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β2-adrenergic stress evaluation of coronary endothelial-dependent vasodilator function in mice using (11)C-acetate micro-PET imaging of myocardial blood flow and oxidative metabolism.

EJNMMI research

Croteau E, Renaud JM, Archer C, Klein R, DaSilva JN, Ruddy TD, Beanlands RS, deKemp RA.
PMID: 25621195
EJNMMI Res. 2014 Dec 16;4(1):68. doi: 10.1186/s13550-014-0068-9. eCollection 2014 Dec.

BACKGROUND: Endothelial dysfunction is associated with vascular risk factors such as dyslipidemia, hypertension, and diabetes, leading to coronary atherosclerosis. Sympathetic stress using cold-pressor testing (CPT) has been used to measure coronary endothelial function in humans with positron emission tomography...

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Croteau E, Renaud JM, Archer C, et al. β2-adrenergic stress evaluation of coronary endothelial-dependent vasodilator function in mice using (11)C-acetate micro-PET imaging of myocardial blood flow and oxidative metabolism. EJNMMI Res. 2014;4(1):68doi: 10.1186/s13550-014-0068-9.
Croteau, E., Renaud, J. M., Archer, C., Klein, R., DaSilva, J. N., Ruddy, T. D., Beanlands, R. S., & deKemp, R. A. (2014). β2-adrenergic stress evaluation of coronary endothelial-dependent vasodilator function in mice using (11)C-acetate micro-PET imaging of myocardial blood flow and oxidative metabolism. EJNMMI research, 4(1), 68. https://doi.org/10.1186/s13550-014-0068-9
Croteau, Etienne, et al. "β2-adrenergic stress evaluation of coronary endothelial-dependent vasodilator function in mice using (11)C-acetate micro-PET imaging of myocardial blood flow and oxidative metabolism." EJNMMI research vol. 4,1 (2014): 68. doi: https://doi.org/10.1186/s13550-014-0068-9
Croteau E, Renaud JM, Archer C, Klein R, DaSilva JN, Ruddy TD, Beanlands RS, deKemp RA. β2-adrenergic stress evaluation of coronary endothelial-dependent vasodilator function in mice using (11)C-acetate micro-PET imaging of myocardial blood flow and oxidative metabolism. EJNMMI Res. 2014 Dec 16;4(1):68. doi: 10.1186/s13550-014-0068-9. eCollection 2014 Dec. PMID: 25621195; PMCID: PMC4293492.
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P- and N-Coordination of the Ambidentate Ligand HN[P(i-Pr).

Inorganic chemistry

Dickie DA, Chadha U, Kemp RA.
PMID: 28562029
Inorg Chem. 2017 Jun 19;56(12):7292-7300. doi: 10.1021/acs.inorgchem.7b01051. Epub 2017 May 31.

Five different coordination motifs were observed upon reaction of the simple group 13 Lewis acids MCl

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Dickie DA, Chadha U, Kemp RA. P- and N-Coordination of the Ambidentate Ligand HN[P(i-Pr). Inorg Chem. 2017;56(12):7292-7300doi: 10.1021/acs.inorgchem.7b01051.
Dickie, D. A., Chadha, U., & Kemp, R. A. (2017). P- and N-Coordination of the Ambidentate Ligand HN[P(i-Pr). Inorganic chemistry, 56(12), 7292-7300. https://doi.org/10.1021/acs.inorgchem.7b01051
Dickie, Diane A, et al. "P- and N-Coordination of the Ambidentate Ligand HN[P(i-Pr)." Inorganic chemistry vol. 56,12 (2017): 7292-7300. doi: https://doi.org/10.1021/acs.inorgchem.7b01051
Dickie DA, Chadha U, Kemp RA. P- and N-Coordination of the Ambidentate Ligand HN[P(i-Pr). Inorg Chem. 2017 Jun 19;56(12):7292-7300. doi: 10.1021/acs.inorgchem.7b01051. Epub 2017 May 31. PMID: 28562029.
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P,P-Diphenyl-N-(1,1,2,2-tetra-phenyl-1λ-diphosphanyl-idene)phosphinous amide.

