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Showing 1 to 12 of 73 entries
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Properties and ionic self-assembled structures from mixture of a bola-type strong alkali dication and a branched phosphoric acid.

Journal of colloid and interface science

Li Y, Li H, Chai J, Chen M, Yang Q, Hao J.
PMID: 27031597
J Colloid Interface Sci. 2016 Jun 15;472:157-66. doi: 10.1016/j.jcis.2016.03.047. Epub 2016 Mar 21.

Ionic self-assembled structures have been prepared successfully between di-(2-ethylhexyl) phosphoric acid (DEHPA) and hexamethonium hydroxide (HMO(OH)2). The DEHPA/HMO(OH)2 complexes show good surface activity at a wide mixing molar ratio of DEHPA to HMO(OH)2 (ρ), within which the critical micellar...

Voltage-Sensitive K(+) Channels Inhibit Parasympathetic Ganglion Transmission and Vagal Control of Heart Rate in Hypertensive Rats.

Frontiers in neurology

Berg T.
PMID: 26696959
Front Neurol. 2015 Dec 08;6:260. doi: 10.3389/fneur.2015.00260. eCollection 2015.

Parasympathetic withdrawal plays an important role in the autonomic dysfunctions in hypertension. Since hyperpolarizing, voltage-sensitive K(+) channels (K V) hamper transmitter release, elevated K V-activity may explain the disturbed vagal control of heart rate (HR) in hypertension. Here, the...

Role of Nicotinic Acetylcholine Receptor α3 and α7 Subunits in Detrusor Overactivity Induced by Partial Bladder Outlet Obstruction in Rats.

International neurourology journal

Kim HS, Park WJ, Park EY, Koh JS, Hwang TK, Kim JC.
PMID: 25833476
Int Neurourol J. 2015 Mar;19(1):12-8. doi: 10.5213/inj.2015.19.1.12. Epub 2015 Mar 26.

PURPOSE: To investigate the role of α3 and α7 nicotinic acetylcholine receptor subunits (nAChRs) in the bladder, using a rat model with detrusor overactivity induced by partial bladder outlet obstruction (BOO).METHODS: Forty Sprague-Dawley rats were used: 10 were sham-operated...

Nicotine Effects and Receptor Expression on Human Spermatozoa: Possible Neuroendocrine Mechanism.

Frontiers in physiology

Condorelli RA, La Vignera S, Giacone F, Iacoviello L, Mongioì LM, Li Volti G, Barbagallo I, Avola R, Calogero AE.
PMID: 28400736
Front Physiol. 2017 Mar 28;8:177. doi: 10.3389/fphys.2017.00177. eCollection 2017.

The aim of this experimental study was to investigate the mechanism by which nicotine (NIC) alters spermatozoa and to evaluate the expression of nicotinic receptors (nAChR) subunits in human spermatozoa. We analyzed 30 healthy normozoospermic men. Spermatozoa were incubated...

Alkaloids in Erythrina by UPLC-ESI-MS and In Vivo Hypotensive Potential of Extractive Preparations.

Evidence-based complementary and alternative medicine : eCAM

Merlugo L, Santos MC, Sant'Anna LS, Cordeiro EW, Batista LA, Miotto ST, Garcia CV, Moreira CM, Mendez AS.
PMID: 26356581
Evid Based Complement Alternat Med. 2015;2015:959081. doi: 10.1155/2015/959081. Epub 2015 Aug 18.

Erythrina species are used in popular medicine as sedative, anxiolytic, anti-inflammatory, and antihypertensive. In this work, we investigated the chemical composition of extracts obtained from leaves of E. falcata and E. crista-galli. The hypotensive potential of E. falcata and...

An examination of certain factors which might, or do, affect the vascular response to oxytocin.

The Journal of physiology

Lloyd S, Pickford M.
PMID: 16992296
J Physiol. 1967 Dec;193(3):547-69. doi: 10.1113/jphysiol.1967.sp008378.

