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Showing 1 to 12 of 237 entries
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Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto.

Frontiers in pharmacology

Kono T, Shimada M, Yamamoto M, Kaneko A, Oomiya Y, Kubota K, Kase Y, Lee K, Uezono Y.
PMID: 26300774
Front Pharmacol. 2015 Aug 04;6:159. doi: 10.3389/fphar.2015.00159. eCollection 2015.

Herbal medicines have been used in Japan for more than 1500 years and traditional Japanese medicines (Kampo medicines) are now fully integrated into the modern healthcare system. In total, 148 Kampo formulae are officially approved as prescription drugs and...

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Kono T, Shimada M, Yamamoto M, et al. Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto. Front Pharmacol. 2015;6:159doi: 10.3389/fphar.2015.00159.
Kono, T., Shimada, M., Yamamoto, M., Kaneko, A., Oomiya, Y., Kubota, K., Kase, Y., Lee, K., & Uezono, Y. (2015). Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto. Frontiers in pharmacology, 6159. https://doi.org/10.3389/fphar.2015.00159
Kono, Toru, et al. "Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto." Frontiers in pharmacology vol. 6 (2015): 159. doi: https://doi.org/10.3389/fphar.2015.00159
Kono T, Shimada M, Yamamoto M, Kaneko A, Oomiya Y, Kubota K, Kase Y, Lee K, Uezono Y. Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto. Front Pharmacol. 2015 Aug 04;6:159. doi: 10.3389/fphar.2015.00159. eCollection 2015. PMID: 26300774; PMCID: PMC4523940.
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Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection.

Drug target insights

Ohlsson B, Melander O.
PMID: 26244009
Drug Target Insights. 2015 Jul 13;9:21-7. doi: 10.4137/DTI.S26589. eCollection 2015.

Evidence of interactions between the enteric nervous system, neuropeptides, and the immune system is growing. The aim of this study was to examine basal plasma levels of a variety of peptide precursors in patients with inflammatory bowel disease (IBD)....

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Ohlsson B, Melander O. Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection. Drug Target Insights. 2015;9:21-7doi: 10.4137/DTI.S26589.
Ohlsson, B., & Melander, O. (2015). Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection. Drug target insights, 921-7. https://doi.org/10.4137/DTI.S26589
Ohlsson, Bodil, and Melander, Olle. "Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection." Drug target insights vol. 9 (2015): 21-7. doi: https://doi.org/10.4137/DTI.S26589
Ohlsson B, Melander O. Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection. Drug Target Insights. 2015 Jul 13;9:21-7. doi: 10.4137/DTI.S26589. eCollection 2015. PMID: 26244009; PMCID: PMC4501700.
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Plasma concentrations of adrenomedullin and atrial and brain natriuretic peptides in patients with adrenal pheochromocytoma.

Oncology letters

Hu W, Shi L, Zhou PH, Zhang XB.
PMID: 26722306
Oncol Lett. 2015 Nov;10(5):3163-3170. doi: 10.3892/ol.2015.3660. Epub 2015 Sep 02.

The present study aimed to evaluate any changes in the plasma concentrations of adrenomedullin (ADM), atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in patients with adrenal pheochromocytoma (PC). The plasma concentrations of the three peptides were measured...

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Hu W, Shi L, Zhou PH, et al. Plasma concentrations of adrenomedullin and atrial and brain natriuretic peptides in patients with adrenal pheochromocytoma. Oncol Lett. 2015;10(5):3163-3170doi: 10.3892/ol.2015.3660.
Hu, W., Shi, L., Zhou, P. H., & Zhang, X. B. (2015). Plasma concentrations of adrenomedullin and atrial and brain natriuretic peptides in patients with adrenal pheochromocytoma. Oncology letters, 10(5), 3163-3170. https://doi.org/10.3892/ol.2015.3660
Hu, Wei, et al. "Plasma concentrations of adrenomedullin and atrial and brain natriuretic peptides in patients with adrenal pheochromocytoma." Oncology letters vol. 10,5 (2015): 3163-3170. doi: https://doi.org/10.3892/ol.2015.3660
Hu W, Shi L, Zhou PH, Zhang XB. Plasma concentrations of adrenomedullin and atrial and brain natriuretic peptides in patients with adrenal pheochromocytoma. Oncol Lett. 2015 Nov;10(5):3163-3170. doi: 10.3892/ol.2015.3660. Epub 2015 Sep 02. PMID: 26722306; PMCID: PMC4665925.
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Effect of nucleoprotein factor-kB (NF-κB) in endothelial cells during high blood flow-associated pulmonary vascular remodeling on vasoactive substances adrenomedullin and prostacyclin.

