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Evaluation of cyclooxygenase-1 and cyclooxygenase-2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma.

Veterinary and comparative oncology

Sorenmo KU, Goldschmidt MH, Shofer FS, Goldkamp C, Ferracone J.
PMID: 19379307
Vet Comp Oncol. 2004 Mar;2(1):13-23. doi: 10.1111/j.1476-5810.2004.00035.x.

Prostatic carcinoma occurs primarily in older castrated male dogs and is typically a fatal disease (most dogs die within few months after the initial diagnosis). Surgery, i.e., total prostatectomy, or radiation therapy is often not pursued due to risks...

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Sorenmo KU, Goldschmidt MH, Shofer FS, et al. Evaluation of cyclooxygenase-1 and cyclooxygenase-2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma. Vet Comp Oncol. 2004;2(1):13-23doi: 10.1111/j.1476-5810.2004.00035.x.
Sorenmo, K. U., Goldschmidt, M. H., Shofer, F. S., Goldkamp, C., & Ferracone, J. (2004). Evaluation of cyclooxygenase-1 and cyclooxygenase-2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma. Veterinary and comparative oncology, 2(1), 13-23. https://doi.org/10.1111/j.1476-5810.2004.00035.x
Sorenmo, K U, et al. "Evaluation of cyclooxygenase-1 and cyclooxygenase-2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma." Veterinary and comparative oncology vol. 2,1 (2004): 13-23. doi: https://doi.org/10.1111/j.1476-5810.2004.00035.x
Sorenmo KU, Goldschmidt MH, Shofer FS, Goldkamp C, Ferracone J. Evaluation of cyclooxygenase-1 and cyclooxygenase-2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma. Vet Comp Oncol. 2004 Mar;2(1):13-23. doi: 10.1111/j.1476-5810.2004.00035.x. PMID: 19379307.
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Feprazone Ameliorates TNF-α-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway.

ACS omega

Xiong X, Liu L, Xu F, Wu X, Yin Z, Dong Y, Qian P.
PMID: 33778274
ACS Omega. 2021 Mar 12;6(11):7638-7645. doi: 10.1021/acsomega.0c06212. eCollection 2021 Mar 23.

No abstract available.

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Xiong X, Liu L, Xu F, et al. Feprazone Ameliorates TNF-α-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway. ACS Omega. 2021;6(11):7638-7645doi: 10.1021/acsomega.0c06212.
Xiong, X., Liu, L., Xu, F., Wu, X., Yin, Z., Dong, Y., & Qian, P. (2021). Feprazone Ameliorates TNF-α-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway. ACS omega, 6(11), 7638-7645. https://doi.org/10.1021/acsomega.0c06212
Xiong, Xiaoyang, et al. "Feprazone Ameliorates TNF-α-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway." ACS omega vol. 6,11 (2021): 7638-7645. doi: https://doi.org/10.1021/acsomega.0c06212
Xiong X, Liu L, Xu F, Wu X, Yin Z, Dong Y, Qian P. Feprazone Ameliorates TNF-α-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway. ACS Omega. 2021 Mar 12;6(11):7638-7645. doi: 10.1021/acsomega.0c06212. eCollection 2021 Mar 23. PMID: 33778274; PMCID: PMC7992146.
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Feprazone Displays Antiadipogenesis and Antiobesity Capacities in in Vitro 3 T3-L1 Cells and in Vivo Mice.

ACS omega

Che L, Ren B, Jia Y, Dong Y, Wang Y, Shan J, Wang Y.
PMID: 33748580
ACS Omega. 2021 Mar 07;6(10):6674-6680. doi: 10.1021/acsomega.0c05470. eCollection 2021 Mar 16.

BACKGROUND AND PURPOSE: Excessive lipid accumulation in adipose tissues and deregulation of adipogenesis-induced obesity affect millions of people worldwide. Feprazone, a nonsteroidal anti-inflammatory drug, has a wide clinical use. However, it is unknown whether Feprazone possesses an antiadipogenic ability....

