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Showing 1 to 12 of 44 entries
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Molecular Genetic Testing in Pain and Addiction: Facts, Fiction and Clinical Utility.

Addiction genetics

Blum K, Hauser M, Fratantonio J, Badgaiyan RD.
PMID: 26807291
Addict Genet. 2015 Jul 01;2(1):1-5. doi: 10.1515/addge-2015-0001. Epub 2015 Aug 28.

The Brain Reward Cascade (BRC) is an interaction of neurotransmitters and their respective genes to control the amount of dopamine released within the brain. Any variations within this pathway, whether genetic or environmental (epigenetic), may result in addictive behaviors...

Nonconscious processing and a novel target for schizophrenia research.

Open journal of psychiatry

Badgaiyan RD.
PMID: 24404419
Open J Psychiatr. 2012 Nov 01;2(4). doi: 10.4236/ojpsych.2012.224047.

Analysis of the pattern of altered cognition observed in schizophrenia provides better insight into neurocognitive deficits. It reveals a potential novel target for schizophrenia research. To understand this target we reviewed the findings of neuroimaging studies on implicit [nonconscious]...

GLOBAL OPIOID EPIDEMIC: DOOMED TO FAIL WITHOUT GENETICALLY BASED PRECISION ADDICTION MEDICINE (PAM.

Precision medicine

Blum K, Modestino EJ, Gondré-Lewis MC, Neary J, Siwicki D, Hauser M, Barh D, Steinberg B, Badgaiyan RD.
PMID: 29372187
Precis Med (Bangalore). 2017;2(1):17-22. Epub 2017 Nov 18.

It is a reality that globally opioid deaths have soared for men and women of all social, economic status and age from heroin and fentanyl overdoses. Specifically, in the United States, deaths from narcotic overdoses have reached alarming metrics...

Our evolved unique pleasure circuit makes humans different from apes: Reconsideration of data derived from animal studies.

Journal of systems and integrative neuroscience

Blum K, Gondré-Lewis M, Steinberg B, Elman I, Baron D, Modestino EJ, Badgaiyan RD, Gold MS.
PMID: 30956812
J Syst Integr Neurosci. 2018 Jun;4(1). doi: 10.15761/JSIN.1000191. Epub 2018 Feb 28.

The brain regions tied to pleasure can be triggered by engaging in sex, eating tasty food, watching a movie, accomplishments at school and athletics, consuming drugs, and noble efforts to help the community, the country, and the world. It...

The Benefits of Genetic Addiction Risk Score (GARS.

International journal of genomics and data mining

Blum K, Modestino EJ, Gondre-Lewis M, Chapman EJ, Neary J, Siwicki D, Baron D, Hauser M, Smith DE, Roy AK, Thanos PK, Steinberg B, McLaughlin T, Fried L, Barh D, Dunston GA, Badgaiyan RD.
PMID: 30198022
Int J Genom Data Min. 2018;2018(1). doi: 10.29014/IJGD-115.000015. Epub 2018 Jan 15.

Following 25 years of extensive research by many scientists worldwide, a panel of ten reward gene risk variants, called the Genetic Addiction Risk Score (GARS), has been developed. In unpublished work, when GARS was compared to the Addiction Severity...

The benefits of genetic addiction risk score (GARS™) and pro-dopamine regulation in combating suicide in the American Indian population.

Journal of systems and integrative neuroscience

Blum K, Siwicki D, Baron D, Modestino EJ, Badgaiyan RD.
PMID: 31660252
J Syst Integr Neurosci. 2018 Sep 14;4. doi: 10.15761/JSIN.1000195.

It is well-known that Native Americans (NA) clinically present with a very high rate of alcoholism and other drugs of abuse. It is also known that NA also display a very high rate of suicide compared to other ethnic...

Pro-Dopamine Regulator (KB220) A Fifty Year Sojourn to Combat Reward Deficiency Syndrome (RDS): Evidence Based Bibliography (Annotated).

CPQ neurology and psychology

Kenneth B, Edward MJ, Marjorie GLC, David B, Bruce S, Panayotis TK, William DB, Davis S, Lisa L, Eric BR, Mark M, David M, Lyle F, Rajendra BD.
PMID: 30957097
CPQ Neurol Psychol. 2018;1(2). Epub 2018 Dec 04.

BACKGROUND: We are facing a significant challenge in combatting the current opioid and drug epidemic worldwide. In the USA, although there has been notable progress, in 2017 alone 72,000 people died from a narcotic overdose. The NIAAA & NIDA...

Endorphinergic Enhancement Attenuation of Post-traumatic Stress Disorder (PTSD) .

Current psychopharmacology

Blum K, Modestino EJ, Baron D, Brewer R, Thanos P, Elman I, Badgaiyan RD, Downs BW, Bagchi D, McLaughlin T, Bowirrat A, Roy AK, Gold MS.
PMID: 34466374
Curr Psychopharmacol. 2021 Aug 01;10(2):86-97. doi: 10.2174/2211556009999210104221215.

INTRODUCTION: Polymorphic gene variants, particularly the genetic determinants of low dopamine function (hypodopaminergia), are known to associate with Substance Use Disorder (SUD) and a predisposition to PTSD. Addiction research and molecular genetic applied technologies supported by the National Institutes...

Genetic Addiction Risk Score (GARS.

Current trends in medical diagnostic methods

Blum K, Lott L, Siwicki D, Fried L, Hauser M, Simpatico T, Baron D, Howeedy A, Badgaiyan RD.
PMID: 31276118
Curr Trends Med Diagn Methods. 2018;1(1). doi: 10.29011/CTMDM-101.100001. Epub 2018 Sep 11.

No abstract available.

Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?.

EC psychology and psychiatry

Blum K, Baron D, Badgaiyan RD, Gold MS.
PMID: 31276119
EC Psychol Psychiatr. 2019 Apr 15;8(5):318-321.

No abstract available.

Addiction Research and Therapy in the 21.

Journal of addiction research & therapy

Blum K, Badgaiyan RD.
PMID: 25419476
J Addict Res Ther. 2013;4. doi: 10.4172/2155-6105.1000e117.

No abstract available.

Insurance Companies Fighting the Peer Review Empire without any Validity: the Case for Addiction and Pain Modalities in the face of an American Drug Epidemic.

SEJ surgery and pain

Blum K, Jacobs W, Modestino EJ, DiNubile N, Baron D, McLaughlin T, Siwicki D, Elman I, Moran M, Braverman ER, Thanos PK, Badgaiyan RD.
PMID: 29911684
SEJ Surg Pain. 2018 Oct 04;1(1):1-11.

The United States are amid an opioid overdose epidemic; we are challenged to provide non-addicting/non-pharmacological alternatives to assist in pain attenuation. There are proven strategies available to manage chronic pain effectively without opioids. Utilization review providers for insurance companies...

Showing 1 to 12 of 44 entries