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Successful control of a case of severe insulin allergy with liraglutide.

Journal of diabetes investigation

Kawanami D, Ito T, Watanabe Y, Kinoshita J, Sakamoto M, Isaka T, Utsunomiya K.
PMID: 24843637
J Diabetes Investig. 2013 Jan 29;4(1):94-6. doi: 10.1111/j.2040-1124.2012.00239.x. Epub 2012 Aug 30.

A 72-year-old woman presented with repeated hypoglycemic and hyperglycemic episodes because of an insulin allergy. On admission, she was diagnosed with type B insulin resistance syndrome. She was also found to have anti-insulin antibodies. After steroid therapy, glycemic control...

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Kawanami D, Ito T, Watanabe Y, et al. Successful control of a case of severe insulin allergy with liraglutide. J Diabetes Investig. 2012;4(1):94-6doi: 10.1111/j.2040-1124.2012.00239.x.
Kawanami, D., Ito, T., Watanabe, Y., Kinoshita, J., Sakamoto, M., Isaka, T., & Utsunomiya, K. (2013). Successful control of a case of severe insulin allergy with liraglutide. Journal of diabetes investigation, 4(1), 94-6. https://doi.org/10.1111/j.2040-1124.2012.00239.x
Kawanami, Daiji, et al. "Successful control of a case of severe insulin allergy with liraglutide." Journal of diabetes investigation vol. 4,1 (2013): 94-6. doi: https://doi.org/10.1111/j.2040-1124.2012.00239.x
Kawanami D, Ito T, Watanabe Y, Kinoshita J, Sakamoto M, Isaka T, Utsunomiya K. Successful control of a case of severe insulin allergy with liraglutide. J Diabetes Investig. 2013 Jan 29;4(1):94-6. doi: 10.1111/j.2040-1124.2012.00239.x. Epub 2012 Aug 30. PMID: 24843637; PMCID: PMC4019294.
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Inhaled human insulin (Exubera(®)): its pharmacologic profile, efficacy and safety in the treatment of adults with diabetes mellitus.

Expert review of clinical pharmacology

Schimke KE, Davis TM.
PMID: 24410506
Expert Rev Clin Pharmacol. 2008 Jan;1(1):13-25. doi: 10.1586/17512433.1.1.13.

Exubera(®) (EXU, insulin human [rDNA origin]) is the first inhaled insulin approved for the treatment of diabetes in adults. Its pharmacokinetic properties make it suitable as therapy for postprandial glycemia. Clinical trials have demonstrated equal efficacy with short-acting subcutaneous...

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Schimke KE, Davis TM. Inhaled human insulin (Exubera(®)): its pharmacologic profile, efficacy and safety in the treatment of adults with diabetes mellitus. Expert Rev Clin Pharmacol. 2008;1(1):13-25doi: 10.1586/17512433.1.1.13.
Schimke, K. E., & Davis, T. M. (2008). Inhaled human insulin (Exubera(®)): its pharmacologic profile, efficacy and safety in the treatment of adults with diabetes mellitus. Expert review of clinical pharmacology, 1(1), 13-25. https://doi.org/10.1586/17512433.1.1.13
Schimke, Katrin E, and Davis, Timothy Me. "Inhaled human insulin (Exubera(®)): its pharmacologic profile, efficacy and safety in the treatment of adults with diabetes mellitus." Expert review of clinical pharmacology vol. 1,1 (2008): 13-25. doi: https://doi.org/10.1586/17512433.1.1.13
Schimke KE, Davis TM. Inhaled human insulin (Exubera(®)): its pharmacologic profile, efficacy and safety in the treatment of adults with diabetes mellitus. Expert Rev Clin Pharmacol. 2008 Jan;1(1):13-25. doi: 10.1586/17512433.1.1.13. PMID: 24410506.
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Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice.

Molecular medicine (Cambridge, Mass.)

Hanes WM, Olofsson PS, Kwan K, Hudson LK, Chavan SS, Pavlov VA, Tracey KJ.
PMID: 26322849
Mol Med. 2015 Nov;21(1):702-708. doi: 10.2119/molmed.2015.00142. Epub 2015 Aug 17.

Type 1 diabetes in mice is characterized by autoimmune destruction of insulin-producing pancreatic β-cells. Disease pathogenesis involves invasion of pancreatic islets by immune cells, including macrophages and T cells, and production of antibodies to self-antigens, including insulin. Activation of...

