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Showing 1 to 12 of 34 entries
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SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer.

World journal of stem cells

Maiese K.
PMID: 25815111
World J Stem Cells. 2015 Mar 26;7(2):235-42. doi: 10.4252/wjsc.v7.i2.235.

Cardiovascular disease, nervous system disorders, and cancer in association with other diseases such as diabetes mellitus result in greater than sixty percent of the global annual deaths. These noncommunicable diseases also affect at least one-third of the population in...

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Maiese K. SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer. World J Stem Cells. 2015;7(2):235-42doi: 10.4252/wjsc.v7.i2.235.
Maiese, K. (2015). SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer. World journal of stem cells, 7(2), 235-42. https://doi.org/10.4252/wjsc.v7.i2.235
Maiese, Kenneth. "SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer." World journal of stem cells vol. 7,2 (2015): 235-42. doi: https://doi.org/10.4252/wjsc.v7.i2.235
Maiese K. SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer. World J Stem Cells. 2015 Mar 26;7(2):235-42. doi: 10.4252/wjsc.v7.i2.235. PMID: 25815111; PMCID: PMC4369483.
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Understanding the perspectives of forkhead transcription factors in delayed wound healing.

Journal of cell communication and signaling

Rajendran NK, Dhilip Kumar SS, Houreld NN, Abrahamse H.
PMID: 30088222
J Cell Commun Signal. 2019 Jun;13(2):151-162. doi: 10.1007/s12079-018-0484-0. Epub 2018 Aug 07.

Wound healing is a complex overlapping biological process that involves a sequence of events coordinated by various cells, proteins, growth factors, cytokines and signaling molecules. Recent evidence indicates that forkhead box O1 (FOXO1) transcription factors play an important role...

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Rajendran NK, Dhilip Kumar SS, Houreld NN, et al. Understanding the perspectives of forkhead transcription factors in delayed wound healing. J Cell Commun Signal. 2018;13(2):151-162doi: 10.1007/s12079-018-0484-0.
Rajendran, N. K., Dhilip Kumar, S. S., Houreld, N. N., & Abrahamse, H. (2019). Understanding the perspectives of forkhead transcription factors in delayed wound healing. Journal of cell communication and signaling, 13(2), 151-162. https://doi.org/10.1007/s12079-018-0484-0
Rajendran, Naresh Kumar, et al. "Understanding the perspectives of forkhead transcription factors in delayed wound healing." Journal of cell communication and signaling vol. 13,2 (2019): 151-162. doi: https://doi.org/10.1007/s12079-018-0484-0
Rajendran NK, Dhilip Kumar SS, Houreld NN, Abrahamse H. Understanding the perspectives of forkhead transcription factors in delayed wound healing. J Cell Commun Signal. 2019 Jun;13(2):151-162. doi: 10.1007/s12079-018-0484-0. Epub 2018 Aug 07. PMID: 30088222; PMCID: PMC6498300.
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Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.

Protein & cell

Xia YK, Zeng YR, Zhang ML, Liu P, Liu F, Zhang H, He CX, Sun YP, Zhang JY, Zhang C, Song L, Ding C, Tang YJ, Yang Z, Yang C, Wang P, Guan KL, Xiong Y, Ye D.
PMID: 32683582
Protein Cell. 2021 Jul;12(7):557-577. doi: 10.1007/s13238-020-00754-2. Epub 2020 Jul 18.

Additional sex combs-like 1 (ASXL1) interacts with BRCA1-associated protein 1 (BAP1) deubiquitinase to oppose the polycomb repressive complex 1 (PRC1)-mediated histone H2A ubiquitylation. Germline BAP1 mutations are found in a spectrum of human malignancies, while ASXL1 mutations recurrently occur...