International journal of clinical and experimental medicine

Yang J, Wang W, Dong M, Yu X, Luo Q.
PMID: 26550335
Int J Clin Exp Med. 2015 Aug 15;8(8):13842-7. eCollection 2015.

The aim of this study was to investigate the role of nucleoprotein factor-kB (NF-κB) on the production and secretion of vasoactive substances adrenomedullin (ADM) and prostacyclin (PGI2) by endothelial cells in a high blood flow, pulmonary hypertension in vivo...

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Yang J, Wang W, Dong M, et al. Effect of nucleoprotein factor-kB (NF-κB) in endothelial cells during high blood flow-associated pulmonary vascular remodeling on vasoactive substances adrenomedullin and prostacyclin. Int J Clin Exp Med. 2015;8(8):13842-7
Yang, J., Wang, W., Dong, M., Yu, X., & Luo, Q. (2015). Effect of nucleoprotein factor-kB (NF-κB) in endothelial cells during high blood flow-associated pulmonary vascular remodeling on vasoactive substances adrenomedullin and prostacyclin. International journal of clinical and experimental medicine, 8(8), 13842-7.
Yang, Jie, et al. "Effect of nucleoprotein factor-kB (NF-κB) in endothelial cells during high blood flow-associated pulmonary vascular remodeling on vasoactive substances adrenomedullin and prostacyclin." International journal of clinical and experimental medicine vol. 8,8 (2015): 13842-7.
Yang J, Wang W, Dong M, Yu X, Luo Q. Effect of nucleoprotein factor-kB (NF-κB) in endothelial cells during high blood flow-associated pulmonary vascular remodeling on vasoactive substances adrenomedullin and prostacyclin. Int J Clin Exp Med. 2015 Aug 15;8(8):13842-7. eCollection 2015. PMID: 26550335; PMCID: PMC4613020.
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Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study.

Annals of intensive care

Póvoa P, Martin-Loeches I, Ramirez P, Bos LD, Esperatti M, Silvestre J, Gili G, Goma G, Berlanga E, Espasa M, Gonçalves E, Torres A, Artigas A.
PMID: 27076187
Ann Intensive Care. 2016 Dec;6(1):32. doi: 10.1186/s13613-016-0134-8. Epub 2016 Apr 14.

BACKGROUND: Prediction of diagnosis of ventilator-associated pneumonia (VAP) remains difficult. Our aim was to assess the value of biomarker kinetics in VAP prediction.METHODS: We performed a prospective, multicenter, observational study to evaluate predictive accuracy of biomarker kinetics, namely C-reactive...

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Póvoa P, Martin-Loeches I, Ramirez P, et al. Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study. Ann Intensive Care. 2016;6(1):32doi: 10.1186/s13613-016-0134-8.
Póvoa, P., Martin-Loeches, I., Ramirez, P., Bos, L. D., Esperatti, M., Silvestre, J., Gili, G., Goma, G., Berlanga, E., Espasa, M., Gonçalves, E., Torres, A., & Artigas, A. (2016). Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study. Annals of intensive care, 6(1), 32. https://doi.org/10.1186/s13613-016-0134-8
Póvoa, Pedro, et al. "Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study." Annals of intensive care vol. 6,1 (2016): 32. doi: https://doi.org/10.1186/s13613-016-0134-8
Póvoa P, Martin-Loeches I, Ramirez P, Bos LD, Esperatti M, Silvestre J, Gili G, Goma G, Berlanga E, Espasa M, Gonçalves E, Torres A, Artigas A. Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study. Ann Intensive Care. 2016 Dec;6(1):32. doi: 10.1186/s13613-016-0134-8. Epub 2016 Apr 14. PMID: 27076187; PMCID: PMC4830786.
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Adrenomedullin, periodontitis, diabetes-unraveling the equivocal relationship: A clinicobiochemical cross-sectional study.