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Hanes WM, Olofsson PS, Kwan K, et al. Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice. Mol Med. 2015;21(1):702-708doi: 10.2119/molmed.2015.00142.
Hanes, W. M., Olofsson, P. S., Kwan, K., Hudson, L. K., Chavan, S. S., Pavlov, V. A., & Tracey, K. J. (2015). Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice. Molecular medicine (Cambridge, Mass.), 21(1), 702-708. https://doi.org/10.2119/molmed.2015.00142
Hanes, William M, et al. "Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice." Molecular medicine (Cambridge, Mass.) vol. 21,1 (2015): 702-708. doi: https://doi.org/10.2119/molmed.2015.00142
Hanes WM, Olofsson PS, Kwan K, Hudson LK, Chavan SS, Pavlov VA, Tracey KJ. Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice. Mol Med. 2015 Nov;21(1):702-708. doi: 10.2119/molmed.2015.00142. Epub 2015 Aug 17. PMID: 26322849; PMCID: PMC4749496.
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[No title available]

FEBS letters

Zühlke H, Kohnert K, Ziegler M, Knospe S, Behlke J.
PMID: 11945797
FEBS Lett. 1971 May 20;14(5):357-359. doi: 10.1016/0014-5793(71)80300-9.

A component with high molecular weight is prepared from commercial bovine insulin by gel filtration on Sephadex G 50. The substance has little biological and immunological activity in comparison to insulin. The activity is not changed by incubation with...

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Zühlke H, Kohnert K, Ziegler M, et al. Fraktionierung handelsüblichen insulins. Gewinnung und eigenschaften einer hochmolekularen, insulin-ähnlichen komponente. . FEBS Lett. 1971;14(5):357-359doi: 10.1016/0014-5793(71)80300-9.
Zühlke, H., Kohnert, K., Ziegler, M., Knospe, S., & Behlke, J. (1971). Fraktionierung handelsüblichen insulins. Gewinnung und eigenschaften einer hochmolekularen, insulin-ähnlichen komponente. . FEBS letters, 14(5), 357-359. https://doi.org/10.1016/0014-5793(71)80300-9
Zühlke, H, et al. "Fraktionierung handelsüblichen insulins. Gewinnung und eigenschaften einer hochmolekularen, insulin-ähnlichen komponente." . FEBS letters vol. 14,5 (1971): 357-359. doi: https://doi.org/10.1016/0014-5793(71)80300-9
Zühlke H, Kohnert K, Ziegler M, Knospe S, Behlke J. Fraktionierung handelsüblichen insulins. Gewinnung und eigenschaften einer hochmolekularen, insulin-ähnlichen komponente. . FEBS Lett. 1971 May 20;14(5):357-359. doi: 10.1016/0014-5793(71)80300-9. German. PMID: 11945797.
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Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report.

Diabetology & metabolic syndrome

Taboada GF, de Freitas MS, da S Corrêa FH, Junior CR, de B Gomes M.
PMID: 19941665
Diabetol Metab Syndr. 2009 Nov 26;1(1):23. doi: 10.1186/1758-5996-1-23.

Insulin signalling pathways were investigated in a 33 year-old woman with immunologic insulin resistance. Her past medical history was remarkable for intermittent use of insulin and allergic reactions to several drugs, and measure of plasma anti-insulin antibodies level corroborated...

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Taboada GF, de Freitas MS, da S Corrêa FH, et al. Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report. Diabetol Metab Syndr. 2009;1(1):23doi: 10.1186/1758-5996-1-23.
Taboada, G. F., de Freitas, M. S., da S Corrêa, F. H., Junior, C. R., & de B Gomes, M. (2009). Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report. Diabetology & metabolic syndrome, 1(1), 23. https://doi.org/10.1186/1758-5996-1-23
Taboada, Giselle F, et al. "Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report." Diabetology & metabolic syndrome vol. 1,1 (2009): 23. doi: https://doi.org/10.1186/1758-5996-1-23
Taboada GF, de Freitas MS, da S Corrêa FH, Junior CR, de B Gomes M. Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report. Diabetol Metab Syndr. 2009 Nov 26;1(1):23. doi: 10.1186/1758-5996-1-23. PMID: 19941665; PMCID: PMC2789034.
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INSULIN ANTIBODY VARIATIONS IN RABBITS AND GUINEA PIGS AND MULTIPLE ANTIGENIC DETERMINANTS ON INSULIN.

The Journal of experimental medicine

Arquilla ER, Finn J.
PMID: 19867233
J Exp Med. 1963 Jul 01;118(1):55-71. doi: 10.1084/jem.118.1.55.

1. A method is presented for measuring the degree to which insulin antibodies in one antiserum react with an insoluble insulin complex saturated with antibodies from a different antiserum. 2. Many rabbits produce antibodies which bind to portions of...

