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Showing 1 to 12 of 128 entries
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HLA antigens in individuals with down syndrome and alopecia areata.

World journal of clinical cases

Estefan JL, Oliveira JC, Abad ED, Saintive SB, Porto LC, Ribeiro M.
PMID: 25325065
World J Clin Cases. 2014 Oct 16;2(10):541-5. doi: 10.12998/wjcc.v2.i10.541.

AIM: To describe human leukocyte antigen (HLA) alleles in individuals with Down syndrome and alopecia areata.METHODS: A cross-sectional study was conducted, which evaluated 109 individuals. Ten with down syndrome (DS) and alopecia areata (AA), ten with DS without AA...

T-cell-mediated drug hypersensitivity: immune mechanisms and their clinical relevance.

Asia Pacific allergy

Yun J, Cai F, Lee FJ, Pichler WJ.
PMID: 27141480
Asia Pac Allergy. 2016 Apr;6(2):77-89. doi: 10.5415/apallergy.2016.6.2.77. Epub 2016 Apr 28.

T-cell-mediated drug hypersensitivity represents a significant proportion of immune mediated drug hypersensitivity reactions. In the recent years, there has been an increase in understanding the immune mechanisms behind T-cell-mediated drug hypersensitivity. According to hapten mechanism, drug specific T-cell response...

The Association between Human Leukocyte Antigens and Hypertensive End-Stage Renal Failure among Yemeni Patients.

Sultan Qaboos University medical journal

Nassar MY, Al-Shamahy HA, Masood HA.
PMID: 26052458
Sultan Qaboos Univ Med J. 2015 May;15(2):e241-9. Epub 2015 May 28.

OBJECTIVES: Many studies have attempted to locate a connection between various genetic factors and the pathogenesis of certain diseases. A number of these have found human leukocyte antigens (HLAs) to be the most significant genetic factors affecting the susceptibility...

Complementarity of Binding Motifs is a General Property of HLA-A and HLA-B Molecules and Does Not Seem to Effect HLA Haplotype Composition.

Frontiers in immunology

Rao X, De Boer RJ, van Baarle D, Maiers M, Kesmir C.
PMID: 24294213
Front Immunol. 2013 Nov 14;4:374. doi: 10.3389/fimmu.2013.00374. eCollection 2013.

Different human leukocyte antigen (HLA) haplotypes (i.e., the specific combinations of HLA-A, -B, -DR alleles inherited together from one parent) are observed in different frequencies in human populations. Some haplotypes, like HLA-A1-B8, are very frequent, reaching up to 10%...

HLA-C*17, DQB1*03:01, DQA1*01:03 and DQA1*05:05 Alleles Associated to Bullous Pemphigoid in Brazilian Population.

Annals of dermatology

Chagury AA, Sennes LU, Gil JM, Kalil J, Rodrigues H, Rosales CB, Miziara ID.
PMID: 29386826
Ann Dermatol. 2018 Feb;30(1):8-12. doi: 10.5021/ad.2018.30.1.8. Epub 2017 Dec 26.

BACKGROUND: Bullous pemphigoid (BP) is an autoimmune disease with bullous vesicles and an incidence of 0.2 to 1.4 per 100,000 inhabitants. Many studies have been published demonstrating the association of pemphigoid with HLA class II system alleles in different...

Enrichment of HLA Types and Single-Nucleotide Polymorphism Associated With Non-progression in a Strictly Defined Cohort of HIV-1 Controllers.

Frontiers in immunology

Westrop SJ, Cocker ATH, Boasso A, Sullivan AK, Nelson MR, Imami N.
PMID: 28702030
Front Immunol. 2017 Jun 27;8:746. doi: 10.3389/fimmu.2017.00746. eCollection 2017.

HIV-1 controllers (HIC) are extremely rare patients with the ability to control viral replication, maintain unchanging CD4 T-cell count, and evade disease progression for extensive periods of time, in the absence of antiretroviral therapy. In order to establish the...

The relevance of a bank with genotyped platelets donors.

Hematology, transfusion and cell therapy

Barbagallo NBA, Costa TH, Bastos E, Aravechia MG, Kutner JM, Bonet-Bub C.
PMID: 34083156
Hematol Transfus Cell Ther. 2021 May 18; doi: 10.1016/j.htct.2021.03.006. Epub 2021 May 18.

OBJECTIVE: Describe the clinical and laboratory characteristics and the transfusion strategy of patients at Hospital Israelita Albert Einstein with platelet refractoriness and identify their etiological characteristics. Standardize the platelet immunofluorescence technique by flow cytometry as a test for platelet...

T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation.

Frontiers in immunology

Peereboom ETM, Matern BM, Tomosugi T, Niemann M, Drylewicz J, Joosten I, Allebes WA, van der Meer A, Hilbrands LB, Baas MC, van Reekum FE, Verhaar MC, Kamburova EG, Seelen MAJ, Sanders JS, Hepkema BG, Lambeck AJ, Bungener LB, Roozendaal C, Tilanus MGJ, Voorter CE, Wieten L, van Duijnhoven EM, Gelens MACJ, Christiaans MHL, van Ittersum FJ, Nurmohamed A, Lardy NM, Swelsen W, van der Pant KA, van der Weerd NC, Ten Berge IJM, Bemelman FJ, de Vries APJ, de Fijter JW, Betjes MGH, Roelen DL, Claas FH, Otten HG, Heidt S, van Zuilen AD, Kobayashi T, Geneugelijk K, Spierings E.
PMID: 34868064
Front Immunol. 2021 Nov 18;12:784040. doi: 10.3389/fimmu.2021.784040. eCollection 2021.


Kidney transplantation in highly sensitized recipients.

Kidney research and clinical practice

Park Y, Ko EJ, Chung BH, Yang CW.
PMID: 34233438
Kidney Res Clin Pract. 2021 Sep;40(3):355-370. doi: 10.23876/j.krcp.21.012. Epub 2021 Jun 25.

In kidney transplantation (KT), overcoming donor shortage is particularly challenging in patients with preexisting donor-specific antibodies (DSAs) against human leukocyte antigen (HLA), called HLA-incompatible KT (HLAi KT), carrying the risk of rejection and allograft loss. Thus, it is necessary...

Editorial: HLA-G-Mediated Immune Tolerance: Past and New Outlooks.

Frontiers in immunology

Gregori S.
PMID: 28082987
Front Immunol. 2016 Dec 27;7:653. doi: 10.3389/fimmu.2016.00653. eCollection 2016.

No abstract available.

Stevens-Johnson syndrome / toxic epidermal necrolysis: an Asia-Pacific perspective.

Asia Pacific allergy

Thong BY.
PMID: 24260726
Asia Pac Allergy. 2013 Oct;3(4):215-23. doi: 10.5415/apallergy.2013.3.4.215. Epub 2013 Oct 31.

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions (SCAR) to drugs which are associated with significant morbidity and mortality. High risk drugs in Asia are similar to those reported worldwide. Human leukocyte antigen (HLA)-related...

Human leukocyte antigens and epstein-barr virus-associated nasopharyngeal carcinoma: old associations offer new clues into the role of immunity in infection-associated cancers.

Frontiers in oncology

Su WH, Hildesheim A, Chang YS.
PMID: 24367763
Front Oncol. 2013 Dec 09;3:299. doi: 10.3389/fonc.2013.00299.

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated tumor. In addition to EBV, host genetic factors are believed to be important determinants of NPC risk. Of all genes studies to date, human leukocyte antigen (HLA) genes have shown...

Showing 1 to 12 of 128 entries