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Showing 1 to 12 of 54 entries
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Health-resource use and costs associated with fibromyalgia in France, Germany, and the United States.

ClinicoEconomics and outcomes research : CEOR

Knight T, Schaefer C, Chandran A, Zlateva G, Winkelmann A, Perrot S.
PMID: 23637545
Clinicoecon Outcomes Res. 2013 Apr 23;5:171-80. doi: 10.2147/CEOR.S41111. Print 2013.

BACKGROUND: Fibromyalgia (FM) is a chronic disorder characterized by widespread, persistent pain. Prospective and retrospective studies have demonstrated substantial health-care costs associated with FM in a number of countries. This study evaluated and compared health-resource use (HRU) and associated...

Rapid reagent-less on-line H.

Talanta

Zlatev R, Stoytcheva M, Valdez B, Ramos R.
PMID: 28551151
Talanta. 2017 Aug 15;171:39-44. doi: 10.1016/j.talanta.2017.04.055. Epub 2017 Apr 26.

A simple, rapid, and reagent-less calorimetric method for H

Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging .

Biotechnology, biotechnological equipment

Bakalova R, Lazarova D, Nikolova B, Atanasova S, Zlateva G, Zhelev Z, Aoki I.
PMID: 26019630
Biotechnol Biotechnol Equip. 2015 Jan 02;29(1):175-180. doi: 10.1080/13102818.2014.984894. Epub 2014 Nov 26.

The present study was designed to investigate whether poly-ion complex hollow vesicles (polymersomes), based on chemically modified chitosan, are appropriate for passive tumour targeting in the context of their application as drug carriers. The experiments were performed on colon...

[Pathologic and anatomic considerations on tuberculosis in children 2-14 years of age].

Suvremenna meditsina

MIKHAILOV G, ZLATEVA MKh.
PMID: 13146531
Suvr Med (Sofiia). 1953;4(11):51-8.

No abstract available.

Joint assessment of intended and unintended effects of medications: an example using vascular endothelial growth factor inhibitors for neovascular age-related macular degeneration.

Journal of ophthalmology

Levy AR, Szabo S, Briggs A, Pleil A, Davie A, Zlateva G, Javitt J.
PMID: 20339464
J Ophthalmol. 2009;2009:540431. doi: 10.1155/2009/540431. Epub 2010 Feb 16.

Objective. To estimate the net health benefits of pegaptanib and ranibizumab by considering the impact of visual acuity and unintended effects (cardiovascular and hemorrhagic events) on quality-of-life among persons with neovascular age-related macular degeneration. Methods. We designed a probabilistic...

Simplifying Fibromyalgia Assessment: The VASFIQ Brief Symptom Scale.

Therapeutic advances in musculoskeletal disease

Boomershine CS, Emir B, Wang Y, Zlateva G.
PMID: 22870480
Ther Adv Musculoskelet Dis. 2011 Oct;3(5):215-26. doi: 10.1177/1759720X11416863.

OBJECTIVES: We tested the ability of the VASFIQ, a seven-item scale composed of Fibromyalgia Impact Questionnaire (FIQ) visual analog scales (VASs), to quantify fibromyalgia global disease severity and identify fibromyalgia patients with significant symptoms of fatigue, poor sleep, depression...

Effect of a Small Selective Inhibitor of C-Jun N-Terminal Kinase on the Inducible mRNA Expression of Interleukin-6 and Interleukin-18.

Open access Macedonian journal of medical sciences

Stanilova SA, Grigorov BG, Platikanova MS, Dobreva ZG.
PMID: 31456826
Open Access Maced J Med Sci. 2019 Jul 12;7(13):2062-2067. doi: 10.3889/oamjms.2019.567. eCollection 2019 Jul 15.

BACKGROUND: The expression of many inducible genes, involved in cell growth and differentiation as cytokine genes are regulated by receptor-activated intracellular signalling pathways, including the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase pathway.AIM: We examined the involvement of the...

Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment.

Dementia and geriatric cognitive disorders extra

Goukasian N, Porat S, Blanken A, Avila D, Zlatev D, Hurtz S, Hwang KS, Pierce J, Joshi SH, Woo E, Apostolova LG.
PMID: 31572424
Dement Geriatr Cogn Dis Extra. 2019 Aug 13;9(2):281-293. doi: 10.1159/000490044. eCollection 2019.

We analyzed structural magnetic resonance imaging data from 58 cognitively normal and 101 mild cognitive impairment subjects. We used a general linear regression model to study the association between cognitive performance with hippocampal atrophy and ventricular enlargement using the...

Effect of Alpha-tocopheryl Succinate on the Cytotoxicity of Anticancer Drugs Towards Leukemia Lymphocytes.

Anticancer research

Ivanova D, Zhelev Z, Zlateva G, Lazarova D, Yaneva Z, Panovska R, Aoki I, Bakalova R.
PMID: 34969764
Anticancer Res. 2022 Jan;42(1):547-554. doi: 10.21873/anticanres.15512.

BACKGROUND/AIM: This study analysed the effect of α-tocopheryl succinate (α-TS) on the redox-state of leukemia and normal lymphocytes, as well as their sensitization to fifteen anticancer drugs.MATERIALS AND METHODS: Cell viability was analyzed by trypan blue staining and automated...

Pharmacological Strategy for Selective Targeting of Glioblastoma by Redox-active Combination Drug - Comparison With the Chemotherapeutic Standard-of-care Temozolomide.

Anticancer research

Sumiyoshi A, Shibata S, Zhelev Z, Miller T, Lazarova D, Zlateva G, Aoki I, Bakalova R.
PMID: 34848461
Anticancer Res. 2021 Dec;41(12):6067-6076. doi: 10.21873/anticanres.15426.

BACKGROUND/AIM: We describe a pharmacological strategy for selectively targeting glioblastoma using a redox-active combination drug menadione/ascorbate (M/A), compared to the chemotherapeutic standard-of-care temozolomide (TMZ).MATERIALS AND METHODS: Experiments were conducted on glioblastoma mice (GS9L cell transplants - intracranial model), treated...

Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing.

Nucleic acids research

Jahns H, Degaonkar R, Podbevsek P, Gupta S, Bisbe A, Aluri K, Szeto J, Kumar P, LeBlanc S, Racie T, Brown CR, Castoreno A, Guenther DC, Jadhav V, Maier MA, Plavec J, Egli M, Manoharan M, Zlatev I.
PMID: 34508350
Nucleic Acids Res. 2021 Oct 11;49(18):10250-10264. doi: 10.1093/nar/gkab724.

In order to achieve efficient therapeutic post-transcriptional gene-silencing mediated by the RNA interference (RNAi) pathway, small interfering RNAs (siRNAs) must be chemically modified. Several supra-RNA structures, with the potential to stabilize siRNAs metabolically have been evaluated for their ability...

Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease.

Hypertension (Dallas, Tex. : 1979)

Bovée DM, Ren L, Uijl E, Clahsen-van Groningen MC, van Veghel R, Garrelds IM, Domenig O, Poglitsch M, Zlatev I, Kim JB, Huang S, Melton L, Lu X, Hoorn EJ, Foster D, Danser AHJ.
PMID: 33719507
Hypertension. 2021 May 05;77(5):1600-1612. doi: 10.1161/HYPERTENSIONAHA.120.16876. Epub 2021 Mar 15.

[Figure: see text].

Showing 1 to 12 of 54 entries