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On the Role of Dendritic Cells Versus Other Cells in Inducing Protective CD8+ T Cell Responses.

Frontiers in immunology

Zinkernagel RM.
PMID: 24575091
Front Immunol. 2014 Feb 10;5:30. doi: 10.3389/fimmu.2014.00030. eCollection 2014.

No abstract available.

Praxis

Adamo S, Gian Vital D, Zinkernagel AS, Kollias S, Steiner UC.
PMID: 29183214
Praxis (Bern 1994). 2017 Nov;106(24):1350-1353. doi: 10.1024/1661-8157/a002837.

No abstract available.

Bacterial pulmonary superinfections are associated with longer duration of ventilation in critically ill COVID-19 patients.

Cell reports. Medicine

Buehler PK, Zinkernagel AS, Hofmaenner DA, Wendel Garcia PD, Acevedo CT, Gómez-Mejia A, Mairpady Shambat S, Andreoni F, Maibach MA, Bartussek J, Hilty MP, Frey PM, Schuepbach RA, Brugger SD.
PMID: 33748789
Cell Rep Med. 2021 Apr 20;2(4):100229. doi: 10.1016/j.xcrm.2021.100229. Epub 2021 Mar 14.

The impact of secondary bacterial infections (superinfections) in coronavirus disease 2019 (COVID-19) is not well understood. In this prospective, monocentric cohort study, we aim to investigate the impact of superinfections in COVID-19 patients with acute respiratory distress syndrome. Patients...

Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19.

PLoS pathogens

Mairpady Shambat S, Gómez-Mejia A, Schweizer TA, Huemer M, Chang CC, Acevedo C, Bergada-Pijuan J, Vulin C, Hofmaenner DA, Scheier TC, Hertegonne S, Parietti E, Miroshnikova N, Wendel Garcia PD, Hilty MP, Buehler PK, Schuepbach RA, Brugger SD, Zinkernagel AS.
PMID: 35007290
PLoS Pathog. 2022 Jan 10;18(1):e1010176. doi: 10.1371/journal.ppat.1010176. Epub 2022 Jan 10.

COVID-19 displays diverse disease severities and symptoms including acute systemic inflammation and hypercytokinemia, with subsequent dysregulation of immune cells. Bacterial superinfections in COVID-19 can further complicate the disease course and are associated with increased mortality. However, there is limited...

A Multilab Replication of the Ego Depletion Effect.

Social psychological and personality science

Dang J, Barker P, Baumert A, Bentvelzen M, Berkman E, Buchholz N, Buczny J, Chen Z, De Cristofaro V, de Vries L, Dewitte S, Giacomantonio M, Gong R, Homan M, Imhoff R, Ismail I, Jia L, Kubiak T, Lange F, Li DY, Livingston J, Ludwig R, Panno A, Pearman J, Rassi N, Schiöth HB, Schmitt M, Sevincer AT, Shi J, Stamos A, Tan YC, Wenzel M, Zerhouni O, Zhang LW, Zhang YJ, Zinkernagel A.
PMID: 34113424
Soc Psychol Personal Sci. 2021 Jan 01;12(1):14-24. doi: 10.1177/1948550619887702. Epub 2020 Apr 03.

There is an active debate regarding whether the ego depletion effect is real. A recent preregistered experiment with the Stroop task as the depleting task and the antisaccade task as the outcome task found a medium-level effect size. In...

A Multilab Replication of the Ego Depletion Effect.

Social psychological and personality science

Dang J, Barker P, Baumert A, Bentvelzen M, Berkman E, Buchholz N, Buczny J, Chen Z, De Cristofaro V, de Vries L, Dewitte S, Giacomantonio M, Gong R, Homan M, Imhoff R, Ismail I, Jia L, Kubiak T, Lange F, Li DY, Livingston J, Ludwig R, Panno A, Pearman J, Rassi N, Schiöth HB, Schmitt M, Sevincer AT, Shi J, Stamos A, Tan YC, Wenzel M, Zerhouni O, Zhang LW, Zhang YJ, Zinkernagel A.
PMID: 34113424
Soc Psychol Personal Sci. 2021 Jan 01;12(1):14-24. doi: 10.1177/1948550619887702. Epub 2020 Apr 03.

