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Molecular Mechanisms and Clinical Impact of Acquired and Intrinsic Fosfomycin Resistance.

Antibiotics (Basel, Switzerland)

Castañeda-García A, Blázquez J, Rodríguez-Rojas A.
PMID: 27029300
Antibiotics (Basel). 2013 Apr 16;2(2):217-36. doi: 10.3390/antibiotics2020217.

Bacterial infections caused by antibiotic-resistant isolates have become a major health problem in recent years, since they are very difficult to treat, leading to an increase in morbidity and mortality. Fosfomycin is a broad-spectrum bactericidal antibiotic that inhibits cell...

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Castañeda-García A, Blázquez J, Rodríguez-Rojas A. Molecular Mechanisms and Clinical Impact of Acquired and Intrinsic Fosfomycin Resistance. Antibiotics (Basel). 2013;2(2):217-36doi: 10.3390/antibiotics2020217.
Castañeda-García, A., Blázquez, J., & Rodríguez-Rojas, A. (2013). Molecular Mechanisms and Clinical Impact of Acquired and Intrinsic Fosfomycin Resistance. Antibiotics (Basel, Switzerland), 2(2), 217-36. https://doi.org/10.3390/antibiotics2020217
Castañeda-García, Alfredo, et al. "Molecular Mechanisms and Clinical Impact of Acquired and Intrinsic Fosfomycin Resistance." Antibiotics (Basel, Switzerland) vol. 2,2 (2013): 217-36. doi: https://doi.org/10.3390/antibiotics2020217
Castañeda-García A, Blázquez J, Rodríguez-Rojas A. Molecular Mechanisms and Clinical Impact of Acquired and Intrinsic Fosfomycin Resistance. Antibiotics (Basel). 2013 Apr 16;2(2):217-36. doi: 10.3390/antibiotics2020217. PMID: 27029300; PMCID: PMC4790336.
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Carriage of multidrug-resistant organisms in a tertiary university hospital in Albania-a point prevalence survey.

Antimicrobial resistance and infection control

Parascandalo FA, Zarb P, Tartari E, Lacej D, Bitincka S, Manastirliu O, Nika D, Borg MA.
PMID: 27499852
Antimicrob Resist Infect Control. 2016 Aug 05;5:29. doi: 10.1186/s13756-016-0128-1. eCollection 2016.

BACKGROUND: Antimicrobial resistance has been recognised as a serious global Public Health problem. Prevalence of Multiple-Drug-Resistant (MDR) organism carriage in Albania is largely unknown since no national surveillance system is in place and few publications are accessible in the...

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Parascandalo FA, Zarb P, Tartari E, et al. Carriage of multidrug-resistant organisms in a tertiary university hospital in Albania-a point prevalence survey. Antimicrob Resist Infect Control. 2016;5:29doi: 10.1186/s13756-016-0128-1.
Parascandalo, F. A., Zarb, P., Tartari, E., Lacej, D., Bitincka, S., Manastirliu, O., Nika, D., & Borg, M. A. (2016). Carriage of multidrug-resistant organisms in a tertiary university hospital in Albania-a point prevalence survey. Antimicrobial resistance and infection control, 529. https://doi.org/10.1186/s13756-016-0128-1
Parascandalo, Falzon A, et al. "Carriage of multidrug-resistant organisms in a tertiary university hospital in Albania-a point prevalence survey." Antimicrobial resistance and infection control vol. 5 (2016): 29. doi: https://doi.org/10.1186/s13756-016-0128-1
Parascandalo FA, Zarb P, Tartari E, Lacej D, Bitincka S, Manastirliu O, Nika D, Borg MA. Carriage of multidrug-resistant organisms in a tertiary university hospital in Albania-a point prevalence survey. Antimicrob Resist Infect Control. 2016 Aug 05;5:29. doi: 10.1186/s13756-016-0128-1. eCollection 2016. PMID: 27499852; PMCID: PMC4975909.
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A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library.

Frontiers in microbiology

Feng J, Shi W, Zhang S, Sullivan D, Auwaerter PG, Zhang Y.
PMID: 27242757
Front Microbiol. 2016 May 23;7:743. doi: 10.3389/fmicb.2016.00743. eCollection 2016.

