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Effect of entecavir in the treatment of patients with hepatitis B virus-related compensated and decompensated cirrhosis.

Experimental and therapeutic medicine

Gai XD, Wu WF.
PMID: 29043000
Exp Ther Med. 2017 Oct;14(4):3908-3914. doi: 10.3892/etm.2017.4963. Epub 2017 Aug 18.

Chronic hepatitis B virus (CHB) infection is a burden on global healthcare and is associated with a higher risk of serious sequelae, including cirrhosis and hepatocellular carcinoma. The clinical application of entecavir as a treatment for CHB has produced...

DNA synthesis in a Chlorella-like alga following infection with the virus PBCV-1.

Virology

Van Etten JL, Burbank DE, Joshi J, Meints RH.
PMID: 18639814
Virology. 1984 Apr 30;134(2):443-9. doi: 10.1016/0042-6822(84)90311-8.

Infection of the unicellular, eukaryotic Chlorella-like alga NC64A by the large dsDNA virus, PBCV-1, resulted in a threefold increase in total DNA by 4 hr post infection. Viral infection rapidly inhibited host DNA synthesis which was followed by the...

Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report.

Viruses

Schewe K, Noah C, Sirma H, Schmiedel S, van Lunzen J, Rockstroh JK, Schildgen O.
PMID: 21994693
Viruses. 2010 Aug;2(8):1564-70. doi: 10.3390/v2081564. Epub 2010 Jul 29.

A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful...

Anti-Viral Evaluation of Sesquiterpene Coumarins from Ferula assa-foetida against HSV-1.

Iranian journal of pharmaceutical research : IJPR

Ghannadi A, Fattahian K, Shokoohinia Y, Behbahani M, Shahnoush A.
PMID: 25237347
Iran J Pharm Res. 2014;13(2):523-30.

Several complications attributed with Herpes virus related infections and the emergence of drug resistant viruses prompt scientists to search for new drugs. Several terpenoids and coumarins have shown anti HSV effects while no sesquiterpene coumarins have been previously tested...

Predictors for advanced liver fibrosis in chronic hepatitis B virus infection with persistently normal or mildly elevated alanine aminotransferase.

Experimental and therapeutic medicine

Wang D, Zhang P, Zhang M.
PMID: 29285064
Exp Ther Med. 2017 Dec;14(6):5363-5370. doi: 10.3892/etm.2017.5219. Epub 2017 Sep 29.

The aim of the present study was to evaluate the predictors for advanced liver fibrosis in patients with chronic hepatitis B virus (HBV) infection with persistently normal alanine aminotransferase (PNALT), or persistently or intermittently mildly elevated ALT (PIEALT). A...

Metagenomic data of DNA viruses of poultry affected with respiratory tract infection.

Data in brief

Sajnani MR, Sudarsanam D, Pandit RJ, Oza T, Hinsu AT, Jakhesara SJ, Solosanc S, Joshi CG, Bhatt VD.
PMID: 29541659
Data Brief. 2017 Nov 13;16:157-160. doi: 10.1016/j.dib.2017.11.033. eCollection 2018 Feb.

The incidence and severity of respiratory diseases in commercial broiler chicken flocks have increased recently in India because of intensification of the broiler industry. Viral population are predominant in respiratory tract infections and they pose continuous economic burden to...

Effect of electrochemotherapy on human herpesvirus 8 kinetics in classic Kaposi sarcoma.

Infectious agents and cancer

Starita N, Di Monta G, Cerasuolo A, Marone U, Anniciello AM, Botti G, Buonaguro L, Buonaguro FM, Tornesello ML.
PMID: 28649271
Infect Agent Cancer. 2017 Jun 19;12:35. doi: 10.1186/s13027-017-0147-4. eCollection 2017.

BACKGROUND: Electrochemotherapy (ECT) has shown to be an effective treatment for cutaneous and subcutaneous Kaposi sarcoma (KS) lesions. However, no study has investigated the impact of ECT treatment on the kinetics of human herpesvirus type 8 (HHV8), which is...

Application of HDR-CRISPR/Cas9 and Erythrocyte Binding for Rapid Generation of Recombinant Turkey Herpesvirus-Vectored Avian Influenza Virus Vaccines.

Vaccines

Chang P, Ameen F, Sealy JE, Sadeyen JR, Bhat S, Li Y, Iqbal M.
PMID: 31766655
Vaccines (Basel). 2019 Nov 22;7(4). doi: 10.3390/vaccines7040192.

Avian influenza viruses (AIVs) are highly contagious and have caused huge economical loss to the poultry industry. AIV vaccines remain one of the most effective methods of controlling this disease. Turkey herpesvirus (HVT) is a commonly used live attenuated...

Quantification of HIV-2 DNA in Whole Blood.

Bio-protocol

Szojka Z, Karlson S, Jansson M, Medstrand P.
PMID: 33654905
Bio Protoc. 2019 Oct 20;9(20):e3404. doi: 10.21769/BioProtoc.3404. eCollection 2019 Oct 20.

Time to AIDS infection is longer with HIV-2, compared to HIV-1, but without antiretroviral therapy both infections will cause AIDS-related mortality. In HIV-2 infection, monitoring of antiretroviral treatment (ART) efficacy is challenging since a large proportion of HIV-2-infected individuals...

Virome characterization in serum of healthy show pigs raised in Oklahoma demonstrated great diversity of ssDNA viruses.

Virology

Paim WP, Maggioli MF, Weber MN, Rezabek G, Narayanan S, Ramachandran A, Canal CW, Bauermann FV.
PMID: 33550118
Virology. 2021 Apr;556:87-95. doi: 10.1016/j.virol.2021.01.006. Epub 2021 Jan 30.

In the United States, show pigs are raised to compete in agricultural events. These animals are usually raised in small herds with extensive human, domestic, and wild animal contact. Therefore, pathogen monitoring in this animal category is critical for...

MicroRNA-138 Regulates T-Cell Function by Targeting PD-1 in Patients with Hepatitis B Virus-Related Liver Diseases.

Laboratory medicine

Liu W, Zheng X, Wang J, He Q, Li J, Zhang Z, Liu H.
PMID: 33410459
Lab Med. 2021 Sep 01;52(5):439-451. doi: 10.1093/labmed/lmaa110.

OBJECTIVE: T-cell exhaustion in hepatitis B virus (HBV) infection, which results from upregulation of programmed cell death-1 (PD-1), leads to persistent HBV infection and related disease progression. Therefore, agents targeting PD-1 may prove beneficial in the treatment of this...

A variety of highly divergent eukaryotic ssDNA viruses in sera of pigs.

The Journal of general virology

Tochetto C, Cibulski SP, Muterle Varela AP, Cerva C, Alves de Lima D, Fumaco Teixeira T, Quoos Mayer F, Roehe PM.
PMID: 34928204
J Gen Virol. 2021 Dec;102(12). doi: 10.1099/jgv.0.001706.

Over the last decade, viral metagenomics has been established as a non-targeted approach for identifying viruses in stock animals, including pigs. This has led to the identification of a vast diversity of small circular ssDNA viruses. The present study...

Showing 1 to 12 of 75 entries