation reaction leading to the formation of the quadruply bonded complex Cl(4)ReReCl(2)(dppf) (dppf = 1,1'-bis(diphenylphosphino)ferrocene). An example of the missing 1,3-Re(2)Cl(6)(PR(3))(2) isomer." Inorganic chemistry vol. 40,8 (2001): 1732-3. doi: https://doi.org/10.1021/ic0011819
Reddy ND, Fanwick PE, Walton RA. An intramolecular disproportionation reaction leading to the formation of the quadruply bonded complex Cl(4)ReReCl(2)(dppf) (dppf = 1,1'-bis(diphenylphosphino)ferrocene). An example of the missing 1,3-Re(2)Cl(6)(PR(3))(2) isomer. Inorg Chem. 2001 Apr 09;40(8):1732-3. doi: 10.1021/ic0011819. PMID: 11312726.
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Synthesis and physical properties of biquinoxalinyl bridged bis-porphyrins: models for aspects of photosynthetic reaction centres.

Organic & biomolecular chemistry

Crossley MJ, Sintic PJ, Walton R, Reimers JR.
PMID: 12948205
Org Biomol Chem. 2003 Aug 07;1(15):2777-87. doi: 10.1039/b304161a.

The synthesis of biquinoxalinyl-bridged bis-porphyrin 4 and metallated derivatives 5-11 was achieved in high yields. UV-visible spectroscopy and electrochemical experiments indicated weak orbital coupling of the two quinoxalinyl units but minimal orbital coupling between the two porphyrins. The weak...

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Crossley MJ, Sintic PJ, Walton R, et al. Synthesis and physical properties of biquinoxalinyl bridged bis-porphyrins: models for aspects of photosynthetic reaction centres. Org Biomol Chem. 2003;1(15):2777-87doi: 10.1039/b304161a.
Crossley, M. J., Sintic, P. J., Walton, R., & Reimers, J. R. (2003). Synthesis and physical properties of biquinoxalinyl bridged bis-porphyrins: models for aspects of photosynthetic reaction centres. Organic & biomolecular chemistry, 1(15), 2777-87. https://doi.org/10.1039/b304161a
Crossley, Maxwell J, et al. "Synthesis and physical properties of biquinoxalinyl bridged bis-porphyrins: models for aspects of photosynthetic reaction centres." Organic & biomolecular chemistry vol. 1,15 (2003): 2777-87. doi: https://doi.org/10.1039/b304161a
Crossley MJ, Sintic PJ, Walton R, Reimers JR. Synthesis and physical properties of biquinoxalinyl bridged bis-porphyrins: models for aspects of photosynthetic reaction centres. Org Biomol Chem. 2003 Aug 07;1(15):2777-87. doi: 10.1039/b304161a. PMID: 12948205.
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Connectivity effects in isomeric naphthalenedinitrenes.

Organic letters

Serwinski PR, Walton R, Sanborn JA, Lahti PM, Enyo T, Miura D, Tomioka H, Nicolaides A.
PMID: 11428013
Org Lett. 2001 Feb 08;3(3):357-60. doi: 10.1021/ol0068288.

[figure: see text] UV-vis, FTIR, and ESR spectroscopic studies were carried out on samples of 1,4- and 1,5-naphthalenediazide that were photolyzed at cryogenic temperatures in argon and frozen solvent matrices. Mononitrenes and diiminediyl systems are produced. Spectral and computational...

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Serwinski PR, Walton R, Sanborn JA, et al. Connectivity effects in isomeric naphthalenedinitrenes. Org Lett. 2001;3(3):357-60doi: 10.1021/ol0068288.
Serwinski, P. R., Walton, R., Sanborn, J. A., Lahti, P. M., Enyo, T., Miura, D., Tomioka, H., & Nicolaides, A. (2001). Connectivity effects in isomeric naphthalenedinitrenes. Organic letters, 3(3), 357-60. https://doi.org/10.1021/ol0068288
Serwinski, P R, et al. "Connectivity effects in isomeric naphthalenedinitrenes." Organic letters vol. 3,3 (2001): 357-60. doi: https://doi.org/10.1021/ol0068288
Serwinski PR, Walton R, Sanborn JA, Lahti PM, Enyo T, Miura D, Tomioka H, Nicolaides A. Connectivity effects in isomeric naphthalenedinitrenes. Org Lett. 2001 Feb 08;3(3):357-60. doi: 10.1021/ol0068288. PMID: 11428013.
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Volume integration of fractal distribution networks.

Physical review. E, Statistical, nonlinear, and soft matter physics

Gutierrez WR.
PMID: 12443234
Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Oct;66(4):041906. doi: 10.1103/PhysRevE.66.041906. Epub 2002 Oct 21.

An approach based on integral calculus methods is developed in order to determine the volume of a distribution network with fractal characteristics. This approach introduces alternative useful techniques and concepts to the study of the self-similarity of fractal distribution...

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Gutierrez WR. Volume integration of fractal distribution networks. Phys Rev E Stat Nonlin Soft Matter Phys. 2002;66(4):041906doi: 10.1103/PhysRevE.66.041906.
Gutierrez, W. R. (2002). Volume integration of fractal distribution networks. Physical review. E, Statistical, nonlinear, and soft matter physics, 66(4), 041906. https://doi.org/10.1103/PhysRevE.66.041906
Gutierrez, Walton R. "Volume integration of fractal distribution networks." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 66,4 (2002): 041906. doi: https://doi.org/10.1103/PhysRevE.66.041906
Gutierrez WR. Volume integration of fractal distribution networks. Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Oct;66(4):041906. doi: 10.1103/PhysRevE.66.041906. Epub 2002 Oct 21. PMID: 12443234.
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