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Showing 1 to 12 of 194 entries
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Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population.

The Journal of frailty & aging

Aarts S, Patel KV, Garcia ME, Van den Akker M, Verhey FR, Metsemakers JF, Van Boxtel MP, Gudnason V, Jonsdottir MK, Siggeirsdottir K, Jonsson PV, Harris TB, Launer LJ.
PMID: 27030941
J Frailty Aging. 2015;4(3):131-8. doi: 10.14283/jfa.2015.45.

BACKGROUND: Frailty is often associated with multimorbidity and disability.OBJECTIVES: We investigated heterogeneity in the frail older population by characterizing five subpopulations according to quantitative biological markers, multimorbidity and disability, and examined their association with mortality and nursing home admission.DESIGN:...

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Aarts S, Patel KV, Garcia ME, et al. Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population. J Frailty Aging. 2015;4(3):131-8doi: 10.14283/jfa.2015.45.
Aarts, S., Patel, K. V., Garcia, M. E., Van den Akker, M., Verhey, F. R., Metsemakers, J. F., Van Boxtel, M. P., Gudnason, V., Jonsdottir, M. K., Siggeirsdottir, K., Jonsson, P. V., Harris, T. B., & Launer, L. J. (2015). Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population. The Journal of frailty & aging, 4(3), 131-8. https://doi.org/10.14283/jfa.2015.45
Aarts, S, et al. "Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population." The Journal of frailty & aging vol. 4,3 (2015): 131-8. doi: https://doi.org/10.14283/jfa.2015.45
Aarts S, Patel KV, Garcia ME, Van den Akker M, Verhey FR, Metsemakers JF, Van Boxtel MP, Gudnason V, Jonsdottir MK, Siggeirsdottir K, Jonsson PV, Harris TB, Launer LJ. Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population. J Frailty Aging. 2015;4(3):131-8. doi: 10.14283/jfa.2015.45. PMID: 27030941; PMCID: PMC5367922.
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Global surgery and the dilemma for obstetricians.

Lancet (London, England)

Rijken MJ, Meguid T, van den Akker T, van Roosmalen J, Stekelenburg J.
PMID: 26841745
Lancet. 2015 Nov 14;386(10007):1941-1942. doi: 10.1016/S0140-6736(15)00828-4. Epub 2015 Nov 13.

No abstract available.

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Rijken MJ, Meguid T, van den Akker T, et al. Global surgery and the dilemma for obstetricians. Lancet. 2015;386(10007):1941-1942doi: 10.1016/S0140-6736(15)00828-4.
Rijken, M. J., Meguid, T., van den Akker, T., van Roosmalen, J., Stekelenburg, J. (2015). Global surgery and the dilemma for obstetricians. Lancet (London, England), 386(10007), 1941-1942. https://doi.org/10.1016/S0140-6736(15)00828-4
Rijken, Marcus J, et al. "Global surgery and the dilemma for obstetricians." Lancet (London, England) vol. 386,10007 (2015): 1941-1942. doi: https://doi.org/10.1016/S0140-6736(15)00828-4
Rijken MJ, Meguid T, van den Akker T, van Roosmalen J, Stekelenburg J. Global surgery and the dilemma for obstetricians. Lancet. 2015 Nov 14;386(10007):1941-1942. doi: 10.1016/S0140-6736(15)00828-4. Epub 2015 Nov 13. PMID: 26841745.
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Gene analysis for longitudinal family data using random-effects models.

BMC proceedings

Houwing-Duistermaat JJ, Helmer Q, Balliu B, van den Akker E, Tsonaka R, Uh HW.
PMID: 25519415
BMC Proc. 2014 Jun 17;8:S88. doi: 10.1186/1753-6561-8-S1-S88. eCollection 2014.

We have extended our recently developed 2-step approach for gene-based analysis to the family design and to the analysis of rare variants. The goal of this approach is to study the joint effect of multiple single-nucleotide polymorphisms that belong...

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Houwing-Duistermaat JJ, Helmer Q, Balliu B, et al. Gene analysis for longitudinal family data using random-effects models. BMC Proc. 2014;8:S88doi: 10.1186/1753-6561-8-S1-S88.
Houwing-Duistermaat, J. J., Helmer, Q., Balliu, B., van den Akker, E., Tsonaka, R., & Uh, H. W. (2014). Gene analysis for longitudinal family data using random-effects models. BMC proceedings, 8S88. https://doi.org/10.1186/1753-6561-8-S1-S88
Houwing-Duistermaat, Jeanine J, et al. "Gene analysis for longitudinal family data using random-effects models." BMC proceedings vol. 8 (2014): S88. doi: https://doi.org/10.1186/1753-6561-8-S1-S88
Houwing-Duistermaat JJ, Helmer Q, Balliu B, van den Akker E, Tsonaka R, Uh HW. Gene analysis for longitudinal family data using random-effects models. BMC Proc. 2014 Jun 17;8:S88. doi: 10.1186/1753-6561-8-S1-S88. eCollection 2014. PMID: 25519415; PMCID: PMC4143685.
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Elusive sources of variability of dystrophin rescue by exon skipping.

