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Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents

STEM and boys

Masliukaite I.
GSID: gf7fdJYQS_MJ
M Poganitsch-Korhonen, I Masliukaite, M Nurmio… - Leukemia, 2017 - nature.com

… before gonadotoxic treatment, prepubertal boys do not yet produce spermatozoa. … boys are cryopreservation of testicular tissue followed by autotransplantation of spermatogonial stem …

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Poganitsch-Korhonen, M., Masliukaite, I., Nurmio, M., Lähteenmäki, P., Van Wely, M., Van Pelt, A. M. M., ... & Stukenborg, J. B. (2017). Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents. Leukemia, 31(6), 1460-1463.
Poganitsch-Korhonen, M., et al. "Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents." Leukemia 31.6 (2017): 1460-1463.
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Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster.

Genetics and molecular biology

Jacociunas LV, Dihl RR, Lehmann M, de Barros Falcão Ferraz A, Richter MF, da Silva J, de Andrade HH.
PMID: 24688296
Genet Mol Biol. 2014 Mar;37(1):90-104. doi: 10.1590/s1415-47572014000100015. Epub 2013 Feb 28.

The genotoxicity of bloom head (BHE) and leaf (LE) extracts from artichoke (Cynara scolymus L.), and their ability to modulate the mutagenicity and recombinogenicity of two alkylating agents (ethyl methanesulfonate - EMS and mitomycin C - MMC) and the...

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Jacociunas LV, Dihl RR, Lehmann M, et al. Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster. Genet Mol Biol. 2013;37(1):90-104doi: 10.1590/s1415-47572014000100015.
Jacociunas, L. V., Dihl, R. R., Lehmann, M., de Barros Falcão Ferraz, A., Richter, M. F., da Silva, J., & de Andrade, H. H. (2014). Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster. Genetics and molecular biology, 37(1), 90-104. https://doi.org/10.1590/s1415-47572014000100015
Jacociunas, Laura Vicedo, et al. "Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster." Genetics and molecular biology vol. 37,1 (2014): 90-104. doi: https://doi.org/10.1590/s1415-47572014000100015
Jacociunas LV, Dihl RR, Lehmann M, de Barros Falcão Ferraz A, Richter MF, da Silva J, de Andrade HH. Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster. Genet Mol Biol. 2014 Mar;37(1):90-104. doi: 10.1590/s1415-47572014000100015. Epub 2013 Feb 28. PMID: 24688296; PMCID: PMC3958332.
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Profile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia.

OncoTargets and therapy

Hill BT, Kalaycio M.
PMID: 26366093
Onco Targets Ther. 2015 Aug 31;8:2391-7. doi: 10.2147/OTT.S68770. eCollection 2015.

Chronic lymphocytic leukemia (CLL) is a hematologic malignancy derived from a clonal population of mature B-lymphocytes characterized by relatively low CD20 antigen expression. Although the disease often takes an indolent course, the majority of patients will eventually require therapy....

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Hill BT, Kalaycio M. Profile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia. Onco Targets Ther. 2015;8:2391-7doi: 10.2147/OTT.S68770.
Hill, B. T., & Kalaycio, M. (2015). Profile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia. OncoTargets and therapy, 82391-7. https://doi.org/10.2147/OTT.S68770
Hill, Brian T, and Kalaycio, Matt. "Profile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia." OncoTargets and therapy vol. 8 (2015): 2391-7. doi: https://doi.org/10.2147/OTT.S68770
Hill BT, Kalaycio M. Profile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia. Onco Targets Ther. 2015 Aug 31;8:2391-7. doi: 10.2147/OTT.S68770. eCollection 2015. PMID: 26366093; PMCID: PMC4562745.
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Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer.

Case reports in oncology

Hashimoto A, Takada K, Horiguchi H, Sato T, Iyama S, Murase K, Kamihara Y, Ono K, Tatekoshi A, Hayashi T, Miyanishi K, Sato Y, Furuhata T, Kobune M, Takimoto R, Hirata K, Kato J.
PMID: 24932174
Case Rep Oncol. 2014 May 17;7(2):316-22. doi: 10.1159/000363100. eCollection 2014 May.

Therapy-related leukemia (TRL) has been reported to occur after treatment with alkylating agents and/or topoisomerase II inhibitors. Oxaliplatin (OXP) is used as a key drug for the treatment of colorectal cancer (CRC). Cisplatin and carboplatin have been linked with...

