Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 77 entries
Sorted by: Best Match Show Resources per page
NADH Oxidase Activity of Plasma Membranes of Soybean Hypocotyls Is Activated by Guanine Nucleotides.

Plant physiology

Morre DJ, Brightman AO, Barr R, Davidson M, Crane FL.
PMID: 12231849
Plant Physiol. 1993 Jun;102(2):595-602. doi: 10.1104/pp.102.2.595.

The activity of an auxin-stimulated NADH oxidase of the plasma membrane of hypocotyls of etiolated soybean (Glycine max Merr.) seedlings responded to guanine and other nucleotides, but in a manner that differed from that of enzymes coupled to the...

Cite
Morre DJ, Brightman AO, Barr R, et al. NADH Oxidase Activity of Plasma Membranes of Soybean Hypocotyls Is Activated by Guanine Nucleotides. Plant Physiol. 1993;102(2):595-602doi: 10.1104/pp.102.2.595.
Morre, D. J., Brightman, A. O., Barr, R., Davidson, M., & Crane, F. L. (1993). NADH Oxidase Activity of Plasma Membranes of Soybean Hypocotyls Is Activated by Guanine Nucleotides. Plant physiology, 102(2), 595-602. https://doi.org/10.1104/pp.102.2.595
Morre, D. J., et al. "NADH Oxidase Activity of Plasma Membranes of Soybean Hypocotyls Is Activated by Guanine Nucleotides." Plant physiology vol. 102,2 (1993): 595-602. doi: https://doi.org/10.1104/pp.102.2.595
Morre DJ, Brightman AO, Barr R, Davidson M, Crane FL. NADH Oxidase Activity of Plasma Membranes of Soybean Hypocotyls Is Activated by Guanine Nucleotides. Plant Physiol. 1993 Jun;102(2):595-602. doi: 10.1104/pp.102.2.595. PMID: 12231849; PMCID: PMC158817.
Copy Download .nbib Format: NLM
The heterogeneity and nucleotide modulation of cholinergic muscarinic receptors are restored by poly (ethylene) glycol-6000 precipitation of solubilized atrial receptors.

Neurochemistry international

Aguilar JS, Ochoa EL.
PMID: 20493028
Neurochem Int. 1986;8(1):47-51. doi: 10.1016/0197-0186(86)90099-9.

The membrane bound muscarinic receptor exhibits heterogeneity of binding sites for agonists that are modulated by guanine nucleotides. These properties are generally lost upon receptor solubilization by several detergents, but may be recovered after rapid detergent removal by poly...

Cite
Aguilar JS, Ochoa EL. The heterogeneity and nucleotide modulation of cholinergic muscarinic receptors are restored by poly (ethylene) glycol-6000 precipitation of solubilized atrial receptors. Neurochem Int. 1986;8(1):47-51doi: 10.1016/0197-0186(86)90099-9.
Aguilar, J. S., & Ochoa, E. L. (1986). The heterogeneity and nucleotide modulation of cholinergic muscarinic receptors are restored by poly (ethylene) glycol-6000 precipitation of solubilized atrial receptors. Neurochemistry international, 8(1), 47-51. https://doi.org/10.1016/0197-0186(86)90099-9
Aguilar, J S, and Ochoa, E L. "The heterogeneity and nucleotide modulation of cholinergic muscarinic receptors are restored by poly (ethylene) glycol-6000 precipitation of solubilized atrial receptors." Neurochemistry international vol. 8,1 (1986): 47-51. doi: https://doi.org/10.1016/0197-0186(86)90099-9
Aguilar JS, Ochoa EL. The heterogeneity and nucleotide modulation of cholinergic muscarinic receptors are restored by poly (ethylene) glycol-6000 precipitation of solubilized atrial receptors. Neurochem Int. 1986;8(1):47-51. doi: 10.1016/0197-0186(86)90099-9. PMID: 20493028.
Copy Download .nbib Format: NLM
Regulation of putative muscarinic cholinergic receptor subtypes in rat brain.

Neurochemistry international

Norman AB, Battaglia G, Creese I.
PMID: 20493134
Neurochem Int. 1986;9(2):337-47. doi: 10.1016/0197-0186(86)90071-9.