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Xia YK, Zeng YR, Zhang ML, et al. Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein Cell. 2020;12(7):557-577doi: 10.1007/s13238-020-00754-2.
Xia, Y. K., Zeng, Y. R., Zhang, M. L., Liu, P., Liu, F., Zhang, H., He, C. X., Sun, Y. P., Zhang, J. Y., Zhang, C., Song, L., Ding, C., Tang, Y. J., Yang, Z., Yang, C., Wang, P., Guan, K. L., Xiong, Y., & Ye, D. (2021). Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein & cell, 12(7), 557-577. https://doi.org/10.1007/s13238-020-00754-2
Xia, Yu-Kun, et al. "Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network." Protein & cell vol. 12,7 (2021): 557-577. doi: https://doi.org/10.1007/s13238-020-00754-2
Xia YK, Zeng YR, Zhang ML, Liu P, Liu F, Zhang H, He CX, Sun YP, Zhang JY, Zhang C, Song L, Ding C, Tang YJ, Yang Z, Yang C, Wang P, Guan KL, Xiong Y, Ye D. Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein Cell. 2021 Jul;12(7):557-577. doi: 10.1007/s13238-020-00754-2. Epub 2020 Jul 18. PMID: 32683582; PMCID: PMC8225741.
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FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast Conversion.

Journal of cellular signaling

Wright WE, Li C, Zheng CX, Tucker HO.
PMID: 33554216
J Cell Signal. 2021;2(1):9-26.

Forkhead transcription factors (TFs) often dimerize outside their extensive family, whereas bHLH transcription factors typically dimerize with E12/E47. Based on structural similarities, we predicted that a member of the former, Forkhead Box P1 (FOXP1), might heterodimerize with a member...

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Wright WE, Li C, Zheng CX, et al. FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast Conversion. J Cell Signal. 2021;2(1):9-26
Wright, W. E., Li, C., Zheng, C. X., & Tucker, H. O. (2021). FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast Conversion. Journal of cellular signaling, 2(1), 9-26.
Wright, Woodring E, et al. "FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast Conversion." Journal of cellular signaling vol. 2,1 (2021): 9-26.
Wright WE, Li C, Zheng CX, Tucker HO. FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast Conversion. J Cell Signal. 2021;2(1):9-26. PMID: 33554216; PMCID: PMC7861563.
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Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell.

Journal of molecular medicine (Berlin, Germany)

Takahashi A, Yousif A, Hong L, Chefetz I.
PMID: 33641066
J Mol Med (Berl). 2021 May;99(5):637-650. doi: 10.1007/s00109-021-02055-5. Epub 2021 Feb 27.

Primary ovarian insufficiency (POI) is defined as a reduction in ovarian function before the expected age of menopause. POI is known to increase the risk of cardiovascular disorders, osteoporosis, cognitive decline, and mood disorders, resulting in a reduced quality...

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Takahashi A, Yousif A, Hong L, et al. Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell. J Mol Med (Berl). 2021;99(5):637-650doi: 10.1007/s00109-021-02055-5.
Takahashi, A., Yousif, A., Hong, L., & Chefetz, I. (2021). Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell. Journal of molecular medicine (Berlin, Germany), 99(5), 637-650. https://doi.org/10.1007/s00109-021-02055-5
Takahashi, Akimasa, et al. "Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell." Journal of molecular medicine (Berlin, Germany) vol. 99,5 (2021): 637-650. doi: https://doi.org/10.1007/s00109-021-02055-5
Takahashi A, Yousif A, Hong L, Chefetz I. Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell. J Mol Med (Berl). 2021 May;99(5):637-650. doi: 10.1007/s00109-021-02055-5. Epub 2021 Feb 27. PMID: 33641066.
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Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations.

Nucleic acids research

Dai S, Qu L, Li J, Chen Y.
PMID: 34551426
Nucleic Acids Res. 2021 Oct 11;49(18):10235-10249. doi: 10.1093/nar/gkab807.

Forkhead box (FOX) proteins are an evolutionarily conserved family of transcription factors that play numerous regulatory roles in eukaryotes during developmental and adult life. Dysfunction of FOX proteins has been implicated in a variety of human diseases, including cancer,...

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Dai S, Qu L, Li J, et al. Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations. Nucleic Acids Res. 2021;49(18):10235-10249doi: 10.1093/nar/gkab807.
Dai, S., Qu, L., Li, J., & Chen, Y. (2021). Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations. Nucleic acids research, 49(18), 10235-10249. https://doi.org/10.1093/nar/gkab807
Dai, Shuyan, et al. "Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations." Nucleic acids research vol. 49,18 (2021): 10235-10249. doi: https://doi.org/10.1093/nar/gkab807
Dai S, Qu L, Li J, Chen Y. Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations. Nucleic Acids Res. 2021 Oct 11;49(18):10235-10249. doi: 10.1093/nar/gkab807. PMID: 34551426; PMCID: PMC8501956.
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Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy.