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Hashimoto A, Takada K, Horiguchi H, et al. Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer. Case Rep Oncol. 2014;7(2):316-22doi: 10.1159/000363100.
Hashimoto, A., Takada, K., Horiguchi, H., Sato, T., Iyama, S., Murase, K., Kamihara, Y., Ono, K., Tatekoshi, A., Hayashi, T., Miyanishi, K., Sato, Y., Furuhata, T., Kobune, M., Takimoto, R., Hirata, K., & Kato, J. (2014). Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer. Case reports in oncology, 7(2), 316-22. https://doi.org/10.1159/000363100
Hashimoto, Akari, et al. "Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer." Case reports in oncology vol. 7,2 (2014): 316-22. doi: https://doi.org/10.1159/000363100
Hashimoto A, Takada K, Horiguchi H, Sato T, Iyama S, Murase K, Kamihara Y, Ono K, Tatekoshi A, Hayashi T, Miyanishi K, Sato Y, Furuhata T, Kobune M, Takimoto R, Hirata K, Kato J. Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer. Case Rep Oncol. 2014 May 17;7(2):316-22. doi: 10.1159/000363100. eCollection 2014 May. PMID: 24932174; PMCID: PMC4049016.
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Shape-Selective Catalysis in the Alkylation of Naphthalene: Steric Interaction with the Nanospace of Zeolites.

Journal of nanoscience and nanotechnology

Sugi Y, Vinu A.
PMID: 26682357
J Nanosci Nanotechnol. 2015 Dec;15(12):9369-81. doi: 10.1166/jnn.2015.11586.

Steric interaction of reagents with nanospace of zeolites was studied in alkylation: isopropylation, sec-butylation, and tert-butylation of naphthalene (NP) over several large-pore zeolites to elucidate the mechanism of shape-selective catalysis. Selectivities for β,β- and 2,6-dialkylnaphthalene (DAN) were influenced by...

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Sugi Y, Vinu A. Shape-Selective Catalysis in the Alkylation of Naphthalene: Steric Interaction with the Nanospace of Zeolites. J Nanosci Nanotechnol. 2015;15(12):9369-81doi: 10.1166/jnn.2015.11586.
Sugi, Y., & Vinu, A. (2015). Shape-Selective Catalysis in the Alkylation of Naphthalene: Steric Interaction with the Nanospace of Zeolites. Journal of nanoscience and nanotechnology, 15(12), 9369-81. https://doi.org/10.1166/jnn.2015.11586
Sugi, Yoshihiro, and Vinu, Ajayan. "Shape-Selective Catalysis in the Alkylation of Naphthalene: Steric Interaction with the Nanospace of Zeolites." Journal of nanoscience and nanotechnology vol. 15,12 (2015): 9369-81. doi: https://doi.org/10.1166/jnn.2015.11586
Sugi Y, Vinu A. Shape-Selective Catalysis in the Alkylation of Naphthalene: Steric Interaction with the Nanospace of Zeolites. J Nanosci Nanotechnol. 2015 Dec;15(12):9369-81. doi: 10.1166/jnn.2015.11586. PMID: 26682357.
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Inducible Protective Processes in Animal Systems XIII: Comparative Analysis of Induction of Adaptive Response by EMS and MMS in Ehrlich Ascites Carcinoma Cells.

Scientifica

Mahadimane PV, Vasudev V.
PMID: 24999435
Scientifica (Cairo). 2014;2014:703136. doi: 10.1155/2014/703136. Epub 2014 Jun 04.

In order to investigate the presence of adaptive response in cancerous cells, two monofunctional alkylating agents, namely, ethyl methanesulfonate (EMS) and methyl methanesulfonate (MMS), were employed to treat Ehrlich ascites carcinoma (EAC) cells in vivo. Conditioning dose of 80...

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Mahadimane PV, Vasudev V. Inducible Protective Processes in Animal Systems XIII: Comparative Analysis of Induction of Adaptive Response by EMS and MMS in Ehrlich Ascites Carcinoma Cells. Scientifica (Cairo). 2014;2014:703136doi: 10.1155/2014/703136.
Mahadimane, P. V., & Vasudev, V. (2014). Inducible Protective Processes in Animal Systems XIII: Comparative Analysis of Induction of Adaptive Response by EMS and MMS in Ehrlich Ascites Carcinoma Cells. Scientifica, 2014703136. https://doi.org/10.1155/2014/703136
Mahadimane, Periyapatna Vishwaprakash, and Vasudev, Venkateshaiah. "Inducible Protective Processes in Animal Systems XIII: Comparative Analysis of Induction of Adaptive Response by EMS and MMS in Ehrlich Ascites Carcinoma Cells." Scientifica vol. 2014 (2014): 703136. doi: https://doi.org/10.1155/2014/703136
Mahadimane PV, Vasudev V. Inducible Protective Processes in Animal Systems XIII: Comparative Analysis of Induction of Adaptive Response by EMS and MMS in Ehrlich Ascites Carcinoma Cells. Scientifica (Cairo). 2014;2014:703136. doi: 10.1155/2014/703136. Epub 2014 Jun 04. PMID: 24999435; PMCID: PMC4066937.
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Mutagenic effectiveness and efficiency of EMS, DES and gamma-rays in rice.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Kaul ML, Bhan AK.
PMID: 24407841
Theor Appl Genet. 1977 Sep;50(5):241-6. doi: 10.1007/BF00273758.