Contemporary clinical dentistry

Suchetha A, Garg A, Lakshmi P, Bhat D, Sapna N, Apoorva SM.
PMID: 24403788
Contemp Clin Dent. 2013 Oct;4(4):454-9. doi: 10.4103/0976-237X.123040.

CONTEXT: Antimicrobial proteins and peptides constitute a diverse class of host-defense molecules that act early to combat invasion and infection with bacteria and other microorganisms. Among the various antimicrobial peptides in the oral cavity, adrenomedullin (ADM), a cationic peptide,...

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Suchetha A, Garg A, Lakshmi P, et al. Adrenomedullin, periodontitis, diabetes-unraveling the equivocal relationship: A clinicobiochemical cross-sectional study. Contemp Clin Dent. 2013;4(4):454-9doi: 10.4103/0976-237X.123040.
Suchetha, A., Garg, A., Lakshmi, P., Bhat, D., Sapna, N., & Apoorva, S. M. (2013). Adrenomedullin, periodontitis, diabetes-unraveling the equivocal relationship: A clinicobiochemical cross-sectional study. Contemporary clinical dentistry, 4(4), 454-9. https://doi.org/10.4103/0976-237X.123040
Suchetha, A, et al. "Adrenomedullin, periodontitis, diabetes-unraveling the equivocal relationship: A clinicobiochemical cross-sectional study." Contemporary clinical dentistry vol. 4,4 (2013): 454-9. doi: https://doi.org/10.4103/0976-237X.123040
Suchetha A, Garg A, Lakshmi P, Bhat D, Sapna N, Apoorva SM. Adrenomedullin, periodontitis, diabetes-unraveling the equivocal relationship: A clinicobiochemical cross-sectional study. Contemp Clin Dent. 2013 Oct;4(4):454-9. doi: 10.4103/0976-237X.123040. PMID: 24403788; PMCID: PMC3883323.
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Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

Li W, Kong QY, Zhao CF, Zhao F, Li FH, Xia W, Wang R, Hu YM, Hua M.
PMID: 24345914
Braz J Med Biol Res. 2013 Dec;46(12):1047-1055. doi: 10.1590/1414-431X20132882. Epub 2013 Dec 10.

To understand the pathophysiological mechanisms of pulmonary arterial smooth muscle cell (PASMC) proliferation and extracellular-matrix accumulation in the development of pulmonary hypertension and remodeling, this study determined the effects of different doses of adrenomedullin (ADM) and adrenotensin (ADT) on...

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Li W, Kong QY, Zhao CF, et al. Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells. Braz J Med Biol Res. 2013;46(12):1047-1055doi: 10.1590/1414-431X20132882.
Li, W., Kong, Q. Y., Zhao, C. F., Zhao, F., Li, F. H., Xia, W., Wang, R., Hu, Y. M., & Hua, M. (2013). Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 46(12), 1047-1055. https://doi.org/10.1590/1414-431X20132882
Li, W, et al. "Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells." Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas vol. 46,12 (2013): 1047-1055. doi: https://doi.org/10.1590/1414-431X20132882
Li W, Kong QY, Zhao CF, Zhao F, Li FH, Xia W, Wang R, Hu YM, Hua M. Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells. Braz J Med Biol Res. 2013 Dec;46(12):1047-1055. doi: 10.1590/1414-431X20132882. Epub 2013 Dec 10. PMID: 24345914; PMCID: PMC3935277.
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Expression and clinical significance of focal adhesion kinase and adrenomedullin in epithelial ovarian cancer.