Although currently recommended antibiotics for Lyme disease such as doxycycline or amoxicillin cure the majority of the patients, about 10-20% of patients treated for Lyme disease may experience lingering symptoms including fatigue, pain, or joint and muscle aches. Under...

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Feng J, Shi W, Zhang S, et al. A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Front Microbiol. 2016;7:743doi: 10.3389/fmicb.2016.00743.
Feng, J., Shi, W., Zhang, S., Sullivan, D., Auwaerter, P. G., & Zhang, Y. (2016). A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Frontiers in microbiology, 7743. https://doi.org/10.3389/fmicb.2016.00743
Feng, Jie, et al. "A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library." Frontiers in microbiology vol. 7 (2016): 743. doi: https://doi.org/10.3389/fmicb.2016.00743
Feng J, Shi W, Zhang S, Sullivan D, Auwaerter PG, Zhang Y. A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Front Microbiol. 2016 May 23;7:743. doi: 10.3389/fmicb.2016.00743. eCollection 2016. PMID: 27242757; PMCID: PMC4876775.
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Molecular Basis for Resistance Against Phosphonate Antibiotics and Herbicides.

MedChemComm

Chekan JR, Cogan DP, Nair SK.
PMID: 26811741
Medchemcomm. 2016 Jan 01;7(1):28-36. doi: 10.1039/C5MD00351B. Epub 2015 Oct 12.

Research in recent years have illuminated data on the mechanisms and targets of phosphonic acid antibiotics and herbicides, including fosfomycin, glyphosate, fosmidomycin and FR900098. Here we review the current state of knowledge of the structural and biochemical characterization of...

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Chekan JR, Cogan DP, Nair SK. Molecular Basis for Resistance Against Phosphonate Antibiotics and Herbicides. Medchemcomm. 2015;7(1):28-36doi: 10.1039/C5MD00351B.
Chekan, J. R., Cogan, D. P., & Nair, S. K. (2016). Molecular Basis for Resistance Against Phosphonate Antibiotics and Herbicides. MedChemComm, 7(1), 28-36. https://doi.org/10.1039/C5MD00351B
Chekan, Jonathan R, et al. "Molecular Basis for Resistance Against Phosphonate Antibiotics and Herbicides." MedChemComm vol. 7,1 (2016): 28-36. doi: https://doi.org/10.1039/C5MD00351B
Chekan JR, Cogan DP, Nair SK. Molecular Basis for Resistance Against Phosphonate Antibiotics and Herbicides. Medchemcomm. 2016 Jan 01;7(1):28-36. doi: 10.1039/C5MD00351B. Epub 2015 Oct 12. PMID: 26811741; PMCID: PMC4723106.
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Increasing antimicrobial resistance among uropathogens: Is fosfomycin the answer?.

Urology annals

Sultan A, Rizvi M, Khan F, Sami H, Shukla I, Khan HM.
PMID: 25657539
Urol Ann. 2015 Jan-Mar;7(1):26-30. doi: 10.4103/0974-7796.148585.

INTRODUCTION: Urinary tract infection (UTI) is one of the most common infectious diseases in clinical practice. The choice of antibiotics for the treatment of UTI is limited by the rising rates of antibiotic resistance. There is an urgent need...

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Sultan A, Rizvi M, Khan F, et al. Increasing antimicrobial resistance among uropathogens: Is fosfomycin the answer?. Urol Ann. 2015;7(1):26-30doi: 10.4103/0974-7796.148585.
Sultan, A., Rizvi, M., Khan, F., Sami, H., Shukla, I., & Khan, H. M. (2015). Increasing antimicrobial resistance among uropathogens: Is fosfomycin the answer?. Urology annals, 7(1), 26-30. https://doi.org/10.4103/0974-7796.148585
Sultan, Asfia, et al. "Increasing antimicrobial resistance among uropathogens: Is fosfomycin the answer?." Urology annals vol. 7,1 (2015): 26-30. doi: https://doi.org/10.4103/0974-7796.148585
Sultan A, Rizvi M, Khan F, Sami H, Shukla I, Khan HM. Increasing antimicrobial resistance among uropathogens: Is fosfomycin the answer?. Urol Ann. 2015 Jan-Mar;7(1):26-30. doi: 10.4103/0974-7796.148585. PMID: 25657539; PMCID: PMC4310112.
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A Patient Presenting with Cholangitis due to Stenotrophomonas Maltophilia and Pseudomonas Aeruginosa Successfully Treated with Intrabiliary Colistine.