There is an active debate regarding whether the ego depletion effect is real. A recent preregistered experiment with the Stroop task as the depleting task and the antisaccade task as the outcome task found a medium-level effect size. In...

Differentiation between Good and Low-Responders to Intravitreal Ranibizumab for Macular Edema Secondary to Retinal Vein Occlusion.

Journal of ophthalmology

Menke MN, Ebneter A, Zinkernagel MS, Wolf S.
PMID: 28044102
J Ophthalmol. 2016;2016:9875741. doi: 10.1155/2016/9875741. Epub 2016 Dec 01.

No abstract available.

Host-determined T cell fine specificity for self-H-2 in radiation bone-marrow chimeras of standard C57BL/6 (H-2(b)) mutantHz1 (H-2 (ba)), and F (1) mice.

Immunogenetics

Zinkernagel RM, Klein PA, Klein J.
PMID: 21302059
Immunogenetics. 1978 Dec;7(1):73-7. doi: 10.1007/BF01843990.

Reciprocal radiation bone-marrow chimeras were produced between the standard C57BL/6 (=B6) and the mutant B6.C-H-2 ( ba ) (=Hz1) strain. When infected with vaccinia virus, these chimeras, as well as an (Hz1 × B6)=→ Hz1 chimera, produced cytotoxic cells...

Comparison of Choroidal Thickness Measurements Using Spectral Domain Optical Coherence Tomography in Six Different Settings and With Customized Automated Segmentation Software.

Translational vision science & technology

Giannakaki-Zimmermann H, Huf W, Schaal KB, Schürch K, Dysli C, Dysli M, Zenger A, Ceklic L, Ciller C, Apostolopoulos S, De Zanet S, Sznitman R, Ebneter A, Zinkernagel MS, Wolf S, Munk MR.
PMID: 31110908
Transl Vis Sci Technol. 2019 May 02;8(3):5. doi: 10.1167/tvst.8.3.5. eCollection 2019 May.

PURPOSE: We investigate which spectral domain-optical coherence tomography (SD-OCT) setting is superior when measuring subfoveal choroidal thickness (CT) and compared results to an automated segmentation software.METHODS: Thirty patients underwent enhanced depth imaging (EDI)-OCT. B-scans were extracted in six different...

Machine Learning Can Predict Anti-VEGF Treatment Demand in a Treat-and-Extend Regimen for Patients with Neovascular AMD, DME, and RVO Associated Macular Edema.

Ophthalmology. Retina

Gallardo M, Munk MR, Kurmann T, De Zanet S, Mosinska A, Karagoz IK, Zinkernagel MS, Wolf S, Sznitman R.
PMID: 33971352
Ophthalmol Retina. 2021 Jul;5(7):604-624. doi: 10.1016/j.oret.2021.05.002. Epub 2021 May 08.

PURPOSE: To assess the potential of machine learning to predict low and high treatment demand in real life in patients with neovascular age-related macular degeneration (nAMD), retinal vein occlusion (RVO), and diabetic macular edema (DME) treated according to a...

Absence of Genotype/Phenotype Correlations Requires Molecular Diagnostic to Ascertain Stargardt and Stargardt-Like Swiss Patients.

Genes

Buhler VMM, Berger L, Schaller A, Zinkernagel MS, Wolf S, Escher P.
PMID: 34073554
Genes (Basel). 2021 May 26;12(6). doi: 10.3390/genes12060812.

We genetically characterized 22 Swiss patients who had been diagnosed with Stargardt disease after clinical examination. We identified in 11 patients (50%) pathogenic bi-allelic

LONGITUDINAL FOVEAL FLUORESCENCE LIFETIME CHARACTERISTICS IN GEOGRAPHIC ATROPHY USING FLUORESCENCE LIFETIME IMAGING OPHTHALMOSCOPY.

Retina (Philadelphia, Pa.)

Lincke JB, Dysli C, Jaggi D, Solberg Y, Wolf S, Zinkernagel MS.
PMID: 34282069
Retina. 2021 Nov 01;41(11):2391-2398. doi: 10.1097/IAE.0000000000003222.

PURPOSE: Short foveal fluorescence lifetimes (fFLT) in geographic atrophy are typically found in eyes with foveal sparing (FS) but may also occur in eyes without FS. We investigated whether short fFLT could serve as a functional biomarker for disease...

Showing 1 to 12 of 50 entries