Data on chlorophyll mutation frequency after treatment with EMS, DES and gamma-rays and sequential administration of gamma-rays and the two alkylating agents in three varieties of rice have been used to work out quantitatively the effectiveness and efficiency of...

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Kaul ML, Bhan AK. Mutagenic effectiveness and efficiency of EMS, DES and gamma-rays in rice. Theor Appl Genet. 1977;50(5):241-6doi: 10.1007/BF00273758.
Kaul, M. L., & Bhan, A. K. (1977). Mutagenic effectiveness and efficiency of EMS, DES and gamma-rays in rice. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 50(5), 241-6. https://doi.org/10.1007/BF00273758
Kaul, M L, and Bhan, A K. "Mutagenic effectiveness and efficiency of EMS, DES and gamma-rays in rice." TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik vol. 50,5 (1977): 241-6. doi: https://doi.org/10.1007/BF00273758
Kaul ML, Bhan AK. Mutagenic effectiveness and efficiency of EMS, DES and gamma-rays in rice. Theor Appl Genet. 1977 Sep;50(5):241-6. doi: 10.1007/BF00273758. PMID: 24407841.
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Alkylsilyl Peroxides as Alkylating Agents in the Copper-Catalyzed Selective Mono-N-Alkylation of Primary Amides and Arylamines.

Chemistry (Weinheim an der Bergstrasse, Germany)

Sakamoto R, Sakurai S, Maruoka K.
PMID: 28523837
Chemistry. 2017 Jul 06;23(38):9030-9033. doi: 10.1002/chem.201702217. Epub 2017 Jun 20.

The copper-catalyzed selective mono-N-alkylation of primary amides or arylamines using alkylsilyl peroxides as alkylating agents is reported. The reaction proceeds under mild reaction conditions and exhibits a broad substrate scope with respect to the alkylsilyl peroxides, as well as...

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Sakamoto R, Sakurai S, Maruoka K. Alkylsilyl Peroxides as Alkylating Agents in the Copper-Catalyzed Selective Mono-N-Alkylation of Primary Amides and Arylamines. Chemistry. 2017;23(38):9030-9033doi: 10.1002/chem.201702217.
Sakamoto, R., Sakurai, S., & Maruoka, K. (2017). Alkylsilyl Peroxides as Alkylating Agents in the Copper-Catalyzed Selective Mono-N-Alkylation of Primary Amides and Arylamines. Chemistry (Weinheim an der Bergstrasse, Germany), 23(38), 9030-9033. https://doi.org/10.1002/chem.201702217
Sakamoto, Ryu, et al. "Alkylsilyl Peroxides as Alkylating Agents in the Copper-Catalyzed Selective Mono-N-Alkylation of Primary Amides and Arylamines." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 23,38 (2017): 9030-9033. doi: https://doi.org/10.1002/chem.201702217
Sakamoto R, Sakurai S, Maruoka K. Alkylsilyl Peroxides as Alkylating Agents in the Copper-Catalyzed Selective Mono-N-Alkylation of Primary Amides and Arylamines. Chemistry. 2017 Jul 06;23(38):9030-9033. doi: 10.1002/chem.201702217. Epub 2017 Jun 20. PMID: 28523837.
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Chemotherapy-induced endometrial pathology: mimicry of malignancy and viral endometritis.

American journal of translational research

Kim EK, Yoon G, Kim HS.
PMID: 27347355
Am J Transl Res. 2016 May 15;8(5):2459-67. eCollection 2016.

Chemotherapy is a common type of preoperative neoadjuvant treatment and postoperative adjuvant or palliative therapy for many different types of malignancies. Certain chemotherapeutic agents can induce bizarre epithelial atypia that mimics malignancy. Unfamiliarity with these changes could potentially cause...

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Kim EK, Yoon G, Kim HS. Chemotherapy-induced endometrial pathology: mimicry of malignancy and viral endometritis. Am J Transl Res. 2016;8(5):2459-67
Kim, E. K., Yoon, G., & Kim, H. S. (2016). Chemotherapy-induced endometrial pathology: mimicry of malignancy and viral endometritis. American journal of translational research, 8(5), 2459-67.
Kim, Eun Kyung, et al. "Chemotherapy-induced endometrial pathology: mimicry of malignancy and viral endometritis." American journal of translational research vol. 8,5 (2016): 2459-67.
Kim EK, Yoon G, Kim HS. Chemotherapy-induced endometrial pathology: mimicry of malignancy and viral endometritis. Am J Transl Res. 2016 May 15;8(5):2459-67. eCollection 2016. PMID: 27347355; PMCID: PMC4891460.
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18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation.