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Che L, Ren B, Jia Y, et al. Feprazone Displays Antiadipogenesis and Antiobesity Capacities in in Vitro 3 T3-L1 Cells and in Vivo Mice. ACS Omega. 2021;6(10):6674-6680doi: 10.1021/acsomega.0c05470.
Che, L., Ren, B., Jia, Y., Dong, Y., Wang, Y., Shan, J., & Wang, Y. (2021). Feprazone Displays Antiadipogenesis and Antiobesity Capacities in in Vitro 3 T3-L1 Cells and in Vivo Mice. ACS omega, 6(10), 6674-6680. https://doi.org/10.1021/acsomega.0c05470
Che, Liqun, et al. "Feprazone Displays Antiadipogenesis and Antiobesity Capacities in in Vitro 3 T3-L1 Cells and in Vivo Mice." ACS omega vol. 6,10 (2021): 6674-6680. doi: https://doi.org/10.1021/acsomega.0c05470
Che L, Ren B, Jia Y, Dong Y, Wang Y, Shan J, Wang Y. Feprazone Displays Antiadipogenesis and Antiobesity Capacities in in Vitro 3 T3-L1 Cells and in Vivo Mice. ACS Omega. 2021 Mar 07;6(10):6674-6680. doi: 10.1021/acsomega.0c05470. eCollection 2021 Mar 16. PMID: 33748580; PMCID: PMC7970497.
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The Potential Emergence of "Education as Mental Health Therapy" as a Feasible Form of Teacher-Delivered Child Mental Health Care in a Low and Middle Income Country: A Mixed Methods Pragmatic Pilot Study.

Frontiers in psychiatry

Cruz CM, Giri P, Vanderburg JL, Ferrarone P, Bhattarai S, Giardina AA, Gaynes BN, Hampanda K, Lamb MM, Matergia M.
PMID: 34975588
Front Psychiatry. 2021 Dec 16;12:790536. doi: 10.3389/fpsyt.2021.790536. eCollection 2021.

No abstract available.

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Cruz CM, Giri P, Vanderburg JL, et al. The Potential Emergence of "Education as Mental Health Therapy" as a Feasible Form of Teacher-Delivered Child Mental Health Care in a Low and Middle Income Country: A Mixed Methods Pragmatic Pilot Study. Front Psychiatry. 2021;12:790536doi: 10.3389/fpsyt.2021.790536.
Cruz, C. M., Giri, P., Vanderburg, J. L., Ferrarone, P., Bhattarai, S., Giardina, A. A., Gaynes, B. N., Hampanda, K., Lamb, M. M., & Matergia, M. (2021). The Potential Emergence of "Education as Mental Health Therapy" as a Feasible Form of Teacher-Delivered Child Mental Health Care in a Low and Middle Income Country: A Mixed Methods Pragmatic Pilot Study. Frontiers in psychiatry, 12790536. https://doi.org/10.3389/fpsyt.2021.790536
Cruz, Christina M, et al. "The Potential Emergence of "Education as Mental Health Therapy" as a Feasible Form of Teacher-Delivered Child Mental Health Care in a Low and Middle Income Country: A Mixed Methods Pragmatic Pilot Study." Frontiers in psychiatry vol. 12 (2021): 790536. doi: https://doi.org/10.3389/fpsyt.2021.790536
Cruz CM, Giri P, Vanderburg JL, Ferrarone P, Bhattarai S, Giardina AA, Gaynes BN, Hampanda K, Lamb MM, Matergia M. The Potential Emergence of "Education as Mental Health Therapy" as a Feasible Form of Teacher-Delivered Child Mental Health Care in a Low and Middle Income Country: A Mixed Methods Pragmatic Pilot Study. Front Psychiatry. 2021 Dec 16;12:790536. doi: 10.3389/fpsyt.2021.790536. eCollection 2021. PMID: 34975588; PMCID: PMC8717545.
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Perceptions, attitudes, and knowledge of teachers serving as mental health lay counselors in a low and middle income country: a mixed methods pragmatic pilot study.