Skeletal muscle

Vila MC, Klimek MB, Novak JS, Rayavarapu S, Uaesoontrachoon K, Boehler JF, Fiorillo AA, Hogarth MW, Zhang A, Shaughnessy C, Gordish-Dressman H, Burki U, Straub V, Lu QL, Partridge TA, Brown KJ, Hathout Y, van den Anker J, Hoffman EP, Nagaraju K.
PMID: 26634117
Skelet Muscle. 2015 Dec 01;5:44. doi: 10.1186/s13395-015-0070-6. eCollection 2015.

BACKGROUND: Systemic delivery of anti-sense oligonucleotides to Duchenne muscular dystrophy (DMD) patients to induce de novo dystrophin protein expression in muscle (exon skipping) is a promising therapy. Treatment with Phosphorodiamidate morpholino oligomers (PMO) lead to shorter de novo dystrophin...

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Vila MC, Klimek MB, Novak JS, et al. Elusive sources of variability of dystrophin rescue by exon skipping. Skelet Muscle. 2015;5:44doi: 10.1186/s13395-015-0070-6.
Vila, M. C., Klimek, M. B., Novak, J. S., Rayavarapu, S., Uaesoontrachoon, K., Boehler, J. F., Fiorillo, A. A., Hogarth, M. W., Zhang, A., Shaughnessy, C., Gordish-Dressman, H., Burki, U., Straub, V., Lu, Q. L., Partridge, T. A., Brown, K. J., Hathout, Y., van den Anker, J., Hoffman, E. P., & Nagaraju, K. (2015). Elusive sources of variability of dystrophin rescue by exon skipping. Skeletal muscle, 544. https://doi.org/10.1186/s13395-015-0070-6
Vila, Maria Candida, et al. "Elusive sources of variability of dystrophin rescue by exon skipping." Skeletal muscle vol. 5 (2015): 44. doi: https://doi.org/10.1186/s13395-015-0070-6
Vila MC, Klimek MB, Novak JS, Rayavarapu S, Uaesoontrachoon K, Boehler JF, Fiorillo AA, Hogarth MW, Zhang A, Shaughnessy C, Gordish-Dressman H, Burki U, Straub V, Lu QL, Partridge TA, Brown KJ, Hathout Y, van den Anker J, Hoffman EP, Nagaraju K. Elusive sources of variability of dystrophin rescue by exon skipping. Skelet Muscle. 2015 Dec 01;5:44. doi: 10.1186/s13395-015-0070-6. eCollection 2015. PMID: 26634117; PMCID: PMC4667482.
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Functions and responsibilities of organizations dealing with surrogate motherhood in the UK.

Human fertility (Cambridge, England)

van Den Akker OB.
PMID: 11844301
Hum Fertil (Camb). 1998;1(1):10-13.

The separation of maternity from social motherhood and progress in reproductive technology raise many social, psychological, medical and legal issues (van den Akker, 1994). The most recent British Medical Association report (BMA, 1996) acknowledged the practice of surrogacy and...

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van Den Akker OB. Functions and responsibilities of organizations dealing with surrogate motherhood in the UK. Hum Fertil (Camb). 1998;1(1):10-13
van Den Akker, O. B. (1998). Functions and responsibilities of organizations dealing with surrogate motherhood in the UK. Human fertility (Cambridge, England), 1(1), 10-13.
van Den Akker, Olga B. A.. "Functions and responsibilities of organizations dealing with surrogate motherhood in the UK." Human fertility (Cambridge, England) vol. 1,1 (1998): 10-13.
van Den Akker OB. Functions and responsibilities of organizations dealing with surrogate motherhood in the UK. Hum Fertil (Camb). 1998;1(1):10-13. PMID: 11844301.
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Multimorbidity's many challenges.

BMJ (Clinical research ed.)

Fortin M, Soubhi H, Hudon C, Bayliss EA, van den Akker M.
PMID: 17510108
BMJ. 2007 May 19;334(7602):1016-7. doi: 10.1136/bmj.39201.463819.2C.

No abstract available.