Genes & nutrition

Mahmoud AM, Al Dera HS.
PMID: 26386843
Genes Nutr. 2015 Nov;10(6):41. doi: 10.1007/s12263-015-0491-1. Epub 2015 Sep 19.

18β-Glycyrrhetinic acid (18β-GA) has been proposed as a promising hepatoprotective agent. The current study aimed to investigate the protective action and the possible mechanisms of 18β-GA against cyclophosphamide (CP)-induced liver injury in rats, focusing on the role of peroxisome...

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Mahmoud AM, Al Dera HS. 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation. Genes Nutr. 2015;10(6):41doi: 10.1007/s12263-015-0491-1.
Mahmoud, A. M., & Al Dera, H. S. (2015). 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation. Genes & nutrition, 10(6), 41. https://doi.org/10.1007/s12263-015-0491-1
Mahmoud, Ayman M, and Al Dera, Hussein S. "18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation." Genes & nutrition vol. 10,6 (2015): 41. doi: https://doi.org/10.1007/s12263-015-0491-1
Mahmoud AM, Al Dera HS. 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation. Genes Nutr. 2015 Nov;10(6):41. doi: 10.1007/s12263-015-0491-1. Epub 2015 Sep 19. PMID: 26386843; PMCID: PMC4575654.
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Cyclic Enecarbamates as Precursors of α,β-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems.

The Journal of organic chemistry

Wang Z, Krogsgaard-Larsen N, Daniels B, Furkert DP, Brimble MA.
PMID: 27441647
J Org Chem. 2016 Nov 04;81(21):10366-10375. doi: 10.1021/acs.joc.6b01343. Epub 2016 Aug 01.

The scalable synthesis of cyclic enecarbamates and their use as convenient precursors of α,β-unsaturated N-acyl iminium ions is reported. The newly developed route overcomes synthetic and reactivity difficulties in previously reported methods, is readily scaled up, and proceeds through...

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Wang Z, Krogsgaard-Larsen N, Daniels B, et al. Cyclic Enecarbamates as Precursors of α,β-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems. J Org Chem. 2016;81(21):10366-10375doi: 10.1021/acs.joc.6b01343.
Wang, Z., Krogsgaard-Larsen, N., Daniels, B., Furkert, D. P., & Brimble, M. A. (2016). Cyclic Enecarbamates as Precursors of α,β-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems. The Journal of organic chemistry, 81(21), 10366-10375. https://doi.org/10.1021/acs.joc.6b01343
Wang, Zhanwei, et al. "Cyclic Enecarbamates as Precursors of α,β-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems." The Journal of organic chemistry vol. 81,21 (2016): 10366-10375. doi: https://doi.org/10.1021/acs.joc.6b01343
Wang Z, Krogsgaard-Larsen N, Daniels B, Furkert DP, Brimble MA. Cyclic Enecarbamates as Precursors of α,β-Unsaturated Iminium Ions: Reactivity and Synthesis of 6,6-Spirocyclic Ring Systems. J Org Chem. 2016 Nov 04;81(21):10366-10375. doi: 10.1021/acs.joc.6b01343. Epub 2016 Aug 01. PMID: 27441647.
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Haematologic Malignancy Secondary to the Treatment of Lymphoma.

Hematology (Amsterdam, Netherlands)

Aronson I, Jacobs P.
PMID: 27406426
Hematology. 1996;1(2):117-24. doi: 10.1080/10245332.1996.11746295.

Modern-day treatment for the malignant lymphomas has resulted in an improved remission rate and survival. However, in the longer run, many of these regimens are associated with a significant incidence of secondary haematologic malignancies. This study further defines this...

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Aronson I, Jacobs P. Haematologic Malignancy Secondary to the Treatment of Lymphoma. Hematology. 1996;1(2):117-24doi: 10.1080/10245332.1996.11746295.
Aronson, I., & Jacobs, P. (1996). Haematologic Malignancy Secondary to the Treatment of Lymphoma. Hematology (Amsterdam, Netherlands), 1(2), 117-24. https://doi.org/10.1080/10245332.1996.11746295
Aronson, I, and Jacobs, P. "Haematologic Malignancy Secondary to the Treatment of Lymphoma." Hematology (Amsterdam, Netherlands) vol. 1,2 (1996): 117-24. doi: https://doi.org/10.1080/10245332.1996.11746295
Aronson I, Jacobs P. Haematologic Malignancy Secondary to the Treatment of Lymphoma. Hematology. 1996;1(2):117-24. doi: 10.1080/10245332.1996.11746295. PMID: 27406426.
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Showing 1 to 12 of 502 entries