International journal of mental health systems

Cruz CM, Lamb MM, Giri P, Vanderburg J, Ferrarone P, Bhattarai S, Giardina AA, Hampanda K, Gaynes BN, Matergia M.
PMID: 33926487
Int J Ment Health Syst. 2021 Apr 29;15(1):40. doi: 10.1186/s13033-021-00453-3.

BACKGROUND: Low and middle-income countries (LMICs) lack trained child mental health professionals. While teachers' child development experience potentially positions them to fill the gap as lay mental health counselors, they have rarely delivered indicated child mental health care in...

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Cruz CM, Lamb MM, Giri P, et al. Perceptions, attitudes, and knowledge of teachers serving as mental health lay counselors in a low and middle income country: a mixed methods pragmatic pilot study. Int J Ment Health Syst. 2021;15(1):40doi: 10.1186/s13033-021-00453-3.
Cruz, C. M., Lamb, M. M., Giri, P., Vanderburg, J., Ferrarone, P., Bhattarai, S., Giardina, A. A., Hampanda, K., Gaynes, B. N., & Matergia, M. (2021). Perceptions, attitudes, and knowledge of teachers serving as mental health lay counselors in a low and middle income country: a mixed methods pragmatic pilot study. International journal of mental health systems, 15(1), 40. https://doi.org/10.1186/s13033-021-00453-3
Cruz, Christina M, et al. "Perceptions, attitudes, and knowledge of teachers serving as mental health lay counselors in a low and middle income country: a mixed methods pragmatic pilot study." International journal of mental health systems vol. 15,1 (2021): 40. doi: https://doi.org/10.1186/s13033-021-00453-3
Cruz CM, Lamb MM, Giri P, Vanderburg J, Ferrarone P, Bhattarai S, Giardina AA, Hampanda K, Gaynes BN, Matergia M. Perceptions, attitudes, and knowledge of teachers serving as mental health lay counselors in a low and middle income country: a mixed methods pragmatic pilot study. Int J Ment Health Syst. 2021 Apr 29;15(1):40. doi: 10.1186/s13033-021-00453-3. PMID: 33926487; PMCID: PMC8082764.
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Feprazone Mitigates IL-1β-Induced Cellular Senescence in Chondrocytes.

ACS omega

Huang Z, Lan J, Gao X.
PMID: 33869924
ACS Omega. 2021 Mar 31;6(14):9442-9448. doi: 10.1021/acsomega.0c06066. eCollection 2021 Apr 13.

The proinflammatory cytokine interleukin-1 β (IL-1β)-mediated cellular senescence in chondrocytes is involved in the development and pathological progression of osteoarthritis (OA). Feprazone, a nonsteroidal anti-inflammatory drug (NSAID) and a cyclooxygenase (COX) inhibitor, is widely used in clinics. This study...

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Huang Z, Lan J, Gao X. Feprazone Mitigates IL-1β-Induced Cellular Senescence in Chondrocytes. ACS Omega. 2021;6(14):9442-9448doi: 10.1021/acsomega.0c06066.
Huang, Z., Lan, J., & Gao, X. (2021). Feprazone Mitigates IL-1β-Induced Cellular Senescence in Chondrocytes. ACS omega, 6(14), 9442-9448. https://doi.org/10.1021/acsomega.0c06066
Huang, Zhusong, et al. "Feprazone Mitigates IL-1β-Induced Cellular Senescence in Chondrocytes." ACS omega vol. 6,14 (2021): 9442-9448. doi: https://doi.org/10.1021/acsomega.0c06066
Huang Z, Lan J, Gao X. Feprazone Mitigates IL-1β-Induced Cellular Senescence in Chondrocytes. ACS Omega. 2021 Mar 31;6(14):9442-9448. doi: 10.1021/acsomega.0c06066. eCollection 2021 Apr 13. PMID: 33869924; PMCID: PMC8047674.
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Static and dynamic coupled perturbed Hartree-Fock vibrational (hyper)polarizabilities of polyacetylene calculated by the finite field nuclear relaxation method.