Acta crystallographica. Section E, Structure reports online

Dickie DA, Kemp RA.
PMID: 21203164
Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 09;64:o1449. doi: 10.1107/S1600536808020412.

The title compound, C(36)H(30)NP(3), a structural isomer of tris-(diphenyl-phosphino)amine, was unexpectedly isolated as the sole phospho-rus-containing product from the reaction of Mg[N(PPh(2))(2)](2)(THF)(2) (THF is tetra-hydro-furan) with CO(2). Its identity was confirmed by (31)P NMR spectroscopy and single-crystal X-ray diffraction....

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Dickie DA, Kemp RA. P,P-Diphenyl-N-(1,1,2,2-tetra-phenyl-1λ-diphosphanyl-idene)phosphinous amide. Acta Crystallogr Sect E Struct Rep Online. 2008;64:o1449doi: 10.1107/S1600536808020412.
Dickie, D. A., & Kemp, R. A. (2008). P,P-Diphenyl-N-(1,1,2,2-tetra-phenyl-1λ-diphosphanyl-idene)phosphinous amide. Acta crystallographica. Section E, Structure reports online, 64o1449. https://doi.org/10.1107/S1600536808020412
Dickie, Diane A, and Kemp, Richard A. "P,P-Diphenyl-N-(1,1,2,2-tetra-phenyl-1λ-diphosphanyl-idene)phosphinous amide." Acta crystallographica. Section E, Structure reports online vol. 64 (2008): o1449. doi: https://doi.org/10.1107/S1600536808020412
Dickie DA, Kemp RA. P,P-Diphenyl-N-(1,1,2,2-tetra-phenyl-1λ-diphosphanyl-idene)phosphinous amide. Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 09;64:o1449. doi: 10.1107/S1600536808020412. PMID: 21203164; PMCID: PMC2962250.
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NH/PH isomerization and a Lewis pair for carbon dioxide capture.

Inorganic chemistry

Barry BM, Dickie DA, Murphy LJ, Clyburne JA, Kemp RA.
PMID: 23879626
Inorg Chem. 2013 Aug 05;52(15):8312-4. doi: 10.1021/ic401498r. Epub 2013 Jul 23.

Bis(di-i-propylphosphino)amine 1 reacts with B(C6F5)3 to form an adduct with concomitant N/P H-isomerization. This species reacts smoothly with carbon dioxide. An attempt to prepare an anionic derivative resulted in the formation of a novel heterocycle derived from the PNP...

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Barry BM, Dickie DA, Murphy LJ, et al. NH/PH isomerization and a Lewis pair for carbon dioxide capture. Inorg Chem. 2013;52(15):8312-4doi: 10.1021/ic401498r.
Barry, B. M., Dickie, D. A., Murphy, L. J., Clyburne, J. A., & Kemp, R. A. (2013). NH/PH isomerization and a Lewis pair for carbon dioxide capture. Inorganic chemistry, 52(15), 8312-4. https://doi.org/10.1021/ic401498r
Barry, Brian M, et al. "NH/PH isomerization and a Lewis pair for carbon dioxide capture." Inorganic chemistry vol. 52,15 (2013): 8312-4. doi: https://doi.org/10.1021/ic401498r
Barry BM, Dickie DA, Murphy LJ, Clyburne JA, Kemp RA. NH/PH isomerization and a Lewis pair for carbon dioxide capture. Inorg Chem. 2013 Aug 05;52(15):8312-4. doi: 10.1021/ic401498r. Epub 2013 Jul 23. PMID: 23879626.
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Metal complexes (M = Zn, Sn, and Pb) of 2-phosphinobenzenethiolates: insights into ligand folding and hemilability.

Inorganic chemistry

Barry BM, Stein BW, Larsen CA, Wirtz MN, Geiger WE, Waterman R, Kemp RA.
PMID: 23937328
Inorg Chem. 2013 Sep 03;52(17):9875-84. doi: 10.1021/ic400990n. Epub 2013 Aug 12.

