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Showing 1 to 12 of 331 entries
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(E)-1-[2-(4-Chloro-2-nitro-styr-yl)-1-phenyl-sulfonyl-1H-indol-3-yl]propan-1-one.

Acta crystallographica. Section E, Structure reports online

Umadevi M, Saravanan V, Yamuna R, Mohanakrishnan AK, Chakkaravarthi G.
PMID: 24860289
Acta Crystallogr Sect E Struct Rep Online. 2013 Nov 16;69:o1784. doi: 10.1107/S1600536813031073. eCollection 2013 Dec 01.

In the title compound, C25H19ClN2O5S, the phenyl ring forms dihedral angles of 79.62 (12) and 80.02 (13)° with the indole ring system and the benzene ring, respectively. The nitro group is twisted at an angle of 22.39 (11)° with...

Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor.

Neuron

Murakoshi H, Shin ME, Parra-Bueno P, Szatmari EM, Shibata ACE, Yasuda R.
PMID: 28472663
Neuron. 2017 May 03;94(3):690. doi: 10.1016/j.neuron.2017.04.027.

No abstract available.

Intravenous immune globulin suppresses angiogenesis in mice and humans.

Signal transduction and targeted therapy

Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J.
PMID: 26925256
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28.

Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~ 60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are...

Optical Magnetoelectric Resonance in a Polar Magnet (Fe,Zn)_{2}Mo_{3}O_{8} with Axion-Type Coupling.

Physical review letters

Kurumaji T, Takahashi Y, Fujioka J, Masuda R, Shishikura H, Ishiwata S, Tokura Y.
PMID: 28949678
Phys Rev Lett. 2017 Aug 18;119(7):077206. doi: 10.1103/PhysRevLett.119.077206. Epub 2017 Aug 18.

We report the polarization rotation of terahertz light resonant with the magnetoelectric (ME) spin excitation in the multiferroic (Fe,Zn)_{2}Mo_{3}O_{8}. This resonance reflects the frequency dispersion of the diagonal ME susceptibility (axion term), with which we quantitatively reproduce the thermal...

On the road to standardization of D2 lymph node dissection in a European population of patients with gastric cancer.

World journal of gastrointestinal oncology

Yarema R, de Manzoni G, Fetsych T, Ohorchak M, Pliatsko M, Bencivenga M.
PMID: 27326318
World J Gastrointest Oncol. 2016 Jun 15;8(6):489-97. doi: 10.4251/wjgo.v8.i6.489.

The amount of lymph node dissection (LD) required during surgical treatment of gastric cancer surgery has been quite controversial. In the 1970s and 1980s, Japanese surgeons developed a doctrine of aggressive preventive gastric cancer surgery that was based on...

ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis.

Cell reports

Takagi M, Uno H, Nishi R, Sugimoto M, Hasegawa S, Piao J, Ihara N, Kanai S, Kakei S, Tamura Y, Suganami T, Kamei Y, Shimizu T, Yasuda A, Ogawa Y, Mizutani S.
PMID: 25683718
Cell Rep. 2015 Feb 17;10(6):957-967. doi: 10.1016/j.celrep.2015.01.027. Epub 2015 Feb 12.

Ataxia-telangiectasia (A-T) patients occasionally develop diabetes mellitus. However, only limited attempts have been made to gain insight into the molecular mechanism of diabetes mellitus development in A-T patients. We found that Atm

A case of type 2 diabetes mellitus with metformin-associated lactic acidosis initially presenting the appearance of a sulfonylurea-related hypoglycemic attack.

Acute medicine & surgery

Nishihama K, Maki K, Okano Y, Hashimoto R, Hotta Y, Uemura M, Yasuma T, Suzuki T, Hayashi T, Ishikawa E, Yano Y, Gabazza EC, Ito M, Takei Y.
PMID: 29123848
Acute Med Surg. 2016 Aug 03;4(1):123-126. doi: 10.1002/ams2.233. eCollection 2017 Jan.

CASE: A 64-year-old Japanese woman with diabetes mellitus was admitted for hypoglycemia. Her diabetes had been under good control with glimepiride, voglibose, exenatide, and metformin for a few years. Although overt proteinuria was observed, the serum creatinine values were...

Activated protein C modulates the proinflammatory activity of dendritic cells.

Journal of asthma and allergy

Matsumoto T, Matsushima Y, Toda M, Roeen Z, D'Alessandro-Gabazza CN, Hinneh JA, Harada E, Yasuma T, Yano Y, Urawa M, Kobayashi T, Taguchi O, Gabazza EC.
PMID: 26005353
J Asthma Allergy. 2015 May 07;8:29-37. doi: 10.2147/JAA.S75261. eCollection 2015.

BACKGROUND: Previous studies have demonstrated the beneficial activity of activated protein C in allergic diseases including bronchial asthma and rhinitis. However, the exact mechanism of action of activated protein C in allergies is unclear. In this study, we hypothesized...

Varicella-zoster virus encephalitis localized to the bilateral medial temporal lobes.

Neurology(R) neuroimmunology & neuroinflammation

Yajima R, Utsumi K, Ishihara T, Kanazawa M, Okamoto K, Kawachi I, Nishizawa M.
PMID: 25977935
Neurol Neuroimmunol Neuroinflamm. 2015 May 07;2(4):e108. doi: 10.1212/NXI.0000000000000108. eCollection 2015 Aug.

No abstract available.

Crystal structure of N-{[3-bromo-1-(phenyl-sulfon-yl)-1H-indol-2-yl]meth-yl}benzene-sulfonamide.

Acta crystallographica. Section E, Crystallographic communications

Umadevi M, Raju P, Yamuna R, Mohanakrishnan AK, Chakkaravarthi G.
PMID: 26594460
Acta Crystallogr E Crystallogr Commun. 2015 Sep 17;71:o756-7. doi: 10.1107/S2056989015016874. eCollection 2015 Oct 01.

In the title compound, C21H17BrN2O4S2, the indole ring system subtends dihedral angles of 85.96 (13) and 9.62 (16)° with the planes of the N- and C-bonded benzene rings, respectively. The dihedral angles between the benzene rings is 88.05 (17)°....

The multiplicity of post-translational modifications in pro-opiomelanocortin-derived peptides.

Frontiers in endocrinology

Yasuda A, Jones LS, Shigeri Y.
PMID: 24348461
Front Endocrinol (Lausanne). 2013 Dec 02;4:186. doi: 10.3389/fendo.2013.00186.

The precursor protein, pro-opiomelanocortin (POMC) undergoes extensive post-translational processing in a tissue-specific manner to yield various biologically active peptides involved in diverse cellular functions. The recently developed method of matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for direct tissue analysis...

Crystal structure of 2-(2,4-di-chloro-phen-yl)-4-hydroxy-9-phenyl-sulfonyl-9H-carbazole-3-carbaldehyde.

Acta crystallographica. Section E, Structure reports online

Umadevi M, Ramalingam BM, Yamuna R, Mohanakrishnan AK, Chakkaravarthi G.
PMID: 25552966
Acta Crystallogr Sect E Struct Rep Online. 2014 Nov 08;70:466-8. doi: 10.1107/S1600536814024064. eCollection 2014 Dec 01.

In the title compound, C25H15Cl2NO4S, the di-chloro-phenyl ring is twisted by 68.69 (11)° from the mean plane of the carbazole ring system [r.m.s. deviation = 0.084 (2)°]. The hy-droxy group is involved in an intra-molecular O-H⋯O hydrogen bond, which...

Showing 1 to 12 of 331 entries