Transection of the fimbria/fornix, producing a 75% reduction in the activity of the cholinergic marker choline-o-acetyltransferase (CAT EC. 2.3.1.6) in rat hippocampus, did not change the binding characteristics of the non-subtype selective, muscarinic cholinergic receptor antagonist ligand [(3)H](?)quinuclidinyl benzilate...

Cite
Norman AB, Battaglia G, Creese I. Regulation of putative muscarinic cholinergic receptor subtypes in rat brain. Neurochem Int. 1986;9(2):337-47doi: 10.1016/0197-0186(86)90071-9.
Norman, A. B., Battaglia, G., & Creese, I. (1986). Regulation of putative muscarinic cholinergic receptor subtypes in rat brain. Neurochemistry international, 9(2), 337-47. https://doi.org/10.1016/0197-0186(86)90071-9
Norman, A B, et al. "Regulation of putative muscarinic cholinergic receptor subtypes in rat brain." Neurochemistry international vol. 9,2 (1986): 337-47. doi: https://doi.org/10.1016/0197-0186(86)90071-9
Norman AB, Battaglia G, Creese I. Regulation of putative muscarinic cholinergic receptor subtypes in rat brain. Neurochem Int. 1986;9(2):337-47. doi: 10.1016/0197-0186(86)90071-9. PMID: 20493134.
Copy Download .nbib Format: NLM
Characterization and regional distribution of adenylyl cyclase activity from human brain.

Neurochemistry international

Cowburn RF, Garlind A, O'Neill C, Alafuzoff I, Winblad B, Fowler CJ.
PMID: 20504716
Neurochem Int. 1991;18(3):389-98. doi: 10.1016/0197-0186(91)90171-9.

The characteristics of the human brain adenylyl cyclase complex were studied in membranes from post-mortem frontal cortex. Basal, guanine nucleotide, sodium fluoride and forskolin stimulated activities were highly magnesium-dependent. Sodium fluoride and guanine nucleotides gave bi-phasic responses, with both...

Cite
Cowburn RF, Garlind A, O'Neill C, et al. Characterization and regional distribution of adenylyl cyclase activity from human brain. Neurochem Int. 1991;18(3):389-98doi: 10.1016/0197-0186(91)90171-9.
Cowburn, R. F., Garlind, A., O'Neill, C., Alafuzoff, I., Winblad, B., & Fowler, C. J. (1991). Characterization and regional distribution of adenylyl cyclase activity from human brain. Neurochemistry international, 18(3), 389-98. https://doi.org/10.1016/0197-0186(91)90171-9
Cowburn, R F, et al. "Characterization and regional distribution of adenylyl cyclase activity from human brain." Neurochemistry international vol. 18,3 (1991): 389-98. doi: https://doi.org/10.1016/0197-0186(91)90171-9
Cowburn RF, Garlind A, O'Neill C, Alafuzoff I, Winblad B, Fowler CJ. Characterization and regional distribution of adenylyl cyclase activity from human brain. Neurochem Int. 1991;18(3):389-98. doi: 10.1016/0197-0186(91)90171-9. PMID: 20504716.
Copy Download .nbib Format: NLM
Activation and Desensitization of Rat A.

Drug development research

Park KS, Hoffmann C, Kim HO, Padgett WL, Daly JW, Brambilla R, Motta C, Abbracchio MP, Jacobson KA.
PMID: 23487508
Drug Dev Res. 1998 Jun 01;44(2):97-105. doi: 10.1002/(SICI)1098-2299(199806/07)44:2/3<97::AID-DDR7>3.0.CO;2-5.

Strategy, Management and Health PolicyVenture Capital Enabling TechnologyPreclinical ResearchPreclinical Development Toxicology, Formulation Drug Delivery, PharmacokineticsClinical Development Phases I-III Regulatory, Quality, ManufacturingPostmarketing Phase IV Xanthine and adenosine derivatives, known to bind to recombinant rat A