Infectious disease reports

Pérez PN, Ramírez MA, Fernández JA, de Guevara LL.
PMID: 25002957
Infect Dis Rep. 2014 May 13;6(2):5147. doi: 10.4081/idr.2014.5147. eCollection 2014 May 13.

Anatomical barriers for antibiotic penetration can pose a particular challenge in the clinical setting. Stenotrophomonas maltophilia (SM) and Pseudomonas aeruginosa (PA) are two pathogens capable of developing multiple drug-resistance (MDR) mechanisms. We report the case of a 56-year-old female...

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Pérez PN, Ramírez MA, Fernández JA, et al. A Patient Presenting with Cholangitis due to Stenotrophomonas Maltophilia and Pseudomonas Aeruginosa Successfully Treated with Intrabiliary Colistine. Infect Dis Rep. 2014;6(2):5147doi: 10.4081/idr.2014.5147.
Pérez, P. N., Ramírez, M. A., Fernández, J. A., & de Guevara, L. L. (2014). A Patient Presenting with Cholangitis due to Stenotrophomonas Maltophilia and Pseudomonas Aeruginosa Successfully Treated with Intrabiliary Colistine. Infectious disease reports, 6(2), 5147. https://doi.org/10.4081/idr.2014.5147
Pérez, Pablo N, et al. "A Patient Presenting with Cholangitis due to Stenotrophomonas Maltophilia and Pseudomonas Aeruginosa Successfully Treated with Intrabiliary Colistine." Infectious disease reports vol. 6,2 (2014): 5147. doi: https://doi.org/10.4081/idr.2014.5147
Pérez PN, Ramírez MA, Fernández JA, de Guevara LL. A Patient Presenting with Cholangitis due to Stenotrophomonas Maltophilia and Pseudomonas Aeruginosa Successfully Treated with Intrabiliary Colistine. Infect Dis Rep. 2014 May 13;6(2):5147. doi: 10.4081/idr.2014.5147. eCollection 2014 May 13. PMID: 25002957; PMCID: PMC4083296.
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Current pattern of antibiotic resistance of clinical isolates among conjunctival swabs.

Pakistan journal of medical sciences

Essa Abdullah F, Irfan Khan M, Waheed S.
PMID: 24353513
Pak J Med Sci. 2013 Jan;29(1):81-4. doi: 10.12669/pjms.291.2566.

OBJECTIVES: To identify the etiological agent in bacterial conjunctivitis and to determine the antibiogram of bacterial isolates.METHODOLOGY: This observational study was conducted at Dr. Essa's Laboratory over a period of 12 months ending in March 2012. Two hundred samples...

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Essa Abdullah F, Irfan Khan M, Waheed S. Current pattern of antibiotic resistance of clinical isolates among conjunctival swabs. Pak J Med Sci. 2013;29(1):81-4doi: 10.12669/pjms.291.2566.
Essa Abdullah, F., Irfan Khan, M., & Waheed, S. (2013). Current pattern of antibiotic resistance of clinical isolates among conjunctival swabs. Pakistan journal of medical sciences, 29(1), 81-4. https://doi.org/10.12669/pjms.291.2566
Essa Abdullah, Farhan, et al. "Current pattern of antibiotic resistance of clinical isolates among conjunctival swabs." Pakistan journal of medical sciences vol. 29,1 (2013): 81-4. doi: https://doi.org/10.12669/pjms.291.2566
Essa Abdullah F, Irfan Khan M, Waheed S. Current pattern of antibiotic resistance of clinical isolates among conjunctival swabs. Pak J Med Sci. 2013 Jan;29(1):81-4. doi: 10.12669/pjms.291.2566. PMID: 24353513; PMCID: PMC3809201.
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Antimicrobial susceptibilities of Escherichia coli isolates as agents of community-acquired urinary tract infection (2008-2014).

Turkish journal of urology

Yılmaz N, Ağuş N, Bayram A, Şamlıoğlu P, Şirin MC, Derici YK, Hancı SY.
PMID: 27011879
Turk J Urol. 2016 Mar;42(1):32-6. doi: 10.5152/tud.2016.90836.