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Arquilla ER, Finn J. INSULIN ANTIBODY VARIATIONS IN RABBITS AND GUINEA PIGS AND MULTIPLE ANTIGENIC DETERMINANTS ON INSULIN. J Exp Med. 1963;118(1):55-71doi: 10.1084/jem.118.1.55.
Arquilla, E. R., & Finn, J. (1963). INSULIN ANTIBODY VARIATIONS IN RABBITS AND GUINEA PIGS AND MULTIPLE ANTIGENIC DETERMINANTS ON INSULIN. The Journal of experimental medicine, 118(1), 55-71. https://doi.org/10.1084/jem.118.1.55
Arquilla, E R, and Finn, J. "INSULIN ANTIBODY VARIATIONS IN RABBITS AND GUINEA PIGS AND MULTIPLE ANTIGENIC DETERMINANTS ON INSULIN." The Journal of experimental medicine vol. 118,1 (1963): 55-71. doi: https://doi.org/10.1084/jem.118.1.55
Arquilla ER, Finn J. INSULIN ANTIBODY VARIATIONS IN RABBITS AND GUINEA PIGS AND MULTIPLE ANTIGENIC DETERMINANTS ON INSULIN. J Exp Med. 1963 Jul 01;118(1):55-71. doi: 10.1084/jem.118.1.55. PMID: 19867233; PMCID: PMC2137573.
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Recurrent Insulin Autoimmune Syndrome Caused by α-Lipoic Acid in Type 2 Diabetes.

Endocrinology and metabolism (Seoul, Korea)

Bae SM, Bae MN, Kim EY, Kim IK, Seo MW, Shin JK, Cho SR, Jeong GH.
PMID: 24396698
Endocrinol Metab (Seoul). 2013 Dec;28(4):326-30. doi: 10.3803/EnM.2013.28.4.326. Epub 2013 Dec 12.

Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia caused by insulin autoantibodies in the absence of exogenous insulin administration. Some drugs containing sulfhydryl compounds are known to initiate the onset of IAS. A 67-year-old female who had diabetes...

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Bae SM, Bae MN, Kim EY, et al. Recurrent Insulin Autoimmune Syndrome Caused by α-Lipoic Acid in Type 2 Diabetes. Endocrinol Metab (Seoul). 2013;28(4):326-30doi: 10.3803/EnM.2013.28.4.326.
Bae, S. M., Bae, M. N., Kim, E. Y., Kim, I. K., Seo, M. W., Shin, J. K., Cho, S. R., & Jeong, G. H. (2013). Recurrent Insulin Autoimmune Syndrome Caused by α-Lipoic Acid in Type 2 Diabetes. Endocrinology and metabolism (Seoul, Korea), 28(4), 326-30. https://doi.org/10.3803/EnM.2013.28.4.326
Bae, Sang Mook, et al. "Recurrent Insulin Autoimmune Syndrome Caused by α-Lipoic Acid in Type 2 Diabetes." Endocrinology and metabolism (Seoul, Korea) vol. 28,4 (2013): 326-30. doi: https://doi.org/10.3803/EnM.2013.28.4.326
Bae SM, Bae MN, Kim EY, Kim IK, Seo MW, Shin JK, Cho SR, Jeong GH. Recurrent Insulin Autoimmune Syndrome Caused by α-Lipoic Acid in Type 2 Diabetes. Endocrinol Metab (Seoul). 2013 Dec;28(4):326-30. doi: 10.3803/EnM.2013.28.4.326. Epub 2013 Dec 12. PMID: 24396698; PMCID: PMC3871037.
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Ultrasensitive early detection of insulin antibody employing novel electrochemical nano-biosensor based on controllable electro-fabrication process.

Talanta

Farrokhnia M, Amoabediny G, Ebrahimi M, Ganjali M, Arjmand M.
PMID: 34857352
Talanta. 2022 Feb 01;238:122947. doi: 10.1016/j.talanta.2021.122947. Epub 2021 Oct 14.

An ultrasensitive novel electrochemical nano-biosensor for rapid detection of insulin antibodies against diabetes antigens was developed in this research. The presence of insulin antibodies has been demonstrated to be a strong predictor for the development of type 1 diabetes...