Cite
Park KS, Hoffmann C, Kim HO, et al. Activation and Desensitization of Rat A. Drug Dev Res. 1998;44(2):97-105doi: 10.1002/(SICI)1098-2299(199806/07)44:2/3<97::AID-DDR7>3.0.CO;2-5.
Park, K. S., Hoffmann, C., Kim, H. O., Padgett, W. L., Daly, J. W., Brambilla, R., Motta, C., Abbracchio, M. P., & Jacobson, K. A. (1998). Activation and Desensitization of Rat A. Drug development research, 44(2), 97-105. https://doi.org/10.1002/(SICI)1098-2299(199806/07)44:2/3<97::AID-DDR7>3.0.CO;2-5
Park, Kyung-Sun, et al. "Activation and Desensitization of Rat A." Drug development research vol. 44,2 (1998): 97-105. doi: https://doi.org/10.1002/(SICI)1098-2299(199806/07)44:2/3<97::AID-DDR7>3.0.CO;2-5
Park KS, Hoffmann C, Kim HO, Padgett WL, Daly JW, Brambilla R, Motta C, Abbracchio MP, Jacobson KA. Activation and Desensitization of Rat A. Drug Dev Res. 1998 Jun 01;44(2):97-105. doi: 10.1002/(SICI)1098-2299(199806/07)44:2/3<97::AID-DDR7>3.0.CO;2-5. PMID: 23487508; PMCID: PMC3589805.
Copy Download .nbib Format: NLM
Early-stage structure-based drug discovery for small GTPases by NMR spectroscopy.

Pharmacology & therapeutics

Yin G, Lv G, Zhang J, Jiang H, Lai T, Yang Y, Ren Y, Wang J, Yi C, Chen H, Huang Y, Xiao C.
PMID: 35007659
Pharmacol Ther. 2022 Jan 07;108110. doi: 10.1016/j.pharmthera.2022.108110. Epub 2022 Jan 07.

Small GTPase or Ras superfamily, including Ras, Rho, Rab, Ran and Arf, are fundamental in regulating a wide range of cellular processes such as growth, differentiation, migration and apoptosis. They share structural and functional similarities for binding guanine nucleotides...

Cite
Yin G, Lv G, Zhang J, et al. Early-stage structure-based drug discovery for small GTPases by NMR spectroscopy. Pharmacol Ther. 2022;108110doi: 10.1016/j.pharmthera.2022.108110.
Yin, G., Lv, G., Zhang, J., Jiang, H., Lai, T., Yang, Y., Ren, Y., Wang, J., Yi, C., Chen, H., Huang, Y., & Xiao, C. (2022). Early-stage structure-based drug discovery for small GTPases by NMR spectroscopy. Pharmacology & therapeutics, 108110. https://doi.org/10.1016/j.pharmthera.2022.108110
Yin, Guowei, et al. "Early-stage structure-based drug discovery for small GTPases by NMR spectroscopy." Pharmacology & therapeutics vol. (2022): 108110. doi: https://doi.org/10.1016/j.pharmthera.2022.108110
Yin G, Lv G, Zhang J, Jiang H, Lai T, Yang Y, Ren Y, Wang J, Yi C, Chen H, Huang Y, Xiao C. Early-stage structure-based drug discovery for small GTPases by NMR spectroscopy. Pharmacol Ther. 2022 Jan 07;108110. doi: 10.1016/j.pharmthera.2022.108110. Epub 2022 Jan 07. PMID: 35007659.
Copy Download .nbib Format: NLM
Discovery of Novel GMPS Inhibitors of .

Biology

Nan J, Zhang S, Zhan P, Jiang L.
PMID: 34203217
Biology (Basel). 2021 Jun 28;10(7). doi: 10.3390/biology10070594.

Citrus production is facing an unprecedented problem because of huanglongbing (HLB) disease. Presently, no effective HLB-easing method is available when citrus becomes infected. Guanosine 5'-monophosphate synthetase (GMPS) is a key protein in the de novo synthesis of guanine nucleotides....

Cite
Nan J, Zhang S, Zhan P, et al. Discovery of Novel GMPS Inhibitors of . Biology (Basel). 2021;10(7)doi: 10.3390/biology10070594.
Nan, J., Zhang, S., Zhan, P., & Jiang, L. (2021). Discovery of Novel GMPS Inhibitors of . Biology, 10(7), . https://doi.org/10.3390/biology10070594
Nan, Jing, et al. "Discovery of Novel GMPS Inhibitors of ." Biology vol. 10,7 (2021). doi: https://doi.org/10.3390/biology10070594
Nan J, Zhang S, Zhan P, Jiang L. Discovery of Novel GMPS Inhibitors of . Biology (Basel). 2021 Jun 28;10(7). doi: 10.3390/biology10070594. PMID: 34203217; PMCID: PMC8301025.
Copy Download .nbib Format: NLM
Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies.