Oncology letters

Li M, Hong LI, Liao M, Guo G.
PMID: 26622614
Oncol Lett. 2015 Aug;10(2):1003-1007. doi: 10.3892/ol.2015.3278. Epub 2015 May 27.

The aim of the present study was to investigate the expression of focal adhesion kinase (FAK) and adrenomedullin (ADM) and determine their clinical significance and cooperative role in human epithelial ovarian cancer. The expression of FAK and ADM was...

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Li M, Hong LI, Liao M, et al. Expression and clinical significance of focal adhesion kinase and adrenomedullin in epithelial ovarian cancer. Oncol Lett. 2015;10(2):1003-1007doi: 10.3892/ol.2015.3278.
Li, M., Hong, L. I., Liao, M., & Guo, G. (2015). Expression and clinical significance of focal adhesion kinase and adrenomedullin in epithelial ovarian cancer. Oncology letters, 10(2), 1003-1007. https://doi.org/10.3892/ol.2015.3278
Li, Mingqun, et al. "Expression and clinical significance of focal adhesion kinase and adrenomedullin in epithelial ovarian cancer." Oncology letters vol. 10,2 (2015): 1003-1007. doi: https://doi.org/10.3892/ol.2015.3278
Li M, Hong LI, Liao M, Guo G. Expression and clinical significance of focal adhesion kinase and adrenomedullin in epithelial ovarian cancer. Oncol Lett. 2015 Aug;10(2):1003-1007. doi: 10.3892/ol.2015.3278. Epub 2015 May 27. PMID: 26622614; PMCID: PMC4508992.
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Biomarkers Beyond the Natriuretic Peptides for Chronic Heart Failure: Galectin-3 and Soluble ST2.

EJIFCC

Wu AH.
PMID: 27683422
EJIFCC. 2012 Oct 12;23(3):98-102. eCollection 2012 Oct.

B-type natriuretic peptide (BNP) and NT-proBNP are widely used plasma biomarkers for the diagnosis of acute decompensated heart failure and prognosis for future cardiac disease. The clinical performance of these tests for management of chronic heart failure is somewhat...

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Wu AH. Biomarkers Beyond the Natriuretic Peptides for Chronic Heart Failure: Galectin-3 and Soluble ST2. EJIFCC. 2012;23(3):98-102
Wu, A. H. (2012). Biomarkers Beyond the Natriuretic Peptides for Chronic Heart Failure: Galectin-3 and Soluble ST2. EJIFCC, 23(3), 98-102.
Wu, Alan H B. "Biomarkers Beyond the Natriuretic Peptides for Chronic Heart Failure: Galectin-3 and Soluble ST2." EJIFCC vol. 23,3 (2012): 98-102.
Wu AH. Biomarkers Beyond the Natriuretic Peptides for Chronic Heart Failure: Galectin-3 and Soluble ST2. EJIFCC. 2012 Oct 12;23(3):98-102. eCollection 2012 Oct. PMID: 27683422; PMCID: PMC4975258.
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Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition.

Frontiers in physiology

Martínez-Herrero S, Larrayoz IM, Ochoa-Callejero L, Fernández LJ, Allueva A, Ochoa I, Martínez A.
PMID: 27445864
Front Physiol. 2016 Jun 30;7:280. doi: 10.3389/fphys.2016.00280. eCollection 2016.

Despite recent advances in the understanding and treatment options for osteoporosis, this condition remains a serious public health issue. Adrenomedullin (AM) is a regulatory peptide with reported activity on bone remodeling. To better understand this relationship we built an...

