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Showing 1 to 12 of 2009 entries
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Application of sustained delivery microsphere of cyclosporine A for preventing posterior capsular opacification in rabbits.

International journal of ophthalmology

Pei C, Xu Y, Jiang JX, Cui LJ, Li L, Qin L.
PMID: 23550193
Int J Ophthalmol. 2013;6(1):1-7. doi: 10.3980/j.issn.2222-3959.2013.01.01. Epub 2013 Feb 18.

AIM: To explore the inhibitory effect of a sustained cyclosporin A (CsA) delivery microsphere (CsA-MS) on posterior capsular opacification (PCO) in rabbit eyes after cataract extraction.METHODS: Twenty New Zealand white rabbits accepted cataract extraction plus intraocular lens implantation and...

Pre-treatment considerations in childhood hypertension due to chronic kidney disease.

World journal of nephrology

Olowu WA.
PMID: 26558187
World J Nephrol. 2015 Nov 06;4(5):500-10. doi: 10.5527/wjn.v4.i5.500.

Hypertension (HTN) develops very early in childhood chronic kidney disease (CKD). It is linked with rapid progression of kidney disease, increased morbidity and mortality hence the imperative to start anti-hypertensive medication when blood pressure (BP) is persistently > 90(th)...

Medical Therapy of Active Ulcerative Colitis.

Viszeralmedizin

Bürger M, Schmidt C, Teich N, Stallmach A.
PMID: 26557831
Viszeralmedizin. 2015 Aug;31(4):236-45. doi: 10.1159/000436959. Epub 2015 Aug 04.

BACKGROUND: Medical therapy of mild and moderate ulcerative colitis (UC) of any extent is evidence-based and standardized by national and international guidelines. However, patients with steroid-refractory UC still represent a challenge.METHODS: A literature search using PubMed (search terms: ulcerative...

Importance of Accurate Diagnosis in Pyoderma Gangrenosum.

Archives of craniofacial surgery

Kim YS, Kim HK, Han YS.
PMID: 28913208
Arch Craniofac Surg. 2014 Dec;15(3):138-141. doi: 10.7181/acfs.2014.15.3.138. Epub 2014 Dec 23.

Pyoderma gangrenosum is a rare inflammatory reactive dermatosis marked by painful cutaneous ulcers. Diagnosis of pyoderma gangrenosum is usually made based on past medical history and after the exclusion of other possible diseases based on the clinical manifestations of...

From chronic immune thrombocytopenia to severe aplastic anemia: recent insights into the evolution of eltrombopag.

Therapeutic advances in hematology

Gill H, Wong RSM, Kwong YL.
PMID: 28473904
Ther Adv Hematol. 2017 May;8(5):159-174. doi: 10.1177/2040620717693573. Epub 2017 Feb 01.

Thrombopoietin (TPO) is the most potent cytokine stimulating thrombopoiesis. Therapy with exogenous TPO is limited by the formation of antibodies cross-reacting with endogenous TPO. Mimetics of TPO are compounds with no antigenic similarity to TPO. Eltrombopag is an orally-active...

Chronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations.

Allergy, asthma & immunology research

Kaplan AP.
PMID: 28913986
Allergy Asthma Immunol Res. 2017 Nov;9(6):477-482. doi: 10.4168/aair.2017.9.6.477.

The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H₁-receptor blockers are typically employed up to 4 times a day. First-generation antihistamines, such as hydroxyzine...

The Relationship between Mortality of Lung Transplant Recipients and Serum Cyclosporine Levels: Joint Modeling of Time-to-Event Data and Longitudinal Data.

International journal of organ transplantation medicine

Hosseini-Baharanchi FS, Hajizadeh E, Baghestani AR, Najafzadeh K.
PMID: 28924464
Int J Organ Transplant Med. 2017;8(3):157-163. Epub 2017 Aug 01.

BACKGROUND: Lung transplantation (LTx) is a well-accepted treatment that can prolong survival of patients with advanced lung disease.OBJECTIVE: To evaluate the association between serum cyclosporine level (SCL) pattern and mortality of LTx recipients.METHODS: This retrospective cohort study included 1019...

Fascin-1 is released from proximal tubular cells in response to calcineurin inhibitors (CNIs) and correlates with isometric vacuolization in kidney transplanted patients.

American journal of translational research

Jacobs-Cachá C, Torres IB, López-Hellín J, Cantarell C, Azancot MA, Román A, Moreso F, Serón D, Meseguer A, Sarró E.
PMID: 28979691
Am J Transl Res. 2017 Sep 15;9(9):4173-4183. eCollection 2017.

Immunosuppression based on calcineurin inhibitors (CNIs) has greatly improved organ transplantation, although subsequent nephrotoxicity significantly hinders treatment success. There are no currently available specific soluble biomarkers for CNI-induced nephrotoxicity and diagnosis relies on renal biopsy, which is costly, invasive...

The effects of A2B receptor modulators on vascular endothelial growth factor and nitric oxide axis in chronic cyclosporine nephropathy.

Journal of pharmacology & pharmacotherapeutics

Patel L, Thaker A.
PMID: 26311998
J Pharmacol Pharmacother. 2015 Jul-Sep;6(3):147-53. doi: 10.4103/0976-500X.162014.

INTRODUCTION: To investigate the actions of adenosine A2B receptor modulators on VEGF and NO levels in CsA nephropathy.MATERIALS AND METHODS: Nephropathy was induced by administrating 25 mg/kg (s.c) of CsA for 5 weeks. The VEGF and NO levels were...

Does cyclosporine affect the duration of action of vecuronium in renal transplant recipients?.

Journal of anesthesia

Takita K, Goda Y, Kemmotsu O, Okuyama A, Ito T, Sakamoto H, Mashio H, Kawahigashi H.
PMID: 28921224
J Anesth. 1995 Sep;9(3):239-242. doi: 10.1007/BF02479871.

The duration of action of vecuronium was tested in 41 surgical patients to evaluate whether cyclosporine modulates the action of vecuronium. The patients were divided into three groups: 12 patients with normal renal function (group A); 14 renal transplant...

A Case of Psoriasis Vulgaris Aggravated with Atorvastatin, Aided by Concomitant Cyclosporine.

Indian journal of dermatology

Ardeshna KP, Someshwar S, Rohatgi S, Jerajani HR.
PMID: 28979024
Indian J Dermatol. 2017 Sep-Oct;62(5):537-538. doi: 10.4103/ijd.IJD_749_16.

No abstract available.

Serum levels of anti-CCP antibodies, anti-MCV antibodies and RF IgA in the follow-up of patients with rheumatoid arthritis treated with rituximab.

Auto- immunity highlights

Fabris M, De Vita S, Blasone N, Visentini D, Pezzarini E, Pontarini E, Fabro C, Quartuccio L, Mazzolini S, Curcio F, Tonutti E.
PMID: 26000112
Auto Immun Highlights. 2010 Nov 04;1(2):87-94. doi: 10.1007/s13317-010-0013-5. eCollection 2010 Nov.

Rheumatoid arthritis (RA) is characterized by the presence of circulating rheumatoid factor (RF) and anticitrullinated peptide antibodies (ACPA), which are positive in about 70-80% of patients. APCA have a higher specificity and therefore a higher diagnostic power than RF,...

Showing 1 to 12 of 2009 entries