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Showing 1 to 12 of 1777 entries
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Stress in farmed saltwater crocodiles (Crocodylus porosus): no difference between individually- and communally-housed animals.

SpringerPlus

Isberg SR, Shilton CM.
PMID: 24010039
Springerplus. 2013 Aug 13;2:381. doi: 10.1186/2193-1801-2-381. eCollection 2013.

Minimising stress in farmed crocodiles is not only important for improving animal welfare, but may also improve skin blemish healing and infection resistance, which influence the quality of the final skin product. Forty near-harvest size saltwater crocodiles (1.6-1.8 m...

Sound-stress-induced altered nociceptive behaviors are associated with increased spinal CRFR2 gene expression in a rat model of burn injury.

Journal of pain research

Sosanya NM, Trevino AV, Chavez RL, Christy RJ, Cheppudira BP.
PMID: 28979159
J Pain Res. 2017 Sep 01;10:2135-2145. doi: 10.2147/JPR.S144055. eCollection 2017.

Sound stress (SS) elicits behavioral changes, including pain behaviors. However, the neuronal mechanisms underlying SS-induced pain behaviors remain to be explored. The current study examined the effects of SS on nociceptive behaviors and changes in expression of the spinal...

Nitric Oxide Synthase Inhibitor Attenuates the Effects of Repeated Restraint Stress on Synaptic Transmission in the Paraventricular Nucleus of the Rat Hypothalamus.

Frontiers in cellular neuroscience

Kusek M, Tokarska A, Siwiec M, Gadek-Michalska A, Szewczyk B, Hess G, Tokarski K.
PMID: 28515682
Front Cell Neurosci. 2017 May 03;11:127. doi: 10.3389/fncel.2017.00127. eCollection 2017.

Corticotropin-releasing hormone (CRH)-synthesizing parvocellular neuroendocrine cells (PNCs) of the hypothalamic paraventricular nucleus (PVN) play a key role in the activation of the hypothalamic-pituitary-adrenocortical (HPA) axis. Several studies have demonstrated that synaptic inputs to these cells may undergo stress-related enhancement...

Predictable enriched environment prevents development of hyper-emotionality in the VPA rat model of autism.

Frontiers in neuroscience

Favre MR, La Mendola D, Meystre J, Christodoulou D, Cochrane MJ, Markram H, Markram K.
PMID: 26089770
Front Neurosci. 2015 Jun 02;9:127. doi: 10.3389/fnins.2015.00127. eCollection 2015.

Understanding the effects of environmental stimulation in autism can improve therapeutic interventions against debilitating sensory overload, social withdrawal, fear and anxiety. Here, we evaluate the role of environmental predictability on behavior and protein expression, and inter-individual differences, in the...

Emulsified isoflurane anesthesia decreases brain-derived neurotrophic factor expression and induces cognitive dysfunction in adult rats.

Experimental and therapeutic medicine

Zhang F, Zhu ZQ, Liu DX, Zhang C, Gong QH, Zhu YH.
PMID: 25009603
Exp Ther Med. 2014 Aug;8(2):471-477. doi: 10.3892/etm.2014.1769. Epub 2014 Jun 10.

Post-operative cognitive dysfunction (POCD) is a severe complication characterized by cognitive decline in patients following anesthesia and surgery. Previous studies have suggested that volatile anesthetics, for example isoflurane, may contribute to such impairment. In the present study, the effects...

Antidepressant activity of fingolimod in mice.

Pharmacology research & perspectives

di Nuzzo L, Orlando R, Tognoli C, Di Pietro P, Bertini G, Miele J, Bucci D, Motolese M, Scaccianoce S, Caruso A, Mauro G, De Lucia C, Battaglia G, Bruno V, Fabene PF, Nicoletti F.
PMID: 26171219
Pharmacol Res Perspect. 2015 Jun;3(3):e00135. doi: 10.1002/prp2.135. Epub 2015 May 24.