The divalent metal complexes M(II){(SC6H4-2-PR2)-κ(2)S,P}2 (3-7, and 9-11) (M = Zn, Sn, or Pb; R = (i)Pr, (t)Bu, or Ph), the Sn(IV) complexes Sn{(SC6H4-2-PR2)-κ(2)-S,P}Ph2Cl (12 and 13) (R = (i)Pr and (t)Bu), and the ionic Sn(IV) complexes [Sn{(SC6H4-2-PR2)-κ(2)-S,P}Ph2][BPh4] (14...

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Barry BM, Stein BW, Larsen CA, et al. Metal complexes (M = Zn, Sn, and Pb) of 2-phosphinobenzenethiolates: insights into ligand folding and hemilability. Inorg Chem. 2013;52(17):9875-84doi: 10.1021/ic400990n.
Barry, B. M., Stein, B. W., Larsen, C. A., Wirtz, M. N., Geiger, W. E., Waterman, R., & Kemp, R. A. (2013). Metal complexes (M = Zn, Sn, and Pb) of 2-phosphinobenzenethiolates: insights into ligand folding and hemilability. Inorganic chemistry, 52(17), 9875-84. https://doi.org/10.1021/ic400990n
Barry, Brian M, et al. "Metal complexes (M = Zn, Sn, and Pb) of 2-phosphinobenzenethiolates: insights into ligand folding and hemilability." Inorganic chemistry vol. 52,17 (2013): 9875-84. doi: https://doi.org/10.1021/ic400990n
Barry BM, Stein BW, Larsen CA, Wirtz MN, Geiger WE, Waterman R, Kemp RA. Metal complexes (M = Zn, Sn, and Pb) of 2-phosphinobenzenethiolates: insights into ligand folding and hemilability. Inorg Chem. 2013 Sep 03;52(17):9875-84. doi: 10.1021/ic400990n. Epub 2013 Aug 12. PMID: 23937328.
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Synthesis and Characterization of Structurally Diverse Alkaline-Earth Salen Compounds for Subterranean Fluid Flow Tracking.

Inorganic chemistry

Boyle TJ, Sears JM, Greathouse JA, Perales D, Cramer R, Staples O, Rheingold AL, Coker EN, Roper TM, Kemp RA.
PMID: 29431993
Inorg Chem. 2018 Mar 05;57(5):2402-2415. doi: 10.1021/acs.inorgchem.7b01350. Epub 2018 Feb 12.

A family of magnesium and calcium salen-derivatives was synthesized and characterized for use as subterranean fluid flow monitors. For the Mg complexes, di- n-butyl magnesium ([Mg(Bu

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Boyle TJ, Sears JM, Greathouse JA, et al. Synthesis and Characterization of Structurally Diverse Alkaline-Earth Salen Compounds for Subterranean Fluid Flow Tracking. Inorg Chem. 2018;57(5):2402-2415doi: 10.1021/acs.inorgchem.7b01350.
Boyle, T. J., Sears, J. M., Greathouse, J. A., Perales, D., Cramer, R., Staples, O., Rheingold, A. L., Coker, E. N., Roper, T. M., & Kemp, R. A. (2018). Synthesis and Characterization of Structurally Diverse Alkaline-Earth Salen Compounds for Subterranean Fluid Flow Tracking. Inorganic chemistry, 57(5), 2402-2415. https://doi.org/10.1021/acs.inorgchem.7b01350
Boyle, Timothy J, et al. "Synthesis and Characterization of Structurally Diverse Alkaline-Earth Salen Compounds for Subterranean Fluid Flow Tracking." Inorganic chemistry vol. 57,5 (2018): 2402-2415. doi: https://doi.org/10.1021/acs.inorgchem.7b01350
Boyle TJ, Sears JM, Greathouse JA, Perales D, Cramer R, Staples O, Rheingold AL, Coker EN, Roper TM, Kemp RA. Synthesis and Characterization of Structurally Diverse Alkaline-Earth Salen Compounds for Subterranean Fluid Flow Tracking. Inorg Chem. 2018 Mar 05;57(5):2402-2415. doi: 10.1021/acs.inorgchem.7b01350. Epub 2018 Feb 12. PMID: 29431993.
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Our work as health professionals: "With Great Power Comes Great Responsibility" [Stan Lee].