Journal of pharmaceutical and biomedical analysis

Şenel P, Agar S, İş YS, Altay F, Gölcü A, Yurtsever M.
PMID: 34875572
J Pharm Biomed Anal. 2022 Feb 05;209:114490. doi: 10.1016/j.jpba.2021.114490. Epub 2021 Nov 24.

Pemetrexed is a well-known and widely used antineoplastic drug under the category of cytotoxic, folate anti-metabolites that is used in chemotherapeutic treatments, especially in malignant mesothelioma and non-small cell lung carcinoma. Here, the binding mechanism and interactions of Pemetrexed...

Cite
Şenel P, Agar S, İş YS, et al. Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies. J Pharm Biomed Anal. 2021;209:114490doi: 10.1016/j.jpba.2021.114490.
Şenel, P., Agar, S., İş, Y. S., Altay, F., Gölcü, A., & Yurtsever, M. (2022). Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies. Journal of pharmaceutical and biomedical analysis, 209114490. https://doi.org/10.1016/j.jpba.2021.114490
Şenel, Pelin, et al. "Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies." Journal of pharmaceutical and biomedical analysis vol. 209 (2022): 114490. doi: https://doi.org/10.1016/j.jpba.2021.114490
Şenel P, Agar S, İş YS, Altay F, Gölcü A, Yurtsever M. Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies. J Pharm Biomed Anal. 2022 Feb 05;209:114490. doi: 10.1016/j.jpba.2021.114490. Epub 2021 Nov 24. PMID: 34875572.
Copy Download .nbib Format: NLM
QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum.

Journal of molecular graphics & modelling

Asmare MM, Nitin N, Yun SI, Mahapatra RK.
PMID: 34911011
J Mol Graph Model. 2021 Dec 10;111:108108. doi: 10.1016/j.jmgm.2021.108108. Epub 2021 Dec 10.

Cryptosporidium parvum (Cp) causes a gastro-intestinal disease called Cryptosporidiosis. C. parvum Inosine 5' monophosphate dehydrogenase (CpIMPDH) is responsible for the production of guanine nucleotides. In the present study, 37 known urea-based congeneric compounds were used to build a 2D...

Cite
Asmare MM, Nitin N, Yun SI, et al. QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum. J Mol Graph Model. 2021;111:108108doi: 10.1016/j.jmgm.2021.108108.
Asmare, M. M., Nitin, N., Yun, S. I., & Mahapatra, R. K. (2021). QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum. Journal of molecular graphics & modelling, 111108108. https://doi.org/10.1016/j.jmgm.2021.108108
Asmare, Misgana Mengistu, et al. "QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum." Journal of molecular graphics & modelling vol. 111 (2021): 108108. doi: https://doi.org/10.1016/j.jmgm.2021.108108
Asmare MM, Nitin N, Yun SI, Mahapatra RK. QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum. J Mol Graph Model. 2021 Dec 10;111:108108. doi: 10.1016/j.jmgm.2021.108108. Epub 2021 Dec 10. PMID: 34911011.
Copy Download .nbib Format: NLM
Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies.

Journal of pharmaceutical and biomedical analysis

Şenel P, Agar S, İş YS, Altay F, Gölcü A, Yurtsever M.
PMID: 34875572
J Pharm Biomed Anal. 2021 Nov 24;209:114490. doi: 10.1016/j.jpba.2021.114490. Epub 2021 Nov 24.

Pemetrexed is a well-known and widely used antineoplastic drug under the category of cytotoxic, folate anti-metabolites that is used in chemotherapeutic treatments, especially in malignant mesothelioma and non-small cell lung carcinoma. Here, the binding mechanism and interactions of Pemetrexed...

