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Showing 1 to 12 of 2685 entries
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On the origin of elementary hexoses

elementary

Hirabayashi J.
GSID: Vl8V_aa-skcJ
J Hirabayashi - The Quarterly review of biology, 1996 - journals.uchicago.edu

A possible scenario on the origin of elementary hoxoses (fructose, glucose, mannose, and galactose) is proposed: (1) Formol reaction, an autocatalytic polymerization reaction, …

On the pedagogical insight of mathematicians:'Interaction'and 'transition from the concrete to the abstract'

mathematics education

Iannone P.
GSID: WGR5PWLwhk0J
P Iannone, E Nardi - The Journal of Mathematical Behavior, 2005 - Elsevier

In this paper we draw on a 16-month study funded by the Learning and Teaching Support Network in the UK and entitled Mathematicians as Educational Co-Researchers. The study's …

High-energy collision-induced dissociation mass spectrometry of synthetic mannose-6-phosphate oligosaccharides.

Journal of the American Society for Mass Spectrometry

Lipniunas PH, Townsend RR, Burlingame AL, Hindsgaul O.
PMID: 24203240
J Am Soc Mass Spectrom. 1996 Feb;7(2):182-8. doi: 10.1016/1044-0305(95)00635-4.

The high-energy collision-induced dissociation spectra of a series of linear and branched synthetic mannosyl oligosaccharides that contain 6-phosphate substituents on either or both non-reducing terminal or penultimate residues have been studied. These phosphorylated structures were designed to mimic those...

Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy.

Molecular therapy. Methods & clinical development

Liu L, Lee WS, Doray B, Kornfeld S.
PMID: 28480305
Mol Ther Methods Clin Dev. 2017 Mar 29;5:59-65. doi: 10.1016/j.omtm.2017.03.006. eCollection 2017 Jun 16.

Several lysosomal enzymes currently used for enzyme replacement therapy in patients with lysosomal storage diseases contain very low levels of mannose 6-phosphate, limiting their uptake via mannose 6-phosphate receptors on the surface of the deficient cells. These enzymes are...

Inflammatory bowel disease nurse specialists for patients on biological therapies: a nationwide Italian survey.

Annals of gastroenterology

Guarini A, Marinis F, Kohn A, Orzes N, D'Incà R, Iannone T, Giaquinto A, Rivara C, Ridola L, Lorenzetti R, Zullo A.
PMID: 27708516
Ann Gastroenterol. 2016 Oct-Dec;29(4):492-496. doi: 10.20524/aog.2016.0073. Epub 2016 Jul 21.

BACKGROUND: Management of inflammatory bowel disease (IBD) patients requires a multidisciplinary approach. Among the working team, the role of IBD nurse is expected to be particularly relevant when managing patients receiving biological therapies. We performed a survey to assess...

Functional Characterization of a Hexose Transporter from Root Endophyte Piriformospora indica.

Frontiers in microbiology

Rani M, Raj S, Dayaman V, Kumar M, Dua M, Johri AK.
PMID: 27499747
Front Microbiol. 2016 Jul 22;7:1083. doi: 10.3389/fmicb.2016.01083. eCollection 2016.

Understanding the mechanism of photosynthate transfer at symbiotic interface by fungal monosaccharide transporter is of substantial importance. The carbohydrate uptake at the apoplast by the fungus is facilitated by PiHXT5 hexose transporter in root endophytic fungus Piriformospora indica. The...

Faba bean hulls as a potential source of pectin.

Journal of food science and technology

Korish M.
PMID: 26345029
J Food Sci Technol. 2015 Sep;52(9):6061-6. doi: 10.1007/s13197-014-1688-9. Epub 2014 Dec 20.

This study aimed for the first time to assess the potential use of faba bean hulls as a source of pectin. The study involved extracting pectin under various conditions of pH, temperature and extraction time and determining how these...

Erratum to “Proteomic analysis of differential protein expression in Acidithiobacillus ferrooxidans cultivated in high potassium concentration” [Microbiol. Res. 168 (7) (2013) 455–460].

Microbiological research

Ouyang J, Guo W, Li B, Gu L, Zhang H, Xinhua Chen H.
PMID: 27062771
Microbiol Res. 2016 Jan;182:163-8. doi: 10.1016/j.micres.2015.02.004.

Acidithiobacillus ferrooxidans is a chemolithoautotrophic acidophile that oxidizes ferrous iron or sulfur compounds to obtain energy in the presence of various ions. To investigate the potassium ion response of A. ferrooxidans, we conducted a proteomics analysis. We identified eight...

Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis mice.

Annals of clinical and translational neurology

Damme M, Stroobants S, Lüdemann M, Rothaug M, Lüllmann-Rauch R, Beck HC, Ericsson A, Andersson C, Fogh J, D'Hooge R, Saftig P, Blanz J.
PMID: 26817023
Ann Clin Transl Neurol. 2015 Sep 19;2(11):987-1001. doi: 10.1002/acn3.245. eCollection 2015 Nov.

OBJECTIVE: The lysosomal storage disease alpha-mannosidosis is caused by the deficiency of the lysosomal acid hydrolase alpha-mannosidase (LAMAN) leading to lysosomal accumulation of neutral mannose-linked oligosaccharides throughout the body, including the brain. Clinical findings in alpha-mannosidosis include skeletal malformations,...

Cardiovascular disease in HIV patients: from bench to bedside and backwards.

Open heart

Cerrato E, Calcagno A, D'Ascenzo F, Biondi-Zoccai G, Mancone M, Grosso Marra W, Demarie D, Omedè P, Abbate A, Bonora S, DiNicolantonio JJ, Estrada V, Escaned J, Moretti C, Gaita F.
PMID: 25815207
Open Heart. 2015 Mar 20;2(1):e000174. doi: 10.1136/openhrt-2014-000174. eCollection 2015.

HIV patients are exposed to a higher risk of adverse cardiovascular events, due to complex interactions between traditional risk factors and HIV infection itself in terms of ongoing endothelial dysfunctional immune activation/inflammation and increased risk of thrombosis. On the...

PO-20 - Crosstalk between the lectin pathway and haemostasis in patients with pulmonary cancer.

Thrombosis research

Larsen JB, Christensen TD, Hvas CL, Hvas AM.
PMID: 27161707
Thromb Res. 2016 Apr;140:S183. doi: 10.1016/S0049-3848(16)30153-0. Epub 2016 Apr 08.

INTRODUCTION: Recent research has focused on the complement system in cancer, including the lectin pathway of complement activation. Mannose-binding lectin (MBL), a key activator of the lectin pathway, can bind to tumor cell surfaces in vitro, and lectin pathway...

Ultrasound-assisted extraction of polysaccharides from Artemisia selengensis Turcz and its antioxidant and anticancer activities.

Journal of food science and technology

Wang J, Lu HD, Muḥammad U, Han JZ, Wei ZH, Lu ZX, Bie XM, Lu FX.
PMID: 27162382
J Food Sci Technol. 2016 Feb;53(2):1025-1034. doi: 10.1007/s13197-015-2156-x. Epub 2016 Jan 04.

Artemisia selengensis Turcz (AST) is a perennial herb with therapeutic and economic applications in China. The effects of ultrasound-assisted extraction (UAE) parameters upon extraction yield (EY%), antioxidant and antitumor activities of the polysaccharides extracts were studied by using a...

Showing 1 to 12 of 2685 entries