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

deKemp RA.
PMID: 32651800
J Nucl Cardiol. 2020 Aug;27(4):1087-1088. doi: 10.1007/s12350-020-02270-6. Epub 2020 Jul 10.

No abstract available.

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deKemp RA. Our work as health professionals: "With Great Power Comes Great Responsibility" [Stan Lee]. J Nucl Cardiol. 2020;27(4):1087-1088doi: 10.1007/s12350-020-02270-6.
deKemp, R. A. (2020). Our work as health professionals: "With Great Power Comes Great Responsibility" [Stan Lee]. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 27(4), 1087-1088. https://doi.org/10.1007/s12350-020-02270-6
deKemp, Robert A. "Our work as health professionals: "With Great Power Comes Great Responsibility" [Stan Lee]." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. 27,4 (2020): 1087-1088. doi: https://doi.org/10.1007/s12350-020-02270-6
deKemp RA. Our work as health professionals: "With Great Power Comes Great Responsibility" [Stan Lee]. J Nucl Cardiol. 2020 Aug;27(4):1087-1088. doi: 10.1007/s12350-020-02270-6. Epub 2020 Jul 10. PMID: 32651800.
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Persistent Lung Inflammation After Clinical Resolution of Community-Acquired Pneumonia as Measured by .

Chest

Corrales-Medina VF, deKemp RA, Chirinos JA, Zeng W, Wang J, Waterer G, Beanlands RSB, Dwivedi G.
PMID: 33667494
Chest. 2021 Aug;160(2):446-453. doi: 10.1016/j.chest.2021.02.048. Epub 2021 Mar 03.

BACKGROUND: Survivors of community-acquired pneumonia (CAP) are at increased risk of cardiovascular disease, cognitive and functional decline, and death, but the mechanisms remain unknown.RESEARCH QUESTION: Do CAP survivors have evidence of increased inflammatory activity in their lung parenchyma on...

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Corrales-Medina VF, deKemp RA, Chirinos JA, et al. Persistent Lung Inflammation After Clinical Resolution of Community-Acquired Pneumonia as Measured by . Chest. 2021;160(2):446-453doi: 10.1016/j.chest.2021.02.048.
Corrales-Medina, V. F., deKemp, R. A., Chirinos, J. A., Zeng, W., Wang, J., Waterer, G., Beanlands, R. S. B., & Dwivedi, G. (2021). Persistent Lung Inflammation After Clinical Resolution of Community-Acquired Pneumonia as Measured by . Chest, 160(2), 446-453. https://doi.org/10.1016/j.chest.2021.02.048
Corrales-Medina, Vicente F, et al. "Persistent Lung Inflammation After Clinical Resolution of Community-Acquired Pneumonia as Measured by ." Chest vol. 160,2 (2021): 446-453. doi: https://doi.org/10.1016/j.chest.2021.02.048
Corrales-Medina VF, deKemp RA, Chirinos JA, Zeng W, Wang J, Waterer G, Beanlands RSB, Dwivedi G. Persistent Lung Inflammation After Clinical Resolution of Community-Acquired Pneumonia as Measured by . Chest. 2021 Aug;160(2):446-453. doi: 10.1016/j.chest.2021.02.048. Epub 2021 Mar 03. PMID: 33667494.
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Internal validation of myocardial flow reserve PET imaging using stress/rest myocardial activity ratios with Rb-82 and N-13-ammonia.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Juneau D, Wu KY, Kaps N, Yao J, Renaud JM, Beanlands RSB, Ruddy TD, deKemp RA.
PMID: 33389638
J Nucl Cardiol. 2021 Jun;28(3):835-850. doi: 10.1007/s12350-020-02464-y. Epub 2021 Jan 03.