OBJECTIVE: Urinary tract infections (UTIs) are among the most frequently seen community-acquired infections worldwide. E. coli causes 90% of urinary system infections. To guide the empirical therapy, the resistance pattern of E. coli responsible for community-acquired UTI was evaluated...

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Yılmaz N, Ağuş N, Bayram A, et al. Antimicrobial susceptibilities of Escherichia coli isolates as agents of community-acquired urinary tract infection (2008-2014). Turk J Urol. 2016;42(1):32-6doi: 10.5152/tud.2016.90836.
Yılmaz, N., Ağuş, N., Bayram, A., Şamlıoğlu, P., Şirin, M. C., Derici, Y. K., & Hancı, S. Y. (2016). Antimicrobial susceptibilities of Escherichia coli isolates as agents of community-acquired urinary tract infection (2008-2014). Turkish journal of urology, 42(1), 32-6. https://doi.org/10.5152/tud.2016.90836
Yılmaz, Nisel, et al. "Antimicrobial susceptibilities of Escherichia coli isolates as agents of community-acquired urinary tract infection (2008-2014)." Turkish journal of urology vol. 42,1 (2016): 32-6. doi: https://doi.org/10.5152/tud.2016.90836
Yılmaz N, Ağuş N, Bayram A, Şamlıoğlu P, Şirin MC, Derici YK, Hancı SY. Antimicrobial susceptibilities of Escherichia coli isolates as agents of community-acquired urinary tract infection (2008-2014). Turk J Urol. 2016 Mar;42(1):32-6. doi: 10.5152/tud.2016.90836. PMID: 27011879; PMCID: PMC4791079.
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Favorable outcome in cerebral abscesses caused by Citrobacter koseri in a newborn infant.

IDCases

Algubaisi S, Bührer C, Thomale UW, Spors B.
PMID: 26793443
IDCases. 2014 Dec 27;2(1):22-4. doi: 10.1016/j.idcr.2014.11.004. eCollection 2015.

The treatment of brain abscesses in newborn infants is controversial. We report on a 6-week-old infant with multiple brain abscesses caused by Citrobacter koseri that resolved after treatment with combined surgical drainage and intravenous therapy with meropenem and fosfomycin.

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Algubaisi S, Bührer C, Thomale UW, et al. Favorable outcome in cerebral abscesses caused by Citrobacter koseri in a newborn infant. IDCases. 2014;2(1):22-4doi: 10.1016/j.idcr.2014.11.004.
Algubaisi, S., Bührer, C., Thomale, U. W., & Spors, B. (2015). Favorable outcome in cerebral abscesses caused by Citrobacter koseri in a newborn infant. IDCases, 2(1), 22-4. https://doi.org/10.1016/j.idcr.2014.11.004
Algubaisi, Sarah, et al. "Favorable outcome in cerebral abscesses caused by Citrobacter koseri in a newborn infant." IDCases vol. 2,1 (2015): 22-4. doi: https://doi.org/10.1016/j.idcr.2014.11.004
Algubaisi S, Bührer C, Thomale UW, Spors B. Favorable outcome in cerebral abscesses caused by Citrobacter koseri in a newborn infant. IDCases. 2014 Dec 27;2(1):22-4. doi: 10.1016/j.idcr.2014.11.004. eCollection 2015. PMID: 26793443; PMCID: PMC4672606.
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Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples.

Frontiers in microbiology

Fu Z, Ma Y, Chen C, Guo Y, Hu F, Liu Y, Xu X, Wang M.
PMID: 26793179
Front Microbiol. 2016 Jan 11;6:1544. doi: 10.3389/fmicb.2015.01544. eCollection 2015.

In China, fosfomycin alone or in combination with other antibiotics is commonly used in the treatment of infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Although fosfomycin-resistant S. aureus strains have continued to emerge and increase, the...