The Journal of chemical physics

Lacivita V, Rérat M, Kirtman B, Orlando R, Ferrabone M, Dovesi R.
PMID: 22779633
J Chem Phys. 2012 Jul 07;137(1):014103. doi: 10.1063/1.4731266.

The vibrational contribution to static and dynamic (hyper)polarizability tensors of polyacetylene are theoretically investigated. Calculations were carried out by the finite field nuclear relaxation (FF-NR) method for periodic systems, newly implemented in the CRYSTAL code, using the coupled perturbed...

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Lacivita V, Rérat M, Kirtman B, et al. Static and dynamic coupled perturbed Hartree-Fock vibrational (hyper)polarizabilities of polyacetylene calculated by the finite field nuclear relaxation method. J Chem Phys. 2012;137(1):014103doi: 10.1063/1.4731266.
Lacivita, V., Rérat, M., Kirtman, B., Orlando, R., Ferrabone, M., & Dovesi, R. (2012). Static and dynamic coupled perturbed Hartree-Fock vibrational (hyper)polarizabilities of polyacetylene calculated by the finite field nuclear relaxation method. The Journal of chemical physics, 137(1), 014103. https://doi.org/10.1063/1.4731266
Lacivita, Valentina, et al. "Static and dynamic coupled perturbed Hartree-Fock vibrational (hyper)polarizabilities of polyacetylene calculated by the finite field nuclear relaxation method." The Journal of chemical physics vol. 137,1 (2012): 014103. doi: https://doi.org/10.1063/1.4731266
Lacivita V, Rérat M, Kirtman B, Orlando R, Ferrabone M, Dovesi R. Static and dynamic coupled perturbed Hartree-Fock vibrational (hyper)polarizabilities of polyacetylene calculated by the finite field nuclear relaxation method. J Chem Phys. 2012 Jul 07;137(1):014103. doi: 10.1063/1.4731266. PMID: 22779633.
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Anharmonic Vibrational States of Solids from DFT Calculations. Part II: Implementation of the VSCF and VCI Methods.

Journal of chemical theory and computation

Erba A, Maul J, Ferrabone M, Dovesi R, Rérat M, Carbonnière P.
PMID: 31038948
J Chem Theory Comput. 2019 Jun 11;15(6):3766-3777. doi: 10.1021/acs.jctc.9b00294. Epub 2019 May 28.

Two methods are implemented in the Crystal program for the calculation of anharmonic vibrational states of solids: the vibrational self-consistent field (VSCF) and the vibrational configuration-interaction (VCI). While the former is a mean-field approach, where each vibrational mode interacts...

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Erba A, Maul J, Ferrabone M, et al. Anharmonic Vibrational States of Solids from DFT Calculations. Part II: Implementation of the VSCF and VCI Methods. J Chem Theory Comput. 2019;15(6):3766-3777doi: 10.1021/acs.jctc.9b00294.
Erba, A., Maul, J., Ferrabone, M., Dovesi, R., Rérat, M., & Carbonnière, P. (2019). Anharmonic Vibrational States of Solids from DFT Calculations. Part II: Implementation of the VSCF and VCI Methods. Journal of chemical theory and computation, 15(6), 3766-3777. https://doi.org/10.1021/acs.jctc.9b00294
Erba, Alessandro, et al. "Anharmonic Vibrational States of Solids from DFT Calculations. Part II: Implementation of the VSCF and VCI Methods." Journal of chemical theory and computation vol. 15,6 (2019): 3766-3777. doi: https://doi.org/10.1021/acs.jctc.9b00294
Erba A, Maul J, Ferrabone M, Dovesi R, Rérat M, Carbonnière P. Anharmonic Vibrational States of Solids from DFT Calculations. Part II: Implementation of the VSCF and VCI Methods. J Chem Theory Comput. 2019 Jun 11;15(6):3766-3777. doi: 10.1021/acs.jctc.9b00294. Epub 2019 May 28. PMID: 31038948.
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GCN2 kinase activation by ATP-competitive kinase inhibitors.

