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Showing 1 to 12 of 52 entries
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Effects of N-acetylcysteine (NAC) supplementation in resuscitation fluids on renal microcirculatory oxygenation, inflammation, and function in a rat model of endotoxemia.

Intensive care medicine experimental

Ergin B, Guerci P, Zafrani L, Nocken F, Kandil A, Gurel-Gurevin E, Demirci-Tansel C, Ince C.
PMID: 27671340
Intensive Care Med Exp. 2016 Dec;4(1):29. doi: 10.1186/s40635-016-0106-1. Epub 2016 Sep 26.

BACKGROUND: Modulation of inflammation and oxidative stress appears to limit sepsis-induced damage in experimental models. The kidney is one of the most sensitive organs to injury during septic shock. In this study, we evaluated the effect of N-acetylcysteine (NAC)...

Calix[4, 5]tetrolarenes: A New Family of Macrocycles.

Organic letters

Zafrani Y, Cohen Y.
PMID: 28661682
Org Lett. 2017 Jul 21;19(14):3719-3722. doi: 10.1021/acs.orglett.7b01511. Epub 2017 Jun 29.

The facile and efficient one-step synthesis and the full characterization of novel π-electron rich macrocycles, calix-[n]tetrolarenes (n = 4, 5), are described. The tetramer and the much rarer sized pentamer were easily prepared by reaction of the commercially available,...

[Not Available].

Journal de chirurgie

Gouy S, Uzan C, Zafrani Y, Lhommé C, Pautier P, Duvillard P, Haie-Meder C, Morice P.
PMID: 22794074
J Chir (Paris). 2008 Dec;145(6):12S51-5. doi: 10.1016/S0021-7697(08)45010-X.

S. Gouy, C. Uzan, Y. Zafrani, C. Lhommé, P. Pautier, P. Duvillard, C. Haie-Meder, P. Morice Uterine cancer can metastasize to both the pelvic and para-aortic levels. No one questions the diagnostic and prognostic value of lymphadenectomy, but its...

Pillararene-Based Two-Component Thixotropic Supramolecular Organogels: Complementarity and Multivalency as Prominent Motifs.

Chemistry (Weinheim an der Bergstrasse, Germany)

Zafrani Y, Kaizerman D, Hadar M, Bigan N, Granot E, Ghosh M, Adler-Abramovich L, Patolsky F, Cohen Y.
PMID: 29745993
Chemistry. 2018 Oct 22;24(59):15750-15755. doi: 10.1002/chem.201801418. Epub 2018 Jul 16.

Rationally designed two-component supramolecular organogels based on multiple chemical interactions between percarboxylato- and peramino-pillararenes are described. Mixing low concentration solutions (

Nucleon-nucleon interaction with nonlocal tensor contribution for the 3S1-3D1 state.

Physical review. C, Nuclear physics

Mustafa MM, Zahran ES.
PMID: 9955068
Phys Rev C Nucl Phys. 1988 Nov;38(5):2416-2423. doi: 10.1103/physrevc.38.2416.

No abstract available.

Design a robust sliding mode controller based on the state and parameter estimation for the nonlinear epidemiological model of Covid-19.

Nonlinear dynamics

Badfar E, Zaferani EJ, Nikoofard A.
PMID: 34776637
Nonlinear Dyn. 2021 Nov 08;1-14. doi: 10.1007/s11071-021-07036-4. Epub 2021 Nov 08.

In this research, the challenging problem of Covid-19 mitigation is looked at from an engineering point of view. At first, the behavior of coronavirus in the Iranian and Russian societies is expressed by a set of ordinary differential equations....

Immunomodulation of endothelial cells induced by macrolide therapy in a model of septic stimulation.

Immunity, inflammation and disease

Pons S, Arrii E, Arnaud M, Loiselle M, Ferry J, Nouacer M, Lion J, Cohen S, Mooney N, Zafrani L.
PMID: 34636179
Immun Inflamm Dis. 2021 Dec;9(4):1656-1669. doi: 10.1002/iid3.518. Epub 2021 Oct 12.

OBJECTIVES: Sepsis is defined as the host's inflammatory response to a life-threatening infection. The endothelium is implicated in immunoregulation during sepsis. Macrolides have been proposed to display immunomodulatory properties. The goal of this study was to analyze whether macrolides...

Gastrointestinal bleeding in critically ill immunocompromised patients.

Annals of intensive care

Catano J, Sacleux SC, Gornet JM, Camus M, Bigé N, Saliba F, Azoulay E, Dumas G, Zafrani L.
PMID: 34420114
Ann Intensive Care. 2021 Aug 21;11(1):130. doi: 10.1186/s13613-021-00913-6.

BACKGROUND: Acute gastrointestinal bleeding (GIB) may be a severe condition in immunocompromised patients and may require intensive care unit (ICU) admission. We aimed to describe the clinical spectrum of critically ill immunocompromised patients with GIB and identify risk factors...

ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients.

Annals of intensive care

Truche AS, Ragey SP, Souweine B, Bailly S, Zafrani L, Bouadma L, Clec'h C, Garrouste-Orgeas M, Lacave G, Schwebel C, Guebre-Egziabher F, Adrie C, Dumenil AS, Zaoui P, Argaud L, Jamali S, Goldran Toledano D, Marcotte G, Timsit JF, Darmon M.
PMID: 30560526
Ann Intensive Care. 2018 Dec 17;8(1):127. doi: 10.1186/s13613-018-0467-6.

BACKGROUND: Transient and persistent acute kidney injury (AKI) could share similar physiopathological mechanisms. The objective of our study was to assess prognostic impact of AKI duration on ICU mortality.DESIGN: Retrospective analysis of a prospective database via cause-specific model, with...

Interest and limits of assessing acute kidney injury in administrative dataset.

Annals of intensive care

Darmon M, Canet E, Zafrani L.
PMID: 31134361
Ann Intensive Care. 2019 May 27;9(1):60. doi: 10.1186/s13613-019-0535-6.

No abstract available.

Dynamic NMR study of the rotation around "biphenyl-type" bonds in polycyclic sulfoxides.

The Journal of organic chemistry

Braverman S, Zafrani Y, Gottlieb HE.
PMID: 12003536
J Org Chem. 2002 May 17;67(10):3277-83. doi: 10.1021/jo010947z.

In a recent paper, we reported on the base-catalyzed rearrangement of bis-propargylic sulfoxides that eventually leads to polycyclic products featuring an unsaturated, cyclic substituent such as cyclohexenyl or phenyl. Due to steric constraints, the latter is positioned roughly perpendicularly...

Acute kidney injury in patients with SARS-CoV-2 infection.

Annals of intensive care

Joseph A, Zafrani L, Mabrouki A, Azoulay E, Darmon M.
PMID: 32880774
Ann Intensive Care. 2020 Sep 03;10(1):117. doi: 10.1186/s13613-020-00734-z.

BACKGROUND: Acute Kidney Injury (AKI) is a frequent complication of severe SARS-CoV-2 infection. Multiple mechanisms are involved in COVID-19-associated AKI, from direct viral infection and secondary inflammation to complement activation and microthrombosis. However, data are limited in critically-ill patients....

Showing 1 to 12 of 52 entries