JACC. Basic to translational science

Wang B, Wang ZM, Ji JL, Gan W, Zhang A, Shi HJ, Wang H, Lv L, Li Z, Tang T, Du J, Wang XH, Liu BC.
PMID: 32140622
JACC Basic Transl Sci. 2020 Jan 15;5(2):148-166. doi: 10.1016/j.jacbts.2019.10.011. eCollection 2020 Feb.

miR-155 was synthesized and loaded into exosomes in increased infiltration of macrophages in a uremic heart. The released exosomal fusion with the plasma membrane leads to the release of miR-155 into the cytosol and translational repression of forkhead transcription...

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Wang B, Wang ZM, Ji JL, et al. Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy. JACC Basic Transl Sci. 2020;5(2):148-166doi: 10.1016/j.jacbts.2019.10.011.
Wang, B., Wang, Z. M., Ji, J. L., Gan, W., Zhang, A., Shi, H. J., Wang, H., Lv, L., Li, Z., Tang, T., Du, J., Wang, X. H., & Liu, B. C. (2020). Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy. JACC. Basic to translational science, 5(2), 148-166. https://doi.org/10.1016/j.jacbts.2019.10.011
Wang, Bin, et al. "Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy." JACC. Basic to translational science vol. 5,2 (2020): 148-166. doi: https://doi.org/10.1016/j.jacbts.2019.10.011
Wang B, Wang ZM, Ji JL, Gan W, Zhang A, Shi HJ, Wang H, Lv L, Li Z, Tang T, Du J, Wang XH, Liu BC. Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy. JACC Basic Transl Sci. 2020 Jan 15;5(2):148-166. doi: 10.1016/j.jacbts.2019.10.011. eCollection 2020 Feb. PMID: 32140622; PMCID: PMC7046511.
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The role of SIRT1 in tumorigenesis.

North American journal of medicine & science

Li K, Luo J.
PMID: 22180829
N Am J Med Sci (Boston). 2011;4(2):104-106. doi: 10.7156/v4i2p104.

NAD-dependent Class III histone deacetylase SIRT1 is a multiple functional protein and has been demonstrated critically involved in stress response, cellular metabolism and aging through deacetylating variety of substrates including p53, forkhead transcription factors, PGC-1α, NF-κB, Ku70 and histones....

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Li K, Luo J. The role of SIRT1 in tumorigenesis. N Am J Med Sci (Boston). 2011;4(2):104-106doi: 10.7156/v4i2p104.
Li, K., & Luo, J. (2011). The role of SIRT1 in tumorigenesis. North American journal of medicine & science, 4(2), 104-106. https://doi.org/10.7156/v4i2p104
Li, Kai, and Luo, Jianyuan. "The role of SIRT1 in tumorigenesis." North American journal of medicine & science vol. 4,2 (2011): 104-106. doi: https://doi.org/10.7156/v4i2p104
Li K, Luo J. The role of SIRT1 in tumorigenesis. N Am J Med Sci (Boston). 2011;4(2):104-106. doi: 10.7156/v4i2p104. PMID: 22180829; PMCID: PMC3237400.
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Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression.

Frontiers in physiology

Baehr LM, Tunzi M, Bodine SC.
PMID: 24600408
Front Physiol. 2014 Feb 21;5:69. doi: 10.3389/fphys.2014.00069. eCollection 2014.

The regulation of skeletal muscle mass depends on the balance between protein synthesis and degradation. The role of protein degradation and in particular, the ubiquitin proteasome system, and increased expression of the E3 ubiquitin ligases, MuRF1 and MAFbx/atrogin-1, in...

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Baehr LM, Tunzi M, Bodine SC. Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression. Front Physiol. 2014;5:69doi: 10.3389/fphys.2014.00069.
Baehr, L. M., Tunzi, M., & Bodine, S. C. (2014). Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression. Frontiers in physiology, 569. https://doi.org/10.3389/fphys.2014.00069
Baehr, Leslie M, et al. "Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression." Frontiers in physiology vol. 5 (2014): 69. doi: https://doi.org/10.3389/fphys.2014.00069
Baehr LM, Tunzi M, Bodine SC. Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression. Front Physiol. 2014 Feb 21;5:69. doi: 10.3389/fphys.2014.00069. eCollection 2014. PMID: 24600408; PMCID: PMC3930915.
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Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations.