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Fortin M, Soubhi H, Hudon C, et al. Multimorbidity's many challenges. BMJ. 2007;334(7602):1016-7doi: 10.1136/bmj.39201.463819.2C.
Fortin, M., Soubhi, H., Hudon, C., Bayliss, E. A., & van den Akker, M. (2007). Multimorbidity's many challenges. BMJ (Clinical research ed.), 334(7602), 1016-7. https://doi.org/10.1136/bmj.39201.463819.2C
Fortin, Martin, et al. "Multimorbidity's many challenges." BMJ (Clinical research ed.) vol. 334,7602 (2007): 1016-7. doi: https://doi.org/10.1136/bmj.39201.463819.2C
Fortin M, Soubhi H, Hudon C, Bayliss EA, van den Akker M. Multimorbidity's many challenges. BMJ. 2007 May 19;334(7602):1016-7. doi: 10.1136/bmj.39201.463819.2C. PMID: 17510108; PMCID: PMC1871747.
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Best pharmaceuticals for children: how far have we come?.

Current therapeutic research, clinical and experimental

Mazer-Amirshahi M, van den Anker J.
PMID: 25067983
Curr Ther Res Clin Exp. 2014 May 08;76:32-3. doi: 10.1016/j.curtheres.2013.05.001. eCollection 2014 Dec.

No abstract available.

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Mazer-Amirshahi M, van den Anker J. Best pharmaceuticals for children: how far have we come?. Curr Ther Res Clin Exp. 2014;76:32-3doi: 10.1016/j.curtheres.2013.05.001.
Mazer-Amirshahi, M., & van den Anker, J. (2014). Best pharmaceuticals for children: how far have we come?. Current therapeutic research, clinical and experimental, 7632-3. https://doi.org/10.1016/j.curtheres.2013.05.001
Mazer-Amirshahi, Maryann, and van den Anker, John. "Best pharmaceuticals for children: how far have we come?." Current therapeutic research, clinical and experimental vol. 76 (2014): 32-3. doi: https://doi.org/10.1016/j.curtheres.2013.05.001
Mazer-Amirshahi M, van den Anker J. Best pharmaceuticals for children: how far have we come?. Curr Ther Res Clin Exp. 2014 May 08;76:32-3. doi: 10.1016/j.curtheres.2013.05.001. eCollection 2014 Dec. PMID: 25067983; PMCID: PMC4008771.
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Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment.

International journal of endocrinology and metabolism

van der Kaay D, van den Akker E.
PMID: 25237318
Int J Endocrinol Metab. 2014 Jul 01;12(3):e14657. doi: 10.5812/ijem.14657. eCollection 2014 Jul.

INTRODUCTION: Nonclassical congenital adrenal hyperplasia (CAH) is characterized by sufficient cortisol and aldosterone production at the cost of androgen overproduction. Hydrocortisone or dexamethasone in supraphysiological doses are current treatment; however, their downside is suppression of endogenous cortisol production resulting...

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van der Kaay D, van den Akker E. Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment. Int J Endocrinol Metab. 2014;12(3):e14657doi: 10.5812/ijem.14657.
van der Kaay, D., & van den Akker, E. (2014). Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment. International journal of endocrinology and metabolism, 12(3), e14657. https://doi.org/10.5812/ijem.14657
van der Kaay, Danielle, and van den Akker, Erica. "Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment." International journal of endocrinology and metabolism vol. 12,3 (2014): e14657. doi: https://doi.org/10.5812/ijem.14657
van der Kaay D, van den Akker E. Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment. Int J Endocrinol Metab. 2014 Jul 01;12(3):e14657. doi: 10.5812/ijem.14657. eCollection 2014 Jul. PMID: 25237318; PMCID: PMC4166204.
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Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi.

International health

van den Akker T, Radge G, Mateyu A, Mwagomba B, Bemelmans M, Reid T.
PMID: 24038052
Int Health. 2011 Mar;3(1):66-8. doi: 10.1016/j.inhe.2010.11.001.

Attendance for intrapartum care in Thyolo District, Malawi, was studied following implementation of a locally valued, non-monetary incentive. The number of facility-based deliveries per month was compared between the fourth quarter of 2007 and the third quarter of 2009,...

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van den Akker T, Radge G, Mateyu A, et al. Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi. Int Health. 2011;3(1):66-8doi: 10.1016/j.inhe.2010.11.001.
van den Akker, T., Radge, G., Mateyu, A., Mwagomba, B., Bemelmans, M., & Reid, T. (2011). Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi. International health, 3(1), 66-8. https://doi.org/10.1016/j.inhe.2010.11.001
van den Akker, Thomas, et al. "Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi." International health vol. 3,1 (2011): 66-8. doi: https://doi.org/10.1016/j.inhe.2010.11.001
van den Akker T, Radge G, Mateyu A, Mwagomba B, Bemelmans M, Reid T. Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi. Int Health. 2011 Mar;3(1):66-8. doi: 10.1016/j.inhe.2010.11.001. PMID: 24038052.
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Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium.

