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Showing 1 to 12 of 35 entries
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Short-contact anthralin therapy for psoriasis.

The Western journal of medicine

Fleischmann HE.
PMID: 18750341
West J Med. 1987 Oct;147(4):461.

No abstract available.

Alopecia areata treated with phenolisation and intravenous dexamethasone pulses.

International journal of trichology

Kar S, Singh N.
PMID: 23960401
Int J Trichology. 2013 Jan;5(1):47-9. doi: 10.4103/0974-7753.114708.

Phenol is an aromatic hydrocarbon derived from coal tar or manufactured from monochlorobenzene. Alopecia areata is a common non scarring autoimmune condition characterised by patchy loss of hair without atrophy. Various treatment modalities have been proposed and used for...

Toxicity of structurally related anthraquinones and anthrones to mammalian cells in vitro.

Toxicology in vitro : an international journal published in association with BIBRA

Bondy GS, Armstrong CL, Dawson BA, Héroux-Metcalf C, Neville GA, Rogers CG.
PMID: 20692923
Toxicol In Vitro. 1994 Jun;8(3):329-35. doi: 10.1016/0887-2333(94)90153-8.

Anthraquinones and structurally related compounds were cytotoxic to mammalian cell lines using cloning efficiency and MTT reduction as endpoints. In V79 cells, the concentration of chemical causing 50% inhibition ranged from 0.21 to 21.6 mug/ml for cloning efficiency and...

Making a bat: The developmental basis of bat evolution.

Genetics and molecular biology

Sadier A, Urban DJ, Anthwal N, Howenstine AO, Sinha I, Sears KE.
PMID: 33576369
Genet Mol Biol. 2021 Feb 08;43(1):e20190146. doi: 10.1590/1678-4685-GMB-2019-0146. eCollection 2021.

Bats are incredibly diverse, both morphologically and taxonomically. Bats are the only mammalian group to have achieved powered flight, an adaptation that is hypothesized to have allowed them to colonize various and diverse ecological niches. However, the lack of...

Combination of topical anthralin and calcipotriene in alopecia areata: A discussion of the mechanisms of action.

JAAD case reports

Yao CA.
PMID: 32743037
JAAD Case Rep. 2020 May 22;6(7):673-674. doi: 10.1016/j.jdcr.2020.05.022. eCollection 2020 Jul.

No abstract available.

Syntheses of Anthracenones. 2. Preparation of 1,8-Dimethoxy- (Dimethylanthralin) and 4,5-Dihydroxy-9(10H)-anthracenone (Isoanthralin): A Revision.

The Journal of organic chemistry

Prinz H, Burgemeister T, Wiegrebe W, Müller K.
PMID: 11667123
J Org Chem. 1996 Apr 19;61(8):2857-2860. doi: 10.1021/jo952036t.

The reduction of 1,8-dimethoxyanthracenedione with zinc dust and aqueous ammonia gives a mixture of 1,8-dimethoxyanthracene and 4,5-dimethoxy-9(10H)-anthracenone, rather than the isomeric 1,8-dimethoxy-9(10H)-anthracenone (dimethylanthralin). This isomer was obtained exclusively using SnCl(2) in HCl and acetic acid as reducing agent at...

Psoriasis.

Drugs of today (Barcelona, Spain : 1998)

Tan MH, Lebwohl M.
PMID: 14988763
Drugs Today (Barc). 1998 Jul;34(7):641-7. doi: 10.1358/dot.1998.34.7.485262.

Psoriasis is an inflammatory disorder of the skin that involves complex interactions between the dermis and epidermis. There are several forms of psoriasis, the most common being plaque type psoriasis. Other forms include guttate, pustular and erythrodermic psoriasis. Both...

Topical Therapies in Psoriasis.

Indian dermatology online journal

Torsekar R, Gautam MM.
PMID: 28761838
Indian Dermatol Online J. 2017 Jul-Aug;8(4):235-245. doi: 10.4103/2229-5178.209622.

Topical therapy as monotherapy is useful in psoriasis patients with mild disease. Topical agents are also used as adjuvant for moderate-to-severe disease who are being concurrently treated with either ultraviolet light or systemic medications. Emollients are useful adjuncts to...

How Chemical Environment Activates Anthralin and Molecular Oxygen for Direct Reaction.

The Journal of organic chemistry

Ellis ES, MacHale LT, Szilagyi RK, DuBois JL.
PMID: 31830417
J Org Chem. 2020 Jan 17;85(2):1315-1321. doi: 10.1021/acs.joc.9b03133. Epub 2019 Dec 20.

The role of the chemical environment in promoting anthralin/O

Extensive alopecia areata: not necessarily recalcitrant to therapy!.

International journal of trichology

Deshpande D, Dhurat R, Saraogi P, Mishra S, Nayak C.
PMID: 22223966
Int J Trichology. 2011 Jul;3(2):80-3. doi: 10.4103/0974-7753.90807.

BACKGROUND: Extensive alopecia areata includes alopecia universalis, alopecia totalis, ophiasis and patients having more than 50% scalp involvement. Alopecia universalis (AU) and totalis (AT) are considered to be resistant to single modalities of treatment. Our study highlights the efficacy...

Meckel's cartilage breakdown offers clues to mammalian middle ear evolution.

Nature ecology & evolution

Anthwal N, Urban DJ, Luo ZX, Sears KE, Tucker AS.
PMID: 28459103
Nat Ecol Evol. 2017 Mar 06;1(4):93. doi: 10.1038/s41559-017-0093.

A key transformation in mammalian ear evolution was incorporation of the primary jaw joint of premammalian synapsids into the definitive mammalian middle ear of living mammals. This evolutionary transition occurred in two-steps, starting with a partial or "transitional" mammalian...

Dissociative Electron Attachment to Anthralin to Model Its Biochemical Reactions.

The journal of physical chemistry letters

Pshenichnyuk SA, Komolov AS.
PMID: 26278099
J Phys Chem Lett. 2014 Aug 21;5(16):2916-21. doi: 10.1021/jz501523s. Epub 2014 Aug 13.

The antipsoriatic drug anthralin (dithranol) is known to be extensively accumulated inside mitochondria of keratinocytes and to interact with the electron flow of the respiratory chain. Primary products of the one-electron reduction of polyphenolic anthralin observed in vivo are...

Showing 1 to 12 of 35 entries