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Showing 1 to 12 of 91 entries
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Dynamic changes of five neurotransmitters and their related enzymes in various rat tissues following β-asarone and levodopa co-administration.

Experimental and therapeutic medicine

Huang L, Deng M, Fang Y, Li L.
PMID: 26622527
Exp Ther Med. 2015 Oct;10(4):1566-1572. doi: 10.3892/etm.2015.2704. Epub 2015 Aug 24.

The aim of the present study was to investigate the dynamic changes of five neurotransmitters and their associated enzymes in the rat plasma and brain tissues following the co-administration of β-asarone and levodopa (L-dopa). The rats were divided into...

Motor Function in MPTP-Treated Tree Shrews (Tupaia belangeri chinensis).

Neurochemical research

Ma KL, Gao JH, Huang ZQ, Zhang Y, Kuang DX, Jiang QF, Han YY, Li C, Wang WG, Huang XY, Xu J, Tong PF, Yin XX, Dai JJ.
PMID: 23797325
Neurochem Res. 2013 Jun 25; doi: 10.1007/s11064-013-1099-8. Epub 2013 Jun 25.

The tree shrew, a new experimental animal model, has been used to study a variety of diseases, especially diseases of the nervous system. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is the gold standard for toxin-based animal models of Parkinson's disease (PD) because MPTP...

Evidence that 5-HT(2) Antagonism Elicits a 5-HT(3)-Mediated Increase in Dopamine Transmission.

Journal of biomedical science

Wu WH, Huang NK, Tseng CJ, Yin TH, Tung CS.
PMID: 11725054
J Biomed Sci. 1995 Apr;2(2):174-182. doi: 10.1007/BF02253069.

Amperozide, a novel atypical antipsychotic drug with few extrapyramidal side effects, is a strong serotonin(2) (5-HT(2)) antagonist but has low affinity for dopamine receptors in vitro. The effect of amperozide on the dopaminergic synapse was studied with an in...

Acute exposure to organochlorine pesticides does not affect striatal dopamine in mice.

Neurotoxicity research

Thiffault C, Langston WJ, Di Monte DA.
PMID: 15111243
Neurotox Res. 2001 Nov;3(6):537-43. doi: 10.1007/BF03033209.

The purpose of this study was to evaluate the possible association between the risk of developing Parkinson's disease (PD) and exposure to organochlorine pesticides in the mouse model. Animals were treated with a single subcutaneous injection of either dieldrin...

Potentiometric studies on the complexation of copper(II) by phenolic acids as discrete ligand models of humic substances.

Talanta

Borges F, Guimarães C, Lima JL, Pinto I, Reis S.
PMID: 18970037
Talanta. 2005 Apr 30;66(3):670-3. doi: 10.1016/j.talanta.2004.12.012. Epub 2005 Jan 18.

Studies on the complexation of copper(II) by phenolic acids, as ligand models of humic substances were done by potentiometry. The acids under study were: 3,4-dihydroxyhydrocinnamic acid or hydrocaffeic acid (1), 3,4-dihydroxyphenylacetic acid (2) and 3,4-dihydroxybenzoic acid or protocatechuic acid...

Study of the tautomeric forms of 3,4-dihydroxyphenylacetic acid by carbon-13 nuclear magnetic resonance spectroscopy.

Talanta

Ishimitsu T, Fujiwara Y, Hirose S.
PMID: 18962380
Talanta. 1979 Jan;26(1):67-9. doi: 10.1016/0039-9140(79)80160-5.

The pH-dependent (13)C chemical shifts indicate an approximately 1:1 ratio of the 3-OH:4-OH tautomeric forms of singly dissociated 3,4-dihydroxyphenylacetic acid. It is found that the (13)C chemical-shift method is an effective technique for determining tautomeric forms from pK values.

Determination of isatin and monoamine neurotransmitters in rat brain with liquid chromatography using palladium hexacyanoferrate modified electrode.