Journal of comorbidity

van Merode T, van de Ven K, van den Akker M.
PMID: 29651408
J Comorb. 2018 Mar 08;8(1):9-15. doi: 10.15256/joc.2018.8.119. eCollection 2018.

BACKGROUND: Physicians and other healthcare professionals involved in the care of patients with multimorbidity should consider the problems these patients experience in managing their own conditions. However, treatment burden from the patient's perspective has been poorly explored, even though...

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van Merode T, van de Ven K, van den Akker M. Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium. J Comorb. 2018;8(1):9-15doi: 10.15256/joc.2018.8.119.
van Merode, T., van de Ven, K., & van den Akker, M. (2018). Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium. Journal of comorbidity, 8(1), 9-15. https://doi.org/10.15256/joc.2018.8.119
van Merode, Tiny, et al. "Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium." Journal of comorbidity vol. 8,1 (2018): 9-15. doi: https://doi.org/10.15256/joc.2018.8.119
van Merode T, van de Ven K, van den Akker M. Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium. J Comorb. 2018 Mar 08;8(1):9-15. doi: 10.15256/joc.2018.8.119. eCollection 2018. PMID: 29651408; PMCID: PMC5885066.
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Effects of a high-protein intake on metabolic targets for weight loss in children with obesity: a randomized trial.

Obesity science & practice

Veldhorst MAB, Verbruggen SCAT, van Harskamp D, Vermes A, Schierbeek H, van Goudoever JB, van den Akker ELT.
PMID: 30151229
Obes Sci Pract. 2018 May 24;4(4):347-356. doi: 10.1002/osp4.277. eCollection 2018 Aug.

OBJECTIVE: The objective of this research is to study effects of a 4-week high-protein (HP) diet on energy intake, resting energy expenditure (REE), protein turnover and body composition in children with obesity.METHODS: In this randomized placebo-controlled single-blind crossover study,...

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Veldhorst MAB, Verbruggen SCAT, van Harskamp D, et al. Effects of a high-protein intake on metabolic targets for weight loss in children with obesity: a randomized trial. Obes Sci Pract. 2018;4(4):347-356doi: 10.1002/osp4.277.
Veldhorst, M. A. B., Verbruggen, S. C. A. T., van Harskamp, D., Vermes, A., Schierbeek, H., van Goudoever, J. B., & van den Akker, E. L. T. (2018). Effects of a high-protein intake on metabolic targets for weight loss in children with obesity: a randomized trial. Obesity science & practice, 4(4), 347-356. https://doi.org/10.1002/osp4.277
Veldhorst, M A B, et al. "Effects of a high-protein intake on metabolic targets for weight loss in children with obesity: a randomized trial." Obesity science & practice vol. 4,4 (2018): 347-356. doi: https://doi.org/10.1002/osp4.277
Veldhorst MAB, Verbruggen SCAT, van Harskamp D, Vermes A, Schierbeek H, van Goudoever JB, van den Akker ELT. Effects of a high-protein intake on metabolic targets for weight loss in children with obesity: a randomized trial. Obes Sci Pract. 2018 May 24;4(4):347-356. doi: 10.1002/osp4.277. eCollection 2018 Aug. PMID: 30151229; PMCID: PMC6105699.
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Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis.

Surgery journal (New York, N.Y.)

Huizing E, Vos CG, Hulsebos RG, van den Akker PJ, Borst GJ, Ünlü Ç.
PMID: 29915809
Surg J (N Y). 2018 Jun 15;4(2):e96-e101. doi: 10.1055/s-0038-1655757. eCollection 2018 Apr.

No abstract available.

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Huizing E, Vos CG, Hulsebos RG, et al. Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis. Surg J (N Y). 2018;4(2):e96-e101doi: 10.1055/s-0038-1655757.
Huizing, E., Vos, C. G., Hulsebos, R. G., van den Akker, P. J., Borst, G. J., & Ünlü, �. �. (2018). Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis. Surgery journal (New York, N.Y.), 4(2), e96-e101. https://doi.org/10.1055/s-0038-1655757
Huizing, Eline, et al. "Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis." Surgery journal (New York, N.Y.) vol. 4,2 (2018): e96-e101. doi: https://doi.org/10.1055/s-0038-1655757
Huizing E, Vos CG, Hulsebos RG, van den Akker PJ, Borst GJ, Ünlü Ç. Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis. Surg J (N Y). 2018 Jun 15;4(2):e96-e101. doi: 10.1055/s-0038-1655757. eCollection 2018 Apr. PMID: 29915809; PMCID: PMC6003887.
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Showing 1 to 12 of 194 entries