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Action in international medicine.

International journal of dermatology

Wolstenholme G.
PMID: 2722334
Int J Dermatol. 1989 May;28(4):226-7. doi: 10.1111/j.1365-4362.1989.tb04807.x.

No abstract available.

Anthelmintics - from discovery to resistance.

International journal for parasitology. Drugs and drug resistance

Wolstenholme AJ, Martin RJ.
PMID: 25516831
Int J Parasitol Drugs Drug Resist. 2014 Nov 22;4(3):218-9. doi: 10.1016/j.ijpddr.2014.10.001. eCollection 2014 Dec.

The scientific meeting entitled 'Anthelmintics: From Discovery to Resistance' was held in San Francisco in February 2014. The themes of the meeting were drug discovery, modes of action and resistance. Both human and veterinary parasites were covered in the...

Homopolar dihydrogen bonding in main group hydrides: discovery, consequences, and applications.

Dalton transactions (Cambridge, England : 2003)

Wolstenholme DJ, Dobson JL, McGrady GS.
PMID: 25915435
Dalton Trans. 2015 Jun 07;44(21):9718-31. doi: 10.1039/c5dt00221d.

This perspective describes the recent discovery and investigation of homopolar dihydrogen bonding, and focuses on the identification and characterisation of hydride-hydride interactions in compounds of the main group elements. A highlight of this programme has been an appreciation of...

Raman spectroscopic analysis of the enigmatic Comper pigments.

Analytical and bioanalytical chemistry

Edwards HG, Wolstenholme R, Wilkinson DS, Brooke C, Pepper M.
PMID: 17242886
Anal Bioanal Chem. 2007 Mar;387(6):2255-62. doi: 10.1007/s00216-006-1113-y. Epub 2007 Jan 23.

An early church decoration project carried out by Sir Ninian Comper in 1896-98, involving the rood screen and canopy in St. Mary's, Egmanton, is currently undergoing restoration. Despite the rather prolific works of this famous ecclesiastical architect, there is...

Comparative study of weak interactions in molecular crystals: H-H bonds vs hydrogen bonds.

The journal of physical chemistry. A

Wolstenholme DJ, Cameron TS.
PMID: 16836461
J Phys Chem A. 2006 Jul 20;110(28):8970-8. doi: 10.1021/jp061205i.

The crystal structures of tetraphenylphosphonium squarate, bianthrone, and bis(benzophenone)azine are shown to contain a variety of C-H(delta+)...(delta+)H-C interactions, as well as a variety of C-H...O and C-H...C(pi) interactions. Each of these molecules possesses interactions that can possibly be characterized...

Homopolar dihydrogen bonding in alkali metal amidoboranes: crystal engineering of low-dimensional molecular materials.

Journal of the American Chemical Society

Wolstenholme DJ, Flogeras J, Che FN, Decken A, McGrady GS.
PMID: 23363072
J Am Chem Soc. 2013 Feb 20;135(7):2439-42. doi: 10.1021/ja311778k. Epub 2013 Feb 08.

Hydrogen bonding is a predominant interaction in supramolecular chemistry. The absence of a conventional hydrogen bond donor in LiNMe(2)BH(3) and KNMe(2)BH(3) results in the formation of elaborate M···H-B polymeric arrays supported by heteropolar and homopolar H···H bonding, in a...

Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice.

Frontiers in genetics

O'Brien MA, Weston RM, Sheth NU, Bradley S, Bigbee J, Pandey A, Williams RW, Wolstenholme JT, Miles MF.
PMID: 30319688
Front Genet. 2018 Sep 24;9:402. doi: 10.3389/fgene.2018.00402. eCollection 2018.

Alcoholism is a complex behavioral disorder characterized by loss of control in limiting intake, and progressive compulsion to seek and consume ethanol. Prior studies have suggested that the characteristic behaviors associated with escalation of drug use are caused, at...

Improving self-efficacy in spinal cord injury patients through "design thinking" rehabilitation workshops.

BMJ quality improvement reports

Wolstenholme D, Downes T, Leaver J, Partridge R, Langley J.
PMID: 27493735
BMJ Qual Improv Rep. 2014 Oct 16;3(1). doi: 10.1136/bmjquality.u205728.w2340. eCollection 2014.

Advances in surgical and medical management have significantly reduced the length of time that patients with spinal cord injury (SCI) have to stay in hospital, but has left patients with potentially less time to psychologically adjust. Following a pilot...

The Effect of Moderate- and High-Fat Meals on the Bioavailability of Dolutegravir/Rilpivirine Fixed-Dose Combination Tablet.

Clinical pharmacology : advances and applications

Mehta R, Piscitelli J, Wolstenholme A, Fu C, Crauwels H, Wynne B, Adkison K.
PMID: 32607002
Clin Pharmacol. 2020 Jun 08;12:49-52. doi: 10.2147/CPAA.S250751. eCollection 2020.

Dolutegravir 50 mg (DTG) and rilpivirine 25 mg (RPV) are a newly approved 2-drug regimen for the treatment of HIV in virally suppressed patients. A 2-part study evaluated the relative bioavailability and food effect of five experimental fixed-dose combination...

Tumor mutation burden testing: a survey of the International Quality Network for Pathology (IQN Path).

Virchows Archiv : an international journal of pathology

Fenizia F, Wolstenholme N, Fairley JA, Rouleau E, Cheetham MH, Horan MP, Torlakovic E, Besse B, Al Dieri R, Tiniakos DG, Deans ZC, Patton SJ, Normanno N.
PMID: 33856555
Virchows Arch. 2021 Dec;479(6):1067-1072. doi: 10.1007/s00428-021-03093-7. Epub 2021 Apr 15.

While tumour mutation burden (TMB) is emerging as a possible biomarker for immune-checkpoint inhibitors (ICI), methods for testing have not been standardised as yet. In April 2019, the International Quality Network for Pathology (IQN Path) launched a survey to...

Tumor mutation burden testing: a survey of the International Quality Network for Pathology (IQN Path).

Virchows Archiv : an international journal of pathology

Fenizia F, Wolstenholme N, Fairley JA, Rouleau E, Cheetham MH, Horan MP, Torlakovic E, Besse B, Al Dieri R, Tiniakos DG, Deans ZC, Patton SJ, Normanno N.
PMID: 33856555
Virchows Arch. 2021 Apr 15; doi: 10.1007/s00428-021-03093-7. Epub 2021 Apr 15.

While tumour mutation burden (TMB) is emerging as a possible biomarker for immune-checkpoint inhibitors (ICI), methods for testing have not been standardised as yet. In April 2019, the International Quality Network for Pathology (IQN Path) launched a survey to...

The costs of bipolar disorder in the United Kingdom.

Brain and behavior

Simon J, Pari AAA, Wolstenholme J, Berger M, Goodwin GM, Geddes JR.
PMID: 34523820
Brain Behav. 2021 Oct;11(10):e2351. doi: 10.1002/brb3.2351. Epub 2021 Sep 15.

OBJECTIVES: To estimate the individual cost and population-level economic burden of Bipolar Disorder (BD), and explore the impact of clinical and sociodemographic factors on costs in the United Kingdom.METHODS: Annual UK health care, social care and societal cost data...

Showing 1 to 12 of 65 entries