Analytica chimica acta

Xu H, Wang D, Zhang W, Zhu W, Yamamoto K, Jin L.
PMID: 17723673
Anal Chim Acta. 2006 Sep 08;577(2):207-13. doi: 10.1016/j.aca.2006.06.042. Epub 2006 Jun 27.

The fabrication and application of a novel electrochemical detector (ED) with palladium hexacyanoferrate (PdHCF) chemically modified electrode (CME) for liquid chromatography (LC) were described. The electrochemical behaviors of isatin, monoamine neurotransmitters and their metabolites at this CME were investigated...

Tyrosine hydroxylase activity and dopamine turnover of rainbow trout (Oncorhynchus mykiss) brain: the special status of the hypothalamus.

Fish physiology and biochemistry

Linard B, Bennani S, Jego P, Saligaut C.
PMID: 24193987
Fish Physiol Biochem. 1996 Feb;15(1):41-8. doi: 10.1007/BF01874836.

The dynamics of catecholamine (CA)-synthesis enzymes have been poorly studied in fish. Tyrosine hydroxylase (TH), the rate-limiting enzyme of CA synthesis has been only studied inin vitro conditions. In the present report thein vivo CA synthesis and the CA...

Pilose Antler Extracts (PAEs) Protect against Neurodegeneration in 6-OHDA-Induced Parkinson's Disease Rat Models.

Evidence-based complementary and alternative medicine : eCAM

Li C, Sun Y, Yang W, Ma S, Zhang L, Zhao J, Zhao X, Wang Y.
PMID: 30728849
Evid Based Complement Alternat Med. 2019 Jan 08;2019:7276407. doi: 10.1155/2019/7276407. eCollection 2019.

Parkinson's disease (PD) is one of the most common neurodegenerative diseases worldwide. Although dopamine replacement therapy mitigates motor dysfunction in PD patients, there are no therapeutics that are currently available to reverse neuronal cell death in the substantia nigra...

Silica stationary phase-based on-line sample enrichment coupled with LC-MS/MS for the quantification of dopamine, serotonin and their metabolites in rat brain microdialysates.

Analytica chimica acta

Kim M, Lee JG, Yang CH, Lee S.
PMID: 27155302
Anal Chim Acta. 2016 Jun 07;923:55-65. doi: 10.1016/j.aca.2016.03.021. Epub 2016 Mar 23.

Accurate measurement of trace levels of endogenous compounds remains challenging despite advancements in analytical technologies. In particular, monoamine neurotransmitters such as dopamine (DA) and serotonin (5-HT) are polar compounds with low molecular weights, which complicates the optimization of retention...

The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model.

PloS one

Ahring KK, Dagnæs-Hansen F, Brüel A, Christensen M, Jensen E, Jensen TG, Johannsen M, Johansen KS, Lund AM, Madsen JG, Brøndum-Nielsen K, Pedersen M, Sørensen LK, Kjolby M, Møller LB.
PMID: 35015767
PLoS One. 2022 Jan 11;17(1):e0261150. doi: 10.1371/journal.pone.0261150. eCollection 2022.

INTRODUCTION: Management of phenylketonuria (PKU) is mainly achieved through dietary control with limited intake of phenylalanine (Phe) from food, supplemented with low protein (LP) food and a mixture of free synthetic (FS) amino acids (AA) (FSAA). Casein glycomacropeptide (CGMP)...

Polymer Modified Carbon Fiber-Microelectrodes and Waveform Modifications Enhance Neurotransmitter Metabolite Detection.

Analytical methods : advancing methods and applications

Raju D, Mendoza A, Wonnenberg P, Mohanaraj S, Sarbanes M, Truong C, Zestos AG.
PMID: 34079589
Anal Methods. 2019 Mar 28;11(12):1620-1630. doi: 10.1039/c8ay02737d. Epub 2019 Feb 19.

Carbon-fiber microelectrodes (CFMEs) have been used for several years for the detection of neurotransmitters such as dopamine. Dopamine is a fundamentally important neurotransmitter and is also metabolized at a subsecond timescale. Recently, several metabolites of dopamine have been shown...

Showing 1 to 12 of 91 entries