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Farrokhnia M, Amoabediny G, Ebrahimi M, et al. Ultrasensitive early detection of insulin antibody employing novel electrochemical nano-biosensor based on controllable electro-fabrication process. Talanta. 2021;238:122947doi: 10.1016/j.talanta.2021.122947.
Farrokhnia, M., Amoabediny, G., Ebrahimi, M., Ganjali, M., & Arjmand, M. (2022). Ultrasensitive early detection of insulin antibody employing novel electrochemical nano-biosensor based on controllable electro-fabrication process. Talanta, 238122947. https://doi.org/10.1016/j.talanta.2021.122947
Farrokhnia, Mohammadreza, et al. "Ultrasensitive early detection of insulin antibody employing novel electrochemical nano-biosensor based on controllable electro-fabrication process." Talanta vol. 238 (2022): 122947. doi: https://doi.org/10.1016/j.talanta.2021.122947
Farrokhnia M, Amoabediny G, Ebrahimi M, Ganjali M, Arjmand M. Ultrasensitive early detection of insulin antibody employing novel electrochemical nano-biosensor based on controllable electro-fabrication process. Talanta. 2022 Feb 01;238:122947. doi: 10.1016/j.talanta.2021.122947. Epub 2021 Oct 14. PMID: 34857352.
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USE OF INHALED INSULIN IN A PATIENT WITH SUBCUTANEOUS INSULIN RESISTANCE SYNDROME: A RARE CONDITION.

AACE clinical case reports

Agarwal S, Gupta M, Gunn S.
PMID: 31967031
AACE Clin Case Rep. 2019 Apr 25;5(3):e187-e191. doi: 10.4158/ACCR-2018-0493. eCollection 2019.

OBJECTIVE: Subcutaneous insulin resistance syndrome (SIRS) is a rare entity, characterized by increased resistance to subcutaneous insulin and normal sensitivity to intravenous insulin, with no increase in circulating insulin antibodies. Little is known about its pathophysiology, but it has...

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Agarwal S, Gupta M, Gunn S. USE OF INHALED INSULIN IN A PATIENT WITH SUBCUTANEOUS INSULIN RESISTANCE SYNDROME: A RARE CONDITION. AACE Clin Case Rep. 2019;5(3):e187-e191doi: 10.4158/ACCR-2018-0493.
Agarwal, S., Gupta, M., & Gunn, S. (2019). USE OF INHALED INSULIN IN A PATIENT WITH SUBCUTANEOUS INSULIN RESISTANCE SYNDROME: A RARE CONDITION. AACE clinical case reports, 5(3), e187-e191. https://doi.org/10.4158/ACCR-2018-0493
Agarwal, Swashti, et al. "USE OF INHALED INSULIN IN A PATIENT WITH SUBCUTANEOUS INSULIN RESISTANCE SYNDROME: A RARE CONDITION." AACE clinical case reports vol. 5,3 (2019): e187-e191. doi: https://doi.org/10.4158/ACCR-2018-0493
Agarwal S, Gupta M, Gunn S. USE OF INHALED INSULIN IN A PATIENT WITH SUBCUTANEOUS INSULIN RESISTANCE SYNDROME: A RARE CONDITION. AACE Clin Case Rep. 2019 Apr 25;5(3):e187-e191. doi: 10.4158/ACCR-2018-0493. eCollection 2019. PMID: 31967031; PMCID: PMC6876942.
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Long-term follow-up of insulin autoimmune syndrome in an elderly patient.

Clinical case reports

Yoshino H, Kawakami K, Kohriyama K, Yoshino G, Matsunaga S, Takechi H.
PMID: 33363855
Clin Case Rep. 2020 Sep 14;8(12):2941-2944. doi: 10.1002/ccr3.3150. eCollection 2020 Dec.

An 84-year-old man was admitted to our hospital. His blood glucose level was 20 mg/dL. Since laboratory tests showed high titers of insulin antibodies, insulin autoimmune syndrome (IAS) was diagnosed. In　order to avoid hypoglycemia, steroids can be effective...

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Yoshino H, Kawakami K, Kohriyama K, et al. Long-term follow-up of insulin autoimmune syndrome in an elderly patient. Clin Case Rep. 2020;8(12):2941-2944doi: 10.1002/ccr3.3150.
Yoshino, H., Kawakami, K., Kohriyama, K., Yoshino, G., Matsunaga, S., & Takechi, H. (2020). Long-term follow-up of insulin autoimmune syndrome in an elderly patient. Clinical case reports, 8(12), 2941-2944. https://doi.org/10.1002/ccr3.3150
Yoshino, Hiroshi, et al. "Long-term follow-up of insulin autoimmune syndrome in an elderly patient." Clinical case reports vol. 8,12 (2020): 2941-2944. doi: https://doi.org/10.1002/ccr3.3150
Yoshino H, Kawakami K, Kohriyama K, Yoshino G, Matsunaga S, Takechi H. Long-term follow-up of insulin autoimmune syndrome in an elderly patient. Clin Case Rep. 2020 Sep 14;8(12):2941-2944. doi: 10.1002/ccr3.3150. eCollection 2020 Dec. PMID: 33363855; PMCID: PMC7752643.
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Insulin autoimmune syndrome in an Argentine woman taking α-lipoic acid: A case report and review of the literature.