BACKGROUND: Myocardial flow reserve (MFR) measurement provides incremental diagnostic and prognostic information. The objective of the current study was to investigate the application of a simplified model for the estimation of MFR using only the stress/rest myocardial activity ratio...

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Juneau D, Wu KY, Kaps N, et al. Internal validation of myocardial flow reserve PET imaging using stress/rest myocardial activity ratios with Rb-82 and N-13-ammonia. J Nucl Cardiol. 2021;28(3):835-850doi: 10.1007/s12350-020-02464-y.
Juneau, D., Wu, K. Y., Kaps, N., Yao, J., Renaud, J. M., Beanlands, R. S. B., Ruddy, T. D., & deKemp, R. A. (2021). Internal validation of myocardial flow reserve PET imaging using stress/rest myocardial activity ratios with Rb-82 and N-13-ammonia. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 28(3), 835-850. https://doi.org/10.1007/s12350-020-02464-y
Juneau, Daniel, et al. "Internal validation of myocardial flow reserve PET imaging using stress/rest myocardial activity ratios with Rb-82 and N-13-ammonia." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. 28,3 (2021): 835-850. doi: https://doi.org/10.1007/s12350-020-02464-y
Juneau D, Wu KY, Kaps N, Yao J, Renaud JM, Beanlands RSB, Ruddy TD, deKemp RA. Internal validation of myocardial flow reserve PET imaging using stress/rest myocardial activity ratios with Rb-82 and N-13-ammonia. J Nucl Cardiol. 2021 Jun;28(3):835-850. doi: 10.1007/s12350-020-02464-y. Epub 2021 Jan 03. PMID: 33389638.
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Site qualification and clinical interpretation standards for .

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Renaud JM, Premaratne M, Villeneuve MC, Finnerty V, Harel F, Heinonen T, Tardif JC, Ruddy TD, deKemp RA.
PMID: 32185684
J Nucl Cardiol. 2021 Dec;28(6):2712-2725. doi: 10.1007/s12350-020-02100-9. Epub 2020 Mar 17.

BACKGROUND: Qualification and interpretation standards are essential for establishing METHODS: Rest-stress RESULTS: Phantom scans: visual scoring confirmed RCA-ischemia on all cameras. Regional SSS, SDS agreement was moderate to very good: ICC-r = 0.57, 0.84. Patient scans: 90% of global...

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Renaud JM, Premaratne M, Villeneuve MC, et al. Site qualification and clinical interpretation standards for . J Nucl Cardiol. 2020;28(6):2712-2725doi: 10.1007/s12350-020-02100-9.
Renaud, J. M., Premaratne, M., Villeneuve, M. C., Finnerty, V., Harel, F., Heinonen, T., Tardif, J. C., Ruddy, T. D., & deKemp, R. A. (2021). Site qualification and clinical interpretation standards for . Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 28(6), 2712-2725. https://doi.org/10.1007/s12350-020-02100-9
Renaud, Jennifer M, et al. "Site qualification and clinical interpretation standards for ." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. 28,6 (2021): 2712-2725. doi: https://doi.org/10.1007/s12350-020-02100-9
Renaud JM, Premaratne M, Villeneuve MC, Finnerty V, Harel F, Heinonen T, Tardif JC, Ruddy TD, deKemp RA. Site qualification and clinical interpretation standards for . J Nucl Cardiol. 2021 Dec;28(6):2712-2725. doi: 10.1007/s12350-020-02100-9. Epub 2020 Mar 17. PMID: 32185684.
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Increased myocardial oxygen consumption rates are associated with maladaptive right ventricular remodeling and decreased event-free survival in heart failure patients.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Ahmadi A, Renaud JM, Promislow S, Burwash IG, Dwivedi G, Klein R, Zelt JGE, deKemp RA, Beanlands RS, Mielniczuk LM.
PMID: 32383088
J Nucl Cardiol. 2021 Dec;28(6):2784-2795. doi: 10.1007/s12350-020-02144-x. Epub 2020 May 07.

