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Showing 1 to 12 of 55863 entries
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Oocyte apoptosis during the transition from ovary-like tissue to testes during sex differentiation of juvenile zebrafish

STEM and males

[No authors listed]
GSID: prUScg6ihqsJ
D Uchida, M Yamashita, T Kitano… - Journal of Experimental …, 2002 - journals.biologists.com

… apoptotic oocytes in the gonads of presumptive males was approximately eight- to 12-fold … from the gonads of presumptive males. In these males, we also observed apoptotic somatic …

Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis

Science interventions

[No authors listed]
GSID: TvN9G5uwwdwJ
RH Zhang, JY Gao, HT Guo, GI Scott, AR Eason… - … et Biophysica Acta (BBA …, 2013 - Elsevier

Alcohol intake is associated with myocardial contractile dysfunction and apoptosis although the precise mechanism is unclear. This study was designed to examine the effect of the …

Bax and Bcl-XL apoptosis protein mRNA in rat brain stem and cortex during ontogeny

STEM and men

[No authors listed]
GSID: tJdpwmFPykIJ
AV Bannova, PN Men'Shanov, FA Il'inykh… - Bulletin of Experimental …, 2005 - Springer

Bax mRNA level in fetal rat brain stem increases by day 40 of life and then decreases, while level of Bcl-X L mRNA reaches the adult value over one month. Bax mRNA level in the …

… Radiation Induces Ataxia Telangiectasia Mutated-Dependent Checkpoint Signaling and G2 But Not G1 Cell Cycle Arrest in Pluripotent Human Embryonic Stem …

Graduate training programs stem

Bakkenist C, Choi S, Varum S.
GSID: sNT2S95F9GYJ
O Momčilović, S Choi, S Varum, C Bakkenist… - Stem Cells, 2009 - academic.oup.com

Human embryonic stem (ES) cells are highly sensitive to environmental insults including DNA damaging agents, responding with high levels of apoptosis. To understand the response …

… : Current address of Dr. Karin M. Kirschner is at Johannes-Müller Institut fu̇r Physiologie, Charité-Universitätsmedizin Berlin, Campus Charité-Mitte, Tucholskystrasse …

science campus

[No authors listed]
GSID: 1s73hdO2Rq8J
KM Kirschner, K Baltensperger - Molecular cancer research, 2003 - AACR

Chronic myeloid leukemia is characterized by the Philadelphia chromosome translocation that causes expression of Bcr-Abl, a deregulated tyrosine kinase. Imatinib mesylate (STI571, Gleevec), a therapeutically used inhibitor of Bcr-Abl, causes apoptosis of Bcr-Abl-positive cells…

Molecular signaling mechanisms of apoptosis in hereditary non-polyposis colorectal cancer

EPSCoR Research Infrastructure Improvement Program AND Program Evaluation

Ali N, Chowdhury P.
GSID: Op7DjUZy-JUJ
S Hassen, N Ali, P Chowdhury - World journal of gastrointestinal …, 2012 - ncbi.nlm.nih.gov

Colorectal cancer is the second most leading cause of cancer related deaths in the western countries. One of the forms of colorectal cancer is hereditary non-polyposis colorectal cancer (HNPCC), also known as “Lynch syndrome”. It is the most common...

Immunomodulatory effects of the botanical compound LCS101: implications for cancer treatment.

OncoTargets and therapy

Rachmut IH, Samuels N, Melnick SJ, Ramachandran C, Sharabi Y, Pavlovsky A, Maimon Y, Shoham J.
PMID: 23637542
Onco Targets Ther. 2013 Apr 24;6:437-45. doi: 10.2147/OTT.S42038. Print 2013.

OBJECTIVE: To examine the effects of LSC101, a botanical compound, on adaptive and innate immunity.MATERIALS AND METHODS: LCS101 preparations were tested for batch-to-batch consistency using high-performance liquid chromatography. T-cell activation was quantified in murine spleen cells using 3H-thymidine incorporation,...

Application of sustained delivery microsphere of cyclosporine A for preventing posterior capsular opacification in rabbits.

International journal of ophthalmology

Pei C, Xu Y, Jiang JX, Cui LJ, Li L, Qin L.
PMID: 23550193
Int J Ophthalmol. 2013;6(1):1-7. doi: 10.3980/j.issn.2222-3959.2013.01.01. Epub 2013 Feb 18.

AIM: To explore the inhibitory effect of a sustained cyclosporin A (CsA) delivery microsphere (CsA-MS) on posterior capsular opacification (PCO) in rabbit eyes after cataract extraction.METHODS: Twenty New Zealand white rabbits accepted cataract extraction plus intraocular lens implantation and...

"Dead Cells Talking": The Silent Form of Cell Death Is Not so Quiet.

Biochemistry research international

Jäger R, Fearnhead HO.
PMID: 22919490
Biochem Res Int. 2012;2012:453838. doi: 10.1155/2012/453838. Epub 2012 Aug 07.

After more than twenty years of research, the molecular events of apoptotic cell death can be succinctly stated; different pathways, activated by diverse signals, increase the activity of proteases called caspases that rapidly and irreversibly dismantle condemned cell by...

Logical network of genotoxic stress-induced NF-κB signal transduction predicts putative target structures for therapeutic intervention strategies.

Advances and applications in bioinformatics and chemistry : AABC

Poltz R, Franke R, Schweitzer K, Klamt S, Gilles ED, Naumann M.
PMID: 21918620
Adv Appl Bioinform Chem. 2009;2:125-38. doi: 10.2147/aabc.s8211. Epub 2009 Dec 03.

Genotoxic stress is induced by a broad range of DNA-damaging agents and could lead to a variety of human diseases including cancer. DNA damage is also therapeutically induced for cancer treatment with the aim to eliminate tumor cells. However,...

Pancreas procurement and preservation for islet transplantation: personal considerations.

Journal of transplantation

Noguchi H.
PMID: 21918716
J Transplant. 2011;2011:783168. doi: 10.1155/2011/783168. Epub 2011 Sep 12.

Pancreatic islet transplantation is a promising option for the treatment of type 1 diabetic patients. After the successful demonstration of the Edmonton protocol, islet transplantation has advanced significantly on several fronts, including improved pancreas procurement and preservation systems. Since...

Association of FAS gene polymorphisms with systemic lupus erythematosus: A case-control study and meta-analysis.

Experimental and therapeutic medicine

Lu MM, Ye QL, Feng CC, Yang J, Zhang T, Li J, Leng RX, Pan HF, Yuan H, Ye DQ.
PMID: 23181125
Exp Ther Med. 2012 Sep;4(3):497-502. doi: 10.3892/etm.2012.625. Epub 2012 Jun 28.

The association of functional polymorphisms in the promoter of the apoptosis gene FAS with systemic lupus erythematosus (SLE) susceptibility has been a controversial subject. We conducted a case-control study to investigate this association in a Chinese population and performed...

Showing 1 to 12 of 55863 entries