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The interplay between tectonics, sediment dynamics and gateways evolution in the Danube system from the Pannonian Basin to the western Black Sea.

The Science of the total environment

Matenco L, Munteanu I, Ter Borgh M, Stanica A, Tilita M, Lericolais G, Dinu C, Oaie G.
PMID: 26524991
Sci Total Environ. 2016 Feb 01;543:807-827. doi: 10.1016/j.scitotenv.2015.10.081. Epub 2015 Oct 31.

Understanding the natural evolution of a river-delta-sea system is important to develop a strong scientific basis for efficient integrated management plans. The distribution of sediment fluxes is linked with the natural connection between sediment source areas situated in uplifting...

Immune composition and its association with hematologic recovery after chemotherapeutic injury in acute myeloid leukemia.

Experimental hematology

Kenswil KJG, Pisterzi P, Feyen J, Ter Borg M, Rombouts E, Braakman E, Raaijmakers MHGP.
PMID: 34800603
Exp Hematol. 2022 Jan;105:32-38.e2. doi: 10.1016/j.exphem.2021.11.003. Epub 2021 Nov 17.

Chemotherapy-induced bone marrow (BM) injury is a significant cause of morbidity and mortality in acute myeloid leukemia (AML). Time to hematologic recovery after standard ("7 + 3") myeloablative chemotherapy can vary considerably among patients, but the factors that drive...

Evaluation of Nutri-Score in Relation to Dietary Guidelines and Food Reformulation in The Netherlands.

Nutrients

Ter Borg S, Steenbergen E, Milder IEJ, Temme EHM.
PMID: 34960088
Nutrients. 2021 Dec 17;13(12). doi: 10.3390/nu13124536.

An unhealthy dietary pattern is an important risk factor for non-communicable diseases. Front-of-Pack nutritional labels such as Nutri-Score can be used to improve food choices. In addition, products can be improved through reformulation. The current study investigates to what...

Evaluation of Nutri-Score in Relation to Dietary Guidelines and Food Reformulation in The Netherlands.

Nutrients

Ter Borg S, Steenbergen E, Milder IEJ, Temme EHM.
PMID: 34960088
Nutrients. 2021 Dec 17;13(12). doi: 10.3390/nu13124536.

An unhealthy dietary pattern is an important risk factor for non-communicable diseases. Front-of-Pack nutritional labels such as Nutri-Score can be used to improve food choices. In addition, products can be improved through reformulation. The current study investigates to what...

Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.

The Journal of biological chemistry

Sørensen G, Rickhag M, Leo D, Lycas MD, Ridderstrøm PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wörtwein G, Gainetdinov RR, Fink-Jensen A, Gether U.
PMID: 34756883
J Biol Chem. 2021 Oct 29;297(6):101361. doi: 10.1016/j.jbc.2021.101361. Epub 2021 Oct 29.

The dopamine (DA) transporter (DAT) is part of a presynaptic multiprotein network involving interactions with scaffold proteins via its C-terminal PDZ domain-binding sequence. Using a mouse model expressing DAT with mutated PDZ-binding sequence (DAT-AAA), we previously demonstrated the importance...

Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.

The Journal of biological chemistry

Sørensen G, Rickhag M, Leo D, Lycas MD, Ridderstrøm PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wörtwein G, Gainetdinov RR, Fink-Jensen A, Gether U.
PMID: 34756883
J Biol Chem. 2021 Oct 29;297(6):101361. doi: 10.1016/j.jbc.2021.101361. Epub 2021 Oct 29.

The dopamine (DA) transporter (DAT) is part of a presynaptic multiprotein network involving interactions with scaffold proteins via its C-terminal PDZ domain-binding sequence. Using a mouse model expressing DAT with mutated PDZ-binding sequence (DAT-AAA), we previously demonstrated the importance...

Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.

The Journal of biological chemistry

Sørensen G, Rickhag M, Leo D, Lycas MD, Ridderstrøm PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wörtwein G, Gainetdinov RR, Fink-Jensen A, Gether U.
PMID: 34756883
J Biol Chem. 2021 Oct 29;297(6):101361. doi: 10.1016/j.jbc.2021.101361. Epub 2021 Oct 29.

The dopamine (DA) transporter (DAT) is part of a presynaptic multiprotein network involving interactions with scaffold proteins via its C-terminal PDZ domain-binding sequence. Using a mouse model expressing DAT with mutated PDZ-binding sequence (DAT-AAA), we previously demonstrated the importance...

High practice variation in risk stratification, baseline oncological staging, and follow-up strategies for T1 colorectal cancers in the Netherlands.

Endoscopy international open

Gijsbers K, de Graaf W, Moons LMG, Ter Borg F.
PMID: 32904821
Endosc Int Open. 2020 Sep;8(9):E1117-E1122. doi: 10.1055/a-1192-3545. Epub 2020 Aug 31.

No abstract available.

Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease.

JCI insight

Herborg F, Jensen KL, Tolstoy S, Arends NV, Posselt LP, Shekar A, Aguilar JI, Lund VK, Erreger K, Rickhag M, Lycas MD, Lonsdale MN, Rahbek-Clemmensen T, Sørensen AT, Newman AH, Løkkegaard A, Kjærulff O, Werge T, Møller LB, Matthies HJ, Galli A, Hjermind LE, Gether U.
PMID: 34375312
JCI Insight. 2021 Sep 22;6(18). doi: 10.1172/jci.insight.151496.

Dysfunctional dopaminergic neurotransmission is central to movement disorders and mental diseases. The dopamine transporter (DAT) regulates extracellular dopamine levels, but the genetic and mechanistic link between DAT function and dopamine-related pathologies is not clear. Particularly, the pathophysiological significance of...

Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.

The Journal of biological chemistry

Sørensen G, Rickhag M, Leo D, Lycas MD, Ridderstrøm PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wörtwein G, Gainetdinov RR, Fink-Jensen A, Gether U.
PMID: 34756883
J Biol Chem. 2021 Oct 29;297(6):101361. doi: 10.1016/j.jbc.2021.101361. Epub 2021 Oct 29.

The dopamine (DA) transporter (DAT) is part of a presynaptic multiprotein network involving interactions with scaffold proteins via its C-terminal PDZ domain-binding sequence. Using a mouse model expressing DAT with mutated PDZ-binding sequence (DAT-AAA), we previously demonstrated the importance...

The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells.

Leukemia

Thijssen R, Ter Burg J, van Bochove GG, de Rooij MF, Kuil A, Jansen MH, Kuijpers TW, Baars JW, Virone-Oddos A, Spaargaren M, Egile C, van Oers MH, Eldering E, Kersten MJ, Kater AP.
PMID: 27600169
Leukemia. 2016 Sep;30(9):1963. doi: 10.1038/leu.2016.184.

No abstract available.

Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.

The Journal of biological chemistry

Sørensen G, Rickhag M, Leo D, Lycas MD, Ridderstrøm PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wörtwein G, Gainetdinov RR, Fink-Jensen A, Gether U.
PMID: 34756883
J Biol Chem. 2021 Oct 29;297(6):101361. doi: 10.1016/j.jbc.2021.101361. Epub 2021 Oct 29.

The dopamine (DA) transporter (DAT) is part of a presynaptic multiprotein network involving interactions with scaffold proteins via its C-terminal PDZ domain-binding sequence. Using a mouse model expressing DAT with mutated PDZ-binding sequence (DAT-AAA), we previously demonstrated the importance...

Showing 1 to 12 of 50 entries