Cite
Şenel P, Agar S, İş YS, et al. Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies. J Pharm Biomed Anal. 2021;209:114490doi: 10.1016/j.jpba.2021.114490.
Şenel, P., Agar, S., İş, Y. S., Altay, F., Gölcü, A., & Yurtsever, M. (2021). Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies. Journal of pharmaceutical and biomedical analysis, 209114490. https://doi.org/10.1016/j.jpba.2021.114490
Şenel, Pelin, et al. "Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies." Journal of pharmaceutical and biomedical analysis vol. 209 (2021): 114490. doi: https://doi.org/10.1016/j.jpba.2021.114490
Şenel P, Agar S, İş YS, Altay F, Gölcü A, Yurtsever M. Deciphering the mechanism and binding interactions of Pemetrexed with dsDNA with DNA-targeted chemotherapeutics via spectroscopic, analytical, and simulation studies. J Pharm Biomed Anal. 2021 Nov 24;209:114490. doi: 10.1016/j.jpba.2021.114490. Epub 2021 Nov 24. PMID: 34875572.
Copy Download .nbib Format: NLM
COVID-19 prediction based on genome similarity of human SARS-CoV-2 and bat SARS-CoV-like coronavirus.

Computers & industrial engineering

Arslan H.
PMID: 34511707
Comput Ind Eng. 2021 Nov;161:107666. doi: 10.1016/j.cie.2021.107666. Epub 2021 Sep 08.

This paper proposes an efficient and accurate method to predict coronavirus disease 19 (COVID-19) based on the genome similarity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a bat SARS-CoV-like coronavirus. We introduce similarity features to distinguish...

Cite
Arslan H. COVID-19 prediction based on genome similarity of human SARS-CoV-2 and bat SARS-CoV-like coronavirus. Comput Ind Eng. 2021;161:107666doi: 10.1016/j.cie.2021.107666.
Arslan, H. (2021). COVID-19 prediction based on genome similarity of human SARS-CoV-2 and bat SARS-CoV-like coronavirus. Computers & industrial engineering, 161107666. https://doi.org/10.1016/j.cie.2021.107666
Arslan, Hilal. "COVID-19 prediction based on genome similarity of human SARS-CoV-2 and bat SARS-CoV-like coronavirus." Computers & industrial engineering vol. 161 (2021): 107666. doi: https://doi.org/10.1016/j.cie.2021.107666
Arslan H. COVID-19 prediction based on genome similarity of human SARS-CoV-2 and bat SARS-CoV-like coronavirus. Comput Ind Eng. 2021 Nov;161:107666. doi: 10.1016/j.cie.2021.107666. Epub 2021 Sep 08. PMID: 34511707; PMCID: PMC8423779.
Copy Download .nbib Format: NLM
QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum.

Journal of molecular graphics & modelling

Asmare MM, Nitin N, Yun SI, Mahapatra RK.
PMID: 34911011
J Mol Graph Model. 2021 Dec 10;111:108108. doi: 10.1016/j.jmgm.2021.108108. Epub 2021 Dec 10.

Cryptosporidium parvum (Cp) causes a gastro-intestinal disease called Cryptosporidiosis. C. parvum Inosine 5' monophosphate dehydrogenase (CpIMPDH) is responsible for the production of guanine nucleotides. In the present study, 37 known urea-based congeneric compounds were used to build a 2D...

Cite
Asmare MM, Nitin N, Yun SI, et al. QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum. J Mol Graph Model. 2021;111:108108doi: 10.1016/j.jmgm.2021.108108.
Asmare, M. M., Nitin, N., Yun, S. I., & Mahapatra, R. K. (2021). QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum. Journal of molecular graphics & modelling, 111108108. https://doi.org/10.1016/j.jmgm.2021.108108
Asmare, Misgana Mengistu, et al. "QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum." Journal of molecular graphics & modelling vol. 111 (2021): 108108. doi: https://doi.org/10.1016/j.jmgm.2021.108108
Asmare MM, Nitin N, Yun SI, Mahapatra RK. QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum. J Mol Graph Model. 2021 Dec 10;111:108108. doi: 10.1016/j.jmgm.2021.108108. Epub 2021 Dec 10. PMID: 34911011.
Copy Download .nbib Format: NLM
Showing 1 to 12 of 77 entries