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Martínez-Herrero S, Larrayoz IM, Ochoa-Callejero L, et al. Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition. Front Physiol. 2016;7:280doi: 10.3389/fphys.2016.00280.
Martínez-Herrero, S., Larrayoz, I. M., Ochoa-Callejero, L., Fernández, L. J., Allueva, A., Ochoa, I., & Martínez, A. (2016). Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition. Frontiers in physiology, 7280. https://doi.org/10.3389/fphys.2016.00280
Martínez-Herrero, Sonia, et al. "Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition." Frontiers in physiology vol. 7 (2016): 280. doi: https://doi.org/10.3389/fphys.2016.00280
Martínez-Herrero S, Larrayoz IM, Ochoa-Callejero L, Fernández LJ, Allueva A, Ochoa I, Martínez A. Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition. Front Physiol. 2016 Jun 30;7:280. doi: 10.3389/fphys.2016.00280. eCollection 2016. PMID: 27445864; PMCID: PMC4928306.
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Nociceptin Has Vasodilator Activity in the Pulmonary Vascular Bed of the Rat.

Journal of cardiovascular pharmacology and therapeutics

Nossaman BD, Champion HC, Kaye AD, Anwar M, Feng CJ, Kadowitz PJ.
PMID: 10684506
J Cardiovasc Pharmacol Ther. 1998 Jul;3(3):253-258. doi: 10.1177/107424849800300309.

BACKGROUND: Recent studies have shown that the newly discovered endogenous opioid-like peptide, nociceptin, has vasodilator activity in the peripheral vascular bed. However, little if anything is known about the effects of the peptide in the pulmonary vascular bed. Therefore,...

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Nossaman BD, Champion HC, Kaye AD, et al. Nociceptin Has Vasodilator Activity in the Pulmonary Vascular Bed of the Rat. J Cardiovasc Pharmacol Ther. 1998;3(3):253-258doi: 10.1177/107424849800300309.
Nossaman, B. D., Champion, H. C., Kaye, A. D., Anwar, M., Feng, C. J., & Kadowitz, P. J. (1998). Nociceptin Has Vasodilator Activity in the Pulmonary Vascular Bed of the Rat. Journal of cardiovascular pharmacology and therapeutics, 3(3), 253-258. https://doi.org/10.1177/107424849800300309
Nossaman, et al. "Nociceptin Has Vasodilator Activity in the Pulmonary Vascular Bed of the Rat." Journal of cardiovascular pharmacology and therapeutics vol. 3,3 (1998): 253-258. doi: https://doi.org/10.1177/107424849800300309
Nossaman BD, Champion HC, Kaye AD, Anwar M, Feng CJ, Kadowitz PJ. Nociceptin Has Vasodilator Activity in the Pulmonary Vascular Bed of the Rat. J Cardiovasc Pharmacol Ther. 1998 Jul;3(3):253-258. doi: 10.1177/107424849800300309. PMID: 10684506.
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Gene therapy for hypertension: a review of potential targets.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Chao J, Wang C, Chao L.
PMID: 18031114
BioDrugs. 1999 Jan;11(1):43-53. doi: 10.2165/00063030-199911010-00005.

Somatic gene delivery approaches have received wide attention as a new technique for studying gene expression and as a potential therapeutic tool in treating both inherited and acquired diseases. Recent studies using nonviral and viral vectors have shown great...

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Chao J, Wang C, Chao L. Gene therapy for hypertension: a review of potential targets. BioDrugs. 1999;11(1):43-53doi: 10.2165/00063030-199911010-00005.
Chao, J., Wang, C., & Chao, L. (1999). Gene therapy for hypertension: a review of potential targets. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 11(1), 43-53. https://doi.org/10.2165/00063030-199911010-00005
Chao, J, et al. "Gene therapy for hypertension: a review of potential targets." BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy vol. 11,1 (1999): 43-53. doi: https://doi.org/10.2165/00063030-199911010-00005
Chao J, Wang C, Chao L. Gene therapy for hypertension: a review of potential targets. BioDrugs. 1999 Jan;11(1):43-53. doi: 10.2165/00063030-199911010-00005. PMID: 18031114.
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Showing 1 to 12 of 237 entries