SAGE open medical case reports

Izzo V, Greco C, Corradini D, Infante M, Staltari MT, Romano M, Bellia A, Lauro D, Uccioli L.
PMID: 30627435
SAGE Open Med Case Rep. 2018 Dec 26;6:2050313X18819601. doi: 10.1177/2050313X18819601. eCollection 2018.

Insulin autoimmune syndrome is an unusual cause of spontaneous hypoglycaemia in non-Asian populations. In the majority of cases, this syndrome appears a few weeks after the administration of drugs containing a sulfhydryl group. A strong association between this syndrome...

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Izzo V, Greco C, Corradini D, et al. Insulin autoimmune syndrome in an Argentine woman taking α-lipoic acid: A case report and review of the literature. SAGE Open Med Case Rep. 2018;6:2050313X18819601doi: 10.1177/2050313X18819601.
Izzo, V., Greco, C., Corradini, D., Infante, M., Staltari, M. T., Romano, M., Bellia, A., Lauro, D., & Uccioli, L. (2018). Insulin autoimmune syndrome in an Argentine woman taking α-lipoic acid: A case report and review of the literature. SAGE open medical case reports, 62050313X18819601. https://doi.org/10.1177/2050313X18819601
Izzo, Valentina, et al. "Insulin autoimmune syndrome in an Argentine woman taking α-lipoic acid: A case report and review of the literature." SAGE open medical case reports vol. 6 (2018): 2050313X18819601. doi: https://doi.org/10.1177/2050313X18819601
Izzo V, Greco C, Corradini D, Infante M, Staltari MT, Romano M, Bellia A, Lauro D, Uccioli L. Insulin autoimmune syndrome in an Argentine woman taking α-lipoic acid: A case report and review of the literature. SAGE Open Med Case Rep. 2018 Dec 26;6:2050313X18819601. doi: 10.1177/2050313X18819601. eCollection 2018. PMID: 30627435; PMCID: PMC6311546.
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High glycated albumin (GA) levels and the GA/HbA1c ratio in patients with insulin autoimmune syndrome.

Diabetology international

Koga M, Inada S, Taniguchi J, Nakatani Y, Yoshino H, Yoshino G, Okauchi Y, Mineo I.
PMID: 30603322
Diabetol Int. 2016 Nov 04;8(2):199-204. doi: 10.1007/s13340-016-0294-7. eCollection 2017 Jun.

Insulin autoimmune syndrome (IAS) involves not only fasting hypoglycemia, but also postprandial hyperglycemia. In the present study, we hypothesized that glycated albumin (GA) levels and the GA/HbA1c ratio, which reflect fluctuations in plasma glucose levels, are elevated in IAS...

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Koga M, Inada S, Taniguchi J, et al. High glycated albumin (GA) levels and the GA/HbA1c ratio in patients with insulin autoimmune syndrome. Diabetol Int. 2016;8(2):199-204doi: 10.1007/s13340-016-0294-7.
Koga, M., Inada, S., Taniguchi, J., Nakatani, Y., Yoshino, H., Yoshino, G., Okauchi, Y., & Mineo, I. (2017). High glycated albumin (GA) levels and the GA/HbA1c ratio in patients with insulin autoimmune syndrome. Diabetology international, 8(2), 199-204. https://doi.org/10.1007/s13340-016-0294-7
Koga, Masafumi, et al. "High glycated albumin (GA) levels and the GA/HbA1c ratio in patients with insulin autoimmune syndrome." Diabetology international vol. 8,2 (2017): 199-204. doi: https://doi.org/10.1007/s13340-016-0294-7
Koga M, Inada S, Taniguchi J, Nakatani Y, Yoshino H, Yoshino G, Okauchi Y, Mineo I. High glycated albumin (GA) levels and the GA/HbA1c ratio in patients with insulin autoimmune syndrome. Diabetol Int. 2016 Nov 04;8(2):199-204. doi: 10.1007/s13340-016-0294-7. eCollection 2017 Jun. PMID: 30603322; PMCID: PMC6224948.
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Showing 1 to 12 of 59 entries