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Showing 1 to 12 of 8864 entries
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Weekly cisplatin may reverse liver dysfunction and jaundice caused by diffuse liver metastases of solid tumors.

Hepatic medicine : evidence and research

Gabrovska M, Geurs F, Ponette S, Ponette J, Bulte K, Derveaux L, Kempeneers I.
PMID: 24623997
Hepat Med. 2009 Oct 30;1:9-12. doi: 10.2147/hmer.s7574. eCollection 2009.

Few data are available on patient management in jaundice caused by liver metastases of solid tumors (nonbreast and noncolon origin). We report the first patient series consecutively treated with cisplatin weekly in patients with severe jaundice and liver failure...

Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin.

Journal of oncology

Sharma C, Vas AJ, Goala P, Gheewala TM, Rizvi TA, Hussain A.
PMID: 24624140
J Oncol. 2014;2014:321754. doi: 10.1155/2014/321754. Epub 2014 Jan 30.

The present study was designed to gain insight into the antiproliferative activity of ethanolic neem leaves extract (ENLE) alone or in combination with cisplatin by cell viability assay on human breast (MCF-7) and cervical (HeLa) cancer cells. Nuclear morphological...

Cisplatin combined with irinotecan or etoposide for untreated extensive-stage small cell lung cancer: A multicenter randomized controlled clinical trial.

Thoracic cancer

Shi Y, Hu Y, Hu X, Li X, Lin L, Han X.
PMID: 26557919
Thorac Cancer. 2015 Nov;6(6):785-91. doi: 10.1111/1759-7714.12303. Epub 2015 Aug 20.

BACKGROUND: This study evaluated the efficacy and safety of irinotecan/cisplatin (IP) and etoposide/cisplatin (EP) in extensive-stage small cell lung cancer (ES-SCLC) and the distribution of uridine diphosphate glucuronosyltransferase (UGT1A1). The relationship between UGT1A1 genotypes and patient outcomes was also...

Amphricrine carcinoma of the cervix-adeno neuroendocrine tumor: A case report.

Turkish journal of obstetrics and gynecology

Fadıloğlu E, Karalök A, Türkmen O, Asiltürk Ş, Öçalan R, Boran N, Ökten H, Turan T, Tulunay G.
PMID: 28913101
Turk J Obstet Gynecol. 2016 Jun;13(2):99-102. doi: 10.4274/tjod.72325. Epub 2016 Jun 15.

Adenoneuroendocrine carcinoma is a very rare form of cervical carcinoma that includes both endocrine and exocrine components. In general terms, these carcinomas progress aggressively and show early metastases due to the neuroendocrine component. The most important criteria related to...

LncRNA plasmacytoma variant translocation 1 is an oncogene in bladder urothelial carcinoma.

Oncotarget

Liu Z, Zhang H.
PMID: 28969069
Oncotarget. 2017 Jul 26;8(38):64273-64282. doi: 10.18632/oncotarget.19604. eCollection 2017 Sep 08.

Bladder cancer (BC) is the most lethal malignant cancer of the genitourinary system, and bladder urothelial carcinoma (BUC) is the most common type of BC. The long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) is overexpressed in several...

TCRP1 expression is associated with platinum sensitivity in human lung and ovarian cancer cells.

Oncology letters

Liu X, Feng M, Zheng G, Gu Y, Wang C, He Z.
PMID: 28454268
Oncol Lett. 2017 Mar;13(3):1398-1405. doi: 10.3892/ol.2016.5534. Epub 2016 Dec 27.

Platinum-based drugs, including cisplatin (DDP) and oxaliplatin (L-OHP), are among the most potent chemotherapy drugs, and are widely utilized for the treatment of human lung and ovarian cancer. However, certain patients do not respond to platinum-based agents, and even...

MicroRNA-134 reverses multidrug resistance in human lung adenocarcinoma cells by targeting FOXM1.

Oncology letters

Li J, Chen Y, Jin M, Wang J, Li S, Chen Z, Yu W.
PMID: 28454276
Oncol Lett. 2017 Mar;13(3):1451-1455. doi: 10.3892/ol.2017.5574. Epub 2017 Jan 05.

Multidrug resistance (MDR) is the primary barrier to the success of chemotherapy for lung adenocarcinoma. MicroRNA (miR)-134, which is downregulated in lung adenocarcinoma, influences cell proliferation, apoptosis and invasion of lung adenocarcinoma. However, the function of miR-134 in the...

Human mesenchymal stem cells are resistant to cytotoxic and genotoxic effects of cisplatin in vitro.

Genetics and molecular biology

Bellagamba BC, Abreu BR, Grivicich I, Markarian CF, Chem E, Camassola M, Nardi NB, Dihl RR.
PMID: 27007906
Genet Mol Biol. 2016 Mar;39(1):129-34. doi: 10.1590/1678-4685-GMB-2015-0057.

Mesenchymal stem cells (MSCs) are known for their important properties involving multilineage differentiation potential., trophic factor secretion and localization along various organs and tissues. On the dark side, MSCs play a distinguished role in tumor microenvironments by differentiating into...

Gimeracil enhances the antitumor effect of cisplatin in oral squamous cell carcinoma cells .

Oncology letters

Harada K, Ferdous T, Harada T, Takenawa T, Ueyama Y.
PMID: 28927087
Oncol Lett. 2017 Sep;14(3):3349-3356. doi: 10.3892/ol.2017.6602. Epub 2017 Jul 18.

Gimeracil or 5-chloro-2,4-dihydroxypyridine (CDHP) enhances the antitumor effects of 5-fluorouracil (5-FU) by inhibiting dihydropyrimidine dehydrogenase (DPD), which is involved in the degradation of 5-FU. CDHP, as part of a combination therapy, was also reported to exert a radiosensitizing effect....

Benefit of rebiopsy for deciding treatment strategy in rectal cancer: A case report.

Oncology letters

Kawasaki K, Hamamoto Y, Suzuki T, Hirata K, Sukawa Y, Kasuga A, Hayashi Y, Takaishi H, Kameyama K, Kanai T.
PMID: 28927133
Oncol Lett. 2017 Sep;14(3):3697-3700. doi: 10.3892/ol.2017.6601. Epub 2017 Jul 18.

Rebiopsy is considered an option for specific types of cancer, such as breast, non-small cell lung, and prostate cancer, in clinical trials and in practice. The benefit of rebiopsy comes from the selection of a new treatment strategy based...

Correction to Synergistic Anticancer Activity of Fluorescent Copper Nanoclusters and Cisplatin Delivered through a Hydrogel Nanocarrier.

ACS applied materials & interfaces

Ghosh R, Goswami U, Ghosh SS, Paul A, Chattopadhyay A.
PMID: 26376604
ACS Appl Mater Interfaces. 2015 Sep 30;7(38):21626. doi: 10.1021/acsami.5b08088. Epub 2015 Sep 17.

No abstract available.

Erratum to: Phase I and pharmacokinetic evaluation of the anti-telomerase agent KML-001 with cisplatin in advanced solid tumors.

Cancer chemotherapy and pharmacology

Edelman MJ, Lapidus R, Feliciano J, Styblo M, Beumer JH, Liu T, Gobburu J.
PMID: 27677624
Cancer Chemother Pharmacol. 2016 Nov;78(5):969. doi: 10.1007/s00280-016-3159-7.

No abstract available.

Showing 1 to 12 of 8864 entries