1. A number of different observations were made on anaesthetized rats and some dogs to try to discover why it is that oxytocin is a vasodilator in dioestrus and anoestrus, and develops constrictor properties in oestrus and following sympathectomy.2....

Peripheral actions of hexamethonium in relation to the decreasing effects of repeated doses on the blood pressure of anaesthetized rats.

British journal of pharmacology and chemotherapy

Blackman JG, Laverty R.
PMID: 19108154
Br J Pharmacol Chemother. 1961 Aug;17(1):124-30. doi: 10.1111/j.1476-5381.1961.tb01112.x.

When hexamethonium was given intravenously to anaesthetized rats, the depressor response produced by successive doses became less. This effect was not related to the duration of anaesthesia and the possible recovery of cardiovascular reflex activity. When the rat's own...

Studies on putative neurotransmitters in the distal retina.

Neurochemistry international

Drujan BD, Negishi K, Laufer M.
PMID: 20487732
Neurochem Int. 1980;1:143-50. doi: 10.1016/0197-0186(80)90057-1.

Histochemical and cytochemical studies of the retinas of the teleosts Carassius carassius and Eugerres plumieri revealed that acetylcholinesterase, besides its main localization in the inner retinal layers, can be also found in the outer plexiform and inner nuclear layers,...

Imaging stretch-activated firing of spinal afferent nerve endings in mouse colon.

Frontiers in neuroscience

Travis L, Spencer NJ.
PMID: 24109427
Front Neurosci. 2013 Oct 07;7:179. doi: 10.3389/fnins.2013.00179. eCollection 2013.

Spinal afferent neurons play a major role in detecting noxious and innocuous stimuli from visceral organs, such as the gastrointestinal tract. However, all our understanding about spinal afferents has been obtained from recordings of spinal afferent axons, or cell...

A new family of two-dimensional zeolites prepared from the intermediate layered precursor IPC-3P obtained during the synthesis of TUN zeolite.

Chemistry (Weinheim an der Bergstrasse, Germany)

Kubů M, Roth WJ, Greer HF, Zhou W, Morris RE, Přech J, Čejka J.
PMID: 24038214
Chemistry. 2013 Oct 04;19(41):13937-45. doi: 10.1002/chem.201300096. Epub 2013 Aug 23.

The crystallization of zeolite TUN with 1,4-bis(N-methylpyrrolidinium)butane as template proceeds through an intermediate, designated IPC-3P, following the Ostwald rule of successive transformations. This apparently layered transient product has been thoroughly investigated and found to consist of MWW monolayers stacked...

Effect of nicotine and alpha-7 nicotinic modulators on visceral pain-induced conditioned place aversion in mice.

European journal of pain (London, England)

Bagdas D, Meade JA, Alkhlaif Y, Muldoon PP, Carroll FI, Damaj MI.
PMID: 29633429
Eur J Pain. 2018 Apr 10; doi: 10.1002/ejp.1231. Epub 2018 Apr 10.

BACKGROUND: Preclinical assays of affective and sensorial aspects of nociception play a key role in research on both the neurobiology of pain and the development of novel analgesics. Therefore, we investigated the effects of nicotine and alpha-7 nicotinic acetylcholine...

Analysis of responses to angiotensin II in the mouse.

Journal of the renin-angiotensin-aldosterone system : JRAAS

Bivalacqua TJ, Champion HC, Hyman AL, McNamara DB, Kadowitz PJ.
PMID: 28095236
J Renin Angiotensin Aldosterone Syst. 2001 Mar;2(1):S48-S53. doi: 10.1177/14703203010020010801.

Responses to angiotensin II (Ang II) were investigated in anaesthetised CD1 mice. Injections of Ang II caused dose-related increases in systemic arterial pressure that were antagonised by candesartan. Responses to Ang II were not altered by PD 123319. At...

Showing 1 to 12 of 73 entries