BACKGROUND: Reduced left ventricular (LV) function is associated with increased myocardial oxygen consumption rate (MVOMETHODS AND RESULTS: 33 patients with left heart failure were assessed for RV function/size using echocardiography. Positron emission tomography (PET) was used to measure CONCLUSIONS:...

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Ahmadi A, Renaud JM, Promislow S, et al. Increased myocardial oxygen consumption rates are associated with maladaptive right ventricular remodeling and decreased event-free survival in heart failure patients. J Nucl Cardiol. 2020;28(6):2784-2795doi: 10.1007/s12350-020-02144-x.
Ahmadi, A., Renaud, J. M., Promislow, S., Burwash, I. G., Dwivedi, G., Klein, R., Zelt, J. G. E., deKemp, R. A., Beanlands, R. S., & Mielniczuk, L. M. (2021). Increased myocardial oxygen consumption rates are associated with maladaptive right ventricular remodeling and decreased event-free survival in heart failure patients. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 28(6), 2784-2795. https://doi.org/10.1007/s12350-020-02144-x
Ahmadi, Ali, et al. "Increased myocardial oxygen consumption rates are associated with maladaptive right ventricular remodeling and decreased event-free survival in heart failure patients." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. 28,6 (2021): 2784-2795. doi: https://doi.org/10.1007/s12350-020-02144-x
Ahmadi A, Renaud JM, Promislow S, Burwash IG, Dwivedi G, Klein R, Zelt JGE, deKemp RA, Beanlands RS, Mielniczuk LM. Increased myocardial oxygen consumption rates are associated with maladaptive right ventricular remodeling and decreased event-free survival in heart failure patients. J Nucl Cardiol. 2021 Dec;28(6):2784-2795. doi: 10.1007/s12350-020-02144-x. Epub 2020 May 07. PMID: 32383088.
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Reproducible Quantification of Regional Sympathetic Denervation with [.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Wang JZ, Moody JB, Kaps N, Britt D, Lavallee A, Renaud JM, Zelt JGE, Wu KY, Beanlands RS, Fallavollita JA, Canty JM, deKemp RA.
PMID: 32347526
J Nucl Cardiol. 2020 Apr 28; doi: 10.1007/s12350-020-02114-3. Epub 2020 Apr 28.

BACKGROUND: Regional cardiac sympathetic denervation is predictive of sudden cardiac arrest in patients with ischemic cardiomyopathy. The reproducibility of denervation scores between automated software programs has not been evaluated. This study seeks to (1) compare the inter-rater reliability of...

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Wang JZ, Moody JB, Kaps N, et al. Reproducible Quantification of Regional Sympathetic Denervation with [. J Nucl Cardiol. 2020;doi: 10.1007/s12350-020-02114-3.
Wang, J. Z., Moody, J. B., Kaps, N., Britt, D., Lavallee, A., Renaud, J. M., Zelt, J. G. E., Wu, K. Y., Beanlands, R. S., Fallavollita, J. A., Canty, J. M., & deKemp, R. A. (2020). Reproducible Quantification of Regional Sympathetic Denervation with [. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, . https://doi.org/10.1007/s12350-020-02114-3
Wang, Jean Z, et al. "Reproducible Quantification of Regional Sympathetic Denervation with [." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. (2020). doi: https://doi.org/10.1007/s12350-020-02114-3
Wang JZ, Moody JB, Kaps N, Britt D, Lavallee A, Renaud JM, Zelt JGE, Wu KY, Beanlands RS, Fallavollita JA, Canty JM, deKemp RA. Reproducible Quantification of Regional Sympathetic Denervation with [. J Nucl Cardiol. 2020 Apr 28; doi: 10.1007/s12350-020-02114-3. Epub 2020 Apr 28. PMID: 32347526; PMCID: PMC7673573.
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