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Groundwater chemical baseline values to assess the Recovery Plan in the Matanza-Riachuelo River basin, Argentina.

The Science of the total environment

Zabala ME, Martínez S, Manzano M, Vives L.
PMID: 26490531
Sci Total Environ. 2016 Jan 15;541:1516-1530. doi: 10.1016/j.scitotenv.2015.10.006. Epub 2015 Nov 11.

The two most exploited aquifers in the Matanza-Riachuelo River basin are being monitored in the framework of the Integrated Environmental Sanitation Plan that implements the Basin Authority, Autoridad de Cuenca Matanza Riachuelo. In this context, this work identifies the...

RNA-Seq analysis and whole genome DNA-binding profile of the .

Genomics data

Ayala JC, Wang H, Benitez JA, Silva AJ, Conway P.
PMID: 26097806
Genom Data. 2015 Sep 01;5:147-150. doi: 10.1016/j.gdata.2015.05.039.

The data described in this article pertain to the genome-wide transcription profiling of a

Structured covariance principal component analysis for real-time onsite feature extraction and dimensionality reduction in hyperspectral imaging.

Applied optics

Zabalza J, Ren J, Ren J, Liu Z, Marshall S.
PMID: 25090063
Appl Opt. 2014 Jul 10;53(20):4440-9. doi: 10.1364/AO.53.004440.

Presented in a three-dimensional structure called a hypercube, hyperspectral imaging suffers from a large volume of data and high computational cost for data analysis. To overcome such drawbacks, principal component analysis (PCA) has been widely applied for feature extraction...

Recombinant production of Streptococcus equisimilis streptokinase by Streptomyces lividans.

Microbial cell factories

Pimienta E, Ayala JC, Rodríguez C, Ramos A, Van Mellaert L, Vallín C, Anné J.
PMID: 17610745
Microb Cell Fact. 2007 Jul 05;6:20. doi: 10.1186/1475-2859-6-20.

BACKGROUND: Streptokinase (SK) is a potent plasminogen activator with widespread clinical use as a thrombolytic agent. It is naturally secreted by several strains of beta-haemolytic streptococci. The low yields obtained in SK production, lack of developed gene transfer methodology...

Abnormally high digestive enzyme activity and gene expression explain the contemporary evolution of a Diabrotica biotype able to feed on soybeans.

Ecology and evolution

Curzi MJ, Zavala JA, Spencer JL, Seufferheld MJ.
PMID: 22957201
Ecol Evol. 2012 Aug;2(8):2005-17. doi: 10.1002/ece3.331. Epub 2012 Jul 19.

Western corn rootworm (Diabrotica virgifera) (WCR) depends on the continuous availability of corn. Broad adoption of annual crop rotation between corn (Zea mays) and nonhost soybean (Glycine max) exploited WCR biology to provide excellent WCR control, but this practice...

Expression of unphosphorylated class III beta-tubulin isotype in neuroepithelial cells demonstrates neuroblast commitment and differentiation.

The European journal of neuroscience

Avila J, Fanarraga ML, Zabala JC.
PMID: 10051752
Eur J Neurosci. 1999 Feb;11(2):516-527.

Neuronal microtubules have unique stability properties achieved through developmental regulation at the expression and post-translational levels on tubulins and microtubule associated proteins. One of the most specialized tubulins specific for neurons is class-III beta-tubulin (also known as beta6-tubulin). Both...

Improving the Breadth of the Host's Immune Response to Lassa Virus.

Pathogens (Basel, Switzerland)

Zapata JC, Medina-Moreno S, Guzmán-Cardozo C, Salvato MS.
PMID: 30373278
Pathogens. 2018 Oct 28;7(4). doi: 10.3390/pathogens7040084.

In 2017, the global Coalition for Epidemic Preparedness (CEPI) declared Lassa virus disease to be one of the world's foremost biothreats. In January 2018, World Health Organization experts met to address the Lassa biothreat. It was commonly recognized that...

Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC.

Cancer discovery

Tang KH, Li S, Khodadadi-Jamayran A, Jen J, Han H, Guidry K, Chen T, Hao Y, Fedele C, Zebala JA, Maeda DY, Christensen JG, Olson P, Athanas A, Loomis CA, Tsirigos A, Wong KK, Neel BG.
PMID: 34353854
Cancer Discov. 2021 Aug 05; doi: 10.1158/2159-8290.CD-21-0369. Epub 2021 Aug 05.

SHP2 inhibitors (SHP2i) alone and in various combinations are being tested in multiple tumors with over-activation of the RAS/ERK pathway. SHP2 plays critical roles in normal cell signaling; hence, SHP2is could influence the tumor microenvironment. We found that SHP2i...

Phenotypic and environmental correlates of natal dispersal in a long-lived territorial vulture.

Scientific reports

Serrano D, Cortés-Avizanda A, Zuberogoitia I, Blanco G, Benítez JR, Ponchon C, Grande JM, Ceballos O, Morant J, Arrondo E, Zabala J, Montelío E, Ávila E, González JL, Arroyo B, Frías Ó, Kobierzycki E, Arenas R, Tella JL, Donázar JA.
PMID: 33686130
Sci Rep. 2021 Mar 08;11(1):5424. doi: 10.1038/s41598-021-84811-8.

Natal dispersal, the movement between the birth and the first breeding site, has been rarely studied in long-lived territorial birds with a long-lasting pre-breeding stage. Here we benefited from the long-term monitoring programs of six populations of Egyptian vultures...

Groundwater residence time estimates obscured by anthropogenic carbonate.

Science advances

Seltzer AM, Bekaert DV, Barry PH, Durkin KE, Mace EK, Aalseth CE, Zappala JC, Mueller P, Jurgens B, Kulongoski JT.
PMID: 33883137
Sci Adv. 2021 Apr 21;7(17). doi: 10.1126/sciadv.abf3503. Print 2021 Apr.

Groundwater is an important source of drinking and irrigation water. Dating groundwater informs its vulnerability to contamination and aids in calibrating flow models. Here, we report measurements of multiple age tracers (

Colchicine Blocks Tubulin Heterodimer Recycling by Tubulin Cofactors TBCA, TBCB, and TBCE.

Frontiers in cell and developmental biology

Nolasco S, Bellido J, Serna M, Carmona B, Soares H, Zabala JC.
PMID: 33968934
Front Cell Dev Biol. 2021 Apr 22;9:656273. doi: 10.3389/fcell.2021.656273. eCollection 2021.

Colchicine has been used to treat gout and, more recently, to effectively prevent autoinflammatory diseases and both primary and recurrent episodes of pericarditis. The anti-inflammatory action of colchicine seems to result from irreversible inhibition of tubulin polymerization and microtubule...

Heliyon

Delfino Sosa M, Zabala C, Pardo L, Fernández L, Nieves C, Más M, Barrios P, Algorta G, Mota MI, Varela A, Gutiérrez C, Gutiérrez S, Giachetto G, Pírez MC.
PMID: 32215324
Heliyon. 2020 Mar 19;6(3):e03483. doi: 10.1016/j.heliyon.2020.e03483. eCollection 2020 Mar.

BACKGROUND: Uruguay incorporated the conjugate vaccine against METHODS: Sterile site Hib isolations from hospitalized children were included. Clinical and microbiological characteristics were analyzed. Favorable conditions for the infection were considered: incomplete immunization, immunodeficiencies and associated pathologies. Two periods are...

Showing 1 to 12 of 127 entries