Recent findings indicate that fingolimod, the first oral drug approved for the treatment of multiple sclerosis (MS), acts as a direct inhibitor of histone deacetylases (HDACs) and enhances the production of brain-derived neurotrophic factor (BDNF) in the CNS. Both...

Effects of the recombinant allergen rDer f 2 on neuro-endocrino-immune network in asthmatic mice.

Central-European journal of immunology

Jiang YQ, Zhou ZX, Ji YL.
PMID: 26155138
Cent Eur J Immunol. 2014;39(3):294-8. doi: 10.5114/ceji.2014.45938. Epub 2014 Oct 14.

Severe and life-threatening side effects can occur in patients receiving allergen-specific immunotherapy (SIT), and recombinant allergens made from cDNA have been used in clinical trials for ten years and appear promising for SIT. The aim of this study is...

A practical field extraction method for non-invasive monitoring of hormone activity in the black rhinoceros.

Conservation physiology

Edwards KL, McArthur HM, Liddicoat T, Walker SL.
PMID: 27293621
Conserv Physiol. 2014 Feb 03;2(1):cot037. doi: 10.1093/conphys/cot037. eCollection 2014.

Non-invasive hormone analysis is a vital tool in assessing an animal's adrenal and reproductive status, which can be beneficial to in situ and ex situ conservation. However, it can be difficult to employ these techniques when monitoring in situ...

Effects of natural environmental conditions on faecal glucocorticoid metabolite concentrations in jaguars (Panthera onca) in Belize.

Conservation physiology

Mesa-Cruz JB, Brown JL, Kelly MJ.
PMID: 27293660
Conserv Physiol. 2014 Sep 09;2(1):cou039. doi: 10.1093/conphys/cou039. eCollection 2014.

In situ studies that rely on non-invasive faecal hormone monitoring are subject to problems due to potential changes in hormone concentrations in samples exposed to field conditions. In this study, we conducted an environmental validation for measurement of faecal...

Stress physiology of migrant birds during stopover in natural and anthropogenic woodland habitats of the Northern Prairie region.

Conservation physiology

Liu M, Swanson DL.
PMID: 27293667
Conserv Physiol. 2014 Oct 11;2(1):cou046. doi: 10.1093/conphys/cou046. eCollection 2014.

Anthropogenic alterations of woodland habitat may influence stopover biology, which in turn could alter the stress physiology of migratory landbirds. Woodland stopover habitats are scarce in the Northern Prairie region of North America and consist of native riparian corridor...

Chronic exposure to a low dose of ingested petroleum disrupts corticosterone receptor signalling in a tissue-specific manner in the house sparrow (Passer domesticus).

Conservation physiology

Lattin CR, Romero LM.
PMID: 27293679
Conserv Physiol. 2014 Dec 03;2(1):cou058. doi: 10.1093/conphys/cou058. eCollection 2014.

Stress-induced concentrations of glucocorticoid hormones (including corticosterone, CORT) can be suppressed by chronic exposure to a low dose of ingested petroleum. However, endocrine-disrupting chemicals could interfere with CORT signalling beyond the disruption of hormone titres, including effects on receptors...

Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response.

Molecular metabolism

Rojas JM, Matsen ME, Mundinger TO, Morton GJ, Stefanovski D, Bergman RN, Kaiyala KJ, Taborsky GJ, Schwartz MW.
PMID: 26266088
Mol Metab. 2015 Jun 04;4(8):561-8. doi: 10.1016/j.molmet.2015.05.005. eCollection 2015 Aug.

OBJECTIVE: Central administration of ligands for fibroblast growth factor receptors (FGFRs) such as fibroblast growth factor-19 (FGF19) and FGF21 exert glucose-lowering effects in rodent models of obesity and type 2 diabetes (T2D). Conversely, intracerebroventricular (icv) administration of the non-selective...

Showing 1 to 12 of 1777 entries