Nature chemical biology

Tang CP, Clark O, Ferrarone JR, Campos C, Lalani AS, Chodera JD, Intlekofer AM, Elemento O, Mellinghoff IK.
PMID: 34949839
Nat Chem Biol. 2021 Dec 23; doi: 10.1038/s41589-021-00947-8. Epub 2021 Dec 23.

Small-molecule kinase inhibitors represent a major group of cancer therapeutics, but tumor responses are often incomplete. To identify pathways that modulate kinase inhibitor response, we conducted a genome-wide knockout (KO) screen in glioblastoma cells treated with the pan-ErbB inhibitor...

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Tang CP, Clark O, Ferrarone JR, et al. GCN2 kinase activation by ATP-competitive kinase inhibitors. Nat Chem Biol. 2021;doi: 10.1038/s41589-021-00947-8.
Tang, C. P., Clark, O., Ferrarone, J. R., Campos, C., Lalani, A. S., Chodera, J. D., Intlekofer, A. M., Elemento, O., & Mellinghoff, I. K. (2021). GCN2 kinase activation by ATP-competitive kinase inhibitors. Nature chemical biology, . https://doi.org/10.1038/s41589-021-00947-8
Tang, Colin P, et al. "GCN2 kinase activation by ATP-competitive kinase inhibitors." Nature chemical biology vol. (2021). doi: https://doi.org/10.1038/s41589-021-00947-8
Tang CP, Clark O, Ferrarone JR, Campos C, Lalani AS, Chodera JD, Intlekofer AM, Elemento O, Mellinghoff IK. GCN2 kinase activation by ATP-competitive kinase inhibitors. Nat Chem Biol. 2021 Dec 23; doi: 10.1038/s41589-021-00947-8. Epub 2021 Dec 23. PMID: 34949839.
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The micro gas-liquid chromatographic analysis of 4-(3',3'-dimethylallyl)-1,2-diphenylpyrazolidine-3,5-dione (feprazone) in human biosamples.

Journal of pharmaceutical and biomedical analysis

Berry DJ, Parke DV.
PMID: 16867395
J Pharm Biomed Anal. 1988;6(5):493-501. doi: 10.1016/0731-7085(88)80016-5.

A gas-liquid chromatographic method for the determination of feprazone in various biological matrixes, employing a choice of detector options, is described. After rapid, micro-scale extraction of the sample with n-butyl acetate at physiological pH, the solution was injected directly...

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Berry DJ, Parke DV. The micro gas-liquid chromatographic analysis of 4-(3',3'-dimethylallyl)-1,2-diphenylpyrazolidine-3,5-dione (feprazone) in human biosamples. J Pharm Biomed Anal. 1988;6(5):493-501doi: 10.1016/0731-7085(88)80016-5.
Berry, D. J., & Parke, D. V. (1988). The micro gas-liquid chromatographic analysis of 4-(3',3'-dimethylallyl)-1,2-diphenylpyrazolidine-3,5-dione (feprazone) in human biosamples. Journal of pharmaceutical and biomedical analysis, 6(5), 493-501. https://doi.org/10.1016/0731-7085(88)80016-5
Berry, D J, and Parke, D V. "The micro gas-liquid chromatographic analysis of 4-(3',3'-dimethylallyl)-1,2-diphenylpyrazolidine-3,5-dione (feprazone) in human biosamples." Journal of pharmaceutical and biomedical analysis vol. 6,5 (1988): 493-501. doi: https://doi.org/10.1016/0731-7085(88)80016-5
Berry DJ, Parke DV. The micro gas-liquid chromatographic analysis of 4-(3',3'-dimethylallyl)-1,2-diphenylpyrazolidine-3,5-dione (feprazone) in human biosamples. J Pharm Biomed Anal. 1988;6(5):493-501. doi: 10.1016/0731-7085(88)80016-5. PMID: 16867395.
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Immunohistochemical characterization of canine prostatic carcinoma and correlation with castration status and castration time.

