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Showing 1 to 8 of 8 entries
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The Practical Consideration of Poliovirus as an Oncolytic Virotherapy.

American journal of virology

Denniston E, Crewdson H, Rucinsky N, Stegman A, Remenar D, Moio K, Clark B, Higginbotham A, Keffer R, Brammer S, Horzempa J.
PMID: 28203321
Am J Virol. 2016;5(1):1-7. doi: 10.3844/ajvsp.2016.1.7. Epub 2016 Mar 03.

The inauguration of novel treatment strategies into the clinical setting faces a number of hurdles. In addition to treatment efficacy and safety, acceptance by doctors and patients is paramount to the success of novel therapies. Although viruses are the...

Adoptive T Cell Therapy Targeting CD1 and MR1.

Frontiers in immunology

Guo T, Chamoto K, Hirano N.
PMID: 26052329
Front Immunol. 2015 May 20;6:247. doi: 10.3389/fimmu.2015.00247. eCollection 2015.

Adoptive T cell immunotherapy has demonstrated clinically relevant efficacy in treating malignant and infectious diseases. However, much of these therapies have been focused on enhancing, or generating de novo, effector functions of conventional T cells recognizing HLA molecules. Given...

Effect of GM-CSF, 1, 25-Dihydroxycholecalciferol (Vit.D) and All-Trans-Retinoic Acid (ATRA) on the Proliferation and Differentiation of MDS-Bone Marrow (BM)-Cells In Vitro.

Hematology (Amsterdam, Netherlands)

Schmetzer HM, Rapp L, Wilmanns W, Gerhartz HH.
PMID: 27406722
Hematology. 1997;2(1):11-9. doi: 10.1080/10245332.1997.11746315.

Myelodysplastic syndromes (MDS) are a heterogenous group of stem cell disorders characterized by an impaired differentiation of the pluripotent stem cell resulting in dysplastic changes of all three hemopoietic lineages. We studied the effect of vitamin D (Vit.D) or...

Distinctive Pattern of Expression of Activation and Resting B Cell Antigens on Normal and Neoplastic Human B Cells: Immunophenotypic Heterogeneity in Some Lymphomas.

Leukemia & lymphoma

Kiyokawa N, Kokai Y, Kikuchi K, Fujita H, Hata J, Fujimoto J.
PMID: 27457297
Leuk Lymphoma. 1990;3(2):119-26. doi: 10.3109/10428199009050985.

The pattern of expression of four B cell antigen systems on mature human B cells and B cell lymphomas were studied. The L30 antigen was detected on small resting B cells, while the B cell activation antigens, CD10, CD25...

CAL-1 as Cellular Model System to Study CCR7-Guided Human Dendritic Cell Migration.

Frontiers in immunology

Uetz-von Allmen E, Samson GPB, Purvanov V, Maeda T, Legler DF.
PMID: 34603281
Front Immunol. 2021 Sep 16;12:702453. doi: 10.3389/fimmu.2021.702453. eCollection 2021.

Dendritic cells (DCs) are potent and versatile professional antigen-presenting cells and central for the induction of adaptive immunity. The ability to migrate and transport peripherally acquired antigens to draining lymph nodes for subsequent cognate T cell priming is a...

The diagnostic profile of rare acute myelomegakaryoblastic leukemia.

Leukemia & lymphoma

Xu DM, Yu WJ, Xie L, Zhang ZW, Qiu JF, Xu CW, He CL, Xu XR, Xu JS, Li Q, Yin J.
PMID: 34477034
Leuk Lymphoma. 2021 Dec;62(13):3204-3211. doi: 10.1080/10428194.2021.1955878. Epub 2021 Sep 03.

Acute myelomagakaryocytic leukemia is a diagnostic and therapeutic challenge owing to its heterogeneity and overlapping features with other types of acute leukemia. In order to build a diagnostic profile, we analyzed the biological, clinical and hematologic characteristics of acute...

Isolation and Characterization of Multipotent Canine Urine-Derived Stem Cells.

Stem cells international

Xu Y, Zhang T, Chen Y, Shi Q, Li M, Qin T, Hu J, Lu H, Liu J, Chen C.
PMID: 33061993
Stem Cells Int. 2020 Sep 30;2020:8894449. doi: 10.1155/2020/8894449. eCollection 2020.

Current cell-based therapies on musculoskeletal tissue regeneration were mostly determined in rodent models. However, a direct translation of those promising cell-based therapies to humans exists a significant hurdle. For solving this problem, canine has been developed as a new...

Interdigitating Reticulum Cell Sarcoma Positive immunohistochemistry for HLA-DR and two other activation antigens, CD30(Ki-1) and CD25(IL2R).

Leukemia & lymphoma

Papadimitriou CS, Bai MC, Stephanou DG, Pavlidis NA, Athanasiadou SE.
PMID: 27467676
Leuk Lymphoma. 1991;4(5):411-7. doi: 10.3109/10428199109068094.

This communication reports a case of the rare interdigitating reticulum cell (IDRC) sarcoma of lymph nodes in a 46-year-old man. Extensive immunophenotypic analysis on paraffin and frozen sections revealed positivity on the neoplastic cells for protein S-100 as well...

Showing 1 to 8 of 8 entries