Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 145 entries
Sorted by: Best Match Show Resources per page
Upper esophageal sphincter mechanical states analysis: a novel methodology to describe UES relaxation and opening.

Frontiers in systems neuroscience

Omari TI, Wiklendt L, Dinning P, Costa M, Rommel N, Cock C.
PMID: 25610376
Front Syst Neurosci. 2015 Jan 07;8:241. doi: 10.3389/fnsys.2014.00241. eCollection 2014.

The swallowing muscles that influence upper esophageal sphincter (UES) opening are centrally controlled and modulated by sensory information. Activation of neural inputs to these muscles, the intrinsic cricopharyngeus muscle and extrinsic suprahyoid muscles, results in their contraction or relaxation,...

Minimally invasive thymectomy: the Mayo Clinic experience.

Annals of cardiothoracic surgery

Rowse PG, Roden AC, Corl FM, Allen MS, Cassivi SD, Nichols FC, Shen KR, Wigle DA, Blackmon SH.
PMID: 26693147
Ann Cardiothorac Surg. 2015 Nov;4(6):519-26. doi: 10.3978/j.issn.2225-319X.2015.07.03.

BACKGROUND: The prevalence of minimally invasive thymectomy (MIT) is increasing and may have significant benefit to patients in terms of morbidity and post-operative recovery. Our aim was to review the Mayo Clinic experience of MIT.METHODS: We reviewed data from...

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.

ACS medicinal chemistry letters

Mitchell LH, Drew AE, Ribich SA, Rioux N, Swinger KK, Jacques SL, Lingaraj T, Boriack-Sjodin PA, Waters NJ, Wigle TJ, Moradei O, Jin L, Riera T, Porter-Scott M, Moyer MP, Smith JJ, Chesworth R, Copeland RA.
PMID: 26101569
ACS Med Chem Lett. 2015 Apr 06;6(6):655-9. doi: 10.1021/acsmedchemlett.5b00071. eCollection 2015 Jun 11.

A novel aryl pyrazole series of arginine methyltransferase inhibitors has been identified. Synthesis of analogues within this series yielded the first potent, selective, small molecule PRMT6 inhibitor tool compound, EPZ020411. PRMT6 overexpression has been reported in several cancer types...

A new route to chelating bis(aryloxide) ligands and their applications to tantalum and titanium organometallic compounds.

Inorganic chemistry

Anthis JW, Filippov I, Wigley DE.
PMID: 14731035
Inorg Chem. 2004 Jan 26;43(2):716-24. doi: 10.1021/ic030300s.

A new route to sterically tuned, chelating bis(aryloxide) ligands is described and demonstrated by the synthesis of 2,2'-ethylenebis(6-isopropylphenol) (1, H(2)BIPP) and transition metal complexes of its dianion. The utility of these ligands in titanium and tantalum organometallic chemistry is...

Analysis of order statistic filters applied to ultrasonic flaw detection using split-spectrum processing.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Saniie J, Nagle DT, Donohue KD.
PMID: 18267567
IEEE Trans Ultrason Ferroelectr Freq Control. 1991;38(2):133-40. doi: 10.1109/58.68470.

Split-spectrum processing of broadband ultrasonic signals coupled with order statistic filtering has proven to be effective in improving the flaw-to-clutter ratio of backscattered signals. It is shown that an optimal rank can be obtained with a prior knowledge of...

Analysis of order-statistic CFAR threshold estimators for improved ultrasonic flaw detection.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Saniie J, Nagle DT.
PMID: 18267673
IEEE Trans Ultrason Ferroelectr Freq Control. 1992;39(5):618-30. doi: 10.1109/58.156180.

In the pulse-echo method using broadband transducers, flaw detection can be improved by using optimal bandpass filtering to resolve flaw echoes surrounded by grain scatterers. Optimal bandpass filtering is achieved by examining spectral information of the flaw and grain...

Real-time fluorescence imaging of isotachophoretic preconcentration for capillary electrophoresis.

Analytical chemistry

Johansson J, Witte DT, Larsson M, Nilsson S.
PMID: 21619349
Anal Chem. 1996 Sep 01;68(17):2766-70. doi: 10.1021/ac951071x.

Real-time studies of the dynamic processes that take place during isotachophoresis (ITP) were performed. The experimental arrangement utilized was a real-time fluorescence imaging system based on a dye laser at 488 nm, pumped by a XeCl excimer laser. Fluorescence...

Utilization, spending, and price trends for short- and long-acting Beta-agonists and inhaled corticosteroids in the medicaid program, 1991-2010.

American health & drug benefits

Chiu SF, Kelton CM, Guo JJ, Wigle PR, Lin AC, Szeinbach SL.
PMID: 25126346
Am Health Drug Benefits. 2011 May;4(3):140-9.

BACKGROUND: Asthma is a chronic respiratory disease that afflicts millions of people and accounts for substantial utilization of healthcare resources in most industrialized countries, including in the United States. However, the exact cost and utilization of anti-asthma medications in...

Epigenetics: Tools and Technologies.

Drug discovery today. Technologies

Janzen WP, Wigle TJ, Jin J, Frye SV.
PMID: 21243036
Drug Discov Today Technol. 2010;7(1):e59-e65. doi: 10.1016/j.ddtec.2010.07.004.

Epigenetics refers to heritable changes that control how the genome is accessed in different cell-types and during development and differentiation. Even though each cell contains essentially the same genetic code, epigenetic mechanisms permit specialization of function between cells. The...

Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA.

Cell & bioscience

Deng B, Molina J, Aubry MC, Sun Z, Wang L, Eckloff BW, Vasmatzis G, You M, Wieben ED, Jen J, Wigle DA, Yang P.
PMID: 25105010
Cell Biosci. 2014 Jul 09;4:35. doi: 10.1186/2045-3701-4-35. eCollection 2014.

BACKGROUND: miRNAs play key regulatory roles in cellular pathological processes. We aimed to identify clinically meaningful biomarkers in pulmonary carcinoid tumors (PCTs), a member of neuroendocrine neoplasms, via profiling miRNAs and mRNAs.RESULTS: From the total of 1145 miRNAs, we...

Nutritional evaluation by rat feeding of preparations from guar seed (Cyamopsis tetragonoloba) including supplementation with lysine and methionine.

Journal of agricultural and food chemistry

Kawatra BL, Garcha JS, Wagle DS.
PMID: 21428369
J Agric Food Chem. 1969 Sep;17(5):1142-5. doi: 10.1021/jf60165a005.

No abstract available.

Intractable computations without local minima.

Physical review letters

Wille LT.
PMID: 10035745
Phys Rev Lett. 1987 Jul 20;59(3):372. doi: 10.1103/PhysRevLett.59.372.

No abstract available.

Showing 1 to 12 of 145 entries