Veterinary and comparative oncology

Sorenmo KU, Goldschmidt M, Shofer F, Goldkamp C, Ferracone J.
PMID: 19379330
Vet Comp Oncol. 2003 Mar;1(1):48-56. doi: 10.1046/j.1476-5829.2003.00007.x.

The purpose of this study was to characterize canine prostate cancer using immunohistochemical staining specific for acinar and urothelial/ductal tissue and correlate these results with the dogs' castration status/castration time. Seventy dogs with prostate cancer were included, 71% were...

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Sorenmo KU, Goldschmidt M, Shofer F, et al. Immunohistochemical characterization of canine prostatic carcinoma and correlation with castration status and castration time. Vet Comp Oncol. 2003;1(1):48-56doi: 10.1046/j.1476-5829.2003.00007.x.
Sorenmo, K. U., Goldschmidt, M., Shofer, F., Goldkamp, C., & Ferracone, J. (2003). Immunohistochemical characterization of canine prostatic carcinoma and correlation with castration status and castration time. Veterinary and comparative oncology, 1(1), 48-56. https://doi.org/10.1046/j.1476-5829.2003.00007.x
Sorenmo, K U, et al. "Immunohistochemical characterization of canine prostatic carcinoma and correlation with castration status and castration time." Veterinary and comparative oncology vol. 1,1 (2003): 48-56. doi: https://doi.org/10.1046/j.1476-5829.2003.00007.x
Sorenmo KU, Goldschmidt M, Shofer F, Goldkamp C, Ferracone J. Immunohistochemical characterization of canine prostatic carcinoma and correlation with castration status and castration time. Vet Comp Oncol. 2003 Mar;1(1):48-56. doi: 10.1046/j.1476-5829.2003.00007.x. PMID: 19379330.
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On the use of symmetry in configurational analysis for the simulation of disordered solids.

Journal of physics. Condensed matter : an Institute of Physics journal

Mustapha S, D'Arco P, De La Pierre M, Noël Y, Ferrabone M, Dovesi R.
PMID: 23388579
J Phys Condens Matter. 2013 Mar 13;25(10):105401. doi: 10.1088/0953-8984/25/10/105401. Epub 2013 Feb 06.

The starting point for a quantum mechanical investigation of disordered systems usually implies calculations on a limited subset of configurations, generated by defining either the composition of interest or a set of compositions ranging from one end member to...

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Mustapha S, D'Arco P, De La Pierre M, et al. On the use of symmetry in configurational analysis for the simulation of disordered solids. J Phys Condens Matter. 2013;25(10):105401doi: 10.1088/0953-8984/25/10/105401.
Mustapha, S., D'Arco, P., De La Pierre, M., Noël, Y., Ferrabone, M., & Dovesi, R. (2013). On the use of symmetry in configurational analysis for the simulation of disordered solids. Journal of physics. Condensed matter : an Institute of Physics journal, 25(10), 105401. https://doi.org/10.1088/0953-8984/25/10/105401
Mustapha, Sami, et al. "On the use of symmetry in configurational analysis for the simulation of disordered solids." Journal of physics. Condensed matter : an Institute of Physics journal vol. 25,10 (2013): 105401. doi: https://doi.org/10.1088/0953-8984/25/10/105401
Mustapha S, D'Arco P, De La Pierre M, Noël Y, Ferrabone M, Dovesi R. On the use of symmetry in configurational analysis for the simulation of disordered solids. J Phys Condens Matter. 2013 Mar 13;25(10):105401. doi: 10.1088/0953-8984/25/10/105401. Epub 2013 Feb 06. PMID: 23388579.
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