Nucleic acids research

Dai S, Qu L, Li J, Chen Y.
PMID: 34551426
Nucleic Acids Res. 2021 Oct 11;49(18):10235-10249. doi: 10.1093/nar/gkab807.

Forkhead box (FOX) proteins are an evolutionarily conserved family of transcription factors that play numerous regulatory roles in eukaryotes during developmental and adult life. Dysfunction of FOX proteins has been implicated in a variety of human diseases, including cancer,...

Cite
Dai S, Qu L, Li J, et al. Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations. Nucleic Acids Res. 2021;49(18):10235-10249doi: 10.1093/nar/gkab807.
Dai, S., Qu, L., Li, J., & Chen, Y. (2021). Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations. Nucleic acids research, 49(18), 10235-10249. https://doi.org/10.1093/nar/gkab807
Dai, Shuyan, et al. "Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations." Nucleic acids research vol. 49,18 (2021): 10235-10249. doi: https://doi.org/10.1093/nar/gkab807
Dai S, Qu L, Li J, Chen Y. Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations. Nucleic Acids Res. 2021 Oct 11;49(18):10235-10249. doi: 10.1093/nar/gkab807. PMID: 34551426; PMCID: PMC8501956.
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Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-year Prospective Longitudinal Cohort Study.

The journals of gerontology. Series A, Biological sciences and medical sciences

Ji JS, Liu L, Shu C, Yan LL, Zeng Y.
PMID: 34928346
J Gerontol A Biol Sci Med Sci. 2021 Dec 20; doi: 10.1093/gerona/glab378. Epub 2021 Dec 20.

SIRT1 and FOXO3 are both associated with longevity. Molecular biology research in many organisms (yeast, nematode worm Caenorhabditis elegans, and mice mammalian models) shows SIRT1 acts on the FOXO family of forkhead transcription factors to respond to oxidative stress...

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Ji JS, Liu L, Shu C, et al. Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-year Prospective Longitudinal Cohort Study. J Gerontol A Biol Sci Med Sci. 2021;doi: 10.1093/gerona/glab378.
Ji, J. S., Liu, L., Shu, C., Yan, L. L., & Zeng, Y. (2021). Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-year Prospective Longitudinal Cohort Study. The journals of gerontology. Series A, Biological sciences and medical sciences, . https://doi.org/10.1093/gerona/glab378
Ji, John S, et al. "Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-year Prospective Longitudinal Cohort Study." The journals of gerontology. Series A, Biological sciences and medical sciences vol. (2021). doi: https://doi.org/10.1093/gerona/glab378
Ji JS, Liu L, Shu C, Yan LL, Zeng Y. Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-year Prospective Longitudinal Cohort Study. J Gerontol A Biol Sci Med Sci. 2021 Dec 20; doi: 10.1093/gerona/glab378. Epub 2021 Dec 20. PMID: 34928346.
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Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast.

NPJ systems biology and applications

Barberis M.
PMID: 34903735
NPJ Syst Biol Appl. 2021 Dec 13;7(1):48. doi: 10.1038/s41540-021-00201-w.

Networks of interacting molecules organize topology, amount, and timing of biological functions. Systems biology concepts required to pin down 'network motifs' or 'design principles' for time-dependent processes have been developed for the cell division cycle, through integration of predictive...

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Barberis M. Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast. NPJ Syst Biol Appl. 2021;7(1):48doi: 10.1038/s41540-021-00201-w.
Barberis, M. (2021). Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast. NPJ systems biology and applications, 7(1), 48. https://doi.org/10.1038/s41540-021-00201-w
Barberis, Matteo. "Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast." NPJ systems biology and applications vol. 7,1 (2021): 48. doi: https://doi.org/10.1038/s41540-021-00201-w
Barberis M. Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast. NPJ Syst Biol Appl. 2021 Dec 13;7(1):48. doi: 10.1038/s41540-021-00201-w. PMID: 34903735.
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Showing 1 to 12 of 34 entries