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Fu Z, Ma Y, Chen C, et al. Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples. Front Microbiol. 2016;6:1544doi: 10.3389/fmicb.2015.01544.
Fu, Z., Ma, Y., Chen, C., Guo, Y., Hu, F., Liu, Y., Xu, X., & Wang, M. (2015). Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples. Frontiers in microbiology, 61544. https://doi.org/10.3389/fmicb.2015.01544
Fu, Zhuyingjie, et al. "Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples." Frontiers in microbiology vol. 6 (2015): 1544. doi: https://doi.org/10.3389/fmicb.2015.01544
Fu Z, Ma Y, Chen C, Guo Y, Hu F, Liu Y, Xu X, Wang M. Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples. Front Microbiol. 2016 Jan 11;6:1544. doi: 10.3389/fmicb.2015.01544. eCollection 2015. PMID: 26793179; PMCID: PMC4707275.
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Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic .

Frontiers in microbiology

Kurabayashi K, Tanimoto K, Tomita H, Hirakawa H.
PMID: 28360903
Front Microbiol. 2017 Mar 16;8:426. doi: 10.3389/fmicb.2017.00426. eCollection 2017.

Bacterial infections to anaerobic site are often hard to be treated because the activity of most of antimicrobials decreases under anaerobic conditions. However, fosfomycin rather provides a greater activity under anaerobic conditions than aerobic conditions. Previously, we found that...

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Kurabayashi K, Tanimoto K, Tomita H, et al. Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic . Front Microbiol. 2017;8:426doi: 10.3389/fmicb.2017.00426.
Kurabayashi, K., Tanimoto, K., Tomita, H., & Hirakawa, H. (2017). Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic . Frontiers in microbiology, 8426. https://doi.org/10.3389/fmicb.2017.00426
Kurabayashi, Kumiko, et al. "Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic ." Frontiers in microbiology vol. 8 (2017): 426. doi: https://doi.org/10.3389/fmicb.2017.00426
Kurabayashi K, Tanimoto K, Tomita H, Hirakawa H. Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic . Front Microbiol. 2017 Mar 16;8:426. doi: 10.3389/fmicb.2017.00426. eCollection 2017. PMID: 28360903; PMCID: PMC5352689.
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The use of prophylactic single-dose fosfomycin in patients who undergo transrectal ultrasound-guided prostate biopsy: A prospective, randomized, and controlled clinical study.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Sen V, Aydogdu O, Bozkurt IH, Yonguc T, Sen P, Polat S, Degirmenci T, Bolat D.
PMID: 26788236
Can Urol Assoc J. 2015 Nov-Dec;9(11):E863-7. doi: 10.5489/cuaj.3068. Epub 2015 Dec 14.

INTRODUCTION: We aimed to demonstrate the efficacy, safety, and convenient use of fosfomycin trometamol in the preoperative antibiotic prophylaxis (PAP) of transrectal ultrasound-guided biopsy of the prostate (TRUSBP) in this prospective, randomized study.METHODS: Between May 2014 and May 2015,...

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Sen V, Aydogdu O, Bozkurt IH, et al. The use of prophylactic single-dose fosfomycin in patients who undergo transrectal ultrasound-guided prostate biopsy: A prospective, randomized, and controlled clinical study. Can Urol Assoc J. 2015;9(11):E863-7doi: 10.5489/cuaj.3068.
Sen, V., Aydogdu, O., Bozkurt, I. H., Yonguc, T., Sen, P., Polat, S., Degirmenci, T., & Bolat, D. (2015). The use of prophylactic single-dose fosfomycin in patients who undergo transrectal ultrasound-guided prostate biopsy: A prospective, randomized, and controlled clinical study. Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 9(11), E863-7. https://doi.org/10.5489/cuaj.3068
Sen, Volkan, et al. "The use of prophylactic single-dose fosfomycin in patients who undergo transrectal ultrasound-guided prostate biopsy: A prospective, randomized, and controlled clinical study." Canadian Urological Association journal = Journal de l'Association des urologues du Canada vol. 9,11 (2015): E863-7. doi: https://doi.org/10.5489/cuaj.3068
Sen V, Aydogdu O, Bozkurt IH, Yonguc T, Sen P, Polat S, Degirmenci T, Bolat D. The use of prophylactic single-dose fosfomycin in patients who undergo transrectal ultrasound-guided prostate biopsy: A prospective, randomized, and controlled clinical study. Can Urol Assoc J. 2015 Nov-Dec;9(11):E863-7. doi: 10.5489/cuaj.3068. Epub 2015 Dec 14. PMID: 26788236; PMCID: PMC4707906.
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Showing 1 to 12 of 390 entries